Objective: To study Blood Stasis Syndrome by molecular-biology in kidney-deficiency of diabetes pedigree.Methods: 18 members in diabetes pedigree were closed to make routine physical & chemical test and the macroscopic diagnosis of kidney-deficiency and blood stasis,3 diabetics with blood stasis syndrome and 2 healthy people in the same family,were selected to make 14000 genes chips hybrid test.Results: The pedigree maps and the comparative syndrome score tables of kidney-deficiency and blood stasis syndrome were obtained,and the 446 genes of different expressions,in particular,5 genes such as the TBXAS1,which was used to illustrate the possibility of effects on the blood stasis were also selected Conclusion: There was an exceeding preponderance of pedigree research method,which was used to search the macroscopic syndrome and the microscopic expressions of different genes.And it would help us to understand the relationship between the syndrome of kidney-deficiency & blood stasis diabetes and the genes of different expressions.

This article explored the pathology characteristic of the liver failing to maintain the normal flow of qi.It was considered that syndrome of depression of hepatic qi and reversed syndrome of hepatic qi were the main pathology characteristics of the liver failing to maintain the normal flow of qi,and its origin,development and present situation,as well as its diagnosis evidences and treatment methods and medicine were discussed.It also identified the significance of further standardizing the two syndromes of depression of hepatic qi and reversed of hepatic qi.

The characteristics of the pathogenic summer-heat and the primary important element of the season time dimension present parallelism principle on the forming mechanisms of five supremacies principal syndromes of initial summer febrile disease and four clinical characteristics of pathogenic factor summer heat. To explore the characteristics and the five successive evolutive phases corresponding to five elements phase theory of season and seasonal periods is provided with decisive guiding effect of passing through overall situation in the course of treating heat diseases caused by exogenous pathogenic factor based on syndrome differentiation in terms of the syndrome recognizing,establishing therapy principle and selecting Chinese materia medica to from a formula.It also presents effective resources and thoughts used for reference on the "bird flu" of nowadays,influenza of the human being(epidemic) that is likely to break out and how to treat these super-variations of virus(pestilential qi) based on syndrome differentiation with traditional Chinese medicine.

To discuss the essence of six meridians,the key point is the comprehension of three yin and three yang.Three yin and three yang describes the six natural states of re-division and reunion of yin and yang.The opening,closing and pivot of three yin and three yang determine the property and characteristic of each Meridian.It is necessary to understand three yin and three yang by the theory of five movements and six qi as the comprehension of different states in space-time,azimuth and yin-yang qi.If we discuss six meridians from the view of the theory of five movements and six qi,most of the previous puzzles could be solved reasonably.The dynamic space-time variations among three yin and three yang is well-ordered.Syndrome-differentiation according to the theory of three yin and three yang could well reflex the dynamic space-time characteristics of the whole changes of internal and external environments when disease happens.The theory of six meridians must be mentioned as lecturing Treatise on Cold Pathogenic Diseases(Shanhan Lun),and the syndrome-differentiation of the six meridians can not be abolished.

According to the historical records such as The Rules and Regulations in Force of the Ministry of Internal Affairs and raw files of the Ministry of Internal Affairs of the Qing Dynasty(1644-1911) kept in the First Historical Archives of China,a systematic study was made on the establishment,cancel and restoration of the Imperial Drug Institution,the medical organization of the Qing Dynasty after Beijing was established as its capital.A textual research was made into the scale of all the personnel such as officials and bailiffs in the Imperial Drug Institution throughout the Qing Dynasty.All the researches reflect the course of change and development of the imperial medical organizations in the Qing Dynasty.

Though the clinical observation of 413 cases of epidemic hemorrhagic fever(EHF) by clinical epidemiological method,we have concluded that the main TCM etiological factors of EHF are damp,toxic heat,blood stasis and deficiency, and the determinant pathogenesis of EHF is the integration of interior and exterior pathogenic factors;the syndrome characteristic of EHF is that the cold,heat,deficiency and excess were intermingled,and the moist heat blood stasis syndrome should be given priority to;its major pathological location is initial YANG and triple warmer;so the therapeutic principle should be the integration of cold-warm syndrome and exterior and interior and paying attention to smoothing the triple warmer all the time.

