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Rare Locations of Schwannomas: A Few Comments.

Mohamed Amin GHOBADIFAR

Brain Tumor Research and Treatment.2015;3(1):64-64. doi:10.14791/btrt.2015.3.1.64

No abstract available.
Neurilemmoma*

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Granular Cell Tumor in the Pituitary Stalk: A Case Report.

Soo Jeong PARK ; Youn Hyuk CHANG ; Na Rae YANG ; Eui Kyo SEO

Brain Tumor Research and Treatment.2015;3(1):60-63. doi:10.14791/btrt.2015.3.1.60

Granular cell tumors (GCTs) have been reported in various tissues, especially the skin and subcutaneous soft tissue of the head and neck. We report a 60-year-old man who presented with intermittent headache and dizziness for 3 months, but no other neurological symptoms. Magnetic resonance imaging (MRI) showed the presence of a mass in the pituitary stalk, and contrast-enhanced MRI showed nodular enhancement in this region. The lesion was completely excised microscopically via a frontotemporal (pterional) approach. On pathological examination, a final diagnosis of a typical GCT was made.
Diagnosis ; Dizziness ; Granular Cell Tumor* ; Head ; Headache ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Neck ; Pituitary Gland* ; Pituitary Neoplasms ; Skin

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The Olfactory Groove Schwannoma Attached to the Cribriform Plate: A Case Report.

Deok Young KIM ; Pyeong Ho YOON ; Jeong Hae KIE ; Kook Hee YANG

Brain Tumor Research and Treatment.2015;3(1):56-59. doi:10.14791/btrt.2015.3.1.56

The olfactory groove schwannoma is a quite rare tumor. We report a case of a 49-year-old woman with an olfactory groove schwannoma attached to the cribriform plate without olfactory dysfunction. She had no specific neurological symptoms other than a headache, and resection of the tumor showed it to be a schwannoma. About 19 months after the operation, a follow-up MRI showed no evidence of tumor recurrence. Surgical resection through subfrontal approach could be one of the curative modality in managing an olfactory groove schwannoma. An olfactory groove schwannoma should be considered in the differential diagnosis of anterior skull base tumors.
Diagnosis, Differential ; Ethmoid Bone* ; Female ; Follow-Up Studies ; Headache ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Neurilemmoma* ; Prefrontal Cortex ; Recurrence ; Skull Base

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An Unusual Variant of Anlage Tumor of Pineal Region in an Infant.

Raghvendra RAMDASI ; Kanchan KOTHARI ; Naina GOEL ; Amit MAHORE

Brain Tumor Research and Treatment.2015;3(1):52-55. doi:10.14791/btrt.2015.3.1.52

A 9-month-old male child was brought with complaints of increasing head size for 2 months, increasing lethargy and vomiting for the last 2 days. Radiology revealed a heterogeneously enhancing, globular lesion in the pineal region with hydrocephalus. Near total excision of the tumor was carried out. The histopathological examination of the lesion showed heterogenous elements in the form of mature neuroepithelial and ectomesenchymal tissue. The pathology and radiology of this unusual lesion is discussed with relevant review of literature.
Cartilage ; Child ; Head ; Humans ; Hydrocephalus ; Infant* ; Lethargy ; Male ; Melanins ; Pathology ; Pinealoma ; Vomiting

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Concomitant Subdural Hemorrhage and Intracerebral Hemorrhage due to Brain Metastasis of the Hepatocellular Carcinoma.

Se Youn JANG ; Choong Hyun KIM ; Jin Hwan CHEONG ; Jae Min KIM

Brain Tumor Research and Treatment.2015;3(1):48-51. doi:10.14791/btrt.2015.3.1.48

