Journal of Rheumatic Diseases  2016;23(2):130-135

doi:10.4078/jrd.2016.23.2.130

Discovery of Splenic Sarcoidosis Concurrent with the Diagnosis of Ovarian Cancer: A Case Report.

Eun Heui KIM 1 ; Seung Geun LEE ; Ki Hyung KIM ; Young Mi SEOL ; Eun Kyoung PARK ; Dong Wan KOO ; Na Kyoung HWANG ; In Sub HAN ; Moon Won LEE ; Sung Yong HAN ; Geun Tae KIM ; Hee Sang TAG

Affiliations

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Keywords

Sarcoidosis; Ovarian neoplasms, Granuloma; Granuloma; Positron-emission tomography

Country

Republic of Korea

Language

English

Abstract

Sarcoidosis is a multisystem inflammatory disease of unknown etiology characterized by noncaseating epithelioid granuloma formation. Although the relationship between sarcoidosis and malignancy has been noted in recent decades, there are few case reports describing the concurrent diagnosis of sarcoidosis and malignancy. Herein, we describe a case of biopsy-proven splenic sarcoidosis mimicking metastasis at the time of ovarian adenocarcinoma. Imaging studies including positron-emission tomography-computed tomography were not useful for differentiating sarcoidosis from malignancy. Thus, our case highlights the importance of histopathological examination to rule out nonmalignant conditions before the diagnosis of metastatic disease is made.