Journal Detail Information

1

Cite

Share

Diagnosis of Gastric Subepithelial Tumor: Focusing on Endoscopic or Radiologic Approach.

The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2015;15(1):17-21. doi:10.7704/kjhugr.2015.15.1.17

Subepithelial tumors (SETs) are occasionally found in the esophagus and stomach during upper endoscopy. Most SETs are asymptomatic and therefore clinically insignificant. However, SETs do have malignant potential, and therefore it is important to distinguish malignant from benign lesions. Among gastric SETs, gastrointestinal stromal cell tumors (GISTs) have malignant potentials that are related to tumor size; however, malignancy can occasionally be found in smaller lesions. Endoscopic ultrasound (EUS) can be used to diagnose GISTs preoperatively, although differential diagnosis on the basis of imaging alone is insufficient. However, when used in combination with EUS-guided fine needle aspiration, diagnostic accuracy increases, although the results can be quite variable. Therefore, we performed endoscopic biopsy of gastric SETs using the endoscopic submucosal dissection (ESD) technique. Our data indicate that deep biopsy via ESD is a safe modality of high diagnostic yield compared with EUS-guided fine needle aspiration in determining the histopathologic features of upper gastrointestinal (GI) SETs, relatively. In addition, pathologic confirmation can be more important than EUS finding. Diagnostic results improve clinical decision making on managing upper GI SETs. It can be recommended that this modality should be considered in upper GI SETs before determining whether tumors should undergo long-term monitoring or surgical resection.
Biopsy ; Biopsy, Fine-Needle ; Decision Making ; Diagnosis* ; Diagnosis, Differential ; Endoscopy ; Esophagus ; Stomach ; Stromal Cells ; Ultrasonography

2

Cite

Share

Diagnosis of Gastric Subepithelial Tumor: Focusing on Endoscopic Ultrasonography.

Eun Young KIM

The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2015;15(1):9-16. doi:10.7704/kjhugr.2015.15.1.9

Gastric subepithelial mass denotes any protruded lesion covered with normal mucosa found during upper gastrointestinal endoscopy or barium study. It can imply various diseases or even impression of normal extraluminal structures. For further evaluation of gastric subepithelial lesion (SEL), endoscopic ultrasonography (EUS) will be the smartest choice. EUS can delineate layered structure of gastric wall and adjacent extraluminal structure making it easy to differentiate extraluminal cause of SEL from intramural lesion. EUS examination of the intramural SEL to look for the origin of the mass, echo characteristics, size, and relationship with the extraluminal structure can assist in an approach to diagnosis. EUS findings can also provide a guide on making therapeutic decisions. When pathologic examination is necessary for a definite diagnosis, EUS-guided tissue sampling is an excellent and safe tool. This article reviewed the diagnosis of gastric subepithelial mass focusing on EUS.
Barium ; Biopsy ; Biopsy, Fine-Needle ; Diagnosis* ; Endoscopy, Gastrointestinal ; Endosonography* ; Mucous Membrane

3

Cite

Share

Natural Course of Gastric Subepithelial Tumor.

Sung Eun KIM ; Moo In PARK

The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2015;15(1):1-8. doi:10.7704/kjhugr.2015.15.1.1

Subepithelial tumor (SET) is a protruding elevated mass covered with normal appearing mucosa, and is a relatively common finding during esophagogastroduodenoscopy. Recently, the incidence of asymptomatic small SETs is increasing due to esophagogastroduodenoscopy for national gastric cancer screening program in Korea. Unfortunately, the management of SETs is still controversial because the natural history of SETs is hardly known. There are only few studies about the natural history of SETs, especially in the stomach. According to studies, the overall rate of increased size of gastric SETs is 5.4~28%. Tumor size, age, non-upper area of the stomach, and detection of anechoic lesion or echogenic foci on endoscopic ultrasound (EUS) are related with size increase in gastric SETs. Gastrointestinal stromal tumors (GISTs) are one of the most important tumors, and the prognosis of GISTs is closely connected with tumor size, mitotic count, and organ location. Among them, tumor size is relatively easy to approach with esophagogastroduodenoscopy or EUS. Asymptomatic gastric SETs < or =2 cm show a benign clinical course and the malignant potential of them is nearly 0%, even if the gastric SETs are confirmed as GISTs. However, asymptomatic gastric SETs >2 cm, < or =5 cm might be considered for detailed pathologic diagnosis and treatment, if the possibility of GISTs cannot be ruled out. Well-designed, prospective studies are required for more accurate management of SETs.
Diagnosis ; Endoscopy, Digestive System ; Gastrointestinal Stromal Tumors ; Incidence ; Korea ; Mass Screening ; Mucous Membrane ; Natural History ; Prognosis ; Stomach ; Stomach Neoplasms ; Ultrasonography

4

Cite

Share

Indications for Helicobacter pylori Eradication Therapy.

