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Clinical effect of transumbilical laparoscopic single-site surgery in large hysterectomy

Sufen CUI ; Yan DING ; Ke YU ; Jinjin ZHOU ; Haiyan LIU

Journal of Clinical Medicine in Practice.2023;27(24):93-96. doi:10.7619/jcmp.20232940

Objective To investigate the clinical feasibility,safety and advantages of transum-bilical laparoscopic single-site surgery in large hysterectomy.Methods A total of 82 patients with laparoscopic large hysterectomy were selected as the study objects.Among them,41 patients under-went transumbilical single-hole laparoscopic surgery(single-hole group)and 41 patients underwent traditional multi-hole laparoscopic surgery(multi-hole group).Operation time,intraoperative blood loss,24 h postoperative Visual Analogue Score(VAS),postoperative exhaust time,postoperative morbidity,postoperative hospital stay,cosmetic incision score,postoperative inflammatory index,neutrophil lymphocyte ratio(NLR),incidence of complications and the difference of hemoglobin be-fore and after surgery were compared between the two groups.Results The operation was successful-ly completed in both groups without conversion to laparotomy,and no serious surgical complications occurred.No auxiliary holes were added in the single-hole group.The postoperative exhaust time in the single-hole group was significantly shorter than that in the multi-hole group,the VAS score at 24 h after surgery and NLR at the first day after surgery were significantly lower than those in the multi-hole group,and the aesthetic score of the postoperative incision was significantly higher than that in the multi-hole group(P＜0.05).Conclusion Under the condition of strict control of surgi-cal indications,transumbilical laparoscopic single-site surgery in large hysterectomy has good safety and high feasibility,and has the advantages of fast postoperative exhaust,relieved postoperative pain,light immunosuppression and a incision.

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Precision nursing for patients with visualization technology assisted pulmonary nodule surgery

Yan GAO ; Wei WANG ; Xiaoxin YANG ; Jiefang DING ; Ying YIN

Journal of Clinical Medicine in Practice.2023;27(24):97-100,106. doi:10.7619/jcmp.20233596

Objective To observe the effect of precision nursing based on visualization technolo-gy in treating patients with pulmonary nodule surgery.Methods A total of 186 patients with surgery for pulmonary nodules were randomly divided into control group and observation group,with 93 cases in each group.The control group was given routine nursing,while the observation group was given vi-sualization technology assisted precision nursing on the basis of the control group.The psychological status[the Self-rating Anxiety Scale(SAS)score and the Self-rating Depression Scale(SDS)score]and postoperative recovery[score of the Quality of Recovery Scale with 15 items(QoR-15)]were compared between two groups,and the nursing satisfaction degree was compared between the two groups as well.Results After the intervention,the scores of SAS and SDS in both groups de-creased,and the score of each item in the observation group was significantly lower than that in the control group(P＜0.05);after intervention,the each item of the QoR-15 and the total score in the observation group were significantly higher than those in the control group(P＜0.05);the nursing satisfaction degree of the observation group was 97.8％,which was significantly higher than 89.2％in the control group(P＜0.05).Conclusion Precision nursing based on visualization technology can improve the adverse psychological state of patients with pulmonary nodule surgery,enhance the quality of postoperative recovery,and increase nursing satisfaction degree.

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The effect of attention and interpretation therapy on psychological indicators in patients undergoing postoperative chemotherapy for lung cancer

Wanling GAN ; Chenyan HAN ; Ziming LI ; Ming ZHANG ; Fangfang HAN

Journal of Clinical Medicine in Practice.2023;27(24):101-106. doi:10.7619/jcmp.20232743

Objective To explore the effects of attention and interpretation therapy on psycho-logical resilience,perceived stress and post-traumatic growth for postoperative chemotherapy patients with lung cancer.Methods A total of 100 postoperative lung cancer patients receiving chemotherapy were randomized into control group(n=51)and study group(n=49).The control group implemen-ted conventional psychological guidance,including affective care,psychological comfort and relaxa-tion training;the study group implemented a 10-week attention and interpretation therapy,which mainly included transcendental meditation,emotional coping,gratitude recall,individualizedpsycho-logical guidance,positive thinking training and self-acceptance.The psychological resilience scale(CD-RISC),perceived stress scale(CPSS)and post-traumatic growth inventory(PTGI)scores of the two groups were compared after the intervention.Results After intervention,the scores of all di-mensions and total scores of CD-RISC in two groups were improved compared with those before inter-vention,and were higher in the study group than the control group(P＜0.05).After intervention,the CPSS scores and total scores of two groups were lower than before intervention,and the study group was lower than the control group(P＜0.05).After intervention,PTGI scores in both groups were higher than before intervention,and the study group was higher than the control group(P＜0.05).Conclusion For postoperative chemotherapy patients with lung cancer,the psychological in-tervention of attention and interpretation therapy can effectively alleviate patients'perceptual stress,enhance their psychological resilience status,and improve level of post-traumatic growth.

