In the past 30 years since its inception, the Chinese Journal of Behavioral Medicine and Brain Science has been constantly pragmatic and innovative, and adhered to the implementation of a series of strong journal plans.The editors taken the construction of high-quality scientific and technological journals as an opportunity, the Chinese Journal of Behavioral Medicine and Brain Science focuses on improving the core competitiveness of journals, expanding the international influence of journals, strengthening the digital construction of journals and improving editor ability to create high-quality scientific and technological journals.It has achieved fruitful results.In the future, the Chinese Journal of Behavioral Medicine and Brain Science will continue to adhere to the principle of " academic first, quality first" , grasp the implementation of the " China Brain Plan" and " Healthy China Action" , adhere to integrity and innovation, continue to create a brand of journals with higher academic influence, and further drive the development of disciplines.

Objective:To analyze the characteristics of papers on Chinese Journal of Behavioral Medicine and Brain Science based on F5000, so as to provide reference for topic selection planning, soliciting contributions, soliciting contributions and mining high-quality manuscript sources.Methods:The papers selected from Chinese Journal of Behavioral Medicine and Brain Science from 2012 to 2019 were selected as the research objects.The paper magazine published by Chinese Journal of Behavioral Medicine and Brain Science and Wanfang database were used as information sources.The selected year, publication year, fund distribution, high publishing provinces and institutions, and cited frequency were statistically analyzed.Results:From 2012 to 2019, F5000 collected 79 papers in Chinese Journal of behavioral medicine and brain science, which published in 2007-2018.The percentage of fund papers was 82.27%, the percentage of national fund papers was 37.97%, and the average number of fund projects was 1.58.The high produced institutions were concentrated in Jiangsu, Shandong, Chongqing, Shanxi and Beijing.The ratio of cooperation in institutions was 53.2%.The ratio of cooperation in authors was 96.20%.The number of citations was 1 253 , and the average number of citations per article was 15.86.The total citation frequency was 2 404, and the average citation frequency per article was 30.43.Seventy-one articles were included to analyse the key words.The total number of key words was 293, and the average number of keywords per article was 4.13.It mainly focused on emotional disorders, cognitive function, psychological assessment, brain function and structure.Conclusions:Chinese Journal of Behavioral Medicine and Brain Science is relatively stable in terms of fund paper ratio, ratio of cooperation in authors and core author team.It is necessary to further tap the core authors, promote multi-disciplinary and field cooperation, strive for excellent author resources and manuscript resources, so as to improve the core competitiveness of the magazine.

Objective: To analyze the trend of citation index of Chinese Journal of Behavioral Medicine and Brain Sciences(CJBMBS) from 2011 to 2018, and compare to the average level of Chinese Medical Association(CMA) series journals, so as to provide basis for improving academic quality and journal influence. Methods: Trend analysis on citation index of CJBMBS from 2011 to 2018 and comparison with the average level of Chinese Medical Association series journals were conducted by Microsoft Excel 2010. Results: From 2011 to 2018, the core impact factor(0.849-1.151) and ratio of foundation-supported papers(0.550-0.810) of CJBMBS showed an upward trend, while the core total citation(1 783-2 836) showed a downward trend.The core total citation, core impact factor and ratio of foundation-supported papers of CJBMBS were higher than the average level of CMA series journals(1 355-1 699, 0.497-0.890, 0.335-0.460), but the core other-citation rate was lower than the average level of CMA series journals (0.81-0.85). Conclusion The CJBMBS is at a high level among the core journals of Chinese science and technology, and more attention should be paid to the problem of high self-citation rate.

Cerebrovascular disease,Alzheimer's disease,Parkinson's disease and other chronic encephalopathy has become a worldwide public health problem.Cognitive impairment,including mild cognitive impairment to dementia,is closely related to chronic encephalopathy,especially cerebrovascular diseases.Early detection,early diagnosis,early treatment of cognitive impairment has become the focus of the research,in order to reduce the development of dementia,improve the quality of life and reduce the burden of disease.This article elaborates the research progress of cognitive impairment from the aspects of pathological mechanisms,risk factors,clinical diagnosis and strategy prevention and control,and the arguments of domestic experts.

To analyze the mortality risk of stroke in China by literature search.The mortality rate of stroke (age standardized) in China has declined in recent years.The mortality rate of stroke which increases with age is higher in rural areas than in urban areas,and is higher in men than in women in China.There are obvious regional differences and seasonal differences in the mortality of stroke in China.Different subtypes of stroke have different death characteristics.Low or high temperatures can increase the risk of mortality of stroke.With the change of epidemiological characteristics,the risk factors of mortality of stroke in China are also changing.Through the epidemiological study of stroke death,the mortality risk of stroke can be researched effectively,the epidemiological characteristics of stroke can be mastered,and the direction of prevention and treatment of stroke can be understood.Individualized and multi factor intervention for unhealthy lifestyle,unhealthy behavior and metabolic cardiovascular risk factors can promote the establishment of stroke prevention and control strategy in China.

Post-stroke aphasia is an acquired language disorder caused by stroke.It impaired the quality of life of patients and brought a heavy burden to family and the society.Unfortunately,the highly variable predictive factors make the prognosis of aphasia recovery difficult.Much of the researches indicated that the post-stroke aphasia recovery is associated with the patient-related and stroke-related factors.We searched the recent advances on the influence of patient-related factors and stroke-related factors on aphasia recovery.It showed that patient-related factors have no obvious effect on predicting aphasia recovery while the lesion (stroke)-related factors appeared close correlation with post-stroke aphasia recovery.The clinicians should pay more attention on lesion (stroke)-related factors when evaluate the outcome and give the intervention measures.

