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POST-EXERCISE CHANGE OF THE QTC INTERVAL IN CORONARY HEART DISEASE

Yongan LI ; Yufeng LUO ; Chuanping ZHANG ;

Journal of Chongqing Medical University.1986;0(02):-.

The present study summarized the results of QTc. in 54 subjects, 8 of which were patients with coronary heart disease and 46 normal.The exercise tests were carried out on an ergometric bicycle with a submaximal exercise andQT interval was corrected for heart rate according to Bazett's formula (QTc=QT/R-R-). All patients were subjects to resting ECG before the test, during excerxise, and immediately fol owing the end of the exercise. Electrode jelly contact disk electrodes were used for the CMS. Results showed that coronary heart disease patients all had a prolongation of the QTc following exercise with variations of 0.06+0.02s The QTc of all normal subjects, except one, Showed a shortening or no ohange.Our study thus reveaded that the finding of QTc variations with exercise all of value for the diagnosis of coronary heart disease.

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THE PROTECTIVE ACTION OF PIPERITONE IN ANAPHYLACTIC SHOCK OF THE GOINEA--PIG

Gaoqin HE ; Yuzhu JIN ;

Journal of Chongqing Medical University.1986;0(02):-.

Forty-four guinea-pigs were sensitized by intramuscular inoculation with the same amount (0.8ml) of 5% egg albumin in water. 3 weeks after sensitization, the animals were rondomly divided into 1 groups (group J as control; group II given small dose of piperitone 0.08ml/ 100g body weight; group J given large dose of piperitone 0.12ml/100g body weight; group IX given promethazine 2.5mg 100g body weight) and subjected to anaphylactic insult by intra-cardiac injection of 1ml of 5% egg albumin in water under the protection of different dosege of piperitone, a terpene from cymbopogon distans. given intramuscularly. Results of the experiment indicates that piperitone had significant dose-effect relation protective effect against the anaphylactic insult on the guinea-pigs and suggests that piperitone might be used clinically for the treatment of asthma

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COMPARATIVE INVIVO OVICIDAL EFFECT OF ALBENDAZOLE AND MEBENDAZOLE ON HOOKWORM EGGS AND IN THE TREATMENT OF INTESTINAL NEMATODE INFECTIONS

Peng GAO ; Yuehan LIU ; Xiaogen WANG ; Qinan WANG ; Licongzhi ; Zhaobin GUO ; Qun SHU ;

Journal of Chongqing Medical University.1986;0(02):-.

Albendazole and mebendazole were comparatively evaluated in 22 adult patients for their in vivo effects on hookworm eggs. Both drugs were given 200mg twice daily for three consecutive days. Stool specimens wore collected before treatment and during the following five days. The Stool egg count was carried out by Stolls method and each specimen was also cultured by Hara-da-Mori technique for at least eight days. The mean pre-treatment percentage of incubated hookworm eggs that developed to larvae was 75.3% in albendazole group and 68.8% in mebendazole group respectively. One day following the initiation of treatment the mean percentage was remarkably reduced to 0.25% in albeadaole group and no eggs developed to larval stage beyond day 1. 0ne day and two days following the initiation of treatment the mean percentage was 16.23% and 23.13% respectively in mebendazole group. No eggs developed to larval stage on day 3 and thereafter. Albendazole seems to have better ovicidal effect than mebendazole.Albendazole and mebendazole were also comparatively evaluated in 123 adult patients with single or mixed infections of hookworm, ascarisis, and trichuris. A single dose of 400mg was used for both drugs. 2 and 4 weeks after treatment, their stools were examined by brine flotation technique. The hookworm eggs negative conversion ratss 2 weeks after treatment were 78.8% and 26.4% respectively in albeadazole and mebendazole group; while those 4 weeks after treatment were 74.1% and 25.5% respectivley. For ascariasis, the eggs negative conversion rates were 98.0% and 92.0% respectively. For trichuriasis, the negative conversion rates were only 20.6% and 27.7% respectively

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GLYCOSYLATED SERUM PROTEIN IN DIABETES MELLITUS

Zaoguo OU ; Shaochu SU ; Changda SHU ;

Journal of Chongqing Medical University.1986;0(03):-.

The concentration of glycosylated serum protein (GSP) in 125 normal subjects and 105 diabetic patients was measured. The result showed that the mean value of GSP in diabetic patients increased as compared with that of normal subjects, and the mean , concentration of GSP correlated significantly with that of fasting blood glucose in diabetic patients as well as that the mean value of fasting blood glucose which was determined 1-3 weeks before. The level of GSP may be a sensitive indicator for recent control of diabetes

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ANTIHYPERTENSIVE THERAPY AND INTRACELLULAR CATIONS

Yunzhen CHEN ; Han LEI ;

Journal of Chongqing Medical University.1986;0(03):-.