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Effect of bidirectional traction skin tension reduction technique in treatment of patients with poor healing at position of thoracic drainage tube

Yan ZENG ; Wei ZHANG ; Gang XU ; Xiaowei ZHANG

Journal of Clinical Medicine in Practice.2023;27(24):107-110. doi:10.7619/jcmp.20232659

Objective To explore the effect of bidirectional traction skin tension reduction technique in the treatment of patients with poor healing at position of thoracic drainage tube.Methods A total of 100 patients with poor healing at thoracic drainage tube after thoracoscopic surgery for lung cancer were randomly divided into observation group and control group,with 50 cases in each group.After preparing the wound bed,the control group was treated with traditional dressing change until wound healing,while the observation group was treated with bidirectional traction skin tension reduction technique to close the wound.The wound healing time,the number of dressing change,wound healing quality and satisfaction degree of wound nursing were compared between the two groups.Results Wound healing time and the number of dressing change in the observation group were significantly shorter and less than those in the control group(P＜0.05).At 3 months of wound healing,the score of each item and total score of the Vancouver Scar Scale in the observation group were significantly lower than those in the control group(P＜0.05).The total satisfaction rate of wound healing in the observation group was 94.00％,which was significantly higher than 72.00％in the control group(P＜0.05).Conclusion In the treatment of patients with poor healing at thoracic drainage tube after thoracoscopic surgery for lung cancer,the application of bidirectional traction skin tension reduction technology can promote wound healing,shorten wound healing time,improve wound healing quality,reduce scar hyperplasia,and increase patients'satisfaction degree to wound nursing.

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Influence of whole process case nursing mode on the medical experience of patients undergoing oral surgery

Baohong SHEN ; Huili FAN ; Rongrong WANG

Journal of Clinical Medicine in Practice.2023;27(24):111-114. doi:10.7619/jcmp.20233252

Objective To observe the influence of the whole process case nursing mode on the medical experience of patients undergoing oral surgery.Methods A total of 168 patients with oral surgery were chosen as research objects,and they were randomly divided into control group and obser-vation group,with 84 patients in each group.The control group was given routine nursing care,while the patients in the observation group were given whole process case nursing mode based on on the con-trol group.The medical experience and mental state scale scores in two groups were observed before and after the intervention,and the nursing satisfaction in two groups was analyzed.Results The scores of each dimension and total score of Hospital Consumer Assessment of Healthcare Providers and Systems(HCAHPS)in the observation group were higher than those in the control group(P＜0.05).After intervention,the scores of Dental Fear Scale(DFS)and Dental Anxiety Scale(DAS)in the ob-servation group were lower than those in the control group(P＜0.05).The nursing satisfaction of pa-tients in the observation team was 95.2％,which was higher than 85.7％in the control group(P＜0.05).Conclusion The whole process case nursing mode can improve the medical experience and nursing satisfaction of patients undergoing oral surgery on the basis of routine nursing,and alleviate negative emotions such as anxiety and fear.

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Review of role of copper metabolism in the treatment of cancer

Xinyu ZHANG ; Dan YU ; Ming LIU

Journal of Clinical Medicine in Practice.2023;27(24):115-120. doi:10.7619/jcmp.20231887

Copper is an essential trace element in the human body,which participates in numer-ous cellular mechanisms and signaling pathways,and various biological activities need to be coordina-ted through redox activity of copper.If the amount of copper in the cell exceeds the cell's own needs or is improperly distributed within the cell,the cellular toxicity will occur,and many cancers will be characterized by increasing of copper.Copper can participate in the development and spread of cancer by promoting cell proliferation,angiogenesis,and cell metastasis.Copper chelators and copper ion carriers are effective means of maintaining copper concentration at physiological levels.This paper re-viewed the regulation of copper in cells and the role of copper and copper binding proteins in the oc-currence and development of cancer,and discussed the therapeutic progress of using copper deriva-tives as anticancer agents.

