Subcutaneous Panniculitis Like T Cell Lymphoma Initially Misdiagnosed as Behcet's Disease.
Journal of Rheumatic Diseases.2013;20(4):275-276. doi:10.4078/jrd.2013.20.4.275
Journal of Rheumatic Diseases
1994 to Present ISSN: 2093-940X
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Journal of Rheumatic Diseases.2013;20(4):270-274. doi:10.4078/jrd.2013.20.4.270
Although tumor necrosis factor (TNF)-alpha antagonist is a successful treatment modality for various autoimmune diseases, including rheumatoid arthritis (RA), ankylosing spondylitis and psoriatic arthritis, many adverse effects have been reported. Cutaneous adverse reactions of TNF-alpha antagonist include skin rash, urticaria, lupus like rash, seborrheic dermatitis and different kinds of psoriasiform dermatitis. We report a case of psoriasiform dermatitis during TNF-alpha antagonist treatment in a 50-year-old woman with RA. The patient has been treated with adalimumab. After 2 months, she developed pruritic erythematous eruption and desquamative lesions on the head and limbs, which were defined as psoriasiform change by a skin biopsy. These skin lesions are successfully treated with combination therapy, including cessation of adalimumab, corticosteroid and phototherapy.
Antibodies, Monoclonal, Humanized ; Arthritis, Rheumatoid ; Autoimmune Diseases ; Biopsy ; Dermatitis ; Dermatitis, Seborrheic ; Exanthema ; Extremities ; Female ; Head ; Humans ; Middle Aged ; Phototherapy ; Skin ; Tumor Necrosis Factor-alpha ; Urticaria ; Adalimumab
Antibodies, Monoclonal, Humanized ; Arthritis, Rheumatoid ; Autoimmune Diseases ; Biopsy ; Dermatitis ; Dermatitis, Seborrheic ; Exanthema ; Extremities ; Female ; Head ; Humans ; Middle Aged ; Phototherapy ; Skin ; Tumor Necrosis Factor-alpha ; Urticaria ; Adalimumab
Partial Anomalous Pulmonary Venous Return (PAPVR) in a Patient with Sjogren's Syndrome.
Journal of Rheumatic Diseases.2013;20(4):266-269. doi:10.4078/jrd.2013.20.4.266
Pulmonary hypertension (PH) is a rare manifestation in patients with primary Sjogren's syndrome (pSS) and it can occur with or without interstitial lung disease (ILD). Patients with PH and ILD who show signs of exacerbation of dyspnea are commonly assessed for pure PH aggravation, ILD progression or pulmonary infection. However, the presence of congenital cardiac anomalies, such as partial anomalous pulmonary vein return (PAPVR), can also be a cause of dyspnea exacerbation. PAPVR is a rare congenital anomaly that involves drainage of 1 to 3 pulmonary veins into the right-sided heart circulation, resulting in a partial left-to-right shunt. Here we present a case of PAPVR as the cause of PH aggravation in a patient with pSS with accompanying PH.
Dyspnea ; Heart ; Humans ; Hypertension, Pulmonary ; Lung Diseases, Interstitial ; Pulmonary Veins ; Sjogren's Syndrome
Dyspnea ; Heart ; Humans ; Hypertension, Pulmonary ; Lung Diseases, Interstitial ; Pulmonary Veins ; Sjogren's Syndrome
A Case of Behcet's Disease Complicated by IgA Nephropathy.
Journal of Rheumatic Diseases.2013;20(4):261-265. doi:10.4078/jrd.2013.20.4.261
Behcet's disease (BD) is a rare, multisystemic disorder characterized by vasculitis. Although renal involvement rarely coexists with BD, several types of renal involvements have been reported: amyloidosis, glomerulonephritis and vascular involvement. Herein, we report a rare case of BD complicated with IgA nephropathy (IgAN). A 42-year-old woman visited the hospital due to joint pains and painful subcutaneous nodules. Based on her medical history of recurrent orogenital ulcers, arthritis, enteral ulcers, erythema nodosum-like skin lesions, and a positive pathergy test, we diagnosed her with BD. To evaluate proteinuria, we performed a renal biopsy. The patient was diagnosed with BD complicated with IgAN, and treated with a low dosage of steroid, colchicine, as well as angiotensin II type I receptor blockers. Although renal involvement in BD is rare, it is important to periodically perform renal function assessments in patients with BD involving abnormal urine results.
Adult ; Angiotensin II Type 1 Receptor Blockers ; Arthralgia ; Arthritis ; Biopsy ; Colchicine ; Erythema Nodosum ; Female ; Glomerulonephritis ; Glomerulonephritis, IGA ; Humans ; Immunoglobulin A ; Proteinuria ; Skin ; Ulcer ; Vasculitis
Adult ; Angiotensin II Type 1 Receptor Blockers ; Arthralgia ; Arthritis ; Biopsy ; Colchicine ; Erythema Nodosum ; Female ; Glomerulonephritis ; Glomerulonephritis, IGA ; Humans ; Immunoglobulin A ; Proteinuria ; Skin ; Ulcer ; Vasculitis
Localized Gastrocnemius Myositis in Crohn's Disease.
