Epiphrenic Esophageal Diverticulum
Chonnam Medical Journal.2023;59(2):142-142. doi:10.4068/cmj.2023.59.2.142
Chonnam Medical Journal
1964 to Present ISSN: 2233-7385
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Superior Sagittal Sinus Thrombosis in Chronic Liver Disease
Chonnam Medical Journal.2023;59(2):141-141. doi:10.4068/cmj.2023.59.2.141
Vomiting Associated with Rapid Weight Loss
Chonnam Medical Journal.2023;59(2):140-140. doi:10.4068/cmj.2023.59.2.140
Chonnam Medical Journal.2023;59(2):134-139. doi:10.4068/cmj.2023.59.2.134
This study examined the gender-specific association between stroke status and depression in South Korea. A total of 5,746 men and 7,608 women aged ≥30 years who participated in the 2014, 2016, and 2018 Korea National Health and Nutrition Examination Survey were included in the analysis. The cross-sectional surveys targeted the general population consisting of nationally representative adults (≥19 years) residing in Korea. A 9-item Patient Health Questionnaire score of 10 or more was regarded as depression. A higher risk of depression in stroke survivors compared to the non-stroke population was not observed in men (odds ratio [OR], 1.51; 95% confidence intervals [CI], 0.82-2.81), while it was observed in women (OR, 2.49; 95% CI, 1.64-3.77). Compared to non-stroke women, women stroke survivors with a younger age at diagnosis (＜60 years) (OR, 4.05; 95% CI, 2.28-7.20) and stroke with duration of ≥10 years (OR, 3.12; 95% CI, 1.63-5.97) had a higher risk for depression. Gender aspects should be more intensively considered in the association between stroke status and depression in community settings.
Urban-Rural Differences in the Prevalence of Depressive Symptoms in Korean Adults
Chonnam Medical Journal.2023;59(2):128-133. doi:10.4068/cmj.2023.59.2.128
This study aimed to investigate the prevalence of depression among Koreans living in urban and rural areas, stratified by socioeconomic status. The study included 216,765 participants from the 2017 Korean Community Health Survey. Depressive symptoms were assessed using the PHQ-9, with a score of 10 or higher indicating depressive symptoms. Residences with the words Eup and Myeon in their addresses were categorized as rural areas, and residences with Dong in their addresses as urban areas. Socioeconomic status was evaluated by household income and education level. A Poisson regression analysis with sampling weights was conducted and adjusted for demographic, lifestyle, socioeconomic status, and comorbidity. The adjusted prevalence rate of depressive symptoms was 3.33% (95% CI, 3.21-3.45) in urban areas and 2.59% (95% CI, 2.43-2.74) in rural areas. The prevalence of depressive symptoms in urban areas was 1.29 times (95% CI, 1.20-1.38) higher than in rural areas. The prevalence rate ratio for depressive symptoms in urban areas compared to rural areas sorted by monthly incomes was 1.39 (95% CI, 1.28-1.51) for less than 2 million won, 1.22 (95% CI, 1.06-1.41) for 2 to 3.99 million won, and 1.09 (95% CI, 0.90-1.32) for more than 4 million won, and the urban-rural difference was more evident in lower household income subjects (p for interaction=0.033). However, urban-rural differences did not differ according to sex, age, or education level. In conclusion, we found urban-rural differences in depressive symptoms in a representative sample of Koreans, and revealed that these differences may vary according to income level. These results suggest that mental health policy must consider the health disparities according to residence and income.
