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International Journal of Surgery

1974  to  Present  ISSN: 1673-4203

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Function of BMP7 in the genesis and development of colorectal cancer

Zhong REN ; Liqing YAO

International Journal of Surgery.2009;36(12):843-846. doi:10.3760/cma.j.issn.1673-4203.2009.12.020

The family of bone morphogenetic proteins (BMPs) belongs to the superfamily of transforming growth factor-β (TGF-β). It has various functions in the body. In recent years the BMPs family(especially the BMP7) has been discovered to play an important role on the genesis and development of cancer. In this article the characteristic, the mechanism and the function of BMP7 in the genesis and development of cancer are summarized.

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Ultrasound diagnosis on the apophysis lesions of gallbladder

Weiping JIAO ; Ping WANG

International Journal of Surgery.2009;36(12):824-826. doi:10.3760/cma.j.issn.1673-4203.2009.12.013

Objective To discuss the ultrasound diagnosis on the apophysis lesions of the gallbladder. Methods A retrospective analysis was made in 51 cases of polypoid lesions of gallbladder ultrasound char-acteristics of cases, clinical symptoms and pathological types. Results There were 43 cases of benign le-sious (39 cases of cholesterol polyp, 3 cases of adenomyosis, 1 case of inflammatory polyps), 8 cases of tumor lesions (5 cases of adenomatous polyp, 3 cases of malignant tumors). Among those patients with out clinical symptoms (n = 32) were for cholesterol polyps (P < 0. 05) while in, with symptomatic patients (21 cases), 8 were complicated with stone, 4 with ulcerative disease. Three cases (100%) with adenomyosis and 4 cases (80%) with adenomatous polyposis shouwed symptoms (P < 0. 05). Patients with multiple pol-ypoid lesions (22 cases), were benign lesions, and 95.5% were pathologlicdly cholesterol polyp. Seven ca-ses of ultrasound diagnosis of gallbladder polyps were pathologically diagnosed having polyp diameter smaller than 0.3 cm. Ultrasound showed gallbladder wall thickening in 6 cases, 3 with adenomyosis (wall thickness 0. 5 - 1.8 cm), 3 with malignant lesions in gallbladder (wall thickness 0. 5 - 1.2 cm). Conclusions For those patients ultrasound showed asymptomatic or multiple polyps of the gallbladder, cholesterol polyps are the most common type of lesion. Ultrasound is not sensitive to polypoid lesions of the gallbladder with diame-ter less than 0. 3 cm. Those with limited ultrasonic gallbladder wall thickening (>0. 5 cm) should pay more attention to the possibility of having malignant tumors and adenomyosis.

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Prolene hernia system in the tension-free repair operation of inguinal saddle hernia

Ruiwei DAI ; Liping CHEN ; Xu WANG ; Dongxuan LI ; Wenqing LIU ; Jianfeng CUI ; Xiao MA ; Lijun TANG

International Journal of Surgery.2009;36(12):808-810. doi:10.3760/cma.j.issn.1673-4203.2009.12.007

Objective To explore the therapeutic efficacy and operation experience of Prolene Hernia System (PHS) in the tension-free repair operation of inguinal saddle hernia. Methods All 41 cases using PHS were selected as the subjects of this study and the results were analyzed. Results All patients were performed operation under the local anesthesia, and lasted from 25 min to 60 min. They had been keeping in ward for observation from 24 h to 72 h. No serotal swelling, hematoma, and incisional wound infection hap-pened after the operation. The follow-up time had been lasting from 6 months to 42 months, and none of pa-tients catehed a relapse or had the sensation of the foreign bodies. Conclusions Using PHS is safe and ef-fective in the tension-free repair operation, and it is more suited to inguinal saddle hernia. The key of opera-tion success is attaching importance to operation skills.

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Preventive strategy for incisional hernia after selective and emergency laparotomy

Hao LIU

International Journal of Surgery.2009;36(12):829-831. doi:10.3760/cma.j.issn.1673-4203.2009.12.015

Incisional hernia is open a major postoperative complication that abdominal surgery remains. The incision type, suture technique, and the choice of primary suture materials are the main factors affecting wound healing. Prophylactic subfascial non-absorbable mesh can be used in high-risk patients to prevent in-cisional hernia.

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Comparison of retroperitoneal mini-incision and laparoscopic methods in treatment of varicocele

Yonghu SHEN ; Ligui MIN ; Hesuti MA ; Jianjun ZHANG ; Yun SUN ; Bo XIE ; Yong CHU ; Zhuqian WANG ; Qun WU

International Journal of Surgery.2009;36(12):805-807. doi:10.3760/cma.j.issn.1673-4203.2009.12.006

Objective To evaluate the best mean for the treatment of varicocele. Methods The clini-cal effects of the high ligation of spermatic vein under the small incisal opening of the poritneum meta abdom-inal membrane and the ligation of spermatic vein under the laparoscope for the varicocele were retrospectively reviewed. The operating time, the postoperative days and the cost of hospitalization were compared of the two methods. Results Comparing with the group of operation and the group of laparoscope. Among the 158 vat-icocele patients with unilateral or bilateral varicocele, there was not statistical difference in the operating time between the two methods (P > 0. 05), whi]e there was significant difference in the postoperative days and the cost of hospitalization(P <0. 05). Conclusions When the bilateral varicoceles were simultaneously ligated, the high ligation of spermatic vein under the laparoscope was the best selection; if the unilateral varicocele was highly ligated or the patients were unconditional or the patients were not fit for laparoscopic operation, the high ligation of spermatic vein under the small incisal opening of peritoneum was the best operating method.

