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Chinese Journal of Radiological Health

1992  (1,  1)  to  Present  ISSN: 1004-714X

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Measurement and analysis of peak skin dose for patients withinterventional cardiology procedures

Qiaoqiao ZHAO ; Yaohua FAN ; Zhuo HUANG ; Hui XU ; Xiangming OU

Chinese Journal of Radiological Health.2024;33(3):229-233. doi:10.13491/j.issn.1004-714X.2024.03.001

Objective  : To obtain the peak skin dose (PSD) of patients with interventional cardiology procedures and toevaluate the risk of deterministic effects. Methods  : Gafchromic XR RV3 films were used in a Level A tertiary hospital inBeijing to measure the PSD of patients who underwent interventional cardiology procedures. The measurement focused onfour common types of procedures, including coronary angiography, percutaneous transluminal coronary angioplasty,cathet-er radiofrequency ablation, and congenital heart disease. The films were scanned by EPSON EXPRESSION 10000XL andanalyzed by FILM QA ProTM 2014 software. Results  : PSD was measured in 59 patients with interventional cardiologypro-cedures, including 23 with coronary angiography, 21 with percutaneous transluminal coronary angioplasty, 9 with catheterradiofrequency ablation, and 6 with congenital heart disease. The seven patients with PSD ≥ 2 Gy all underwentpercu-taneous transluminal coronary angioplasty, one with PSD > 3 Gy and six with PSD < 2 Gy. Conclusion  The PSD of somepatients with interventional cardiology surgery exceeded the dose threshold of deterministic effects recommended by theICRP 118. There is a risk of deterministic effects in interventional cardiology surgery, especially in patients withpercu-taneous transluminal coronary angioplasty.

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Calculation of organ dose of 90Y TheraSphere in the treatment of pancreatic cancer

Jiangxia WANG ; Wei WANG ; Chuangao WANG ; Jinsen GUO ; Hongchao PANG

Chinese Journal of Radiological Health.2024;33(3):234-241. doi:10.13491/j.issn.1004-714X.2024.03.002

Objective To calculate the absorbed dose of 90Y TheraSphere in the pancreas and the surrounding sensitive organs after the administration in the treatment of pancreatic cancer through the establishment of an individual voxel model, and to provide technical support for the clinical application of 90Y TheraSphere in the treatment of pancreatic cancer. Methods An individualized voxel model was constructed in Geant4 software based on the CT images of the patient. 12 monoenergetic electron specific absorption fractions (SAFs) in the range of 0.01 to 1 MeV were calculated and validated against the ICRP data. The model and method were used to calculate the absorbed doses in the target organs under uniform and nonuniform distribution of 90Y microspheres in the pancreas. Results The relative errors between the SAF values calculated based on the individualized voxel model and the ICRP data after mass calibration were less than 3.89%. When 90Y was uniformly distributed in the pancreas, the absorbed dose in the pancreas was 4.69 × 10−7 Gy/Bq; the absorbed doses in the liver, kidneys, and spleen were 6.15 × 10−12, 6 × 10−12, and 1.65 × 10−11 Gy/Bq, respectively. When 90Y was distributed within the tumor, the absorbed dose in the tumor was 6.69 × 10−6 Gy/Bq and the absorbed dose in normal pancreas was 5.72 × 10−8 Gy/Bq. The fitted relationship between tumor volume V and administered activity A at the prescribed dose of 120 Gy was quadratic, with relatively low activity required for concentrated administration in the center of the tumor. Conclusion The Monte Carlo dose calculation method based on individual voxel model accurately predicted the absorbed doses in the surrounding sensitive organs (liver, kidneys, and spleen) when 90Y TheraSphere was used to treat pancreatic cancer. These results and the analysis of the factors affecting the drug delivery activity will provide data support for the clinical research of 90Y TheraSphere in pancreatic cancer.

