The Korean Journal of Helicobacter and Upper Gastrointestinal Research  2014;14(1):18-23

doi:10.7704/kjhugr.2014.14.1.18

Complications and Management of Peptic Ulcer Disease.

Chang Seok BANG 1 ; Gwang Ho BAIK

Affiliations

+expand

Keywords

Peptic ulcer hemorrhage; Peptic ulcer perforation; Gastric outlet obstruction

Country

Republic of Korea

Language

Korean

Abstract

Despite the improvement of medical managements of peptic ulcer and decline of Helicobacter pylori infection, complications of peptic ulcer are still prevalent in clinical practice. This is because of the increased use of ulcerogenic medications such as aspirin or non-steroidal anti-inflammatory drug (NSAID) in elderly patients. Peptic ulcer complications include bleeding, perforation, penetration and gastric outlet obstruction. These complications need to be managed by multidisciplinary approaches such as combination of endoscopic treatment, radiologic embolization, or surgical treatments. In addition to using proton pump inhibitors, H. pylori eradication and discontinuing ulcerogenic medications are essential in the prevention of recurrence. Although uncommon, non-H. pylori, non-NSAID ulcers should be suspected as a potential cause in recurrent cases of peptic ulcer complications.