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Efficacy of ambroxol combined with budesonide inhalation in the treatment and intervention of neonatal pneumonia

Chinese Journal of Biochemical Pharmaceutics.2017;37(8):122-123,126. doi:10.3969/j.issn.1005-1678.2017.08.049

Objective To explore and analyze the effect of ambroxol hydrochloride combined with budesonide inhalation in the treatment of neonatal pneumonia and intervention treatment. Methods May 2014 to March 2017, Taizhou Hospital for treatment of pneumonia in infants, a total of 100 cases of the research object, according to the different treatment methods of the infant patients into the control group and the study group, 50 cases in each group. The study group were treated with ambroxol combined with budesonide inhalation treatment methods, patients in control group were treated with budesonide inhalation treatment methods, two patients were given nursing intervention on in the process of treatment, observation and comparison of two groups of children were observed two different quality methods the therapeutic effect. Results The children of patients with treatment effect was stronger than the control group, the difference is statistically significant(P<0.05). The study of the recovery time and hospitalization time were significantly less than the control group, with statistically significant difference (P<0.05). The degree of satisfaction with nursing is significantly better than the control group(P<0.05). Conclusion The treatment method of neonatal pneumonia ambroxol combined with budesonide inhalation, and implement the corresponding nursing intervention, can effectively improve the clinical symptoms of patients, improve lung function in patients, improve the therapeutic effect, shorten the patient's symptoms disappeared time and hospitalization time, children can not only improve the standard of living of the patients, but also enhance the degree of recognition of the hospital and nursing care of patients thus, play a role in the promotion.

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Treatment and intervention effect of Atrovent aerosol inhalation analysis in patients with chronic obstructive pulmonary disease respiratory failure

Xiaoping ZHU ; Jiayou LUO

Chinese Journal of Biochemical Pharmaceutics.2017;37(8):119-121. doi:10.3969/j.issn.1005-1678.2017.08.048

Objective To investigate the effects of Atrovent aerosol inhalation in the treatment of respiratory failure and nursing intervention of chronic obstructive pulmonary disease effect. Methods January 2016 to December 2016 in Huzhou Central Hospital for diagnosis and treatment of chronic obstructive pulmonary disease patients with respiratory failure in 50 cases dewided into control group and observationgroup: the control group treated with conventional methods, the observation group treated with Atrovent aerosol inhalation therapy and conventional methods; the patients in the two groups of experimental data were recorded in detail, and the obtained data were analyzed. Results The observation group was better than that of treatment and intervention control group, clinical symptoms improved better than the control group, the adverse reaction rate were lower than the control group, there is significant statistical difference (P<0.05). Conclusion The patients with chronic obstructive pulmonary disease with respiratory failure choose conventional and Atrovent aerosol inhalation treatment effect significantly, can effectively improve the patient clinical symptoms and adverse reactions are few and deserve to be widely used in the treatment of chronic obstructive pulmonary diseaseand respiratory failure patients.

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Efficacy of somatostatin combined with omeprazole in the treatment and intervention of liver cirrhosis with upper gastrointestinal bleeding

Juanjuan HONG ; Xiuxiu JIN

Chinese Journal of Biochemical Pharmaceutics.2017;37(8):117-118,121. doi:10.3969/j.issn.1005-1678.2017.08.047

Objective To investigate the effects of somatostatin combined with omeprazole in treatment of digestive tract hemorrhage and the intervention effect in cirrhosis. Methods According to the different treatment methods will be January 2015 to January 2017 in Taizhou Hospital treatment of gastrointestinal bleeding in patients with cirrhosis 80 cases groups: control group was treated with omeprazole and omeprazole and somatostatin in the treatment of observation group; two groups were recorded in the experimental data, and the data were analyzed, the effect of somatostatin combined with omeprazole in treatment of digestive tract hemorrhage and the intervention effect in patients with liver cirrhosis. Results The observation group clinical treatment effect is better than that of control group clinical treatment groups was statistically significant the difference between (P< 0.05). Conclusion The bleeding patients choose somatostatin omeprazole treatment effect on liver cirrhosis digestive adverse little response.

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Effect of aminophylline on the related indexes in perioperative period in thoracic surgery

Zhenzhen WU ; Junrong DING

Chinese Journal of Biochemical Pharmaceutics.2017;37(8):113-116. doi:10.3969/j.issn.1005-1678.2017.08.046

Objective To investigate the therapeutic effect of aminophylline on the treatment of patients with thoracic surgery perioperative. Methods 230 cases with thoracic surgery were selected as the research objects and divided into the research group and the control group randomly, and there was 15 cases in each group. the control group were ginven closed drainage of thoracic cavity during the surgery, continued to 3 days after surgery. The control group were given intravenous drip of ciprofloxacin lactate injection at 12 h after operation, and the treatment lasted for 7 days. At this basis, the research group were given aminophylline 0.5 mg/d by intravenous injection at the beginning of anesthesia induction and continued for 3 days. The levels of lung and respiratory inflammation related factor (White blood cells, PCT, hs-CRP, TNF-α, IL-6, IL-8 and IL-10), blood gas index in the two groups pre- and post–surgery were detected, and the complications and adverse drug reactions were observed. Results 24h after surgery, TNF alpha, IL-6, IL-8 were significantly lower than those in the control group (P<0.05), and IL-10 level was significantly higher than that in the control group (P<0.05). And PaO2 in the research groupwas significantly higher than that in the control group patients (P<0.05). After treatment, arterial carbon dioxide partial pressure (PaCO2) in the two groups were significantly lower than preoperative (P<0.05). The complication rate in the research group was significantly lower than that in the control group within ten days(P<0.05). There were no adverse reactions in both groups. Conclusion During the perioperative period in thoracic surgery, aminophylline intervention can effectively improve the prognosis. .