Thirty-seven essential hypertensive patients were treated with nifedipine and captopril. The effects of both drugs on high blood pressure and inteacellular cations were reported.A significant reduction in leucocyte Na concentration compared to the baseline were noted after therapy (P

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NEEDLE ASPIRATION FOR THE TREATMENT OF PERITONSILLAR ABSCESS

Xiaochuan LI ; Lequn WU ; Jialian WU ; Yonghong LIU ;

Journal of Chongqing Medical University.1986;0(02):-.

Forty-five patients with peritonsillar abscesses(PA) were treated by needle aspiration. Pus was drawn in 89%(40/45) of the cases at the first aspiration and repeated aspiration was necessary in 33%(15/45) of the patients. All of the patients were cured by needle aspiration without further invasive therapy and no serious complication was observed. 32 out of 45 patients were available for follow-up. Among them, three had another recurrent PA in situ and the other ten(31%) had recurrent tonsillitis. However, analysis showed that the patients under 35 years of age had higher recurreuce rate of PA of recurrent tonsillitis than those over 35 years old(P

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THE DIAGNOSIS AND TREATMENT OF ADULTS CASES WITH FOREIGN BODIES IN THE ALIMENTARY TRACT

Zhengjia LIU ;

Journal of Chongqing Medical University.1986;0(02):-.

Three hundred and two cases of foreign bodies in the alimentary tract of adults treated in the First Hospital of the Chongqing University of Medical Sciences from 1958 to 1986 were analyzed with reference to the varietes and forms of the foreign bodies, their routes and ways of entrance into the alimentary tract and their clinical manifestations. Importance of early diagnosis and opportune treatment is emphasized. For detecting on transparent or semitransparent foreign bodies under fluro-scopy, the swallowed cotton fibers with barium emulsion waS found of help. Management of the cases depends on the condition of the foreign bodies. Early operation is of importance in cases of incarceration of the foreign bodies so as to prevent serious complications

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DETECTING THE HAEMODYNAMIC EFFECTS OF PREMATURE SYSTOLES WITH IMPEDANCE CARDIOGRAMS

Yongan LI ; Yunzhen CHEN ; Rongzhong WANG ; Chuanping ZHANG ;

Journal of Chongqing Medical University.1986;0(02):-.

0.05). The average SV of premature systoles is 35% of sinus beats. Premature systoles less than 5 beats/min may cause and average drop of 5% of cardiac output (CO), While the premature systoles increased to 10-20 beats/min, the CO would be dropped further of 10-19%. there Was a high linear correlation between sr of all premature systoles and the coupling interval premature systoles (p

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SERUM MONOAMINE OXIDASE ISOENZYME DETERMINATION——A PRELIMINARY EVALUATION IN THE DIAGNOSIS OF LIVER DISEASES

Daohong CHEN ; Dingming SHEN ;

Journal of Chongqing Medical University.1986;0(02):-.

Suerm monoamine oxidasa isoenzymes (MAOi) were determined in 105 cases of liver disea ses and 49 normal controls.MAOi were separated into 3 bands (I. Ⅱ.Ⅲ) by polyacrylamide gel elcctrophoresis. The results revealed that MAOi Ⅲ% was increased in chronic liver diseases, especially in liver cirrhosis. Our findings suggest that serum MAOi determination is more sensitive than serum albumin, MAO, ChE, and ADA determinationsin in the early diagnosis of liver cirrhosis

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THE CLINICAL SIGNIFICANCE OF ECHOCARDIOGRAPHIC DIAGNOSIS OF AORTA-SEPTAL ANGLE VARIANCE:AN ANALYSIS OF 307 CASES

Zhigang WANG ; Dewang LI ; Shuzhen DING ; Shiyu PU ; Lei SHI ;

Journal of Chongqing Medical University.1986;0(03):-.

An statistical analysis of aorta-septal angle(AS angle) between anterior wall of aorta and ventricular septum was taken,AS angle was measured fromthe right ventricle with long-axis, two-dimensional echocardiongram of the left ventricle in 227 consecutive cases of patients with cardiovascular diseases and 80 healthy adults since 1985. It was found that AS angle for normal adults at the end of systoie(ES) and the end of diastole(ED) being 118.50?? 7.70? and 110.60??8.23?; the difference between ES and ED was 7.89??4.51?. In patients with overburdening of left ventricular volume and resistance of coronary artery disease, car-diomycpathy and hypertension , AS angles were amaller,and in patients with overburdening of right ventricular pressure of rheumatic mitral stenosis, AS angles were larger than healthy adults. The difference between ES and ED was smaller than normal for all patients. It was also found that in patients with heartdisease AS angle tends to be smaller or larger before the appearance of abnormality of the left ventricular cavity. Our data suggested that AS angle variance might afford some clinical significance of diagnosis

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