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Nutritional therapy in chronic renal failure

Journal of Medical Research.1998;7(3):47-49.

The selective low protein dietary in treatment of chronic renal failure aims at objectives in cluding reduction of symptom of hyperuremia and protection of function of rest normal kidney. However, the limitation of daily protein need will lead to lack of essential aminoacide. Use of ketoacid corresponding with aminoacid reduces the nitrogen supply, prevents the bad progress of chronic renal failure and limits the excessive filtration of glomerular, hyperphosphatemia and secondary increased para- thyroid function.
Kidney Failure, Chronic ; diet therapy

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The fourth bronchial pouch fistula and analysis of 20 cases

Ky Minh Le

Journal of Medical Research.2000;13(3):3-8.

The fourth bronchial pouch fistulae is the lesion of the fourth bronchial-pharyngeal duct in development of the embryo. 20 cases of this disease were diagnosed, operated and followed-up in the institute of ENT, from 1995 to 1997. 11 females and 9 males were affected; It manifested itself by recurrent episodes neck abscess, especially on the left side (95%). 13 fistulous tracts were found on operation with 86% of retrocartilaginous course.
Bronchial Fistula ; Pouchitis

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The role of transbronchial fine needle aspiration in the diagnosis of submucosal bronchogenic carcinoma

Thai Hong Hoang

Journal of Medical Research.2002;18(2):7-12.

Transbronchial needle aspiration in the diagnosis of submucosal bronchogenic carcinoma. Although exophytic endobronchial lesions can readily be diagnosed by forceps biopsy through the rigid bronchoscope. The lesion of submucosal or peribronchial by forceps biopsy difficult to diagnose by biopsy. The utility of transbronchial fine needle aspiration through rigid bronchoscope was made in 98 patients presenting with endoscopic abnormalities suggestive of submucosal bronchigenic carcinoma of respiratory department of Bachmai hospital from 3/1991 to 7/1996. Forceps biopsy was positive in 48 patients (58.77%). Transbronchial needle aspiration was positive in 88 patients (88.79%) and detected 6 cases additional carcinomas (who were treated by anti-tuberculosis of the lung). We concluded that TBNA significantly increases the yield, more effective than forceps biopsy alone in the detection of the infiltration of submucosal bronchogenic carcinoma.
suction ; neoplasms

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Immunohistochemical study of primary extranodal malignant non-Hodgkin's lymphoma

Hong Van Nguyen

Journal of Medical Research.2000;13(3):20-23.

Between 1996 and 1998, 31 cases of primary extranodal malignant non-Hodgkin's lymphoma were studied immunohistochemically. Immunohistochemical study showed that the majority of the cases were of B-cell type: 19 cases (73.07%) and only 3 cases (11.53%) were of the T-cell type. According to the Working Formulation system, the most common histologic type was diffuse, large cell type (61.29%). The histologic grade was moderate grade: 23 cases (74.19%), high grades: 5 cases (16.13%).
Immunohistochemistry ; Lymphoma, Non-Hodgkin

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Mobilization with granulocyte \ufffd?colony stimulating factor (G-CSF) and collection peripheral blood CD34 cells from healthy volunteer for allograft

Tung Quang Nguyen ; Tri Anh Nguyen ; Phan Trung Do

Journal of Medical Research.2007;47(1):13-19.

Background: Peripheral blood stem cells are today the mains source of cells for transplantation. The number of CD34 in peripheral blood of adult healthy volunteers is very low, so we have to mobilize. Objectives: To apply a protocol to collect CD4 cells in peripheral blood of normal donors mobilized by using G-CSF. Subjects and method: G-CSF (Leukokin) at a dose 10 mcg/kg/day was injected subcutaneously in 5 consecutive days for mobilization CD34 from 5 healthy donors. Count the number of CD34 everyday and collect CD34 cells in 5th \ufffd?6th day by automated blood cell separator (COBE-Spectra), observed clinical and hematilogy, biochemistry symtoms spontaneously. Results: The number of CD34 harvested is 215,5 \ufffd?570,2 x 106 CD34/donor. Almost other of parameters of hematology and biochemistry of donors were normal after one week from the last separation. Conclusion: Mobilization with G-CSF and aphaeresis of periphral blood stem cell from normal donors is feasibility and safety. The number of CD34 can be to allograft for an adult patient.
Hematopoietic Stem Cells ; Granulocyte Colony-Stimulating Factor ;

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The preliminary report of occult HBV infection in Vietnamese

Truong Xuan Bui ; Bang Van Nguyen ; Phuong Minh Tran ; Trach Khanh Nguyen ; Quy Tran ; Yoshihiko Yano ; Yasushi Seo ; Yoshitake Hayashi

Journal of Medical Research.2007;47(1):28-32.

Background: Vietnam is located in the endemic region of hepatitis B virus (HBV) infection, but no data of occult HBV infection was reported at present. Objectives: To investigate the prevalence of occult HBV infection in different ethnics of people and generations. Subjects and method: 80 voluteers with HbsAg negative from five different ethnics: Kinh, Tay, Mong, Giay and Dao in a Chino \ufffd?Vietnamses border province (Lao Cai) were enrolled in the study. After HBV-DNA was extracted, nested PCR of S gene and of Core-promoter/Pre-core region were used to detect HBV-DNA. Specifying nucleotide sequence was confirmed by direct sequencing. Results:The prevalence of occult HBV infection in population study was very high 73/80 (91,3%) by nested PCR of Core-promoter/Pre-core, significantly more sensitive than nested PCR of S gene (26,3%) (p<0,0001). The prevalence of occult HBV infection was notdifferent between ethnics of people or between children, adults. Conclusion: Occult HBV infection in Vietnamese is very common; however, nationwide further studies should be carried out to confirm this preliminary results and evaluate the impact of occult HBV infection in Vietnam.
Hepatitis B virus ; Hepatitis B Surface Antigens ;

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Intubation condition and side effects of different doses of succinylcholine

Thu Thi Minh Nguyen ; Tu Huu Nguyen

Journal of Medical Research.2007;47(1):44-49.