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Clinical study of solanine combined with tamsulosin in the treatment of typeⅢprostatitis

Xiao XU ; Libo MAN ; Guizhong LI ; Ning ZHOU

Chinese Journal of Biochemical Pharmaceutics.2017;37(8):111-112,116. doi:10.3969/j.issn.1005-1678.2017.08.045

Objective To investigate the clinical study of sarcoside combined with tamsulosin in the treatment of type Ⅲ prostatitis. Methods 84 patients with type Ⅲ prostatitis who were treated and diagnosed in Jishuitan Hospital from November 2015 to December 2016 were randomly divided into experimental group and control group according to the time of hospitalization, 42 cases in each group. The control group was treated with tamsulosin hydrochloride sustained-release capsules, and the experimental group was treated with the addition of the new drug. The maximum urinary flow rate and mean urinary flow before and after treatment were recorded, compared and analyzed before and after treatment. Results The maximum urinary flow rate and mean urinary flow rate were increased in both groups after treatment, and there was significant difference between the two groups (P<0.05). The data of the maximum urinary flow rate and the mean urinary flow rate in the experimental group were significantly better than those in the control group. The data of the two groups were statistically significant (P<0.05). In addition, the experimental group after treatment of prostate symptom score was significantly better than the control group score, the two groups of data were significantly different, the data were statistically significant (P<0.05). In addition, the total effective rate of the experimental group was significantly higher than the control group(80.95%vs. 73.81%). The data were statistically significant (P<0.05). Conclusion The clinical efficacy of sorbenaside combined with tamsulosin in the treatment of type Ⅲ prostatitis is better than that of the original treatment. The treatment can improve the patient's urination and prostate symptoms and improve the patient's comfort.

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Comparison on the effect of sufentanil and remifentanil combined with propofol anesthesia in hysteroscopic surgery

Qiaoling LU ; Jie ZHOU ; Huamin YE ; Lipei LEI

Chinese Journal of Biochemical Pharmaceutics.2017;37(8):106-107,110. doi:10.3969/j.issn.1005-1678.2017.08.043

Objective To compare the anesthetic effect of sufentanil combined with propofol and remifentanil combined with propofol in hysteroscopic surgery, and to provide a scientific basis for the selection of clinical anesthesia methods. Methods From November 2016 to March 2017, 94 patients in Lishui central hospital underwent hysteroscopic surgery were divided into the observation group and the control group according the anesthesia way, 47 cases in each group. The control group were given remifentanil(1 μg/kg) combined with propofol(2 mg/kg) by intravenous injection, the observation group were given sufentanil(0.2 μg/kg) combined with propofol(2 mg/kg). The mean arterial pressure(MAP), respiration (RR), pulse oxygen saturation (SpO2), heart rate (HR), the onset time of anesthesia, the postoperative recovery time, the recovery time of orientation and Ramsay sedation score in the two groups were recorded and compared before anesthesia, 2 min after anesthesia, 10 min after operation, 10min after operation finished. Results Compared with before anesthesia, MAP, RR, SpO2, HR index decreased significantly after anesthesia, the differences have statistical significance (P<0.05), the control group compared to the index value, the observation group and the control group of convergence and the decline of difference, group showed no statistically significant difference the observation group was more stable; comparison between the 10min group and MAP HR index after surgery, there was significant difference between two groups (P<0.05). The onset time of anesthesia, postoperative recovery time, orientation recovery time, Ramsay score difference between the groups was not statistically significant sedation score difference was statistically significant between group VAS, observation group than in the control group (P<0.05). Conclusion Sufentanil combined with propofol anesthesia were used in hysteroscopic surgery, which can better maintain the vital signs of patients, effectively reduce postoperative pain.

