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A new triterpene glycoside from the sea cucumber Colochirous anceps

Chinese Journal of Marine Drugs.2005;24(2):13-17.

Objective To search for triterpene glycoside with new structure. Methods We studied the sea cucumber Colochirous anceps belonging to the family cucumariidea with many chromatography methods and found a new sulfated triterpene glycoside, which structure was established by a combination of spectroscopic analysis (IR, UV, ESI-MS and 2D-NMR), chemical transformations and other chemical evidence. Results and Conclusion The new sulfated triterpene glycoside was isolated and named Colochiroside A (1) .

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Chemical composition of Porphyra haitanensis (Rhodophyta, Bangiales) in China

Chengliang XIE

Chinese Journal of Marine Drugs.2009;28(1):29-35.

Objective To analyze the chemical composition of Porphyra haitanensis cultivated in Fujian Province.Methods The contents of crude protein,carbohydrate,crude fat,ash,free amino acids,inorganic elements,chlorophyll a,carotenoid,phycoerythrin and phycocyanin of dried P.haitanensis were determined by routine analysis methods.Results It showed the contents of crude protein,carbohydrate,crude fat and ash of dried P.haitanensis were 34.88%～37.21%,46.86%～49.27%,1.68%～2.09%and 8.75%～9.92%.The contents of chlorophyll a,carotenoid,phycoerythrin and phycocyanin in P.haitanensis were 60 1～646,120～130,1289～1802,1255～1743mg(100g)-1.P.haitanensis is rich in free amino acids and inorganic elements,i.e.K,Na,Mg,Fe,P and Zn,but very little heavy metals,i.e.Cu,Cd and Cr.Conclusions The P.haitanensis was a kind of health food,which was in high content of protein,low content of fat and rich of inorganic elements.

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THE ISOLATION OF SEA EXTREME MICROORGANISMS AND THEIR POSSIBLE APPLICATIONS

Jinrui FANG ; Weizhen HUANG

Chinese Journal of Marine Drugs.1994;0(01):-.

Microorganisms isolated from the sea extreme condition have the potential to prqvide. diverse bioactive substances that are present to their metabolites. Organisms with pH optimal for growth in alkaline range and with temperature optimal for growth in lower temperature range are defines as alkalopsychrophilic microorganisms,which are one of rich resources of bioactive compounds for further stuties with both scientific interest and practical use.

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A SURVEY OF THE METHODS OF EXTRACTION, ISOLATION AND DETERMINATION FOR GLYCOSAMINOGLYCANS

Changyun WANG ; Huashi GUAN

Chinese Journal of Marine Drugs.1994;0(01):-.

The studies on glycosaminogiycans (GAG) from animals are carrying out extensively in the fields of biology.biochemistry and medicine. The methodology of GAG researches has been developed rapidly at present. The researches of GAG have just begun in China. Synthesizing a large number of references,this paper gives a brief introduction on the methods of extraction isolation and determination for GAG. And the latest methods and developing tendency are summarized as well.

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DISTRIBUTION OF SELENIUM ASSOCIATED WITH BIOCHEMICAL FRACTIONS IN BLUE MUSSEL AND BAY SCALLOP

Wenjun MAO ; Huashi GUAN

Chinese Journal of Marine Drugs.1994;0(01):-.

Concentration,biochemical fractions of selenium have been investigated in the tissue organs of Blue mussel ( Mytilus edulis ) and Bay scallop ( Argopecten trradiaus ). It is found by determination that the selenium concentration in the mantle is higher than in other tissue organs of the Blue mussel and Bay scallop. Selenium is predominantely associated with amino acids and proteins. 64. 4 per cents to 70. 4 per cents of selenium was associated with insoluble proteins in the mantle of the Blue mussel and Bay scallop.

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TNF-INDUCING ACTIVITY OF SEPIA IN MICE

Shen HE ; Changlong LU

Chinese Journal of Marine Drugs.1994;0(01):-.

TNF in sera from BALB/c mice treated with sepia was detected by L929 cell killing assay. Sera of the mice treated with saline were used as control. Results showed a significant TNF -inducing activity of sepia in animals. And the induced sera were also cytotoxic to human cancer cells,such as GM803 and Y99.

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CARBOXYLIC DERIVATIVES OF SUBERGORGIC ACID AND THEIR TOXICOLOGY

Yingcai PENG ; Zhongde WU ; Kanghou LONG

Chinese Journal of Marine Drugs.1994;0(01):-.

Six new sesquiterpenoid compounds of nerve-activity were synthesized from a gorgonian neurotoxin -subergorgic acid (1). Toxicological studies and structural correlation with toxicity reveal that subergorgic acid may act on cholinesterase and make a reversible inhibition of its activity of hydrolysis.

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ANALYSIS OF THE RESULT OF LAL TEST FOR PYROGEN OF 200 BATCHES OF INJECTIONS

Xuewen XUE

Chinese Journal of Marine Drugs.1994;0(02):-.

This paper deals with an. analysis of the result of LAL test for pyrogen of 200 batches injection. The result is reliable and shows that the operation of this method is easy, quick and sensitive.

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THE COMPREHENSIVE UTILIZATION OF WASTE EEL BONE FROM ROAST EEL

Meizhen CHEN ; Jie YU ; Gangzhe SHE

Chinese Journal of Marine Drugs.1994;0(02):-.

The contents of the components in waste eel bone from roast eel were determined. Optimal conditions for extracting eel bone oil from waste eel bone as raw material, purifing the polyunsaturated fatty acids (PUFA) concentrates from eel bone oil via salt-forming with urea complexation, and preparation of microcapsules containig PUFA concentrates from eel bone oil by spray drying were investigated systematically. The results showed that the technique was easy to carry out, the complete yield for extracting eel bone oil was above 76%, the contents of EPA and DHA in PUFA purified from eel bone oil increased from 7. 4% to about 45%, the recovery of EPA plus DHA was 64% , the content of PUFA from eel bone oil in the microcapsuls was about 26. 2%, and its antioxidative stability was higher than that of mixture of PUFA concentrates without capsulizing.

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A STUDY OF PSS THERAPY ON REFRACTORY NEPHROSIS IN CHILDREN

Wenli ZHOU ; Liyuan XU ; Xiuying WANG

Chinese Journal of Marine Drugs.1994;0(02):-.

The changes of the hemorheology, plasma cholesterol and albumin and clinicaleffects in 36 children with refractory nephrosis after treatment with polysaccharide sulfate (PSS) were observed. The results showed that the indices of hemorheology and the plasma cholesterol decreased obviously and the albumin increased obviously than the control group ( P

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