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Impact of radioactive impurity nuclides in 90Y microspheres on the therapeutic dose of pancreatic tumors

Wen LUO ; Jinsen GUO ; Wei WANG ; Ling CHEN

Chinese Journal of Radiological Health.2024;33(3):242-247. doi:10.13491/j.issn.1004-714X.2024.03.003

Objective To evaluate the effects of radioactive impurity nuclides in 90Y glass microsphere on therapeutic dose during radioembolization of pancreatic cancer. To provide a reference for correction of the dose calculated for individuals with different pancreatic tumors. Methods In this study, the radioactive impurity nuclide composition of 90Y glass microsphere samples was analyzed to determine the source term of Monte Carlo calculation. Then, according to the PET/CT medical imaging data of pancreatic cancer patients, the three-dimensional modeling software Solidworks 2020 was used to construct the real and personalized digital human digestive system model of pancreatic cancer patients at a resolution showing the vascular distribution in pancreas and tumor. Finally, the Monte Carlo program GATE 8.2 was used to simulate the three-dimensional radiation dose fields of radioactive impurity nuclides 91Y and 65Zn from 90Y glass microspheres in various tissues and organs. The three-dimensional dose fields were visualized to analyze the influence of radioactive impurity nuclides on therapeutic dose. Results The three-dimensional radiation dose fields of 91Y and 65Zn from 90Y glass microspheres demonstrated two dose extreme points. The maximum dose value of 91Y to tissue was 0.272 mGy and the maximum dose value of 65Zn to tissue was 9.34 μGy, with average statistical errors of less than 3.2%. Conclusion The impact of radioactive impurity nuclides 91Y and 65Zn in 90Y glass microsphere sample on therapeutic dose is minimal and can be neglected.

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Monte Carlo simulation analysis of the design of a medical electron linear accelerator maze

Peng TONG ; Changsong HOU ; Jianfei LU ; Weiguo ZHU

Chinese Journal of Radiological Health.2024;33(3):248-253. doi:10.13491/j.issn.1004-714X.2024.03.004

Objective To analyze the impact of different maze structures of medical electron linear accelerator on the radiation level at the entrance of the treatment room. Methods The Monte Carlo simulation method was used to compare the radiation field distribution in two accelerator rooms with different maze widths and to conduct a detailed analysis of the radiation levels. Results The radiation level at the entrance of the accelerator room with a wide maze was significantly higher than that at the entrance of a compact maze. The neutron radiation level at the entrance of the narrow maze model decreased by 38.6% compared to the wide maze model, and the level of X-ray radiation also showed a declining trend. Conclusion When designing medical electron linear accelerators, a compact maze structure should be adopted to reduce the setting of unnecessary space, thereby lowering the radiation level at the entrance of the treatment room and enhancing the effectiveness of radiation protection.

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Analysis of the shielding effect of protective door of an 18 MV linear accelerator debugging room and its influencing factors

Guohai ZHANG ; Bin ZHANG ; Guiying ZHANG ; Yongzhong MA

Chinese Journal of Radiological Health.2024;33(3):254-259. doi:10.13491/j.issn.1004-714X.2024.03.005

Objective To study the shielding effect of the protective door of a maze-free debugging room for an 18 MV medical linear accelerator and its influencing factors, and to provide guidance for protection of debugging personal against radioactive occupational disease hazards. Methods The investigation focused on the protective door of a newly constructed maze-free debugging room for an 18 MV medical linear accelerator. The protective door was made of the following shielding materials from inside to outside: 2.5 cm steel plate + 20 cm lead + 41 cm polyethylene containing 5% boron + 6 cm lead + 2.5 cm steel plate. The right side of the protective door was provided with a groove (commonly known as “door pocket”) lap. With different lap widths, irradiation directions, and installation positions of the accelerator base, FLUKE451P and WENDI II neutron detectors were used to measure the ambient dose equivalent rate of the points of interest outside the protective door. The shielding effect and influencing factors were analyzed. Results When the lap width at both sides of the protective door was 300 mm, the ambient dose equivalent rates outside the protective door were (1.37 ± 0.05) μSv/h on the side with “door pocket” and (4.71 ± 0.11) and (4.19 ± 0.11) μSv/h on the side without “door pocket”. When the primary beam of the accelerator was directed towards the east, the ambient dose equivalent rates at the points of interest outside the protective door were higher than those of the corresponding points of interest when the primary beam was directed towards other directions. When the accelerator base was located on the south side of the machine room, the ambient dose equivalent rates of the points of interest outside the protective door under the same irradiation conditions were lower than those when the accelerator base was located on the north side of the machine room. Conclusion The study of an 18 MV accelerator and its maze-free debugging room showed that the radiation of photons and neutrons should be taken into consideration when designing the protective door at the entrance. The protective door with shiplaps on both sides of the wall has improved shielding effect outside the door.

