Journal of Kunming Medical University 2013;(8):157-159

The Progress in the Application of PCNA in Head and Neck Cancer

Zhimin SUN ; Xiaojiang LI

Keywords

PCNA; Head and neck cancer; Progress

Country

China

Language

Chinese

Abstract

Tumor cell proliferation activity is related with tumor biological behavior. PCNA (proliferating cell unclear antigen, PCNA) is a kind of histone nucleoprotein, is associated with cell proliferation and DNA synthesis,can reflect the degree of cell proliferation and cycle period, it is as a cell proliferation activity indicator, has been widely used in a variety of tumor research,the expression of PCNA in common head and neck tumor can be used as the biological behaviour and prognosis judgement.