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STUDY ON ANTHROPOMETRIC AND BIOCHEMICAL INDICATORS OF PATIENTS WITH DIABETES AND IMPAIRED GLUCOSE REGULATION IN UYGUR

Hong DING ; Jie SHAO ; Wei ZHE ; Yueming ZHANG

Acta Nutrimenta Sinica.2004;0(06):-.

40 years old in 6 Uygur communities of Urumqi. The multi-phasic stratified cluster sampling method was adopted. Finally 191 men with high risk were selected as samples in the study and classified into two groups according to oral glucose tolerance test(OGTT)results, anthropometric and biochemical indicators. Results The prevalence of type 2 diabetes and IGR was 17.39% and 7.56% respecfively in the Uygur nationality. Waist-hip ratio, abdominal and waist circumference,the level of HbA1c and serum insulin of male diabetic patients were significantly higher than those of male IGR potieuts. But another four indicators of blood lipid and three indicators of renal function were not significantly different between two groups. Conclusion The indicators releted to abdominal obesity may be sensitive to diabetes and valuable to screen diabetic patients for giving effective health education and behavioral intervention in high risk population.

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GINSENOSIDE FACILITATES LEARNING AND MEMORY IN AGED MICE

Dong LI ; Haifeng HOU

Acta Nutrimenta Sinica.2004;0(06):-.

Objective To investigate the effect of ginsenoside on degeneration of learning and memory in aged mice and the mechanism. Method Eighty female C57BL/6J mice aged 20-mo were randomly divided into control group and three ginsenoside treatment groups at dosage of 25,50,100 mg/(kg bw?d) respectively by drinking. In addition, 20 female C57BL/6J mice aged 3 mo were used to be young control group. Eight mo later, the learning and memory abilities of the mice were checked by Morris water maze. Thereafter, the mice were killed by decapitation,and their serum was collected to determine the level of SOD, GSH-Px and MDA. Hippocampal morphology was examined by Nissl stain; and the expression of brain-derived neurotrophic factor (BDNF) in hippocampus was studied using Western blot method. Results 50,100 mg/(kg bw?d) ginsenosides administration could significantly shorten the escape latency of the aged mice in Morris water maze. Furthermore,the alleviated oxidative stress and up-regulated expression of BDNF were observed in 50, 100 (mg/kg?d) ginsenosides groups compared with aged control group. Serum level of GSH-Px was higher in 25 (mg/kg bw?d) ginsenosides group compared to that of aged control group. The number of Nissl-positive cell had no significant difference between all groups. Conclusion 50,100 mg/(kg bw?d) ginsenoside can significantly delay the degeneration of learning and memory in aged mice by lowering oxidative damage and up-regulating BDNF expression in hippocampus.

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EFFECTS OF GINKGO BILOBA EXTRACT ON FREE RADICAL METABOLISM OF DIFFERENT FIBER TYPES OF QUADRICEPS IN EXERCISED RATS

Wenjian LI ; Zeyi YANG ; Zongdao CHEN

Acta Nutrimenta Sinica.2004;0(06):-.

Objective To study the effects of Ginkgo biloba extract (GBE) on free radical metabolism of different fiber types of quadriceps in exercised rats and its mechanism. Method Increasing load exercised rat model was selected. The test rats were orally given GBE aqueous suspension (100 mg/ kg?d), and the controls with water. The levels of malondialdehyde (MDA) and the activities of total superoxide dismutase (T-SOD), glutathione peroxidase (GSH-Px) of red muscle, white muscle and whole quadriceps of exercised rats were examined before exhaustive exercise, at instant,24h and 48h after strenuous exhaustive exercise. Results Compared with the controls,MDA contents were 49.69% higher in white muscle (P

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Inhibition to S_(180) Sarcoma of Polysaccharide in Longan (Dimocarpus longan Lour.)

Shaoquan ZHENG ; Jingui ZHENG

Acta Nutrimenta Sinica.2004;0(06):-.

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THE CHINESE DIET BALANCE INDEX REVISED

Yuna HE ; Fengying ZHAI ; Xiaoguang YANG ; Keyou GE

Acta Nutrimenta Sinica.2004;0(06):-.

To revise Chinese Diet Balance Index (DBI) based on the current Chinese Dietary Guidelines and Food Guide Pagoda . Method: Seven food components [(cereals ,vegetables and fruits, bean and dairy , animal food , alcohol ,condiments (salt and edible oil))were selected in combination with food varieties and drinking water to build up Diet Balance Index Revision (DBI-07) .The components were weighed and assigned cut-offs and scores based on the Chinese Food Guide Pagoda. Three scoring methods (LBS-low bound score, HBS-high bound score, DQD-diet quality distance) were used to evaluate the dietary quality of 26300 adults aged 18 to 79 years from 2002 China National Nutrition and Health Survey. Results: The mean LBS, HBS and DQD were 11.5,30.0 and 41.5 respectively. About 78% adult were in moderate or severe deficit of food intake, 35.1% in moderate or severe surplus of food intake, and 43.8% in severe dietary imbalance. Conclusion: DBI-07 can reflect the principles of dietary guidelines, and the scoring method can reflect both deficit and surplus of food intake. DBI-07 can be used to evaluate the dietary quality of individual or the population.

