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A study on evaluation of heart function after percutaneous coronary intervention by real-time three-di-mensional echocardiography

Guo TAO

Chinese Journal of cardiovascular Rehabilitation Medicine.2015;24(3):329-332. doi:10.3969/j.issn.1008-0074.2015.03.30

Objective:To explore application value of real-time three-dimensional echocardiography (RT-3DE ) for heart function evaluation after percutaneous coronary intervention (PCI) .Methods:Clinical data of 45 patients with coronary heart disease (CHD) collected from Jan 2013 to Jan 2014 in our hospital were enrolled .All patients received selective coro-nary angiography (CAG) and PCI .Another 45 healthy cases undergoing physical examination during the same period were selected as normal control group .End-diastolic volume (EDV) ,end-systolic volume (ESV) ,left ventricular ejection frac-tion (LVEF) ,peak ejection rate (PER) and peak filling rate (PFR) were measured by RT-3DE and two-dimensional echo-cardiography (2DE) respectively and compared between two groups .Results:In normal control group ,there were no sig-nificant differences in all indexes between two measuring methods ,P>0.05 all;in CHD group ,compared with 2DE meas-ured value ,there were significant rise in EDV [ (130.6 ± 30.3) ml vs .(152.5 ± 35.2) ml] ,ESV [ (75.2 ± 21.8) ml vs . (94.1 ± 22.5) ml] ,PER [(2.41 ± 0.47) vs .(2.81 ± 0.39)] and PFR [(1.85 ± 0.25) vs .(2.13 ± 0.31)] ,and significant reduction in LVEF [ (45.8 ± 5.2)% vs .(41.6 ± 4.9)% ] in RT-3DE ,P<0.01 all;on one week ,one month and three months after PCI ,EDV and ESV gradually reduced ,LVEF ,PER and PFR gradually rose in CHD group with significant difference ,P<0.05 or <0.01 .Conclusion:RT-3DE can perform direct ,accurate and quantitative evaluation on heart form and function before and after PCI ,which is a reliable ,fast ,simple and new method evaluating PCI therapeutic effect in CHD patients .

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Study for cardiac systolic synchronization in patients with ischemic cardiomyopathy

Chao WAN ; Pin SUN ; Yang JI ; Shanglang CAI

Chinese Journal of cardiovascular Rehabilitation Medicine.2015;24(3):326-329. doi:10.3969/j.issn.1008-0074.2015.03.29

Objective:To explore value of pulsed wave (PW) and tissue synchronization imaging (TSI) evaluate cardi-ac systolic synchronization in patients with ischemic cardiomyopathy (ICM) .Methods:A total of 50 ICM patients were enrolled as ICM group and 35 healthy volunteers without organic heart disease were regarded as healthy control group ,PW was used to measure mitral diastolic blood flow duration/RR interval (LVFT/RR) to evaluate synchroni-zation of left atrial and left ventricular synchronization ;interventricular mechanical delay (IVMD) was measured to evaluate left and right ventricular synchronization ;TSI software was used to measure mitral annular mean systolic peak velocity (LV-Sm) ,systolic time to peak (Ts) and Ts standard deviation (Ts-SD) of all segments in order to e-valuate left ventricular systolic synchronization .Results:Compared with healthy control group ,there were signifi-cant reductions in LVFT/RR [ (44.74 ± 1.58)% vs .(41.08 ± 4.65)% ] and LV-Sm [ (9.72 ± 0.53) ms vs .(4.09 ± 1.06) ms] ,and significant rise in IVMD [ (15.51 ± 5.52) ms vs .(41.96 ± 4.20) ms] and Ts-SD [ (16.47 ± 4.16) ms vs .(34.13 ± 11.68) ms] in ICM group , P<0.01 all;Ts of anterior wall ,inferior wall et .6 positions were significantly longer ,and its synchronization significantly reduced , P<0. 05 all ,percentages of the most de-layed systolic part of left ventricle were no significant differences between two groups (P> 0.05) .Conclusion:Compared with healthy control group ,left ventricular total systolic function ,left atrial&ventricular ,left&right ventricular synchronization and systolic synchronization within left ventricular significantly reduce in ICM patients .