So Yoon YOON ; Ki Nam SHIM

The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2012;12(4):213-218. doi:10.7704/kjhugr.2012.12.4.213

Since the discovery of Helicobacter pylori in 1982, it has been recognized as one of the most significant risk factors for gastric cancer and peptic ulcer disease and has been associated with various gastrointestinal disorders. Several sets of guidelines on the treatment indications for H. pylori have been published in many parts of the world. The prevalence of H. pylori is closely related to socioeconomic conditions and varies between the countries, and there are circumscribed indications for H. pylori eradication in high-prevalence regions such as Asian countries, which have higher H. pylori incidence levels than Western countries. However, according to an epidemiological survey conducted in Korea in 2005, the prevalence of H. pylori infection was found to have decreased by up to 59.6%. Hence, it has been suggested that the indications for treatment of H. pylori infection should be expanded. The aim of this review was to identify indications for H. pylori eradication in Korea as compared with other countries and assess the possible future indications for H. pylori eradication.
Asian Continental Ancestry Group ; Helicobacter ; Helicobacter pylori ; Humans ; Incidence ; Korea ; Peptic Ulcer ; Prevalence ; Risk Factors ; Stomach Neoplasms

5

Cite

Share

Jejunal Perforation Caused by Primary Jejunal Diffuse Large B Cell Lymphoma.

Seung Hyun OH ; Hye Seon KANG ; Eun Ok KIM ; Byung Soo JIE ; Hwa Jeong LEE ; Youn Mi SONG ; Jin Seok KIM ; Jung Hwan OH

The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2011;11(3):205-208. doi:10.7704/kjhugr.2011.11.3.205

Small bowel malignancy accounts for approximately 2% of gastrointestinal malignancies. In particular, malignant lymphoma of the small intestine is so rare that it accounts for less than 1% of gastrointestinal malignancies. Initial symptoms are non-specific and diagnosis may be delayed until the patient presents with complications such as intestinal obstruction, hemorrhage, or perforation. A 79-year-old man visited the emergency room with lower abdominal pain. Segmental resection of the small intestine was done and surgery revealed a 9.5x6 cm sized mass with jejunal perforation at 20 cm inferior to the ligament of Treitz. The mass was diagnosed as diffuse large B cell lymphoma. We experienced a case of diffuse large B cell lymphoma which was diagnosed after emergent surgery for jejunal perforation, and report it with a review of literature.
Abdominal Pain ; Aged ; Emergencies ; Hemorrhage ; Humans ; Intestinal Obstruction ; Intestinal Perforation ; Intestine, Small ; Jejunum ; Ligaments ; Lymphoma ; Lymphoma, B-Cell

6

Cite

Share

Gastric Outlet Obstruction by Impacted Phytobezoar at the Normal Duodenal Bulb.

Ami KWON ; Sung Soo KIM ; Kyung Hoon KIM ; Eun Sun KIM ; Hyung Keun KIM ; Young Seok CHO ; Hyun Suk CHAE ; Chang Don LEE

The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2011;11(3):201-204. doi:10.7704/kjhugr.2011.11.3.201

Phytobezoars are the most common bezoars composed of non-digestible food materials, such as fiber, seeds, skin of fruits. The predisposing factors of bezoars are altered gastrointestinal motility and anatomy. It is uncommon for bezoars occurring in patient with normal gastric anatomy to cause impaction on the duodenal bulb. We experienced a phytobezoar at the duodenal bulb causing gastric outlet obstruction in a patient who had no predisposing factors. The patient was treated by endoscopic removal.
Bezoars ; Duodenum ; Fruit ; Gastric Outlet Obstruction ; Gastrointestinal Motility ; Humans ; Seeds ; Skin

7

Cite

Share

A Case of Gastric Lipoma Removed Using a Detachable Snare.

Hye Won KANG ; Ki Nam SHIM ; Kyoung Joo KWON ; Eun Mi SONG ; Ju Young CHOI ; Sung Eun KIM ; Sung Ae JUNG ; Hye Kyung JUNG

The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2011;11(3):198-200. doi:10.7704/kjhugr.2011.11.3.198

Gastrointestinal lipoma is a benign tumor of mature adipose tissue, surrounded by fibrous capsule. They can be located anywhere in the gastrointestinal tract, but rarely in the stomach, especially at the cardia. Gastric lipoma accounts for approximately 2~3% of all benign gastric tumors, and 5% of all gastrointestinal lipomas. Lipoma tends to have very low malignant potential, but if it induces symptoms like abdominal pain or hemorrhage, it needs to be removed. We report a case of gastric lipoma which was successfully removed by only using a detachable snare. A 72-years-old woman who had no specific symptom was found to have a submucosal tumor at cardia. During endoscopy, the fatty internal material accidently came out after tearing the mucosa with biopsy, and it was successfully removed using a detdachable snare.
Abdominal Pain ; Adipose Tissue ; Biopsy ; Cardia ; Endoscopy ; Female ; Gastrointestinal Tract ; Hemorrhage ; Humans ; Lipoma ; Mucous Membrane ; Porphyrins ; SNARE Proteins ; Stomach

8

Cite

Share

Gastrointestinal Stromal Tumor with Accelerated Growth Pattern in the Stomach.

