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The Relationship of Obesity and Lifestyle to Health Status among Korean Men in the Health Screen Examinees.

Soonchunhyang Medical Science.2012;18(1):12-20.

OBJECTIVE: This study was conducted to investigate the relationship of obesity and lifestyle to health status among Korean men in the Health Screen Examinees. METHODS: We checked out the results of lifestyle including smoking, alcohol, exercise, regular meals, preference of meat/vegetable, and spicy food which were contained in questionnaire, among 1,890 adult men in the Health Screen Examinees. And we also evaluated the result of body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood sugar (FBS), liver function tests (aspartate aminotransferase, alanine aminotransferase [ALT], gamma-glutamyl transpeptidase [GPT]), and lipid profiles (total cholesterol [TCHO], triglyceride [TG], low density lipoprotein [LDL], high density lipoprotein [HDL]). Statistical analysis of the health profiles and lifestyle, BMI were performed by using multiple logistic regression analysis. RESULTS: On multiple logistic regression analysis, 'obesity' was related to hypertension, diabetes mellitus, liver disease, and dyslipidemia. 'Smoking' was related to TG and HDL. 'Unhealthy drinking' was related to SBP, DBP, hypertension, ALT, gamma-GPT, liver disease, TG, HDL, and dyslipidemia. 'Irregular exercise' was related to FBS, ALT, TG, LDL HDL, and dyslipidemia. 'Irregular meals' were related to TCHO, LDL, and HDL. CONCLUSION: For 1,890 adult men, an obesity and unhealthy lifestyle (smoking, alcohol, irregular exercise and eating meals, and preference of meat and spicy food) were related to hypertension, diabetes mellitus, liver disease, and dyslipidemia. So health promotion is necessary for the patients with hypertension, diabetes mellitus, liver disease, and dyslipidemia to recover from these chronic diseases.
Adult ; Alanine Transaminase ; Blood Glucose ; Blood Pressure ; Body Mass Index ; Cholesterol ; Chronic Disease ; Diabetes Mellitus ; Dyslipidemias ; Eating ; Fasting ; gamma-Glutamyltransferase ; Health Promotion ; Humans ; Hypertension ; Life Style ; Lipoproteins ; Liver Diseases ; Liver Function Tests ; Logistic Models ; Male ; Meals ; Meat ; Obesity ; Surveys and Questionnaires ; Smoke ; Smoking

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Is the Spinous Process of T7 Usually at the Same Level as the Inferior Tips of the Scapulae?.

Mun Gyu KIM ; Si Young OK ; Sang Ho KIM ; Se Jin LEE ; Sun Young PARK ; Eun Hyo KOH ; Heon Yong BAE ; Kyung Yul HUR

Soonchunhyang Medical Science.2012;18(1):9-11.

OBJECTIVE: Appropriate placement of thoracic epidural catheter provides an adequate postoperative analgesia in chest and upper abdominal surgery. Usually, when thoracic epidural puncture is performed, both scapular lower tips and the thoracic (T)7 spinous process is assumed to be at the same horizontal level. The aim of this study is to identify the thoracic epidural puncture in the sitting position, with the neck flexed and arms crossed, may change the relationship between the thoracic vertebrae and the scapular lower tips. METHODS: One hundred patients with postoperative patient controlled epidural analgesia using thoracic epidural catheters were enrolled. It is presumed that the both scapular lower tips and T7 spinous process is at the equal level when performing thoracic epidural puncture. The actual insertion level of the Tuohy needle was examined by radiography when the patient was in the sitting position. RESULTS: Out of 100 patients, there were 62% that were in the same level as the scapular lower tips and T7 spinous process. However, 1% of the patients leveled at T4, 1% at T5, 25% at T6, 18% at T8, and 1% at T9. CONCLUSION: When performing the thoracic epidural puncture under the sitting position, the relationship of the T7 and the scapular lower tips may change. The change of position of scapular lower tips varied among T6.82+/-0.70. Therefore, to be precise, it is advised to utilize C-arm guide when epidural puncture is carried out.
Analgesia ; Analgesia, Epidural ; Arm ; Catheters ; Humans ; Neck ; Needles ; Punctures ; Thoracic Vertebrae ; Thorax

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The Study about the Plans for Consolidating Screening Function of Special Health Examination for Occupational Asthma.