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Therapeutic effect of atorvastatin therapy of different doses on acute coronary syndrome

Zhengyuan YUAN ; Zijie XIAO

Chinese Journal of cardiovascular Rehabilitation Medicine.2015;24(3):322-325. doi:10.3969/j.issn.1008-0074.2015.03.28

Objective:To explore the optimal dose of atrovastatin treating acute coronary syndrome (ACS) .Methods:A total of 86 ACS patients were randomly and equally divided into atorvastatin large dose group (40 mg/d) and rou-tine dose group (20 mg/d ) . Blood lipid levels , blood lipid standard-reaching rate , serum levels of adiponectin (APN) and high sensitive C reactive protein (hsCRP) were compared between two groups before and after treat-ment .All patients were followed up for six months after discharge ,and incidence rates of cardiovascular events and adverse reactions were compared between two groups .Results:Compared with routine dose group ,the levels of TC and LDL-C significantly reduced on 3 months after treatment ,in large dose group (P<0.01 ,<0.05 respectively);the standard-reaching rates of TC and LDL-C [TC:(23.3% vs .44.2% ) ,LDL-C:(37.2% vs .60.5% ) ,P<0.05 all];level of APN [ (8.47 ± 1.73) mg/L vs .(12.96 ± 2.15) mg/L] significantly rose ,level of CRP [ (6.23 ± 1.26) mg/L vs .(4.07 ± 1.54) mg/L] significantly reduced ,P<0.01all;incidence rate of adverse cardiovascular e-vents (23.3% vs .7.0% , P= 0.035) significantly reduced ,but there was no significant difference in incidence rate of adverse reactions between two groups ,P=0.213.Conclusion:Atorvastatin therapy can effectively reduce in-cidence rate of cardiovascular events in ACS patients ,and the dose 40mg/d is optimal dose .

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Therapeutic effect of cilazapril and amlodipine on QT interval dispersion and arrhythmia in patients with essential hypertension

Jianhua ZHOU ; Huihui WU

Chinese Journal of cardiovascular Rehabilitation Medicine.2015;24(3):319-322. doi:10.3969/j.issn.1008-0074.2015.03.27

Objective:To study therapeutic effect of cilazapril and amlodipine on QT interval dispersion and arrhyth-mia in patients with essential hypertension (EH) .Methods:A total of 120 EH patients complicated with ventricular arrhythmia in our hospital from Mar 2011 to Mar 2014 were enrolled ,randomly and equally divided into cilazapril group and amlodipine group ,the two groups all received routine antihypertensive therapy .Blood pressure ,QT in-terval and arrhythmias were compared between two groups .Results:Compared with amlodipine group ,there were significant reductions in 24h mean systolic blood pressure [24hSBP ,(123.81 ± 17.95) mmHg vs .(104.92 ± 14.25) mmHg] ,24h mean diastolic blood pressure [24hDBP ,(88.31 ± 10.28) mmHg vs .(72.24 ± 8.45) mmHg] ,24hSBP variability [ (11.62 ± 1.34) mmHg vs .(7.34 ± 0.97) mmHg] ,24hDBP variability [ (9.47 ± 1.18) mmHg vs .(5.13 ± 0.72) mmHg] ,QT interval [ (385.1 ± 50.4) ms vs .(342.7 ± 48.5) ms] ,corrected QT interval [ (362.7 ± 50.2) ms vs .(321.8 ± 45.1) ms] and QT interval dispersion [ (34.1 ± 5.1) ms vs .(22.5 ± 3.7) ms] in cilazapril group , P<0.05 or <0.01;ventricular arrhythmia class in cilazapril group was significantly better than that of amlodipine group , P<0. 05. Conclusion:Therapeutic effect of cilazapril is more helpful to reduce blood pressure ,QT interval dispersion and improve ventricular arrhythmia than amlodipine in EH patients complicated with arrhythmia .

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Influence of cardiac pacing at different sites on left atrial structure and function

Guangyu SU

Chinese Journal of cardiovascular Rehabilitation Medicine.2015;24(3):316-318. doi:10.3969/j.issn.1008-0074.2015.03.26