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Simulation and analysis of an imaging detection device for wound contamination caused by transuranic nuclides

Yujian WANG ; Wei WANG ; Xinglong LI ; Chuangao WANG ; Hongchao PANG ; Ling CHEN

Chinese Journal of Radiological Health.2024;33(3):260-266. doi:10.13491/j.issn.1004-714X.2024.03.006

Objective To address the radioactive contamination of wounds caused by transuranic nuclides, wound radiation imaging based on coded aperture imaging technology was investigated. Methods By simulating multiple source terms using Monte Carlo method, the differences in imaging performance between two image reconstruction algorithms under near-field conditions were compared. The effects of detector pixels and detection plane pixels on image resolution were investigated. Results The imaging system was simulated based on the designed dimensions. The simulated imaging field of view was 89.4 mm × 89.4 mm and the simulated angular resolution was 1.98°. Based on the comparison of the average width at half height of the reconstructed point sources under different conditions, it was found that increasing the number of pixels in the detector and detection plane optimized the angular resolution but significantly prolonged the Monte Carlo simulation time. Conclusion According to the simulation results, the parameters of the imaging system can be used to effectively image radioactive contamination. Our results provide methodological support for the measurement of wound contamination caused by transuranic nuclides, and lay the foundation for the development of wound contamination imaging detection systems in the future.

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Quantitative detection of tiny amounts of tritium in hydrogen using the catalytic oxidation-liquid scintillation counting method

Chao WU ; Binyong ZHANG ; Ying REN ; Yan LIU ; Lebin LI

Chinese Journal of Radiological Health.2024;33(3):267-272. doi:10.13491/j.issn.1004-714X.2024.03.007

Objective To establish a method for quantitative analysis of tiny amounts of tritium in hydrogen below the detection limit of isotope ratio mass spectrometer. Methods Hydrogen was oxidized to produce water in a self-developed catalytic oxidation device filled with platinum hydrophobic catalyst. The effects of different experimental conditions on hydrogen conversion rate were investigated. The tritium concentration in the synthetic water was measured using a liquid scintillation counter. The tritium concentration in hydrogen was calculated according to the measurement of the synthetic water. Results When the flow rate of hydrogen was fixed, the conversion rate of hydrogen increased with the increase of the reaction temperature but increased and then decreased with the increase of the flow rate of oxygen. Hydrogen could be completely converted under optimal experimental conditions. The hydrogen samples with volumetric tritium concentrations in the range of 1 × 10−7 to 2 × 10−14 were converted to water at the reaction temperature of 110 ℃ and hydrogen/oxygen flow rate of 100 mL/min. The resulting water was measured using a liquid scintillation counter. The measurement accuracy was better than 2%. Conclusion This method can be used to measure hydrogen samples with tiny amounts of tritium below the detection limit of isotope ratio mass spectrometer. Our results provide data support for the calculation of the separation capacity of cryogenic distillation process.

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Influence of storage temperature and storage time on the optically stimulated luminescence characteristics of chip resistors in dose reconstruction for nuclear accident

Junlin WANG ; Jianhua WU ; Yang LIU ; Ling CHEN

Chinese Journal of Radiological Health.2024;33(3):273-277. doi:10.13491/j.issn.1004-714X.2024.03.008

Objective To assess the feasibility of employing chip resistors for retrospective dose reconstruction following nuclear accidents, to examine the effects of storage temperature and storage time on the optically stimulated luminescence (OSL) characteristics of the chip resistors, and to explore measures to mitigate these effects. Methods Chip resistors were analyzed using automated instruments for measuring thermoluminescence and OSL manufactured by Risø in Denmark with various parameters to understand the impact of storage temperature and storage time on OSL signals. Results The OSL signals of chip resistors exhibited exponential attenuation within 10 min after irradiation, and then stabilized (count change < 10%) within 2-7 days of storage. The chip resistors exhibited linear dose responses within 1-3 days of storage after 0.1-2 Gy irradiation. OSL signals diminished as the storage temperature increased. However, preheating at 130 ℃ for 1 min effectively eliminated the differences caused by temperatures between 25 ℃ and 45 ℃. Conclusion The OSL signals of chip resistors are influenced by storage temperature and storage time. When preheated at 130 ℃ for 1 min, chip resistors stored for 1-7 days and at 25-45 ℃ exhibited OSL signal errors of 10% or less. This result emphasizes the importance of preheating for measurements in practical applications, thus providing a scientific approach and a solid foundation for the use of chip resistors in retrospective dose reconstruction.