Kyu Re JOO ; Woo Chul CHUNG ; Kang Moon LEE ; Chang Nyol PAIK ; Kyong Hwa JUN ; Hyung Min CHIN

The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2011;11(3):193-197. doi:10.7704/kjhugr.2011.11.3.193

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and can be benign or malignant. To date, there have been no clear standards for the preoperative assessment of GIST malignancy. Currently it is believed that tumors with diameter smaller than 2.0 cm is benign. Herein, we experienced two cases of GISTs that showed an accelerated growth pattern during the follow-up period. In both cases, the tumors were <2.0 cm in size initially and became larger unexpectedly. The resected tumors revealed GIST with intermediate risk and high risk of malignancy according to National Institutes of Health (NIH) consensus symposium.
Consensus ; Follow-Up Studies ; Gastrointestinal Stromal Tumors ; Gastrointestinal Tract ; Mitotic Index ; National Institutes of Health (U.S.) ; Prognosis ; Stomach

9

Cite

Share

Therapeutic Efficacy of Gliptide(R) (Sulglycotide) on Gastritis - A Double Blind, Randomized, Active Drug Comparative, Multi-Center, Phase IV Study.

Kwi Sook CHOI ; Hwoon Yong JUNG ; Jong Jae PARK ; Ki Nam SHIM ; Ho June SONG ; Kee Don CHOI ; Jun Won CHUNG ; Kee Wook JUNG ; Do Hoon KIM ; Jae Dong LEE ; Yang Hee JOO ; Ki Jun SONG

The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2011;11(3):185-192. doi:10.7704/kjhugr.2011.11.3.185

BACKGROUND/AIMS: Sulglycotide is a sulphoglycopeptide isolated from porcine duodenal mucosa. It has antiulcer and cytoprotective activity with anti Helicobacter pylori (H. pylori) effect. This study was performed to assess the therapeutic efficacy and safety of gliptide(R) (sulglycotide) in comparison with another mucosal protective agent, selbex(R) (teprenone) for the treatment of gastritis. MATERIALS AND METHODS: One hundred and twenty one patients with symptomatic erosive gastritis were randomized to receive sulglycotide (gliptide(R)) or teprenone (selbex(R)) for 4 weeks. Improvement and cure rates on endoscopic findings, improvement rates of symptoms, and eradication rates of H. pylori were compared. RESULTS: Of the 121 intention-to-treat (ITT) population, 82 patients comprised the per protocol (PP) analysis. Endoscopic cure rates and improvement rates in the sulglycotide and teprenone group were 36.7% vs. 29.5% and 41.7% vs. 37.7% in ITT and 46.3% vs. 34.2% and 53.7% vs. 43.9% in PP population, respectively. Symptom improvement rates in the sulglycotide and teprenone group were 71.7% vs. 65.6% in ITT and 85.4% vs. 75.6% in PP. Eradication rates of H. pylori were not significantly different between the groups. Results of 95% CIs for the difference in endoscopic cure rate and improvement rate, symptom improvement rate, and eradication rate of H. pylori between the two groups met the criteria for the non-inferiority of sulglycotide to teprenone. No significant adverse events were encountered during the study period. CONCLUSIONS: Gliptide(R) (sulglycotide) is not inferior to selbex(R) (teprenone) in therapeutic efficacy and is a safe and useful therapeutic agent for the treatment of gastritis.
Diterpenes ; Gastritis ; Helicobacter pylori ; Humans ; Mucous Membrane ; Sialoglycoproteins

10

Cite

Share

Intestinal Obstruction due to the Migration of a Phytobezoar during Cola-Lysis in a Patient Who Had Previously Undergone Partial Gastrectomy.

Sun Mee HWANG ; Hae Yon LEE ; Byung Wook KIM ; Jeong Seon JI ; Bo In LEE ; Hwang CHOI

The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2011;11(1):68-70. doi:10.7704/kjhugr.2011.11.1.68

Gastric surgeries may predispose patients to the formation of gastric phytobezoars. Cola-lysis through nasogastric lavage, endosopic infusion and/or the oral intake of cola are recently introduced techniques for the dissolution of phytobezoars. However, their complications have rarely been reported. Herein, we report a 56-year-old woman, who had previously undergone partial gastrectomy, severe intestinal obstruction due to the migration of a phytobezoar during cola-lysis and was successfully managed with surgical intervention.
Bezoars ; Cola ; Female ; Gastrectomy ; Humans ; Intestinal Obstruction ; Middle Aged ; Therapeutic Irrigation

DISPLAY OPTIONS

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share