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Applications of IVUS in Modern PCI Procedure

Journal of Kunming Medical University.2013;(8):160-165.

Intravascular ultrasound (IVUS) is a commonly used technology in percutaneous coronary intervention (PCI) procedure. It has higher resolution and repeatability, and more importantly, it can make the vascular structure visiable which shows the plaque morphology and component, compared with traditional coronary angiography. Most researches indicated that IVUS can help doctors find out the optimized stent size, stent malapposition,stent disexpansion,and procedure complication, thus reduce the incidence of restenosis and stent thrombosis. IVUS has been widely applied in research about the predictors of PCI complication, these results benefit us to make better decision on PCI procedure. In this article, we reviewed the studies based on IVUS technology during the last 10 years and summrized according to restenosiss and stent thrombosis with BMS (bare metal stent) and DES (drug eluting stent) .

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The Progress in the Application of PCNA in Head and Neck Cancer

Zhimin SUN ; Xiaojiang LI

Journal of Kunming Medical University.2013;(8):157-159.

Tumor cell proliferation activity is related with tumor biological behavior. PCNA (proliferating cell unclear antigen, PCNA) is a kind of histone nucleoprotein, is associated with cell proliferation and DNA synthesis,can reflect the degree of cell proliferation and cycle period, it is as a cell proliferation activity indicator, has been widely used in a variety of tumor research,the expression of PCNA in common head and neck tumor can be used as the biological behaviour and prognosis judgement.

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Special Training of Postgraduates Majored in General Surgery

Yujian ZENG ; Huayou LUO

Journal of Kunming Medical University.2013;(8):153-156.

Objective To discuss how to improve the cultivation level of postgraduates majored in general surgery by special training.Methods We retrospectively analysed the work performance of 78 postgraduates in the first year after graduated from the general surgery of our hospital during 2005 to 2009. The employer’s evaluation of the postgraduates was compared between before and after special training.Results 22 postgraduates didn’ t receive special training,and 56 postgraduates receive special training. The clinical skills and clinical thinking ability of the postgraduates received special training were much better than the postgraduates who didn’ t receive special training, there was a significant difference between two groups ( P<0.05 ) . Conclusion The special training can significantly improve the clinical skills and clinical thinking ability of the postgraduates majored in general surgery in our hospital.

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Investigation on the Prevalence of Xerostomia in 200 AIDS Patients

Kunli WU ; Guanglan MA ; Lian XUE

Journal of Kunming Medical University.2013;(8):144-146.

Objective To investigate the incidence of xerostomia in patients with acquired immune deficiency syndromes (AIDS), clarify the association between AIDS and xerostomia to promote AIDS patients' oral health. Method The oral health conditions of 200 hospitalized AIDS patients were investigated by a self-designed evaluation form. Results Among 200 patients, xerostomia occurred in 113 (56.6%) . Among the xerostomia patients, 32.7% were without brushing habits, 63.7% with long-term medication and 43.1% (31 cases) with mainly antibiotics, antivirals and antifungal drugs. 30 (31.9%) patients with xerostomia were mainly associated with symptoms of oral burning, lips dry and scaly, periodontitis, oral mucosal dryness and tooth loss. Conclusions AIDS could increase the incidence of xerostomia. Some effective measures should be taken to promote patients' oral health, including improving AIDS patients' awareness of oral health, close observation of adverse reactions after treatment,looking for related causes, timely and targeted therapies,early detection and treatment of associated symptoms.

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Diagnosis,Treatment and Prognosis of Sinonasal Neuroendocrine Carcinoma

Chaowu JIANG ; Yuping NA ; Min GUO ; Jinya WEN ; Ben LIU

Journal of Kunming Medical University.2013;(8):125-128.

Objective To study the diagnosis and treatment of neuroendocrine carcinoma of the nasal cavity and paranasal sinuses, and analyse the influencing factors of suvival and prognosis. Methods We retrospectively analyzed the diagnosis and treatment process of 14 patients with sinonasal neuroendocrine carcinoma (SNEC) admitted in The First Affiliated Hospital of Kunming Medical University from 2007 to 2011. All patients were followed up to learn the survival status of them.Results All patients were followed up for one year up to six years except 2 patients who gave up treatment. Five patients died and six survived with good tumor control in the followed up period. Two patients received only endoscopy surgery, and one of them died from lung metastasis in 21 months after operation, and the other one survived with good tumor control, the disease free survival (DFS) was 9 months . Eight patients were treated by endscopy surgery and /or chemo-radiotherapy, three cases died in following-up period, and five of them survivied with good tumor control, and the disease free survival was 20.25 months.Two patients with transcatheter arterial infusion chemotherapy survivied with good tumor control within the follow up period,and the DFS was 25.5 months.Five patients had moderately differentiated SNEC and DFS was 25.5 months. Seven patients had poorly differentiated SNEC with DFS 14.6 months. Six patients were T4N0M0, four patients were T3N0M0, two patients T2N0M0, and their DFS were 19 months, 12.8 months and 33 month, respectively. Conclusions Surgery with radiotherapy and/or chemotherapy is the current treatment method for sinonasal neuroendocrine carcinoma. Small cell neuroendocrine carcinoma with poor differiation displays highly aggressive and poor prognosis. Diagnosis and treatment in early stage is important for good prognosis.

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Application of Early Rehabilitation Treatment in Functional Improvement after Total Knee Arthroplasty

Dongmei GAO

Journal of Kunming Medical University.2013;(8):95-97.

