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The application of the new assistance chemotherapy in breast cancer

Chinese Journal of Primary Medicine and Pharmacy.2010;17(22):3072-3073. doi:10.3760/cma.j.issn.1008-6706.2010.22.025

Objective To summarize the application of new assistance chemotherapy(NCT) in the surgeriable breast cancer,to study the security of NCT in the near future curative effects and the influence to surgery way.Methods The clinical date of 36 cases with Ⅰ～Ⅲ breast cancer were retrospectively analyzed. Results There are 8 examples of CCR, 19 examples of CPR,3 examples of PCR in the total cases. The total effective rate is 83.3%.There is no obvious side reaction. Conclusion As a result of the safety and effectiveness, NCT is an important way for treating breast neoplasms.

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Comparison of different internal fixation in treatment of fermoral intertrochanteric fractures in elderly patients

Yongjun HU ; Qi LIANG ; Haiyong CUI ; Bing DONG

Chinese Journal of Primary Medicine and Pharmacy.2010;17(22):3061-3062. doi:10.3760/cma.j.issn.1008-6706.2010.22.019

Objective To compare the therapeutic effect of anatomic plate (AP)and locking compression plate(LCP) in treatment of fermoral intertrochanteric fracture in elderly patients. Methods Nineteen and three patients with fermoral intertrochanteric fracture were treated with anatomic plate (AP) and locking compression plate (LCP). The therapeutic effects were compared in the study. Results All operations were done successfully. Of all cases,72 patients were followed up for 5-24 months. Excellence rate: AP was 66. 7% and LCP was 88. 2%.Conclusions AP had significantly low excellence rate with more complications when compared with LCP. LCP could be the first choice in treatment of fermoral intertrochanteric fractures with high excellence rates and few complications.

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Study on inhibitive effect of polysaccharide of cipangopaludina chinensis gray on hela cells in vitro

Jifeng FU ; Zhongliang JIANG ; Rongbo ZHANG

Chinese Journal of Primary Medicine and Pharmacy.2010;17(22):3057-3058. doi:10.3760/cma.j.issn.1008-6706.2010.22.017

Objective To study the effect of polysaccharide of Cipangopaludina chinensis on gray human cervix cancer cells(Hela cells) in vitro. Methods Polysaccharide of Cipangopaludina chinensis gray was extracted by water extraction. MTT assay and microscope were used to observe its effect on the growth inhibition of Hela cells at different concentrations of the polysaccharide. Results Polysaccharide of Cipangopaludina chinensis could more significantly inhibit the growth of Hela cells. Conclusion Polysaccharide of Cipangopaludina chinensis could inhibit human cervix cancer cells in vitro

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Effect of adefovir combined with thymopeptides α1 in treatment of patients with chronic hepatitis B of positive HBeAg

Zhixin ZHENG

Chinese Journal of Primary Medicine and Pharmacy.2010;17(22):3048-3049. doi:10.3760/cma.j.issn.1008-6706.2010.22.012

Objective To explore the effects of adefovir velocimeter(ADV) combined with Thymopeptides α1 in treatment of patients with chronic hepatitis B (CHB) against hepatitis B virus (HBV). Methods 67 cases of CHB of positive HBeAg were divided into coupling group and single group. 34 cases of coupling group, after being treated for 26 weeks with thymopeptides α1 and ADV,continued to be treated 52 weeks with ADV. 33 cases of single group were treated for 52 weeks with ADV alone. Alanine aminotransferase periodically (ALT), total bilirubin, HBV DNA,HBeAg,anti-HBe were detected at regular intervals. Efficacy were evaluated after finishing the treatment. Results The liver function were both improved obviously in two groups (P ＞ 0. 05). Frequencen of seroconversio of HBeAg/anti-HBe and negative conversion ratio of HBV DNA were much higher in coupling group than that in single group(P ＜ 0. 05). Conclusions The effects were better with Thymopeptides α1 and ADV than that with single ADV. Coupling Thymopeptides α1 and ADV could help to resist and remove HBV.

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Clinical research on conservative treatment and surgical treatment for bronchiectasis

Risheng HUANG ; Zhiyi LIN ; Liangda JIN ; Lixiang ZHANG ; Xiaofeng CHEN ; Shenxian CHEN ; Qiong CHI

Chinese Journal of Primary Medicine and Pharmacy.2010;17(22):3025-3027. doi:10.3760/cma.j.issn.1008-6706.2010.22.001

Objective To compare the curative effect of conservative treatment and surgical treatment for bronchiectasis. Methods 60 patients with bronchiectasis were randomly divided into observation group and control group,30 cases in each group,they were treated with surgery and medical therapy respectively,the clinical efficacy,length of stay, costs, remission time of symptoms and signs, changes of blood gas index and ESR, CRP,TNF-α, WBC,NEUT of the two groups after treatment were compared. Results The curative rate of observation group was significandy higher than control group, while the length of stay, remission time of symptoms and signs and hospitalization costs were significantly lower than control group, the difference was statistically significant (all P ＜0.05) ;After treatmenit,the blood gas index of both groups improved significantly than before treatment(all P ＜ 0.05), and the blood gas index of observation group improved significantly than the control group (all P ＜ 0. 05); After treatment, ESR, CRP,TNF-α,WBC and NEUT of both groups were significantly decreased compared with those before treatment(all P ＜0. 05); Between the two groups, the index value of the observation group decreased significantly (all P ＜ 0.05).Conclusion Surgical treatment for bronchiectasis was superior to conservative treatment with better curative effect,lower cost, shorter hospital stay and faster relief of symptoms and signs, it had good prospects to be applied.