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Effects of 241Am standard material powder with different matrices on the determination of gross alpha activity in water

Yaru SUN ; Fuyou FAN ; Huan WANG ; Meinan YAO ; Bin BAI ; Yongzhong MA

Chinese Journal of Radiological Health.2024;33(3):278-282. doi:10.13491/j.issn.1004-714X.2024.03.009

Objective To understand the effects of 241Am standard material powder with different matrices on the determination of gross alpha activity in water, and to provide a reference for the selection and use of alpha standard sources. Methods The alpha counting efficiency of 241Am standard material powder with different matrices was measured by low-background alpha and beta measuring instrument. The radiochemical recovery rate and whole process efficiency of gross alpha activity in water were determined by spike experiments. Results The alpha counting efficiency of the 241Am standard material powder with four matrices was in the descending order of calcium carbonate, calcium carbonate and silica mixed matrix, calcium sulfate, and silica. The default chemical recovery rate is 1 when gross alpha activity in water is measured by thick source method. The use of 241Am standard material with calcium carbonate as a matrix resulted in about 35% decrease in gross alpha activity, and about 10% deviation was observed using 241Am standard material with silica or calcium carbonate and silica mixed matrices. The whole process efficiency of alpha activity in four spiked water samples with 241Am standard solution and 241Am standard material powder with calcium carbonate, silica, or mixed matrix was 6.34%-7.30%. Conclusion Standard materials with different matrices demonstrate different self-absorption of alpha particles and various influence on the chemical recovery. When purchasing and using standard material powders for alpha activity measurement in laboratories, the composition of the matrix should be clarified as much as possible, and the gross alpha activity in water should be determined by measuring the whole process efficiency if necessary.

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Transfer of cascade coincidence summing correction factors

Lingnan KONG ; Baolu YANG ; Zhenglin YE ; Jing ZHANG ; Qiang ZHOU

Chinese Journal of Radiological Health.2024;33(3):283-287. doi:10.13491/j.issn.1004-714X.2024.03.010

Objective To further extend the application of coincidence summing correction factor transfer experiments through the analysis of relevant measurements. Methods The passive efficiency was simulated using BE5030 high-purity germanium (HPGe) γ-energy spectrometer equipped with LabSOCS, and the total efficiency was simulated using LabSOCS in GENIE 2000 spectrum analysis software, which was used for calculating the coincidence summing correction factor. The coincidence summing correction factor transfer experiments were performed using the measurements with the point source containing 134Cs, 60Co, and 137Cs as well as the body source to obtain the coincidence summing correction factors of other HPGe γ-energy spectrometers. Results The coincidence summing correction factors for 134Cs and 60Co were obtained using the BE5030 γ-energy spectrum. In verification by certificate activity, the absolute value of the maximum deviation was within 3.53%. Using coincidence summing correction factor transfer experiments, these factors were transferred to other high-purity germanium γ spectrometers. In verification by certificate activity, the absolute value of the maximum deviation was within 5.86%. Conclusion The coincidence summing correction factors calculated using simulated total efficiency by calling LabSOCS in the GENIE 2000 spectrum analysis software are effective in correction, and can be used as correction factors in standard laboratories. Through coincidence summing correction factor transfer experiments, the coincidence summing correction of other high-purity germanium γ-energy spectrometers can be achieved, which broadens the application of coincidence summing correction method.