Journal of Rheumatic Diseases.2013;20(4):256-260. doi:10.4078/jrd.2013.20.4.256
We describe a case of localized gastrocnemius myositis which developed with flare-up of Crohn's disease. A 21-year old male patient with an 8-year history of Crohn's disease presented with pain and tenderness in both calves without recent abdominal symptoms. Electromyography and gastrocnemius muscle biopsy revealed evidence of inflammatory myositis. Magnetic resonance imaging (MRI) showed bilateral symmetrical diffuse increased signal intensity in T2 weighted images in both gastrocnemius muscles and patchy contrast enhancement. Subsequent gastrointestinal investigation revealed active inflammation of colon with multiple pseudopolyps and enteroenteric fistula on which we commenced oral prednisolone of 30 mg daily. His pain on both calves was improved and muscle enzymes became normal. Following dose reduction of prednisolone, azathioprine 50 mg daily was started considering the patient's active Crohn's disease on endoscopic findings prior to the development of overt abdominal symptoms. This is the first case report of localized gastrocnemius myositis associated with Crohn's disease described in Korea. Calf myositis responded to corticosteroid well and did not recur with maintenance therapy using azathioprine and mesalazine.
Azathioprine ; Biopsy ; Colon ; Crohn Disease ; Electromyography ; Fistula ; Humans ; Inflammation ; Inflammatory Bowel Diseases ; Korea ; Magnetic Resonance Imaging ; Male ; Mesalamine ; Muscle, Skeletal ; Muscles ; Myositis ; Prednisolone
Azathioprine ; Biopsy ; Colon ; Crohn Disease ; Electromyography ; Fistula ; Humans ; Inflammation ; Inflammatory Bowel Diseases ; Korea ; Magnetic Resonance Imaging ; Male ; Mesalamine ; Muscle, Skeletal ; Muscles ; Myositis ; Prednisolone
Journal of Rheumatic Diseases.2013;20(4):251-255. doi:10.4078/jrd.2013.20.4.251
An overlap syndrome is a combination of major features of more than one connective tissue diseases which is presented in the same patient. An overlap syndrome of rheumatoid arthritis (RA) and polymyositis (PM) which involved the upper pharyngeal muscle has not been reported in Korea. Herein, we report a rare case of a patient with a long-history RA presenting proximal muscle weakness and swallowing difficulty, who was successfully treated with a high-dose of corticosteroid, azathioprine and tacrolimus.
Arthritis, Rheumatoid ; Azathioprine ; Connective Tissue Diseases ; Deglutition ; Humans ; Korea ; Muscle Weakness ; Pharyngeal Muscles ; Polymyositis ; Tacrolimus
Arthritis, Rheumatoid ; Azathioprine ; Connective Tissue Diseases ; Deglutition ; Humans ; Korea ; Muscle Weakness ; Pharyngeal Muscles ; Polymyositis ; Tacrolimus
A Case of Acroosteolysis in Primary Hypertrophic Osteoarthropathy.
Journal of Rheumatic Diseases.2013;20(4):247-250. doi:10.4078/jrd.2013.20.4.247
Primary hypertrophic osteoarthropathy or pachydermoperiostosis is a rare hereditary disorder characterized by digital clubbing, pachydermia and periostosis. Its precise incidence and prevalence is still unknown due to the lack of controlled data. It occurs without any underlying causes and usually has a chronic course. Life expectancy may be of normal standards, but many patients develop multiple functional and cosmetic complications. So, it is important to diagnose this disease at an early stage and to treat the symptomat for the quality of life. We report a case of primary hypertrophic osteoarthropathy in a 68-year-old male with clinical features such as digital clubbing and pachydermia, radiographic findings of acroosteolysis and periosteal new bone formation.
Acro-Osteolysis ; Aged ; Humans ; Incidence ; Life Expectancy ; Male ; Osteoarthropathy, Primary Hypertrophic ; Quality of Life
Acro-Osteolysis ; Aged ; Humans ; Incidence ; Life Expectancy ; Male ; Osteoarthropathy, Primary Hypertrophic ; Quality of Life
A Case of Palmoplantar Pustulosis Present in the Daughter of a SAPHO Syndrome Patient.
Journal of Rheumatic Diseases.2015;22(2):127-131. doi:10.4078/jrd.2015.22.2.127
SAPHO syndrome is a rare inflammatory, pseudoinfectious disease. Initially it was an acronym for Syndrome Acne Pustulosis Hyperostosis Osteitis, and the meaning of S was later changed to synovitis. It occurs predominantly in children and adults and is not common over 60 years. The most common clinical presentation is osteoarticular involvement at the anterior chest wall and skin manifestations may be evident, but it could occur years earlier or develop later. We report on two cases of mother and daughter. A 51-year-old female was diagnosed with SAPHO syndrome with costochondritis and palmoplantar pustulosis. Five years later, her 31-year-old daughter presented with similar skin manifestations of the hand and foot.
