Journal of Clinical Surgery.2010;18(11):773-775. doi:10.3969/j.issn.1005-6483.2010.11.026
Journal of Clinical Surgery
1993 to Present ISSN: 1005-6483
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Journal of Clinical Surgery.2015;(1):65-67. doi:10.3969/j.issn.1005-6483.2015.01.025
Sentinel lymph node biopsy has been generally accepted as a method for nodal staging in patients with early-stage breast cancer. Patients with negative results of sentinel lymph node biopsy can avoid axillary lymph node dissection and its adverse outcomes. With the development of technology,the in-dications of sentinel lymph node biopsy expand,but its appliance in breast cancer patients with neoadjuvant chemotherapy still remains controversial. This paper reviews the feasibility and timing of sentinel lymph node biopsy for breast cancer patients with neoadjuvant chemotherapy.
Relationship between preoperative fibrinogen and prognosis of patients with colon cancer
Journal of Clinical Surgery.2015;(1):40-43. doi:10.3969/j.issn.1005-6483.2015.01.015
Objective To investigate the prognostic significance of preoperative fibrinogen levels and explore a new prognostic predictor for colon cancer patients. Methods From January 2007 to Decem-ber 2008,the clinical data of colon cancer patients with radical were reviewed retrospectively. Patients were divided into different groups according to BMI,tumor size,stage,differentiation degree,gross type,vascular infiltration,CEA and mGPS score. Differences in preoperative fibrinogen concentration and overall survival were compared between groups. Results A total of 255 patients were enrolled in this study,the mean pre-operative fibrinogen concentration of enrolled patients was(3. 17 ± 0. 88)g/ L. There were significant differ-ences in And preoperative fibrinogen concentration among patients with different tumor size,stage,differen-tiation degree,gross type,vascular infiltration,CEA and mGPS(P < 0. 05). Moreover,result of univariate analysis manifested that the level of preoperative fibrinogen concentration was associated with the overall survival rate. Conclusion Preoperative fibrinogen concentration is associated with the clinicopathologic features of patients with colon cancer,which can serve as a new prognostic marker for prognosis evaluation.
Current status of diagnosis and treatment for medial collateral ligament injury of the knee
Journal of Clinical Surgery.2015;(1):73-76. doi:10.3969/j.issn.1005-6483.2015.01.028
Medial collateral ligament injury is the most common injury of the knee ligament. Most patients with conservative treatment can achieve preinjury activity level. Nonetheless,it's necessary to eval-uate the severity of the injury and judge the best time and details for surgery as serious injury of the medial collateral ligament will cause chronic knee stability and accelerate its degeneration. This paper summarizes the current status of diagnosis and treatment for medial collateral ligament injury of the knee,aiming to pro-vide guidance for dealing with this lesion.
Advances in researches of subacromial impingement syndrome
Journal of Clinical Surgery.2015;(1):70-72. doi:10.3969/j.issn.1005-6483.2015.01.027
Subacromial impingement is an important cause of shoulder pain,which is common in orthopedic diseases. Clinicians have different views on the diagnosis and therapies. This article summarizes research advances of subacromial impingement syndrome in pathogenesis,types,clinical manifestation,ima-ging findings and treatment,hoping to standardize the diagnosis and treatment.
Research progress in microsurgery for talus necrosis
Journal of Clinical Surgery.2015;(5):385-386. doi:10.3969/j.issn.1005-6483.2015.05.025
Talus necrosis is difficult to cure in clinical practice and how to treat it remains con-troversy.Microsurgical methods provide a new path for curing the disease and good curative effects have been achieved according to the literature.This article reviewed microsurgical treatments for talus necrosis in recent years and it may provide references for clinical practice.
Journal of Clinical Surgery.2015;(5):373-375. doi:10.3969/j.issn.1005-6483.2015.05.020
Objective To evaluated clinical effects and effectiveness of dual-port video-assisted thoracic surgery(VATS)for secondary spontaneous pneumothorax.Methods The clinical data of 48 pa-tients with secondary spontaneous pneumothorax who underwent open thoracotomy(n =18)or dual-port VATS(n =30)were reviewed retrospectively.Mean operation time,mean postoperative drainage period and mean postoperative hospital stay between the two groups were compared.Results All surgeries were suc-cessfully performed without reoperation and severe complications.No patient was converted to thoracotomy in the VATS group.There were significant differences in mean operation time [(67.9 ±7.2)min vs (73.3 ±6.4)min],mean postoperative drainage period [(3.2 ±0.9)d vs(5.0 ±1.3)d],and mean postoperative hospital stay [(7.2 ±1.4)d vs(8.7 ±1.5)d]between the dual-port VATS and open thora-cotomy(P <0.05 ).Conclusion Dual-port video-assisted thoracic surgery can reduce postoperative drainage period and postoperative hospital stay and increase satisfaction.It has little influence on upper limb movement and improves postoperative recovery.