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Analyze on the influence of minocycline combined with azithromycin on serum CRP, D-Dimer and lung function in the children with refractory mycoplasma pneumonia

Jing LI ; Xueyan WANG ; Mengjuan WANG ; Cui WANG ; Guochao SONG

Chinese Journal of Biochemical Pharmaceutics.2017;37(8):102-105. doi:10.3969/j.issn.1005-1678.2017.08.042

Objective To study the influence of minocycline combined with azithromycin on serum CRP, D-Dimer and lung function in the children with refractory mycoplasma. Methods From April 2015 to August 2016, 42 children with refractory mycoplasma pneumonia were enrolled in the second hospital in Tianjing. The patients were divided into the observation group and the control group according to the order of admission. The control group was treated with azithromycin sequential therapy, the observation group were given minocycline combined with azithromycin to complete the treatment. The levels of serum CRP, D-D, lung function, clinical symptoms and signs, and the adverse effects were observed. Results After treatment, the total effective rate of the observation group was significantly higher than that in the control group (P<0.05). The levels of CRP and D-D in the observation group were significantly lower than those in the control group (P<0.05). The highest expiratory flow velocity (PEE), first-second forced expiratory volume (FEV1), forced vital capacity (FVC) and forced expiratory 25% flow rate (MEF25) in the observation group were significantly higher than those in the control group (P<0.05). The time of X-ray recovery time, the time of fever, the time of cough and the disappearance of lung rales were significantly shorter than those in the control group (P<0.05). Compared with the control group, there were no significant differences in diarrhea, abdominal pain, nausea, vomiting, pleural effusion, otitis media, mild anemia and rash adverse reaction rate in the observation group. Conclusion Minocycline combined with azithromycin in the treatment of severe Mycoplasma pneumoniae pneumonia can effectively reduce serum levels of CRP and D-D, improve pulmonary function and clinical symptoms, and have good clinical efficacy.

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Study on the effects of L-carnitine combined with hemodialysis on nerve conduction velocity and quality of life in patients with uremic peripheral neuropathy

Aijie HUAGN

Chinese Journal of Biochemical Pharmaceutics.2017;37(8):100-101,105. doi:10.3969/j.issn.1005-1678.2017.08.041

Objective To investigate the effect of levocarnitine combined with hemodialysis on nerve conduction velocity and quality of life in patients with uremic peripheral neuropathy. Methods A total of 71 patients with uremic peripheral neuropathy were randomly divided into two groups according to the random number table. 35 patients in the control group were treated with hemodialysis. The observation group (36 cases) was treated with hemodialysis and levocarnitine. The sensory nerve conduction velocity in the median nerve, the tibial nerve and peroneal nerve, and clinical efficacy and quality of life (QOL) score in the two groups were compared. Results The rate of nerve conduction in the observation group was significantly higher than those in the control group (P<0.05). The total effective rate was 88.89% (32/36) in the observation group, which was higher than 68.57% (24/35) in the control group (P<0.05). The scores of QOL in the observation groups was higher than that in the control group (P<0.05). Conclusion The combination of levocarnitine and hemodialysis can improve the nerve conduction velocity and quality of life in patients with uremic peripheral neuropathy.

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Observation on curative effect of ozone combined with nifuratel nystatin vaginal soft capsules on the treatment of vaginitis

Caihua YANG ; Shanghua LIU ; Wenli ZHANG

Chinese Journal of Biochemical Pharmaceutics.2017;37(8):97-99. doi:10.3969/j.issn.1005-1678.2017.08.040

Objective To explore the clinical effect of ozone combined with nifuratel nystatin vaginal soft capsules on the treatment of vaginitis, and to provide the basis for clinical application. Methods 204 patients with vaginitis in our hospital from January 2013 to December 2016 were divided into the observation group (114 cases) and the control group (90 cases) according to the different treatment methods. The control group was treated with nifuratel nystatin vaginal soft capsules, and the observation group was treated with ozone combined with nifuratel nystatin vaginal soft capsules. The clinical efficacy, symptom relief time and adverse reaction were compared between the two groups. Results After treatment, the total effective rate in the observation was 97.37%, which was significantly higher than 85.56% in the control group(P<0.05). The rapid remission rate of the clinical symptoms in the observation group was significantly higher than that in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion The effect is significant that ozone combined with nifuratel nystatin vaginal soft capsules is used on the treatment of vaginitis, which can quickly relieve symptoms, and will not significantly increase the adverse reactions, is worthy of application.

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Efficacy of docetaxel combined with pirarubicin in the treatment of advanced breast cancer

Daoxia PAN ; Huiwen YANG

Chinese Journal of Biochemical Pharmaceutics.2017;37(8):95-96,99. doi:10.3969/j.issn.1005-1678.2017.08.039

Objective To investigate the nursing intervention and efficacy of docetaxel combined with pirarubicin in the treatment of advanced breast cancer. Methods In our hospital from January 2014 to February 2015 were selected from the patients with advanced breast cancer in 94 cases as the research object, the single and double number (hospital admission order) of the selected patients with advanced breast cancer were randomly divided into study group and control group, 41 cases in each group. 2 groups of patients with advanced breast cancer were treated with docetaxel combined with pirarubicin, the control group was given routine nursing services, and the study group was given comprehensive nursing intervention measures on the basis of routine care. Results Of the 2 groups of patients with advanced breast cancer nursing after different nursing measures the same drug plan, after the study group, the total efficiency of treatment in the method [please explain what is near total efficiency] (82.98%) was significantly better than the control group (61.70%), the difference was statistically significant (P<0.05); the study group the nursing service satisfaction was significantly better than the control group (P<0.05). Conclusion With the combination of docetaxel and pirarubicin in the treatment of advanced breast cancer patients, comprehensive nursing measures can achieve better clinical efficacy and benefit the maintenance of good relationship between nurses and patients.

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