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Research progress on positron emission tomography/magnetic resonance imaging in diagnosis and treatment of breast cancer

Xiaolu LI ; Liqun HUO ; Jun GU

Journal of Clinical Medicine in Practice.2023;27(24):121-125. doi:10.7619/jcmp.20231580

The positron emission tomography/magnetic resonance imaging system(PET/MRI)is currently the latest hybrid imaging method that combines metabolic data with morphological data,pro-viding more comprehensive information in the diagnosis and treatment of breast cancer.This article reviewed the clinical applications of PET/MRI in diagnosis,staging,treatment response evaluation,and prognosis prediction of breast cancer.

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Research progress on the relationship between obstructive sleep apnea and dry eye

Haobin ZHU ; Hongmei YUE ; Xingdong WU ; Miaomiao LIU ; Yating LI ; Jinhui XU

Journal of Clinical Medicine in Practice.2023;27(24):126-131,120. doi:10.7619/jcmp.20232459

Obstructive sleep apnea(OSA)can lead to complications in various systems and or-gans of the body.Dry eye(DE),the most common ocular surface disease in clinical practice,affects visual-related daily activities and work in varying degrees.Recent studies have revealed a potential re-lationship between OSA and DE.OSA can induce DE through a series of mechanisms such as oxidative stress,inflammation,rhythm disorder and so on,and the combination of OSA and DE may profoundly affect the sleep health,mood disorders,and quality of life of patients in a new form overall.However,there is still a lack of systematic understanding of the comorbidity of OSA and DE,resulting in insuffi-cient screening,diagnosis and treatment of OSA related DE in clinical practice.This paper provided a review of the relationship between OSA and DE to raise awareness among clinicians of the diagnosis and management of DE during OSA treatment.

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Clinical application status of T cell immunoglobulin and mucin domain-containing protein 3 and its monoclonal antibody in tumor

Shuyue GAO ; Feiyu ZHAO ; Runjia FAN ; Jiamin CHENG ; Niansong QIAN

Journal of Clinical Medicine in Practice.2023;27(24):132-137. doi:10.7619/jcmp.20232215

T cell immunoglobulin and mucin domain-containing protein 3(Tim-3)is a member of the Tim family,which is widely expressed on the surface of various cells and can be involved in the occurrence and development of diseases such as autoimmune,infection and cancer.Clinical trials have found that a combination of blocking Tim-3 and programmed cell death 1(PD-1)can improve the anti-cancer immune response and regression of tumors in patients with advanced cancer.This arti-cle reviewed the basic biological structure of Tim-3,corresponding ligand and its role in tumor micro-environment,and summarized the ongoing clinical trials of TIM-3.These data suggested that Tim-3 could be used as a potentially significant checkpoint receptor for future anti-tumor therapy,and sum-marized the ongoing clinical trials of drugs,indicating that Tim-3 can be used as a potential check-point receptor for future anti-tumor therapy.

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Research progress in prevention and treatment of coronavirus disease 2019 by traditional Chinese medicine

Wenlei WANG ; Hailin WEI ; Qin SU ; Pinghu ZHANG

Journal of Clinical Medicine in Practice.2023;27(24):138-143,148. doi:10.7619/jcmp.20232364

Since outbreak of the coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)at the end of 2019,hundreds of millions of people were infected and millions of people around the world were killed.SARS-CoV-2 is highly prone to present rapid mutations that can render vaccines ineffective.Drug therapy is currently an effective mean to prevent and treat COVID-19,and traditional Chinese medicine therapy based on clinical char-acteristics and syndrome differentiation has played an extremely important role in the prevention and treatment of COVID-19 in China.Therefore,the characteristics and mechanism of the various prescrip-tions via multiple approaches and targets used in the treatment of COVID-19,including drugs with func-tions of heat-clearing,exterior-resolving,aromatic flavor and damp-resolving,and deficiency-tonifying,based on the clinical experience of Chinese traditional medicine in preventing and treating COVID-19,in order to provide reference for the clinical treatment of such diseases with symptomatic prescriptions.

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