Seong Yong CHO

Soonchunhyang Medical Science.2012;18(1):1-8.

OBJECTIVE: The aim of this study is to consolidate screening function of special health examination for occupational asthma by investigating the results of respiratory function test as for workers who have been exposed to agents that cause occupational asthma. METHODS: To find out cases of occupational asthma, we carried out non-specific bronchial hyperresponsiveness (NSBH) test, peak expiratory flow rate (PEFR) test in appointed order for asthma-suspected cases among 4,602 workers that had a spirometry as a special health examination from April 2009 to July 2011. And we also performed t-test, one-way ANOVA, and multiple regression analysis to compare and analyse the associations between forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) and duration of exposure, kinds of agents, and number of exposed agents that cause occupational asthma. RESULTS: The case of occupational asthma was not found among 4,602 workers. And the result of a multiple regression analysis showed that organic compounds were correlated with FEV1/FVC (P=0.021). However, duration of exposure and number of exposed agents that cause occupational asthma were not associated with FEV1/FVC. CONCLUSION: For strengthening screening function of special health examination for occupational asthma, we can consider simultaneous operation of NSBH and PEFR, extending the PEFR term from 2 weeks to 4 weeks, thorough history taking on asthma. And as organic compounds may have effect on bronchial obstruction, so we need to concentrate on organic compounds-exposed workers for early screening of occupational asthma.
Asthma ; Asthma, Occupational ; Forced Expiratory Volume ; Mass Screening ; Peak Expiratory Flow Rate ; Respiratory Function Tests ; Spirometry ; Vital Capacity

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Successful Treatment of Crizotinib-Associated Severe Hepatotoxicity in Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer.

Joon JIN ; Seo Yeon AHN ; Sunmin KIM ; Ho Sung LEE ; In Jae OH ; Kyu Sik KIM ; Young Chul KIM ; Yoo Duk CHOI

Soonchunhyang Medical Science.2014;20(1):35-38.

Crizotinib-associated severe hepatotoxicity has been rarely reported and experts recommended stopping crizotinib treatment in patients with grade 3/4 transaminase elevation. We experienced a case of anaplastic lymphoma kinase-positive non-small cell lung cancer occurring as a result of severe hepatotoxicity due to crizotinib-associated hepatitis, accompanied by the reactivation of chronic hepatitis B, which was reversed with dose reduction and anti-viral therapy. Our case highlights the possibility that crizotinib might induce hepatitis and this might be associated with the underlying presence of chronic hepatitis B. In addition, crizotinib could be continued with reduced unless there are any other therapeutic options.
Carcinoma, Non-Small-Cell Lung* ; Hepatitis ; Hepatitis B, Chronic ; Humans ; Lymphoma*

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Rosai-Dorfman Disease Combined with Aortic Vasculitis, Arrhythmia, and Valvular Heart Disease.

Shin Il KIM ; Ji Young HAN ; Young Hoon PARK ; Joo Han LIM ; Moon Hee LEE ; Chul Soo KIM ; Hyeon Gyu YI

Soonchunhyang Medical Science.2014;20(1):31-34.

Rosai-Dorfman disease (RDD) is a rare and benign self-limited disorder with pathologic feature of the lymph node sinuses expanded by a proliferation of distinctive histiocytes. The most often involving site is bilateral cervical lymphadenopathy, followed by the skin and soft tissue. Treatment options, including steroid, chemotherapy, radiotherapy and debulking surgery depend on the symptoms or the extent and localization of the lesions. We encountered a very rare case of RDD at the skin lesions, particularly combined with aortic vasculitis, arrhythmia, and valvular heart disease.
Arrhythmias, Cardiac* ; Drug Therapy ; Heart Valve Diseases* ; Histiocytes ; Histiocytosis, Sinus* ; Lymph Nodes ; Lymphatic Diseases ; Methotrexate ; Prednisolone ; Radiotherapy ; Skin ; Vasculitis*

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A Case of Primary Mature Teratoma of the Rectum.

