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Development current situation of optical coherence tomography in percutaneous coronary intervention

Chinese Journal of cardiovascular Rehabilitation Medicine.2014;23(2):233-237. doi:10.3969/j.issn.1008-0074.2014.02.36

Optical coherence tomography (OCT)is thought to be the most effective tool for recognizing form of vul-nerable plaques and evaluating endothelium coverage after percutaneous coronary intervention (PCI)so far.OCT can be used to guide stent implantation,evaluate endothelium proliferation status in stent,explore causes for in-stent restenosis and detect stent late malapposition and in-stent thrombosis etc.

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Correlation between MicroRNAs and cardiovascular diseases

Chinese Journal of cardiovascular Rehabilitation Medicine.2014;23(2):230-233. doi:10.3969/j.issn.1008-0074.2014.02.35

MicroRNAs (miRNAs)is a kind of highly conserved endogenous un-encoded single chain micromolecule RNA, Which modulates gene expression via degrading mRNA or inhibiting protein translation. A lot of researches have proved that miRNA plays an important role in cause,development,diagnosis and treatment of cardiovascular diseases.This article made an overvieW on research progress for correlation betWeen miRNAs and cardiovascular diseases.

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Heart rate turbulence phenomenon and metoprolol intervention effect in patients with essential hyper-tension

Leiyi ZHANG ; Shenghang LIU ; Xiaofang SUI

Chinese Journal of cardiovascular Rehabilitation Medicine.2014;23(2):224-226. doi:10.3969/j.issn.1008-0074.2014.02.33

Heart rate turbulence (HRT)can Well reflect autonomic function.There usually exist different degrees of autonomic impairment in patients With hypertension.As a selectiveβ1 receptor blocker,metoprolol can not only de-crease patients' blood pressure,but also inhibit sympathetic activity,improve vagal activity and HRT in these pa-tients.This article made folloWing overvieW on HRT phenomenon and metoprolol intervention effect in patients With hypertension.

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Research progress of percutaneous renal sympathetic radiofrequency ablation treating hypertension

Xiaodan XU

Chinese Journal of cardiovascular Rehabilitation Medicine.2014;23(2):227-230. doi:10.3969/j.issn.1008-0074.2014.02.34

Hypertension is a main risk factor for cardio-,cerebrovascular and renal diseases.Catheter-based renal sympathetic ablation provides a neW therapeutic method for hypertension, it shoWs effective antihypertensive and sympathetic denervation effects,and obtains additional benefits While treating hypertension.

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Causes and progress of prevention and treatment for very late stent thrombosis after drug-eluting stent ;implantation

Chunling WANG

Chinese Journal of cardiovascular Rehabilitation Medicine.2014;23(2):221-224. doi:10.3969/j.issn.1008-0074.2014.02.32

Drug-eluting stent can effectively decrease stent restenosis rate and revascularization of target vessels,but compared With bare-metal stent, there Was an increasing trend in incidence rate of very late stent thrombosis (VLST).Some study indicated that delayed re-endothelialization,anti-platelet drug resistance after drug-eluting stent thrombosis after drug-eluting stent implantation and operation technique of percutaneous coronary intervention (PCI)Were closely related to late thrombosis.This article made folloWing overvieW on cause,risk factors and pre-ventive and therapeutic strategy of VLST.

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Renal sympathetic nerve ablation treatment for hypertension and its research progress

Sha WANG ; Shufeng LI

Chinese Journal of cardiovascular Rehabilitation Medicine.2014;23(2):218-220. doi:10.3969/j.issn.1008-0074.2014.02.31

Excessive activation of renal sympathetic nerves may be a key factor for occurrence and maintenance of hypertension.Renal sympathetic nerve ablation is a selective sympathetic denervation therapy,Which provides neW route for antihypertensive treatment.This article made an overvieW on further expansion of safety,effectiveness and indications of renal sympathetic nerve ablation treatment for hypertension.

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Nursing of postoperative complications of percutaneous coronary intervention in patients with coronary heart ;disease

Li RAN

Chinese Journal of cardiovascular Rehabilitation Medicine.2014;23(2):213-214. doi:10.3969/j.issn.1008-0074.2014.02.29

Objective:To observe the postoperative complications of percutaneous coronary intervention (PCI)in pa-tients With coronary heart disease (CHD)and analyze its nursing methed.Methods:A total of 200 CHD patients un-dergoing PCI in our hospital from Sep 2011 to Aug 2012 Were enrolled.The postoperative complications and thera-peutic effect Were observed and analyzeits nursing methods.Results:There Were 42 cases of PCI postoperative com-plications,included 26 cases (13%)of forearm hematoma,five cases (2.5%)of errhysis and edema at puncture site,four cases (2%)of extubation syndrome,tWo cases (1%)of arrhythmia and tWo cases (1%)of pseudoaneu-rysm etc.,in Which the incidence of forearm hematoma Was the highest,compared With any other complication (P<0.05 );after direction nursing,all complications significantly improved and recovered to normal.Conclusion:Comprehensive and directive nursing can effectively prevent postoperative complications and promote rehabilitation as soon as possible in patients With coronary heart disease after percutaneous coronary intervention.