Objective To investigate the effect of the 5-hydroxytryptamine (5-HT) on the occurrence,development of post-stroke depression (PSD).Methods The literatures on the relationship between 5-HT and PSD were selected from databases such as Wanfang Data,CNKI and PubMed before in 2010-2014.According to absorption and exclusion criteria of the literature,collect literatures,and summary,induce and analyze on them.Results Search 258 literatures and accept 44 literatures accorded with the criteria,including the relationship between 5-HT and PSD,the relationship between 5-hydroxytryptamine receptor (5-HTR) gene polymorphism and PSD,the relationship between 5-hydroxytryptamine transporter linked promoter region (5-HTTLPR) and PSD,and the treatment of selective serotonin reuptake inhibitors (SSRIs) in PSD.Conclusion Reduced levels of 5-HT lead to the occurrence of PSD,and they had a negative correlation;5-HTR 1 A,5-HTR2A are related genes of PSD;S allele and S/S genotype is susceptible factors of PSD,while the L allele is the protective factors of PSD;SSRIs can increase the level of 5-HT in the synaptic gap so as to improve the depressive symptoms of PSD.In the future,it is necessary to increase the sample size to confirm the relationship between 5-HT and PSD,and combine with other factors to explore the relationship between them.

Objective To analyze the papers published in Journal of Chinese Behavioral Medicine and Brain Science(JCBMBS) from 2009 to 2014 so as to know well of the characteristics of published papers and the progress of the journal.Methods Based on the published magazines,Wanfang database and the Magtech system,bibliometric analysis was conducted to analyze the quantity,types,authors,cooperation,citations and the funds of all the papers published from 2009 to 2014.Results A total of 2 343 papers were published from 2009 to 2014 with the average 390.50 items per year,32.54 items per tissue and 0.34 items per page.It was stable in columns setting and publishing types while the original papers accounted for more than 70％ every year.Zero fund-supported papers decreased year by year and the funds were 1.41-1.83 per article while the ratio of national funds supported papers were 20％-31％.It had a steady author group and the high produced institutions maintained stable.The ratio of cooperation in institutions were 45％-58％.The ratio cooperation in authors were 95.45％-97.09％ and it was high and steady.The citations were 12.45-18.48 per article which increased year by year.Conclusion From 2009 to 2014,the annual published articles on JCBMBS decrease,the paper density decreases and the citations increase year by year.It is relatively steady in columns setting,core authors,ratio of fund-supported papers and cooperation.

Objective To analyze the articles and authors published in Journal of Chinese Behavioral Medicine and Brain Science(JCBMBS) in 2012.Methods By using the bibliometric statistical methods,all papers published in JCBMBS in the whole year of 2012 were analyzed,including the paper amount,the paper column,the published style of papers,the institute distributions and the area distributions of the first authors,the foundation supported papers amount,the author amount,the citation amount and the published delay.Results 375 papers were published in JCBMBS in 2012,31.25 papers were published in an average issue,and one article included 3.06 pages averagely.The paper density was 0.327 and the information density was 5.21.The main style of published papers was original article,which accounted for 79.7％,and the least style was experts forum articles,which accounted for 2.4％.The amount of clinical research articles were 129,the hygienic articles were 89 and the basic research articles were 80.The area distributions of the first author were wide and imbalance.The top 6 provinces of the most published paper amounts in 2012 were Shandong,Jiangsu,Guangdong,Beijing,Anhui and Henan,where published paper amounts in total were 207 papers,and accounted for 55.2％ of the total papers of the whole year.There were 244 articles supported by various foundations and accounted for 65.06％ of the total papers of the whole year,in which 30.93％ was supported by the national foundations.The average author amount of the published papers,the average citation amount and the average published delay were 4.71 authors,15.58 indexes and 161.5 days respectively.12 corresponding authors had published 3 or more than 3 articles,and 37 corresponding authors had published 2 articles in the year.The top fifteen institutes of the most paper amounts in the periodical had published 145 articles,accounting for 38.7％ of the total amount of the papers.Conclusion The JCBMBS have an aboundant information resource;the main style of the published papers is original article;the clinical researches are the most in all columns.There are higher foundation supported papers and steady authors of this periodical.

Objective To further investigate the relationship between apolipoprotein E(APOE) genotype and trait anxiety in patients with coronary heart disease (CHD).Methods Use the state-trait anxiety inventory (STAI) to investigate the state anxiety and trait anxiety of 107 CHD patients.According the score of TAI,the CHD patients were divided into CHD with high trait anxiety group ( n=39)and low trait anxiety group(n=68).The genotypes and alleles of apolipoprotein E gene was detected in all CHD patients and 50 healthy control subjects with the polymerase reaction(PCR) and restriction fragment length polymorphisms(RFLP) technique.Correlation analysis and logistic regression analysis were used.Results Apolipoprotein E gene showed positive relationship with trait anxiety score( OR =9.251,95％ CI2.726 ～ 18.266).F4 allele entered the regression equaltion Y =30.252 + 0.048X3 (P ＜ 0.05 ).Conclusion The results suggest the polymorphisms of Apolipoprotein E e4 allele may be associated with the trait anxiety symptom.