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Comparison of the effect between Jejunostomy with indwelling nasogastric feeding tube in the patients with total gastrectomy

Guodong MA ; Sanrong ZHANG ; Jie PEI

Chinese Journal of Primary Medicine and Pharmacy.2010;17(24):3361-3362. doi:10.3760/cma.j.issn.1008-6706.2010.24.023

Objective To explore the effect of the surgical technique of jejunum fistula and conventional indwelling nasogastric tube with total gastrectomy. Methods The clinical data of 23 advanced gastric cancer patients with total gastrectomy were retrospetively analyzed. Among 23 cases, 17 received jejunum fistual and 6 received indwelling nasogastric. The time to flatus and the ratio of postoperative complications including throat ache, nausea,pneumonia, anastomotic leak were compared. Results Compared with A group, the incidence of disadvantage spit sputum, dyssomnia, throat ache and nausea in B group reduced significantly, the time to flatus was advanced in B group. And other postoperative complications had no difference between two groups. Conclusion Jejunum fistula was rational, safe and effective in patients with total gastrectomy

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Influence of early intervention in calcium and phosphorus metabolism in chronic kidney disease left ventricular hypertrophy

Lei ZENG ; Yojun PANG ; Xinhua PANG ; Shaozhen HUANG

Chinese Journal of Primary Medicine and Pharmacy.2010;17(24):3359-3360. doi:10.3760/cma.j.issn.1008-6706.2010.24.022

Objective To investigate the early intervention to improve calcium and phosphorus metabolism in chronic kidney disease patients left ventricular hypertrophy. Methods 116 cases of non-dialysis patients with chronic kidney disease were randomly divided into 3,4-intervention group and control group, intervention group patients with calcium and phosphorus metabolism in early intervention were observed in patients with calcium, phosphorus, and left ventricular mass index changes. Results Patients in the intervention group after the intervention of phosphorus,calcium and phosphorus product,serum parathyroid hormone were significantly lower than the control group,the difference was all statistically significant (all P＜0.05 );intervention group of LVMI was significantly lower than before the intervention, but also significantly lower than the control group, the difference was statistically significant (P＜0.05). Conclusion Patients with chronic renal calcium and phosphorus metabolism of early intervention can improve symptoms in patients with left ventricular hypertrophy is beneficial to the improvement of patients with the disease.

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Therapeutic effect of naoxintong in treatment of 69 patients with cerebral infarction

Wei LI ; Lixia HU

Chinese Journal of Primary Medicine and Pharmacy.2011;18(1):46-47. doi:10.3760/cma.j.issn.1008-6706.2011.01.021

Objective To observe therapeutic effect of naoxintong on the patients with cerebral infarction.Methods 69 patients with cerebral infarction were randomly allocated to naoxintong group or control group. All patients were treated with 20ml shuxuening injection into veins and aspirin 100mg once a day, and those in naoxintong group were treated with naoxinting moreover. Neurological deficit scores (NDS) were evaluated before and after 1 month and 2 months of treatment Results Effective rate and notable effective rate of naoxintong group after 2 months of treatment were 97% and 88% ,obviously higher than those of control group 79% and 52%. Conclusion Nongxintong treatment for cerebral infarction was effective.

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Clinical study of combination of Chinese and Western medicine in treatment of neonatal jaundice

Xiaodong FENG

Chinese Journal of Primary Medicine and Pharmacy.2010;17(21):2951-2952. doi:10.3760/cma.j.issn.1008-6706.2010.21.035

Objective To observe clinical efficacy of the combination of Chinese and Western medicine in treatment of neonatal jaundice.Methods 86 cases of jaundice in children with jaundice were randomly divided into study group and control group.Two groups of children were treated with TCM and Western medicine treatment of children in this study group was added based on the decoction of Chinese medicine treatment,two courses,the effects and relevant indicators were compared.Results Compared with the control group,the study group had the markedly effective rate and total effective rate was significantly improved,but not markedly lower,there were statistically significant differences(χ2 = 4.67,5.06,all P＜0.05);At the same time,the study group the average daily value of bilirubin decreased markedly,while the time spent doing back jaundice was significantly lower,there were statistically significant difference(t = 2.91,3.91,all P＜0.05).Conclusion Combination of Chinese and Western medicine in treatment of neonatal jaundice disease,could improve clinical syndrome quickly,and had good effect.

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Analysis of surgical treatment on 76 elderly patients with colorectal carcinoma

Jian REN

Chinese Journal of Primary Medicine and Pharmacy.2011;18(1):37-38. doi:10.3760/cma.j.issn.1008-6706.2011.01.017

Objective To study the clinical characteristics in elderly patients with colorectal carcinoma.Methods The clinical dafa of 76 cases of more than 70 years old with colorectal carcinoma were analyzed retrospectively. Results Among 76 elderly patients with colorectal carcinoma,64 cases( 84.2% ) suffered from common diseases in the elderly, such as hypertension, cardiac disease, diabetes ,lung of chronic disease et al. 27 patients had postoperative complications, and 3cases of them died from complications. The rate of postoperative complications in the elderly who had coexistent diseases was 39.1%. Conclusion The elderly patients with colorectal carcinoma frequently had blood hypertension. cardiac disease, diabetes. Strengthening the management of perioperation could improve the security of the operation and decrease the postoperative complications.

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