Sub-health is a state between healthiness and disease.It communicates with the theory of the constitution factor of traditional Chinese medicine(TCM) and the thought of preventive treatment of disease;Sub-health involves psychosomatic.It is related with TCM emotional stress,emphasizes differential diagnosis according to state of viscera as well;Complicated variety in sub-health symptom is dealt with synthetically regulation of TCM and characteristic therapy.This article discussed and analyzed the prevention and cure strategy of traditional Chinese medicine according to the characteristic of sub-health condition.

Due to the history reasons,it was believed that Zhang Zhongjing wrote Treatise on Cold Pathogenic Diseases(Shanghan Lun) according to Inner Canon of Huangdi(Huangdi Nei Jing),thus Treatise on Cold Pathogenic Diseases(Shanghan Lun) was explained by means of six channels,zang-fu viscera and meridian from Inner Canon of Huangdi(Huangdi Nei Jing),so that we can not comprehend medical science of Zhang Zhongjing correctly.By textual research data confirmed,Treatise on Cold Pathogenic Diseases(Shanghan Lun) written by Zhang Zhongjing was not according to Inner Canon of Huangdi(Huangdi Nei Jing),its main content formulae-syndromes was coming from Tangye Jing Fa etc classical formulae medicine.Treatise on Cold Pathogenic Diseases mainly inherited differentiation of syndromes by eight principles and added half exterior and half interior concept to form differentiation of syndromes by six channels theory,in this way,it made six channels as key line,formulae-syndromes as item,coming into being the unique system of treatment based on syndrome differentiation."Six channels" in Treatise on Cold Pathogenic Diseases and Inner Canon of Huangdi has different theory concepts,so when readouting Treatise on Cold Pathogenic Diseases,we should not confuse the two concepts.

The origin of the word "male external genitals(Zongjin)" is coming from Inner Canon of Huangdi(Huangdi Nei Jing).This article synthesized the theories of past dynasties' doctors.It made a systemic statement on "male external genitals" in terms of the concept,physiological functions and the contacting effect with correlated meridian and vessels for the first time,so as to enrich the theory of visceral manifestations in TCM.Meanwhile,it also pointed out the significance and specific application of the theory that treating impotence based on "male external genitals",thereby provided a new view of treating "male external genitals" in TCM clinic.

Objective: To discuss the research evolution of blackish facial patch. Methods: According the literatures of past dynasties,the research connotations of blackish facial patch in each dynasty were inspected.Results: During the Warring States era,the name,etiology,pathogenesis,diagnosis and treatment of blackish facial patch had preliminary study,only formulae and drugs absence.In Han and Tang Dynasties,it had proposed the alias of "dustycomplexion" and "blackish and withered face" etc,the etiology of phlegm and drink soiled inside of the body,striae and interstitial space suffering wind,the pathogenesis of hepatic and renal yin deficiency,weakness of the spleen and stomach,moist heat,obstruction of collaterals by blood stasis and discordance of blood-qi,the syndrome description of face like suffering dust,or black as lacquer wood or like tree sparrow egg on the color,and the treatments of formulae and drugs,acupuncture and massage etc;all of the contents were superficial.After the Song Dynasty, the study of etiology,pathogenesis and syndrome were deepen and expanded,and it had increased the pathology concepts of blood weak and kidney deficiency,domination of dryness of Yangming,dry and gloomyof the lung and hepatic and cholic fire prosperous,and the therapeutic tools and drugs were more abundant and concrete than ever,but that literatures were still fragmented and not being a system,without monographs.Entering the modern era,just as the Qing Dynasty,had not any breakthrough.Until the liberation,especially since the 80s of the last century,with the rise of cosmetology in traditional Chinese medicine,the research on blackish facial patch both in form and content dark blotches has achieved unprecedented progress.Conclusion: Understanding the origin and development of blackish facial patch,it will play a fundamental role in the future in-depth study.