Relationship between plasma copeptin level and prognosis in patients with severe acute pancreatitis
Journal of Clinical Surgery.2015;(5):351-353. doi:10.3969/j.issn.1005-6483.2015.05.011
Objective To analyze the relationship between plasma copeptin level and prognosis in patients with severe acute pancreatitis(SAP).Methods The clinical data of 48 SAP patients from January 2010 to October 2014 were collected and another 48 patients who accepted healthexamination dur-ing the same period were selected as controls.Difference in plasma copeptin level was compared between groups.The results of APACHEⅡ,Ranson and modified Marshall scores were also collected to evaluate the severity of disease and the existence of MODS.The prevalence of pancreas and peripancreatic tissues effusion,necrosis,pancreas and peripancreatic abscess,pancreatic pseudocyst and mortality of the experi-mental group were recorded to analyze the relationship among plasma copeptin,complications and mortali-ty.Results The plasma level of copeptin of the experimental group was 0.83 ~5.49ng/ml,with a mean of(3.48 ±1.32)ng/ml;while in the control group,it was 0.09 ~1.46ng/ml,with a mean of(0.23 ± 0.06)ng/ml.There was significant difference between the groups(P <0.05).Patient with a high plasma copeptin level may have a higher risk for local complication,MODS and mortality,and there was significant difference between the groups(P <0.05).A ROC curve identified that a plasma copeptin level >4.02 ng/mL predicted in-hospital mortality of patients,with a sensitivity of 72.7%and a specificity of 81.0%(AUC =0.831,95%CI =1.051 ~1.679,P <0.001).Conclusion SAP patients have elevated levels of plasma copeptin,and higher copeptin levels predict high risks of complications and mortality.
Journal of Clinical Surgery.2015;(5):340-342. doi:10.3969/j.issn.1005-6483.2015.05.007
Objective To determine the interleukin(IL)-17 concentrations in serum and synovi-al fluid from patients with knee osteoarthritis(OA),and evaluate their correlation with disease severity. Methods Serum and synovial fluid were collected from 100 patients with primary knee OA;age-and sex-matched 50 healthy subjects provided serum samples as controls.OA severity and grade were assessed u-sing the Lequesne index and Kellgren and Lawrence(K-L)grading system,respectively.The expression of IL-17 was quantified by enzyme-linked immunosorbent assay.Results Serum IL-17 concentrations were significantly higher in patients than in controls(P <0.05).In the patient group,patients with K-L grade 3 and 4 had higher synovial IL-17 levels than those with K-L grade 2(P <0.05).At the same time,com-pared with K-L grade 3,there was a higher IL-17 level in K-L grade 4 patients(P <0.05).Synovial fluid IL-17 concentration was positively correlated with Lequesne index(r =0.6232,P <0.05).There was no correlation between serum IL-17 concentrations and Lequesne index,however.Conclusion The expres-sion of IL-17 was significantly increased in serum and synovial fluid of knee from patients with knee OA. There was a positive correlation between synovial fluid IL-17 concentrations and OA severity.It suggests that the imbalance of IL-17 expression plays a certain role in the pathogenesis of OA.
Correlation analysis of prostate biopsy and radical prostatectomy specimen
Journal of Clinical Surgery.2017;25(5):392-394. doi:10.3969/j.issn.1005-6483.2017.05.022
Objective To study the reliability of Gleason score by prostate biopsy with prostatic cancer(PCa)in prediction of tumor location and analyse related influencing factors of positive surgical margins after radical prostatectomy.Methods The retrospective study recruited 72 patients with PCa who had been diagnosed by trans rectal ultrasound-guided prostate biopsy,and eventually treated with laparoscopic radical prostatectomy.The correlation of each index were analyzed by statistical software.Results In this study,Kappa test indicated a good agreement that Gleason score between prostate biopsy and radical prostatectomy.Biopsy positive more focused on four peripheral points near the bottom.Biopsy tumor location was not suitable for predicting tumor distribution.Biopsy Gleason score and biopsy positive percentage in biopsy specimen were independent predictors of positive surgical margins.F and L points had good correlation with the positive surgical margins.Conclusion The biopsy Gleason score is a good evidence to pathological grading in patients.These information will lead to positive surgical margins rise possibly:needle biopsy Gleason score exceed 7.25,positive biopsy percentage more than 45% and the location positive biopsy close to prostate apex.
Country
China
Publisher
湖北省医学会湖北分会
ElectronicLinks
http://www.lcwkzz.comEditor-in-chief
whlcwk@126.com
Abbreviation
Journal of Clinical Surgery
Vernacular Journal Title
临床外科杂志
ISSN
1005-6483
EISSN
Year Approved
2008
Current Indexing Status
Currently Indexed
Start Year
1993
Description
历史沿革【现用刊名：临床外科杂志;创刊时间：1993】，期刊荣誉【Caj-cd规范获奖期刊】。
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