Objective:To explore the influence of cardiac pacing at different sites on left atrial structure and function . Methods:A total of 62 patients ,who needed cardiac pacing therapy because of bradycardia in our hospital from Jan 2012 to Jan 2014 ,were selected .According to the implanted sites of pacing electrode ,patients were equally divided into right ventricular cardiac apex group (RVA group) and right ventricular outflow tract group (RVOT group) . Left atrial volume before atrial contraction (LAVp) ,minimum left atrial volume (LAVmin) ,maximum left atrial volume (LAVmax) ,left atrial active emptying fraction (LAAEF) and left atrial passive emptying fraction (LA-PEF) etc .were compared between two groups before and after cardiac pacing therapy .Results:There were no sig-nificant difference in all indexes between two groups before treatment ,P>0.05 all .Compared with RVA group af-ter six-month pacing treatment ,there were significant reductions in LAVp [ (29.5 ± 3.2) ml vs .(27.1 ± 3.5) ml] , LAVmin [ (18.6 ± 2.0) ml vs . (17.2 ± 2.7) ml] ,LAVmax [ (48.9 ± 4.8) ml vs .(46.1 ± 5.1) ml] and LAAEF [(47.2 ± 4.5)% vs .(43.5 ± 4.2)% ] ,and significant rise in LAPEF [(40.9 ± 5.3)% vs .(43.6 ± 3.9)% ] in RVOT group ,P<0.05 or <0.01. Conclusion:Effect of right ventricular outflow tract pacing is more than that of right ventricular cardiac apex pacing and may be used as a replacement of right ventricular cardiac apex .

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Correlation among hypertension,hyperlipidemia, hyperglycemia and body mass index in aged people f rom communi ties

Rongjun HUANG

Chinese Journal of cardiovascular Rehabilitation Medicine.2015;24(3):260-263. doi:10.3969/j.issn.1008-0074.2015.03.10

Objective:To explore the correlation among hypertension ,hyperlipidemia ,hyperglycemia and body mass index (BMI) in aged people from communities .Methods:A total of 1463 community residents ,who received health exami-nation in our hospital from Jan 2010 to Dec 2012 ,were selected .According to BMI ,they were divided into normal group (n=651) ,overweight group (n=463) and obesity group (n=349) .Blood pressure ,blood glucose and blood lipids were measured and compared among all groups ,and their correlation with BMI were analyzed .Results:Compared with female group ,there were significant rise in detection rates of overweight&obesity (48.77% vs .60.33% ) ,hypertension (14.24%vs .30. 87% ) ,hyperlipidemia (10. 15% vs .30. 63% ) and hyperglycemia (6. 71% vs .12. 32% ) in male group , P<0. 01 all;compared with normal group ,there were significant rise in detection rates of hypertension (16.44% vs .27.43% vs . 33. 24% ) ,hyperlipidemia (9. 37% vs .28. 29% vs .37. 54% ) and hyperglycemia (4. 76% vs .12. 53% vs .16. 33% ) in o-verweight group and obesity group ,P<0.01 all;BMI was positively correlated with levels of blood pressure ,blood glucose and blood lipids (r=0.374 ,0.317 ,0.294 , P<0.01) .Conclusion:Body mass index is significantly positively correlated with hypertension ,hyperlipidemia and hyperglycemia .Body weight control possesses important significance for prevention and treatment of hypertension ,hyperlipidemia and hyperglycemia .

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Comparison of treadmill exercise test results in male smokers and non-smokers

Rong ZHOU ; Yu PENG ; Suming ZHANG

Chinese Journal of cardiovascular Rehabilitation Medicine.2015;24(3):258-260. doi:10.3969/j.issn.1008-0074.2015.03.09

Objective:To observe the difference of results of treadmill exercise test (TET) between male smokers and non-smokers .Methods:A total of 200 men with long-term smoking ≥20 cigarette per day were screened from outpatients and treated as smoking group .Another 200 men with similar age ,who didn’ t smoke at all ,were regarded as non-smoking control group (control group) .There were no medical history for hypertension ,hyperlipidemia ,diabetes ,and were nega-tive for electrocardiography and color echocardiography (exclude left ventricular hypertrophy etc .organic heart disease) in two groups .TET results and incidence rate of acute myocardial infarction (AMI) within two years were compared between two groups .Results:Compared with control group ,there were significant rise in TET positive rate (37. 5% vs .57. 5% , P<0.001) and incidence rate of AMI (8.5% vs .17.5% ,P=0.007) within two years in smoking group .Conclusion:Risk of suffering from coronary artery disease is more high in smokers among men .