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Coronary angiographic data analysis in young male patients with type 2 diabetes mellitus complicated ;coronary heart disease

Aihua ZHANG ; Zhengyan ZHU ; Hongwei ZHANG ; Xiaojuan LIU

Chinese Journal of cardiovascular Rehabilitation Medicine.2014;23(2):194-196. doi:10.3969/j.issn.1008-0074.2014.02.23

Objective:To explore the coronary angiographic (CAG)characteristics of young male patients With type 2 diabetes mellitus (T2DM)and coronary heart disease (CHD).Methods:Clinical data of 233 young male CHD inpa-tients,Who Were confirmed by CAG and admitted in Beijing Shunyi Hospital from Jan 2011 to Jan 2013,Were retro-spectively analyzed.According to suffering from T2DM or not,they Were divided into T2DM + CHD group (n=71)and pure CHD group (n=162),baseline data and CAG results Were compared betWeen tWo groups.Results:Compared With pure CHD patients,there Were significant rise in levels of total cholesterol [TC,(4.11 ± 0.26) mmol/L vs.(5.79±0.37)mmol/L],loW density lipoprotein cholesterol [LDL-C,(2.31±0.32)mmol/L vs.(3.91 ±0.45)mmol/L],triglyceride [TG,(1.60±0.25)mmol/L vs.(3.28±0.56)mmol/L],P<0.01 all;CAG indi-cated that there Were significant increase in percentages of multi-vessel coronary disease (15.4% vs.35.2%),seg-mental lesion (13.6% vs.35.2%)and diffused lesion (31.5% vs.57.7%),and significant reduction in percentage of collateral circulation (50.6% vs.29.6%)in T2DM + CHD patients,P<0.01 all.Conclusion:There are more multi-vessel lesions,diffused lesion and less coronary collateral circulation in young male patients With type 2 diabe-tes mellitus complicated coronary heart disease.

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Clinical significance of combined detecting multiple indexes for early renal damage in patients with hy-pertension

Fangmei WEN ; Qing TANG ; Jianyu YAN

Chinese Journal of cardiovascular Rehabilitation Medicine.2014;23(2):191-193. doi:10.3969/j.issn.1008-0074.2014.02.22

Objective:To explore the clinical significance of combined detecting serum cystatin C (Cys-C),retinol binding protein (RBP),high sensitive C reactive protein (hsCRP)and urine microalbuminuria (UMA)for early re-nal damage detection in patients With essential hypertension (EH).Methods:Levels of Cys-C,RBP and UMA Were measured in 83 EH patients (EH group)and 80 healthy objects With similar age (healthy control group)respective-ly.Positive rates (exceeding upper limit of normal value for above index Was regarded as positive) of single and combined use of above indexes Were calculated.Results:Compared With healthy control group,there Were signifi-cant increase in levels of Cys-C [(0.98±0.30)μg/ml vs.(1.23±1.38)μg/ml],RBP [(38.32±10.10)mg/L vs. (41.67±11.68)mg/L],and UMA [(1.17±0.46)mg/L vs.(3.01±3.31)mg/L]in EH group (P<0.05 or <0.01),and their detection rates for early renal damage Were 21.69%,19.28%,14.46% and 19.28% respectively. Combined detecting rates of Cys-C + UMA and UMA+ RBP Were 36.14% and 34.94% respectively,Which Were significantly higher than those of single index (P<0.05 all).Conclusion:Proper multi-index combined detecting can effectively raise the detection rate of early renal damage in patients With hypertension.

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Value of plasma NT-proBNP assessing prognosis of patients with diastolic heart failure complicated dia-betes mellitus

Jiang LI ; Huawen LIANG ; Haiyan YANG ; Shenglian LIU

Chinese Journal of cardiovascular Rehabilitation Medicine.2014;23(2):137-140. doi:10.3969/j.issn.1008-0074.2014.02.07

Objective:To explore value of plasma N terminal pro B type natriuretic peptide (NT-proBNP)assessing prognosis of patients With diastolic heart failure (DHF)complicated type 2 diabetes mellitus (T2DM).Methods:The folloW-up data of 206 inpatients With DHF and T2DM from our hospital Were retrospectively analyzed.Ac-cording outcome,they Were divided into no event group (n=108)and event group [n=98,With major adverse car-diovascular events (MACE)occurred].Levels of NT-proBNP,glycosylated hemoglobin (HbA1c),total cholesterol (TC)and loW density lipoprotein cholesterol (LDL-C),left ventricular end-diastolic dimension (LVEDd),left ventricular peak early diastolic velocity/peak late diastolic velocity (E/A)and left ventricular ejection fraction (LVEF)during admission Were measured and compared betWeen tWo groups. Results:Compared With no event group,there Were significant increase in NT-proBNP level and LVEDd,and significant decrease in LVEF and E/A in event group (P<0.05 all).Single factor linear analysis indicated that NT-proBNP,HbA1c,LVEDd and E/A Were positively correlated With MACE incidence rate (r=0.075~0.091,P<0.05 all).Mutivariate Logistic regres-sion analysis indicated that NT-proBNP Was an independent predictor for MACE (OR=1.003,P=0.009).Areaunder recieve operating characteristic curve (ROC)Was 0.803 for NT-proBNP predicting mortality of patients during admission (P <0.05),and survival rate of patientsWith plasma NT-proBNP≤4010pg/mlWas significantly higher than that of patients With NT-proBNP>4010 pg/ml (OR=5.028,P <0.05).Conclusion:Plasma NT-proBNP can independently predict prognosis of patients With diastolic heart failure complicated type 2 diabetes mellitus.

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