Adverse Effects Associated with Long-Term Use of Proton Pump Inhibitors
Chonnam Medical Journal.2023;59(2):115-127. doi:10.4068/cmj.2023.59.2.115
Proton Pump Inhibitors are used widely to manage many gastric acid-related conditions such as gastroesophageal disease, gastritis, esophagitis, Barrett’s esophagus, Zollinger-Ellison syndrome, peptic ulcer disease, nonsteroidal anti-inflammatory drug-associated ulcers, and Helicobacter pylori eradication, around the globe. This review article focuses on adverse effects associated with the long-term use of proton pump inhibitors. Various observational studies, clinical trials, and meta-analyses have established the adverse effects associated with the long-term use of proton pump inhibitors including renal disorders (acute interstitial nephritis, acute kidney injury, chronic kidney disease, and end-stage renal disease), cardiovascular risks (major adverse cardiovascular events, myocardial infarction, stent thrombosis, and stroke), fractures, infections (Clostridium difficile infection, community-acquired pneumonia, and Coronavirus disease 2019), micronutrient deficiencies (hypomagnesemia, anemia, vitamin B12 deficiency, hypocalcemia, hypokalemia), hypergastrinemia, cancers (gastric cancer, pancreatic cancer, colorectal cancer, hepatic cancer), hepatic encephalopathy, and dementia. Clinicians including prescribers and pharmacists should be aware of the adverse effects of taking proton pump inhibitors for an extended period of time.In addition, the patients taking proton pump inhibitors for long-term should be monitored for the listed adverse effects. The American Gastroenterological association recommends a few non-pharmacological measures and the use of histamine 2 blockers to lessen gastrointestinal symptoms of gastroesophageal reflex disease and the utilization of proton pump inhibitors treatment if there is a definitive indication.Additionally, the American Gastroenterological association’s Best Practice Advice statements emphasize deprescribing when there is no clear indication for proton pump inhibitors therapy.
Diabetic Pedal Osteomyelitis and Its Treatment
Chonnam Medical Journal.2023;59(2):109-114. doi:10.4068/cmj.2023.59.2.109
Diabetes is a fast-growing chronic metabolic disorder that is widely associated with foot ulcers. The major challenge among these ulcers is wound infections, altered inflammatory responses, and a lack of angiogenesis that can complicate limb amputation.The foot, because of its architecture, becomes the part most prone to complications and the infection rate is higher mainly between the toes due to the humid nature. Therefore, the infection rate is significantly higher. Wound healing in diabetes is a dynamic process usually delayed due to poor immune function. Diabetes-related pedal neuropathy and perfusion disturbances can lead to a loss of sensation in the foot. This neuropathy can further be a risk factor for ulcer development due to repetitive mechanical stress that later might get infected by the invasion of microorganisms extending to the bone and causing an infection called pedal osteomyelitis. This review details the pathophysiology, the biomaterials aiding in the infection cure and regeneration of bone along with their limitations, as well as their future prospects.
Primary Cardiac Angiosarcoma in a Patient with Syncope:A Case Report
Chonnam Medical Journal.2023;59(3):211-212. doi:10.4068/cmj.2023.59.3.211
Chonnam Medical Journal.2023;59(3):209-210. doi:10.4068/cmj.2023.59.3.209
Eggshell Calcification in Progressive Constrictive Pericarditis
Chonnam Medical Journal.2023;59(3):207-208. doi:10.4068/cmj.2023.59.3.207
Country
Republic of Korea
Publisher
Chonnam National University Research Institute of Medical Science
ElectronicLinks
http://cmj.ac.kr/Editor-in-chief
Soo Wan Kim
curims@chonnam.ac.kr
Abbreviation
Chonnam Med J
Vernacular Journal Title
전남의대학술지
ISSN
2233-7385
EISSN
2233-7393
Year Approved
2007
Current Indexing Status
Currently Indexed
Start Year
1964
Description
Chonnam Medical Journal is a peer-reviewed open access journal published 3 times per year in English. The Journal aims to promote the exchange of scientific information generated from basic science and clinical research. The Journal publishes original and review articles, commentary, and case reports in the fields of clinical and experimental medicine. Special features include videos and images in clinical medicine. The scope of Chonnam Medical Journal covers: cell and structural biology, cancer and stem cells, neuroscience, infection and immunology, circulation and hemodynamics, metabolism, and surgery.
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