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STUDY ON PHYSICOCHEMICAL PROPERTY OF THE COMPONENT-FE COMPLEX OF AURICULARIA AURICULA

Yongjun ZHANG ; Qiao XIAN ; Zhenyou CAI ; Dandan XIANG

Acta Nutrimenta Sinica.2004;0(06):-.

Objective To compare the chemical composition of Auricularia auricula polysaccharide and the colloid, and the property of the different component-Fe complex. Method Auricularia auricula polysaccharide and the colloid were prepared first, then Auricularia auricula polysaccharide iron complex (APIC)and Aurcularia auricula glia iron complex (AGIC) were synthesized respectively with FeCl3 under alkaline condition, and their physicochemical property was determined. Results The stablility of AGIC was better than APIC and AGIC could be reduced to Fe(Ⅱ)by ascorbic acid more easily. Conclusion The Auricularia auricula colloid could combine with Fe(Ⅲ)easier than the polysaccharide, and would be expected to become a higher bioavailable iron-supplement.

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STUDY ON THE EFFECT OF PORPHYRA POWDER ON THE FUNCTION OF DEFECATION

Haimin CHEN ; Qijun LUO ; Luqing PEI ; Long DI ; Jilin XU ; Xiaojun YAN

Acta Nutrimenta Sinica.2004;0(06):-.

Objective To study the effect of diet containing different proportions of porphyra powder on relieving constipation, volatile organic compounds and inhibiting intestinal E. coli. Method Mice were divided into 3 groups: blank group, 2 test groups. After the mice were allotted for different concentrations of porphyra powder diet for 30 d, the body weight of mice, water-holding capacity, the number and weight of feces within 24 h, the feces pH, E. coli counts and the first black defecating time were detected. The odorous compounds in feces were also measured by headspace solid phase microextraction coupled with GC-MS. Results Compared with the blank group, the water absorbed and number and weight of feces were significantly increased(P

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STUDY ON THE PROTECTIVE EFFECT OF SINAPINE AGAINST RADIATION TO DROSOPHILA

Dejuan HUANG ; Weiyue XU ; Dechao HUANG

Acta Nutrimenta Sinica.2004;0(06):-.

Objective To investigate the antiradiation effect of sinapine in Drosophita. Method Sinapine in cauliflower was quantified by HPLC, and added in Drosophila culture substrate. We observed the effect of sinapine from cauliflower on reproductive rate, sex ratio, mutation rate of Drosophila after UV radiation. Results Sinapine in cauliflower contained 4.429 ?g/ml thiocyanate. After adding sinapine thiocyanate 0.29075 mg/ml to the media,the reproductive rate of UV irradiated Drosophila culture increased 27.083%, the sex ratio (female/male) and mutation rate declined 23.457% and 97.202% respectively, and the growth cycle became normal again. Conclusion Cauliflower’s sinapine thiocynate has quite favorable anti-radiation function.

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STUDIES ON THE SERIAL PRODUCTS OF ENTERMORPHA WITH ITS DEFECATION FUNCTIONS

Wenting LIN ; Pingping ZHU ; Liyun ZHONG

Acta Nutrimenta Sinica.2004;0(06):-.

Objective To study the effect of the products of entermorpha (EP), chlorella growth factor (CGF) and entermorpha dietary fiber (EPDF) on defecation and blood lipid regulation. Method Based on the composition of EP products, the male ICR mice were intervened with EP, EPDF and CGF with three doses. Using the constipation model induced by compound diphenoxylate, the effect of EP products on enterocinesia function of mice was determined by measuring defecation and the percentage of ink-pushing in small intestine. High-lipid rat model was established by feading high fat diet and the intervention effect with three doses of EPDF and CGF for 6 w was observed. Results As compared to the model group,all doses of EP,both middle and high doses of EPDF,and high dose of CGF could shorten the time of first defecation and increase the percentage of ink-pushing in small intestine of costive mice (P

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EFFECT OF PINE-SEED OIL ON LIPID METABOLISM-RELATED GENE EXPRESSION IN ADIPOSE TISSUE OF MICE

Rong LIU ; Xianghong WANG ; Yanmei YANG ; Xiuli CHEN

Acta Nutrimenta Sinica.2004;0(06):-.

Objective To study the influence of pine-seed oil on lipid metabolism-related gene expression. Method The mice were fed by basic food,high fat food (80% basic food added 20% lard, HF) and HF added pine-seed oil (80% high fat food added 20% pine-seed oil, SHF). At 45 d and 90 d, the ACS mRNA, FATP mRNA, HSL mRNA and PPAR mRNA of adipose tissue were measured respectively by RT-PCR. Results At 45 d, compared with the basic group, ACS mRNA, FATP mRNA, HSL mRNA and PPAR-? mRNA expression level in SHF group increased by 24.2%, 8.8%, 10.9%, 21.6% respectively,and at 90 d,increased by 19.6%, 25.7%, 60.1%, 13.1% respectirely. Compared with the basic group,ACS mRNA, FATP mRNA, HSL mRNA and PPAR-? mRNA expression level in HF group increased by 27.9%, 41.7%, 51.1%, 23.9% respectively. Conclusion Pine-seed oil is significantly effective in regulation of lipid metabolism.

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