Hemorrhagic metastatic brain tumors of hepatocellular carcinoma (HCC) are rare and have been mostly presented as intracranial hemorrhage (ICH). A 51-year-old male patient presented with sudden altered level of consciousness. He suffered from HCC since 2010 and transarterial chemoembolization was performed three times for HCC. The brain computed tomography (CT) scans revealed subdural hematoma (SDH) in the right fronto-temporal area and 6.0x3.5 cm sized ICH in the right parieto-occipital lobe. Brain angiographic CT scans demonstrated that the hemorrhagic lesions did not include any enhancing lesions and vascular abnormalities. We undertook a decompressive craniectomy and evacuation of the acute SDH and ICH. During evacuation of ICH, the yellowish mass was observed in the cortical surface of the right occipital lobe. Pathological examination displayed the findings of metastatic brain tumor from HCC. Metastatic brain tumors should be considered in the differential diagnosis as a cause of spontaneous SDH with ICH.
Brain Neoplasms ; Brain* ; Carcinoma, Hepatocellular* ; Cerebral Hemorrhage* ; Consciousness Disorders ; Decompressive Craniectomy ; Diagnosis, Differential ; Hematoma, Subdural* ; Humans ; Intracranial Hemorrhages ; Male ; Middle Aged ; Neoplasm Metastasis* ; Occipital Lobe ; Tomography, X-Ray Computed

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The Clinical Characteristics of Subependymal Giant Cell Astrocytoma: Five Cases.

Tae Young JUNG ; Young Hee KIM ; Shin JUNG ; Hee Jo BAEK ; Kyung Hwa LEE

Brain Tumor Research and Treatment.2015;3(1):44-47. doi:10.14791/btrt.2015.3.1.44

In this study, we reviewed the clinical characteristics of five cases of subependymal giant cell astrocytoma (SEGA) at our hospital between May 1997 and July 2012. The median age was 18 years old (range, 8 to 26). The clinical symptoms were presented as seizure in two patients and headache in three patients. All the tumors were located near the foramen of Monro. The median size of the tumors was 2.5 cm (range, 1.9-4.0). Two patients showed the solitary lesion, and three had subependymal nodules and cortical tubers. The median follow-up duration was 7.4 years (range, 2.0-14.3). Three patients were associated with the tuberous sclerosis complex (TSC). Four patients showed the SEGA at the first presentation and one patient experienced the 1.9 cm-sized growing mass during 7.7 years follow-up after the diagnosis of the TSC. The mass was totally removed in four patients and subtotally in one. Postoperatively, one patient took the medication for the seizure, which was controllable. The subtotally removed mass showed the recurrence postoperative 4.1 years later, and the recurred mass was stable for 4.5 years after the recurrence. The clinical follow-up study of the SEGA showed an indolent behavior before and after the surgery.
Astrocytoma* ; Cerebral Ventricles ; Diagnosis ; Follow-Up Studies ; Headache ; Humans ; Neurosurgery ; Recurrence ; Seizures ; Tuberous Sclerosis

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Thrombosed Large Middle Cerebral Artery Aneurysm Mimicking an Intra-Axial Brain Tumor: Case Report and Review of Literature.

Young Joo KIM ; Sin Soo JEUN ; Jae Hyun PARK

Brain Tumor Research and Treatment.2015;3(1):39-43. doi:10.14791/btrt.2015.3.1.39

This case report presents a fully thrombosed large aneurysm of middle cerebral artery mimicking an intra-axial brain tumor in a 54-year-old male patient. A small mass like lesion was found incidentally in right frontal area. Brain magnetic resonance image showed dark signal intensity on T2-weighted images and peripheral high signal intensity on T1-weighted images with peripheral rim enhancement. We considered intra-axial tumors such as glioma or metastatic tumor as a differential diagnosis. The lesion was approached transcortically, and intraoperatively, the lesion was found to be a large thrombosed aneurysm originating from the lateral lenticulostriate artery of right middle cerebral artery. One vascular clip was applied at the parent artery, and the thrombosed aneurysm was totally removed. There have been many reports of other intracranial lesions wrongly diagnosed as intracranial neoplasms. And thrombosed aneurysms mimicking intracranial neoplasm have been reported in 4 cases previously. According to those case reports, there were no efficient imaging tools to differentiate between these thrombosed aneurysms and intracranial neoplasms. We reviewed those reports and considered about the efficient method to diagnosed accurately before surgery. To sum up, when a patient presents with an intracranial lesion lying on the course of major or distal cerebral arteries, the surgeon should have thrombosed aneurysm in mind as one of the differential diagnosis and be prepared when surgically treating such lesions.
Aneurysm ; Arteries ; Brain ; Brain Neoplasms* ; Cerebral Arteries ; Deception ; Diagnosis, Differential ; Diagnostic Errors ; Glioma ; Humans ; Intracranial Aneurysm* ; Male ; Middle Aged ; Middle Cerebral Artery ; Parents ; Thrombosis

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Primary Diffuse Leptomeningeal Gliosarcomatosis.