Acne Vulgaris ; Acquired Hyperostosis Syndrome* ; Adult ; Child ; Female ; Foot ; Hand ; Humans ; Hyperostosis ; Middle Aged ; Mothers ; Nuclear Family* ; Osteitis ; Psoriasis ; Skin Manifestations ; Synovitis ; Thoracic Wall
Acne Vulgaris ; Acquired Hyperostosis Syndrome* ; Adult ; Child ; Female ; Foot ; Hand ; Humans ; Hyperostosis ; Middle Aged ; Mothers ; Nuclear Family* ; Osteitis ; Psoriasis ; Skin Manifestations ; Synovitis ; Thoracic Wall
Journal of Rheumatic Diseases.2015;22(2):123-126. doi:10.4078/jrd.2015.22.2.123
Retroperitoneal fibrosis (RPF) is a rare, progressive disease characterized by chronic non specific inflammation of the retroperitoneum. Although the pathogenesis of idiopathic retroperitoneal fibrosis (IRF) remains unclear, IRF has been reported in association with autoimmune disorders. However, few cases of IRF associated with rheumatoid arthritis (RA) have been reported. We experienced a rare case of IRF in a patient with RA and chronic B viral hepatitis. A 39-year-old Korean man with RA and hepatitis B was referred to our hospital due to left hydronephrosis. An abdominal computed tomography (CT) scan and magnetic resonance imaging (MRI) showed a diffuse infiltrating retroperitoneal mass around the abdominal aorta and left ureter. The patient underwent intraureteral stent insertion and was treated with corticosteroid. Three months later, the follow up abdominal CT showed that the retroperitoneal mass had decreased in size. Herein, we report the first case of coexistent IRF, RA, and chronic B viral hepatitis with a literature review.
Adult ; Aorta, Abdominal ; Arthritis, Rheumatoid* ; Follow-Up Studies ; Hepatitis B ; Hepatitis B, Chronic ; Hepatitis* ; Humans ; Hydronephrosis ; Inflammation ; Magnetic Resonance Imaging ; Retroperitoneal Fibrosis* ; Stents ; Tomography, X-Ray Computed ; Ureter
Adult ; Aorta, Abdominal ; Arthritis, Rheumatoid* ; Follow-Up Studies ; Hepatitis B ; Hepatitis B, Chronic ; Hepatitis* ; Humans ; Hydronephrosis ; Inflammation ; Magnetic Resonance Imaging ; Retroperitoneal Fibrosis* ; Stents ; Tomography, X-Ray Computed ; Ureter
A Case of Thymic Carcinoma with Behcet's Disease Combined with Immunoglobulin A Nephropathy.
Journal of Rheumatic Diseases.2015;22(2):118-122. doi:10.4078/jrd.2015.22.2.118
Behcet's disease is a systemic inflammatory disorder of unknown etiology, characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. Renal involvement is rare in patients with Behcet's disease particularly immunoglobulin A (IgA) nephropathy. Other autoimmune diseases have been associated with increased risk of malignancy, but not Behcet's disease. Some cases of Behcet's disease accompanied by bladder cancer, thyroid cancer, stomach cancer, or hematologic malignancies have been reported. However, to the best of our knowledge, co-occurrence of Behcet's diseases with thymic carcinoma has not yet been reported. We experienced a 49-year-old male patient who had been treated for Behcet disease and IgA nephropathy, who presented with a large mediastinal mass on chest x-ray. After thymectomy, he was diagnosed with thymic carcinoma with complete resection.
Autoimmune Diseases ; Behcet Syndrome ; Glomerulonephritis, IGA* ; Hematologic Neoplasms ; Humans ; Immunoglobulin A ; Male ; Middle Aged ; Skin ; Stomach Neoplasms ; Stomatitis, Aphthous ; Thorax ; Thymectomy ; Thymoma* ; Thyroid Neoplasms ; Ulcer ; Urinary Bladder Neoplasms ; Uveitis
Autoimmune Diseases ; Behcet Syndrome ; Glomerulonephritis, IGA* ; Hematologic Neoplasms ; Humans ; Immunoglobulin A ; Male ; Middle Aged ; Skin ; Stomach Neoplasms ; Stomatitis, Aphthous ; Thorax ; Thymectomy ; Thymoma* ; Thyroid Neoplasms ; Ulcer ; Urinary Bladder Neoplasms ; Uveitis
Country
Republic of Korea
Publisher
Korean College of Rheumatology
ElectronicLinks
http://www.jrd.or.kr/Editor-in-chief
Jae-Bum Jun
rheumatism1@korea.com
Abbreviation
J Rheum Dis
Vernacular Journal Title
ISSN
2093-940X
EISSN
2233-4718
Year Approved
2009
Current Indexing Status
Currently Indexed
Start Year
1994
Description
The Journal of Rheumatic Diseases (JRD) is an official journal of the Korean College of Rheumatology published in both Korean and English. This journal's title has been changed from "The Journal of the Korean Rheumatism Association" in 1994 ~2010. This journal covers all aspects of rheumatic and musculoskeletal diseases and publishes peer-reviewed articles. JRD is published by Medrang, and is available online via http://www.rheum.or.kr. Both clinical and basic researches are welcome, as are new findings on the epidemiology, pathogenesis, diagnosis, treatment, and prevention of diseases
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