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Effect of interleukin-22 on cell signaling pathways

Xuanhao LI ; Lindong DU

International Journal of Surgery.2009;36(12):849-852. doi:10.3760/cma.j.issn.1673-4203.2009.12.022

Interleukin-22 (IL-22) is a new kind of eytokine discovered in 2000. The major sources of IL-22 are activated T1 -cells and NK-cells. Tissue cells at outer body barriers, i.e. of the skin, kidney, the di-gestive and respiratory systems all highly express IL-22R or respond to IL-22. IL-22 functions by promoting the anti-microbial defense, inducing phase reactants, protecting against damage and enhancing natural immu-nity. Furthermore, IL-22 mediates the proliferation, differentiation and apoptesis in cancer cells, that gives us a new idea about tumor therapy.

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Human papilloma virus and human breast cancer

Xianghou XIA ; Junchao GU

International Journal of Surgery.2009;36(12):840-842. doi:10.3760/cma.j.issn.1673-4203.2009.12.019

As an increasing threat to women's health worldwide, breast cancer has many well-established risk factors, including genetic suscebility, high concentration of serum estrogen, early-age menarche, late-age menopause and postmenopansal obesity. However, these risk factors only account for about half of the in-cidence of breast cancer. Recent studies provided some clues that three primary hormone responsive virues-human papilloma virus (HPV), mouse mammary tumor virus (MMTV) and Epstein Barr virus (EBV)may act play roles in pathogenesis of human breast cancer. This review aims to have a close look at advances on the potential role, probable mechanism and relating hypothesis of Human papillomavirus in human breast cancer.

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Markers for evaluation of renal dysfunction at early stage

Ning ZHANG ; Qing WANG

International Journal of Surgery.2009;36(12):837-839. doi:10.3760/cma.j.issn.1673-4203.2009.12.018

Cystatin C (Cys C) is used to evaluate the glomerular filtration rate (GFR), renal function and thus reflects changes in endogenous marker. Cys C is not affected by gender, muscle mass, malignancy and its production rate is usually constant, making it one of ideal markes of GFR. This article focuses on clinical application and research of Cys C in a variety of renal diseases, especially in renal dysfunction at an early stage of clinical significance.

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Application of Millikan's modified modality in primary tension-free mesh-plug inguinal herniorrhaphy

Long LIN ; Yijun YANG ; Qingan QIU ; Baochun WANG

International Journal of Surgery.2009;36(12):821-824. doi:10.3760/cma.j.issn.1673-4203.2009.12.012

Objective To summarize the clinical efficacy of Millikan's modified modality using tension-free mesh-plug inguinal herniorrhaphy. Methods A retrospective study was performed in 185 cases with in-guinal hernias. They received surgical treatment using Millikan's modality in our hospital from Jan. 2005 to Dec. 2006. Results There were 184 males and 1 female in these patients with a average age of 47 years ( range 32 - 75 years). Among them, 7 cases had bilateral hernia. The mean operative time of each hernia was 49 min (range 30 -70 min), and the average postoperative hospital stay was 5. 1 days (range 3 - 18 d). The complication rate was 10. 8% (20/185). All patients had no recurrence after following-up over 24 months. Conclusion Millikan's modified mesh-plug hemioplasty is a safe and effective modality in the pri-mary inguinal hernia repair, and has fewer complications and lower recurrence rate.

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Advance in research of CDX2 and CDH17 in gastric cancer

Hailin XI ; Jianhua NIU

International Journal of Surgery.2009;36(12):831-834. doi:10.3760/cma.j.issn.1673-4203.2009.12.016

Caudal-related homeobox transcription factor CDX2 is a specific nuclear transcription factor. It seems to play a key role in intestinal development and differentiation in normal and cancer tissues, and it is important for the maintenance of intestinal epithelium cells, liver-intestine cadherin(CDHIT) as one protein has intimate correlation with invasion and metastasis of tumor, has as well as highly expresses in intestinal-mucosa. Recent studies indicate that CDX2 and CDHI7 is closely associated with tumorigenesis,differentia-tion and metastasis. They might act as a new biomarker of gastric cancer diagnosis and a new target of tumor gene therapy.

Country

China

Publisher

中华医学会;首都医科大学附属北京友谊医院

ElectronicLinks

https://gjwkxzz.yiigle.com/

Editor-in-chief

E-mail

gjwkxzz@163.com

Abbreviation

International Journal of Surgery

Vernacular Journal Title

国际外科学杂志

ISSN

1673-4203

EISSN

Year Approved

2008

Current Indexing Status

Currently Indexed

Start Year

1974

Description

历史沿革【现用刊名:国际外科学杂志;曾用刊名:国外医学.外科学分册;创刊时间:1974】,核心期刊【中文核心期刊(1992)】。

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