Hyun Sung PARK ; Seung Goun HONG ; Se Young JUNG ; Shin Myung KANG ; Kyoungyong LEE ; Dong Wook YU

Soonchunhyang Medical Science.2014;20(1):27-30.

A mature teratoma is a tumor composed of normal derivatives of all three germ layers, and usually occurs in ovaries, testes, or mediastinum. Mature teratoma of the gastrointestinal tract occurs less frequently, and case reports of primary mature teratoma of the rectum have not been published much. Here, we report a 65-year-old woman patient presented with lower abdominal discomfort. Colonoscopy revealed a pedunculated polypoid tumor arising from the rectum with hairs on its surface, and endoscopic ultrasound revealed an exophytic pattern bulging from the serosa. The tumor was removed surgically and confirmed histologically as a benign, primary mature teratoma of the rectum.
Aged ; Colonoscopy ; Female ; Gastrointestinal Tract ; Germ Layers ; Hair ; Humans ; Mediastinum ; Ovary ; Rectum* ; Serous Membrane ; Teratoma* ; Testis ; Ultrasonography

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Intraoperative Detection of Rate Dependent Left Bundle Branch Block.

Bon Sung KOO ; Mi Soon LEE ; Sung Hwan CHO ; Sang Hyun KIM

Soonchunhyang Medical Science.2014;20(1):24-26.

Rate dependent left bundle branch block (RDLBBB) is an uncommon case. RDLBBB is defined as an intraventricular conduction defect that may return, if only temporarily, to sinus rhythm at lower heart rates. It appears when the heart rate exceeds a certain critical value. Although RDLBBB is usually benign, its diagnosis and treatment have clinical importance for association of RDLBBB and myocardial ischemia and infarction. Therefore, in the case of detection of intraoperative RDLBBB, a clear differentiation should be done as soon as possible. Also it is important to start appropriate treatment and to do clinical follow-up examination. We report a case of intraoperative RDLBBB during general anesthesia for laparoscopic cholecystectomy in 82 years old female patient who has a history of hypertension.
Anesthesia, General ; Bundle-Branch Block* ; Cholecystectomy, Laparoscopic ; Diagnosis ; Electrocardiography ; Female ; Follow-Up Studies ; Heart Rate ; Humans ; Hypertension ; Infarction ; Myocardial Ischemia

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The Effect of alpha-Blocker Treatment for Nocturia with Benign Prostatic Hyperplasia.

Sang Wook LEE ; Changho LEE

Soonchunhyang Medical Science.2014;20(1):18-23.

OBJECTIVE: Nocturia is one of the most bothersome complaints in men with benign prostatic hyperplasia. It might be valuable to determine if alpha-blocker treatment for benigh prostatic hyperplasia can improve nocturia and the quality of life (QoL). The purpose of this study was to determine the efficacy of alpha blocker therapy in benigh prostatic hyperplasia patients with nocturia. METHODS: From January 2004 to June 2006, 68 men (> or =45 years) with lower urinary tract symptoms (LUTS: International Prostatic Symptom Score (IPSS)> or =12) and benign prostatic hyperplasia by transrectal ultrasonography (> or =25 mL) and a maximal urine flow rate (Qmax< or =12) were selected for this study. The efficacy of alpha blocker treatment was assessed by analyzing IPSS, QoL, Qmax, and postvoid residual urine (PVR). The data for these parameters was acquired at baseline and after short-term (range, 4-6 weeks) and long-term (range, 12-14 weeks) treatment. We analyzed the relationships between nocturia and other parameters, including age, prostate volume, Qmax, and PVR after alpha-blocker treatment. RESULTS: Overall, 47 of the 68 patients (69.1%) completed the study. IPSS, QoL, Qmax, and PVR showed significantly improvement after alpha blocker treatment. The nocturia score improved 23.8% after long-term alpha blocker treatment. However, nocturia improvement was lowest among the seven individual symptom scores. Other clinical parameters, including patient age, prostate volume, Qmax, and PVR, were not significantly associated with nocturia; only the LUTS severity was associated with nocturia. CONCLUSION: Treatment with alpha-blocker can reduce nocturia in benigh prostatic hyperplasia patients and can improve QoL.
Adrenergic alpha-Antagonists ; Humans ; Lower Urinary Tract Symptoms ; Male ; Nocturia* ; Prostate ; Prostatic Hyperplasia* ; Quality of Life ; Ultrasonography

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A Single-Center Experience of Transfusion Free Surgical Treatment over 13 Years in Korea.