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Value of social support rating scale using in patients with vasovagal syncope

Haojin REN ; Liyue WANG ; Jun YANG

Chinese Journal of cardiovascular Rehabilitation Medicine.2015;24(3):249-252. doi:10.3969/j.issn.1008-0074.2015.03.06

Objective:To explore the value of social support rating scale using in patients with vasovagal syncope (VVS) .Methods:Social support rating scale (SSRS) established by XIAO Shui-yuan was used .A total of 200 VVS patients were collected from inpatients and outpatients and they received social support status investigation ,another 100 normal people were collected from our physical examination center were regarded as control (normal control group) .Results:Compared with normal control group ,there were significant reductions in scores of each item and total score of social support [ (37.22 ± 9.15) scores vs .(33.50 ± 8.64) scores] in VVS group ,P<0.05 or <0.01 ;compared with male patients ,there were significant rise in scores of subjective support [ (17.63 ± 6.72) scores vs . (18.62 ± 7.56) scores] ,utilization of support [ (7.51 ± 2.26) scores vs .(8.92 ± 2.82) scores] and total social sup-port [(34.32 ± 10.61) scores vs .(36.79 ± 7.86) scores] ,and significant reduction in objective support score [(9.28 ± 4.15) scores vs .(8.37 ± 3.49) scores] in female patients , P<0.05 or <0.01;compared with middle-aged and aged group ,there were significant rise in scores of subjective support [ (17.08 ± 6.34) scores vs .(19.51 ± 6.73) scores] and total social support [(33.18 ± 10.74) scores vs .(36.87 ± 8.73) scores] ,and significant reduction in uti-lization of support score [ (8.47 ± 2.60) scores vs .(7.53 ± 1.95) scores] in young group ,P<0.05 or <0.01. Con-clusion:Social support assessment is help to perform individualized diagnosis and therapy for patients with vasovagal syncope ,and help to improve their quality of life .

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Pathogenesis of complicated acute lung injury after percutaneous coronary intervention

Yubo XIE ; Zhicheng FANG

Chinese Journal of cardiovascular Rehabilitation Medicine.2015;24(3):240-243. doi:10.3969/j.issn.1008-0074.2015.03.03

Objective:To explore causes of complicated acute lung injury (ALI) after percutaneous coronary interven-tion (PCI) .Methods:According to blood gas analysis and chest imaging examination ,a total of 175 patients under-going PCI were divided into ALI group (n=62) and non-ALI group (n=113) .High performance liquid chromatog-raphy was used to measure plasma concentrations of epinephrine (E) and norepinephrine (NE) during perioperative period .Plasma levels of interleukin-6 (IL-6) and procalcitonin (PCT) and chest CT imaging changes were meas-ured .Fluorescent immunoassay was used to measure plasma level of brain natriuretic peptide (BNP) to assess impact of cardiac function on ALI .Results:Compared with non-ALI group on 1d after PCI ,there were significant rise in plasma levels of NE [ (2.51 ± 0.31) nmol/L vs .(6.91 ± 0.39) nmol/L] and E [ (1.23 ± 0.11) nmol/L vs .(6.03 ± 0.37) nmol/L] ,P<0.01 all;and significant rise in plasma levels of IL-6 [ (119.81 ± 17.23) pg/ml vs .(252.28 ± 34.23) pg/ml] ,PCT [ (0.88 ± 0.01) pg/ml vs .(4.99 ± 0.87) pg/ml] and BNP [ (927.82 ± 89.72) pg/ml vs . (3936.55 ± 131.78) pg/ml] in ALI group (P<0.01 all) .Chest CT indicated that lung tissue inflammation was seri-ous .Conclusion:In patients undergoing percutaneous coronary intervention ,complicated acute lung injury is related to hyperactive sympathetic activity ,postoperative inflammation and heart function status etc .

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Treatment progress of hypertrophic cardiomyopathy

Liwen LIU ; Zhankui DU ; Xiaozeng WANG

Chinese Journal of cardiovascular Rehabilitation Medicine.2015;24(3):349-351. doi:10.3969/j.issn.1008-0074.2015.03.36

Hypertrophic cardiomyopathy (HCM) is featured by asymmetry myocardial hypertrophy ,mainly involves interventricular septum ,and its clinical manifestations are left ventricular dysfunction and arrhythmia .It′s thera-peutic methods include medication ,intervention ,surgery ,dual chamber pacemaker (DDD) treatment and implant-able cardioverter /defibrillator (ICD) treatment etc .This article made following overview on treatment progress of HCM .

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