Ju Hyung MOON ; Se Hoon KIM ; Eui Hyun KIM ; Seok Gu KANG ; Jong Hee CHANG

Brain Tumor Research and Treatment.2015;3(1):34-38. doi:10.14791/btrt.2015.3.1.34

Primary diffuse leptomeningeal gliomatosis (PDLG) is a rare condition with a fatal outcome, characterized by diffuse infiltration of the leptomeninges by neoplastic glial cells without evidence of primary tumor in the brain or spinal cord parenchyma. In particular, PDLG histologically diagnosed as gliosarcoma is extremely rare, with only 2 cases reported to date. We report a case of primary diffuse leptomeningeal gliosarcomatosis. A 68-year-old man presented with fever, chilling, headache, and a brief episode of mental deterioration. Initial T1-weighted post-contrast brain magnetic resonance imaging (MRI) showed diffuse leptomeningeal enhancement without a definite intraparenchymal lesion. Based on clinical and imaging findings, antiviral treatment was initiated. Despite the treatment, the patient's neurologic symptoms and mental status progressively deteriorated and follow-up MRI showed rapid progression of the disease. A meningeal biopsy revealed gliosarcoma and was conclusive for the diagnosis of primary diffuse leptomeningeal gliosarcomatosis. We suggest the inclusion of PDLG in the potential differential diagnosis of patients who present with nonspecific neurologic symptoms in the presence of leptomeningeal involvement on MRI.
Aged ; Biopsy ; Brain ; Diagnosis ; Diagnosis, Differential ; Fatal Outcome ; Fever ; Follow-Up Studies ; Gliosarcoma ; Headache ; Humans ; Magnetic Resonance Imaging ; Meningeal Carcinomatosis ; Meningoencephalitis ; Neuroglia ; Neurologic Manifestations ; Spinal Cord

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Metastatic Intracranial Hemangiopericytoma to the Spinal Column: A Case Report.

Myung Sung JOO ; Young Joon RHO ; Sang Woo SONG ; Young Cho KOH ; Hong Gee ROH ; So Dug LIM

Brain Tumor Research and Treatment.2016;4(2):128-132. doi:10.14791/btrt.2016.4.2.128

Intracranial hemangiopericytoma (HPC) is a rare brain tumor with aggressive biologic behavior associated with high recurrence rate and often with extracranial metastasis. The most common sites of extracranial metastasis of the intracranial HPC are the long bones, lung, liver and abdominal cavity in the order of frequencies. Extracranial metastases usually occur long after the initial diagnosis of the primary tumor. Metastatic intracranial HPC to the vertebra has been rarely reported. We present a case of intracranial HPC metastasized to the L2 vertebral body 13 years after multiple surgical resections and radiotherapy of the primary intracranial HPC.
Abdominal Cavity ; Brain Neoplasms ; Diagnosis ; Hemangiopericytoma* ; Liver ; Lumbar Vertebrae ; Lung ; Neoplasm Metastasis ; Radiotherapy ; Recurrence ; Spine*

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Failed First Craniotomy and Tumor Removal of Parasagittal Meningioma with Severe Peritumoral Brain Edema.

Youngbo SHIM ; Sang Hyung LEE

Brain Tumor Research and Treatment.2016;4(2):124-127. doi:10.14791/btrt.2016.4.2.124

Parasagittal meningioma often presents as peritumoral brain edema (PTBE). The risk of edema increases when the tumor occludes the superior sagittal sinus (SSS). Although PTBE may be expected based on the patient’s symptoms or radiologic findings, extensive brain swelling and extracranial herniation during elective surgery are rare. Herniation during surgery could lead to irreversible neurological damage and even brain rupture. We report a case of a failed routine craniotomy for a parasagittal meningioma with complete occlusion of the posterior third of the SSS in a 30-year-old male patient. The patient developed extensive brain swelling and extracranial herniation during surgery.
Adult ; Brain Edema* ; Brain* ; Craniotomy* ; Edema ; Humans ; Male ; Meningioma* ; Rupture ; Superior Sagittal Sinus

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