Jae Hwa YOO ; A Na CHO ; Se Jin LEE ; Wook YOUM

Soonchunhyang Medical Science.2014;20(1):14-17.

OBJECTIVE: Patient' desire of transfusion free surgery has been increasing due to blood transfusion risks. We analyzed the perioperative parameters and perioperative management of transfusion free surgical treatment in Soonchunhyang University Seoul Hospital. METHODS: Operation quantity and blood unstoring count from blood bank between 2000 and 2012 were collected from chronological records. Perioperative parameters including preoperative hemoglobin level, postoperative hemoglobin level, and lowest hemoglobin level were collected from medical records. Perioperative blood management such as acute normovolemic hemodilution, intraoperative blood cell salvage, or hematinic agents and complication were assessed. RESULTS: A total of 3,088 patients underwent transfusion free surgery at Soonchunhyang University Seoul Hospital between 2000 and 2012. Postoperative hemoglobin level <5.0 g/dL were 33 patients. Four patients expired at postoperative period with serious perioperative complications. Average of expired patient's hemoglobin was 3.22 g/dL and overall mortality was 0.12%. Operation was increased as years go by. The amount of blood use bank wasn't increased in general patients with transfusion. CONCLUSION: Careful perioperative blood management for transfusion free surgical treatment was responsible for safety and results in good clinical outcomes. Overall transfusion rate was decreased in spite of increasing operation quantity.
Blood Banks ; Blood Transfusion ; Bloodless Medical and Surgical Procedures ; Hemin ; Hemodilution ; Humans ; Korea ; Medical Records ; Mortality ; Operative Blood Salvage ; Perioperative Care ; Postoperative Period ; Seoul

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Serial Positron Emission Tomography Findings and Neuropsychological Assessments in Limbic Encephalitis.

Tae Eun KIM ; Jeong Ho PARK ; Tae Kyeong LEE ; Ki Bum SUNG ; Sun Ah PARK

Soonchunhyang Medical Science.2014;20(1):7-13.

OBJECTIVE: Limbic encephalitis (LE) is characterized by rapid development of impaired cognitive function, seizure and psychiatric symptoms. Brain 18fluoro labelled deoxyglucose (18FDG)-positron emission tomography (PET) typically showed glucose hypermetabolism in the temporomesial region in the acute stage. Although several studies about brain 18FDG-PET in LE have been reported, serial 18FDG-PET findings during the course of the disease are limited. The purpose of this study is to analyze serial 18FDG-PET findings in LE and to compare them with the results of neuropsychological test. METHODS: We studied prospectively two patients diagnosed as LE using clinical criteria. They underwent serial brain magnetic resonance imaging (MRI) and 18FDG-PET scans. They also received detailed neuropsychological tests. RESULTS: Initial 18FDG-PET presented glucose hypermetabolism in unilateral temporomesial region without obvious abnormalities in brain MRI. Follow-up 18FDG-PET images obtained three month later displayed hypometabolism in both temporomesial region. Correspondingly, neuropsychological studies revealed prominent visuospatial and verbal memory deficits. CONCLUSION: The initial 18FDG-PET was very sensitive in visualizing the disease process compared with MRI and suggesting more markedly functional impairment than structural damage in early stage of LE. This was well correlated with cognitive dysfunction measured by neuropsychological test such as anterograde episodic memory loss involving both verbal and non-verbal materials.
Brain ; Deoxyglucose ; Follow-Up Studies ; Glucose ; Humans ; Limbic Encephalitis* ; Magnetic Resonance Imaging ; Memory Disorders ; Memory, Episodic ; Neuropsychological Tests ; Paraneoplastic Syndromes ; Positron-Emission Tomography* ; Prospective Studies ; Seizures

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