Background: Succinylcholine is drug muscle relaxant the only depolarizing current can also be used in clinical. Objectives: The current study assessed the intubation condition and side effects of different doses of succinylcholine. Subjects and method: In a randomized, double blind trial, 90 patients were divided into 3 groups. 1, 1.5 or 2 mg/kg succinylcholine was added with Fentanyl and Thiopental for induction in group I, II and III, respectively. A rapid induction and postoperative myalgia were evaluated. Results: Fasciculation time as well as myalgia increased significantly by the doses. Intubation conditions were better in group II and III. Increase of kalemia was seen in all groups, but most significantly in group III (3,7 \xb1 0,3 vs 3,3 \xb1 0,2, p<0,05). Conclusion: 1, 1.5 or 2 mg/kg succinylcholine equally provided acceptable intubation condition. Succinylcholine 2 mg/kg induced more fasciculation, myalgia and increase of kalemia.
Succinylcholine/ adverse effects ; Intubation ;

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Treatment of Hodgkin\u2019s disease with ABVD followed by low-dose involved field of radiotherapy: analysis of efficacy

Mai Tuyet Nguyen ; Duc Ba Nguyen

Journal of Medical Research.2007;47(1):60-64.

Background: Treatment of Hodgkin\u2019s disease with ABVD followed by low-dose involved field of radiotherapy is currently considered the standard of care. Objectives: This study was evaluated the efficacy and some pronogstic factors. Subjects and method: 103 consecutive patients with newly diagnosed HD\ufffd?disease treated with combination CT and RT at K-hospital between 10/2001 \ufffd?3/2005 were eligible. The end points of the study were complete response (CR), relapse-free survival (RFS), overall survival (OS). Tests were used for analysis: chi-square test, Kaplan-Meier method... Results: 103 patients (100%) achieved a CR. The RFS and OS rate at 5 years were 64,6% and 91,7%. Pronogstic factors are sex, anemia, B symtom, liver lesion. Conclusion: Treatment plan has brought the most effective so far. Liver damage is a bad influence markedly the survival time.
Hodgkin Disease/ radiotherapy ;

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Evaluation of vitrectomy for severe penetrating eye injury in children

Yen Thi Thu Nguyen

Journal of Medical Research.2007;47(1):73-77.

Background: Severe penetrating eye injury is a common emergency in ophthalmology. Objectives: The evaluation results and complications following vitrectomy in severe penetrating injury in children. Subjects and method: This study included 136 eyes with penetrating eye injury, who were treated at the Trauma department of National Institute of Ophthalmology, Hanoi \ufffd?Vietnam from 1999-2000. Vitrectomy was performed through the limbal and pars plana in 135 patients, 105 boys and 30 girls. Results: Remove intraocular foreign body: 11%, procedure for retinal detachments: 14%. The common functional success (visual acuity of 5/2000 or better) rate was 55,1%. Functional success: absent retinal detachment: 60,7%; present: 21,1%. Anatomic success rate was 66,2%. 4 eyes (2,9%) were eviscerated. Complications of the surgery were: iridocyclite, edema of the cornea, hemorrhage, hyphema. Conclusion:Vitrectomy techniques showed its good effect in treating penetrating eye injury in children. Presence retinal damage and endophthalmitis have significant effect on the final visual outcomes.
Eye Injuries ; Penetrating/ surgery ; Vitrectomy ; Child ;

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Primary study on hepatoprotective effect of curcuminoid in mice

Thanh Ngoc Vu ; Mai Thi Tuyet Vu

Journal of Medical Research.2007;47(2):22-28.

Background: Curcuminoid in crocus has a wide spectrum of therapeutic effects such as antitumor and anti-inflammatory effects, including antibacterial, antiviral, antifungal, and antispasmodic activities. Curcuminoid \ufffd?biofavonoid, a component of Cucuma longa L is attracting attention of researchers because of their effects and low toxicity. Objectives:To evaluate the hepatoprotective effect of curcuminoid on acute liver injury induced by carbon tetraclorid (CCl4 and paracetamol (PAR) in mice.) Subjects and method: Curcuminoid at doses of 60mg/kg and 120mg/kg were used in 8 consecutive days before hepatotoxins ( CCl4 0.5ml/kg in olive oil or PAR 400mg/kg) in mice.Results & Conclusion: Curcuminoid has hepatoprotective effect, expressed by reductions of serum levels of ALT, AST and liver histopathological injuries, in comparison with the control group ( which didn\u2019t use any drug). Curcuminoid at doses of 60mg/kg and 120mg/kg have hepatoprotective effect on acute liverinjury induced by carbon tetraclorid and paracetamol in mice. Curcuminoid at two different doses and silymarin at a dose 67mg/kg. The result showed that just low dose of curcuminoid (60mg/kg in mice) was enough to protect liver. It was just cheaper and safer than using high dose when using high dose the effect was not increase much.\r\n', u'\r\n', u'
Curcuma/ chemistry ; drug effects ; Drug-Induced Liver Injury

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