Objective To investigate the effect of early rehabilitation treatment on functional improvement after total knee arthroplasty. Methods 48 patients (53knees) of rehabilitation in our hospital from 2010 to 2013 were divided into 2 groups, 22 patients (25knees) in control group were given common rehabilitation training, 26 patients (28 knees) in observation group were given early rehabilitation treatment. Results All the ROM, knee score and function score of 2 groups were improved, and observation group were better than that of control group (P<0.05),at the last follow-up, the PF, BP and VT of observation group were better than control group (P<0.05) . Conclusion Early rehabilitation treatment can significantly promote the knee function recovery after surgery and improve the life quality of patients, so it deserves to be generalized.

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Experiences in Diagnosis and Treatment of Seventy Eight Patients with Scrotum Gangrene in Uganda

Lei WANG ; Lijun WANG ; Yiming ZHONG ; Haidon QIAN

Journal of Kunming Medical University.2013;(8):117-119.

Objective To study the diagnosis, treatment, etiology and prognosis of scrotum gangrene. Method We did a retrospective analysis of the data of 78 patients with scrotum gangrene who hospitalized during August 2007 and August 2011 in Jinja Hospital in Uganda.Results Among 78 patients, 73 patients were cured, with 93.6%of the cure rate. After early debridement and second phase reconstruction, patients recovered after the treatment. Conclusion On the basis of systemic antibiotic drug use and local debridement processing, penis-scrotum revascularization has good curative effect on scrotum gangrene.We hope to provide reference and help to foreign health medical team of aid work in Yunnan province.

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The Value of Neutrophil to Lymphocyte Ratio in Predicting In-stent Restenosis in Patients with Coronary Heart Disease

Liguo ZHANG ; Youming ZHANG ; Bin JIAN ; Zhuo YU

Journal of Kunming Medical University.2013;(8):114-116.

Objective To investigate the value of neutrophil to lymphocyte ratio (NLR) in predicting in-stent restenosis (ISR) in patients with coronary heart disease. Methods We collected the data of 618 patients with coronary heart disease hospitalized in the Department of Cardiology in the First Affiliated Hospital of Kunming Medical University from January 2011 to June 2012. All selected patients underwent coronary angiography and stent implantation, and were divided into two groups according to the average size of NLR. The relationship between the neutrophil to lymphocyte ratio and coronary heart disease in-stent restenosis was investigated. Results There were statistically significant differences in the presence of diabetes, high density lipoprotein, low density lipoprotein, the percentage of neutrophils and lymphocytes in patients between two groups (P<0.05) . We found 13 patients (4.2%) and 32 patients (10.4%) with in-stent restenosis in the first group and the second group, respectively, and there was a statistically significant difference between two groups (P<0.01) . Conclusion Neutrophil to lymphocyte ratio is correlated with ISR,and has clinical value in predicting ISR.

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Clinical Observation on Endoscopic Treatment of Ureteral Calculi Acute Obstruction with Urinary Extravasation

Guibin MA ; Qiong SUN ; Xingze XU ; Haoyang HE ; Liyu LI ; Zhixing TAO ; Weisheng WANG

Journal of Kunming Medical University.2013;(8):107-109.

Objective To investigate the feasibility and safety of endoscopic treatment of ureteral calculi acute obstruction with urinary extravasation. Methods 56 patients with ureteral calculi acute obstruction and urinary extravasation were randomly divided into two groups:the treatment group and the control group,28 cases in each group. Patients in the treatment group were given URSL or percutaneous nephrostomy drainage, and the secondary fistula was given URSL stone clearance treatment. Patients in control group were given traditional ureterolithotomy treatment. The stone clearance rate, the average recovery time after surgery, postoperative wound infection rate and the abnormal rate of postoperative albumin were observed in two groups. Results In the treatment group,28 patients had no residual stones with mean postoperative recovery time of (5.2 1.3) days,postoperative fever was found in 3 cases,obvious abnormal postoperative albumin in 3 cases. In the control group,residual stones were found in 3 cases,the average recovery time after surgery was (7.9 2.6) days,postoperative fever was found in 10 cases, and obvious abnormal postoperative albumin in 11 cases. There were statistically significant differences in stone clearance rate, the average recovery time after surgery, postoperative wound infection rate and the abnormal rate of postoperative albumin between two groups (P<0.05) . Conclusion Endoscopic treatment of ureteral calculi acute obstruction and urinary extravasation has advantages including better efficacy, less trauma, less complications and quicker recovery.

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The Clinical Significance of DSA and MRA Detection in Cerebrovascular Disease of Patients with Diabetes Mellitus

Mingli ZHOU ; Jun FENG

Journal of Kunming Medical University.2013;(8):88-91.

Objective To explore the clinical significance of DSA and MRA detection in cerebrovascular desease of patients with diabetes mellitus.Methods 142 diabetic patients were selected in the study. The vascular structure was detected by digital subtraction angiography (DSA) and magnetic resonance angiography (MRA) . Results There was 1123 (56.5%) branches of artery atherosclerotic stenosis in a total of 1988 detecting artery and there was no significant difference between the DSA and MRA (χ2=0.36、0.47、0.53,P>0.05) . The results showed that the DSA and MRA methods had no significant difference on display average count in detecting bilateral ACA,MCA,PCA 284 vessels (t=0.27、0.56、0.89,P>0.05) . There were 656 arteries stenosis in checking the Willis ring vascular by DSA evaluation of the Willis ring and the sensitivity and specificity by MRA were more than 90%. Conclusion MRA and DSA can be applied in diagnosis of in cerebrovascular disease of patients with diabetes mellitus.The noninvasive advantages of MRA are worth to be concerned by clinician.

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