Country

China

Publisher

Editorial Department of Chinese Journal of Radiological Health

ElectronicLinks

http://www.zgfsws.com

Editor-in-chief

Prof. Xu Su

E-mail

redi@chinajournal.net.cn

Abbreviation

Chin J Radiol Health

Vernacular Journal Title

中国辐射卫生

ISSN

1004-714X

EISSN

1004-7140

Year Approved

2022

Current Indexing Status

Currently Indexed

Start Year

1992

Description

Chinese Journal of Radiological Health, which was founded in 1992, is a peer-reviewed bimonthly journal supervised by the National Health Commission of the People’s Republic of China and co-sponsored by Institute of Radiation Medicine, Shandong Academy of Medical Sciences and Chinese Preventive Medicine Association. As a serial journal of Chinese Preventive Medicine Association, Chinese Journal of Radiological Health, based on protection of the health of general populations and radiological healthcare professionals, a leading scientific journal for advancing the research and practice in the field of radiological health sciences in China with major purposes to publicize the policy, laws, regulations and guidelines of Chinese national health and report the novel outcomes, tools, products and information in the field of radiological health sciences. Chinese Journal of Radiological Health provides an important platform for rapid publication of the latest findings, approaches, and viewpoints related to radiological health sciences, and the journal bridges research scientists, teachers, physicians, environmental protection workers and policy-makers working on diverse disciplinary of radiological health sciences for academic exchanges of their latest findings and experiences. Article types accepted include research articles, review articles, opinions and book reviews. These should focus on multi-disciplinary research, public health, environmental protection, health administration, engineering technology or clinical topics in radiological health sciences. Papers should advance the scientific knowledge of the epidemiology, diagnosis, prevention, treatment, and management related to radiological health sciences. With the improvement of academic level and editorial quality, the journal has been covered in international and national bibliographic databases, including International Nuclear Information System (INIS), Ulrich's Periodicals Directory, ScienceOpen, China Scientific and Technical Papers and Citations database, Chinese Citation database, Chinese Core Periodicals database. Chinese Journal of Radiological Health will not consider submissions that have been accepted for publication or published elsewhere. The full requirements for submission, including our conflicts of interest disclosure and ethics policies are described in detail in the journal website and guidelines for authors. All submissions to Chinese Journal of Radiological Health are made using an online submission and peer review system. Registration and access are available at http://www.zgfsws.com/Journalx_zgfsws/authorLogOn.action. Each author must disclose all financial relationships related to the subject of the paper. This should include equity ownership, profit-sharing agreements, royalties, patents, and grants. Authors do not need to report the sums concerned. If none, state “none” in the text. Currently, Chinese Journal of Radiological Health builds a strong editorial board and an active junior editorial board. Led by Prof. Jinming Yu as the honorary Editor-in-Chief, Academician of Chinese Academy of Sciences, Prof. Xu Su as the Editor-in-Chief, Chief Scientist of National Institute of Radiological Protection, Chinese Center for Disease Control and Prevention and Prof. Jianguo Zhu as the executive Editor-in-Chief, Director of Institute of Radiation Medicine, Shandong Academy of Medical Sciences, the editorial board of Chinese Journal of Radiological Health is made up of a broad mix of international and national leading scientists working on radiological health sciences. To facilitate the high-quality publication, Chinese Journal of Radiological Health builds a strong editorial office, led by Dr. Hailiang Li, a well-trained medical radiologist with more than 20 years working in radiological health sciences. Chinese Journal of Radiological Health subjects all submitted research articles to the highest standards of international peer review: (1) At least two suitably qualified experts review each research article; (2) The journals’ Editor-in-Chief makes all publication decisions based on the reviews provided; (3) The Editorial Board Members assist the Editor-in-Chief in decision making on specific submissions; (4) The Editorial Board Members lend insight, advice, and guidance to the Editors-in-Chief. Administrative support for the review process is provided by the Managing Editor, Dr. Hailiang Li. He upholds the integrity of peer review while delivering rapid turnaround and maximum efficiency to all stakeholders including authors, reviewers, and editors alike. The journal uses a single blind, published peer review process whereby the identities of authors and reviewers remain anonymous during the review period with the names of the reviewers subsequently published with the final accepted article. Reviewers primarily evaluate the originality, validity and importance of the manuscripts, and provide detailed and evidence-based (with references) comments to help editors to make publication decisions (accept, revise or reject) and authors to make improvements. The following points are considered during the review process: (1) Is the manuscript suitable for Chinese Journal of Radiological Health? Is it original and important? The topic should be within the scope of the journal and should be of interest to the readers. Reviewers also need to judge the originality and importance of the manuscript. (2) Are the results and conclusions well-supported? Reviewers should highlight if the data are incomplete, insufficient, or if there are errors, because the data may fail to lead to the results and thus the conclusions. (3) Are there any problems regarding statistics? The statistics reviewer needs to make sure there are no flaws or errors regarding statistical methods and analyses. (4) Confidentiality. Reviewers should respect and observe the confidentiality of the manuscript. Chinese Journal of Radiological Health subscribes fully to the COPE code of conduct and best practice for journal editors ensuring that the journal editors are responsible for everything published in our journal. The journal readers will always be informed about how the research is funded and the relationships of journal editors and editorial board members with authors, reviewers and editorial board members will be influenced by COPE recommendations.

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