1.Analysis on the medication rules of Pu Ji Fang for treating acne externally based on data mining
Yisheng ZHANG ; Jundong ZHANG ; Xue LI ; Xinyuan LIU ; Jianan YANG ; Zongyou LI ; Ping SONG
International Journal of Traditional Chinese Medicine 2023;45(2):208-213
Objective:To analyze the medication rules in the ancient book Pu Ji Fang for the external treatment of acne based on data mining method. Methods:By screening out the methods of treating acne externally in Pu Ji Fang and establishing a standardized medical record database, this paper adopted the web version of Ancient and Modern Medical Record Cloud Platform to calculate the frequency, properties, flavors, and meridians of those medicines, and conduct cluster analysis by using IBM SPSS Modeler 18.0 software to analyze the association rules. Results:A total of 87 prescriptions were selected, including 164 kinds of Chinese materia medica, among which. Radix Angelicae, Ligusticum Wallichii, Rhizoma Typhoni and lead powder are frequently appeared. The properties of those medicines are mainly warm, cold and mild; the flavors of those medicines are mainly spicy, acrid, sweet and bitter, and the meridians mainly belongs to lung, spleen, stomach and liver meridians. The medical pair and group with the strongest associationion are Ligusticum Wallichii- Radix Angelicae and Rhizoma Typhonii- Radix Angelicae- Ligusticum Wallichii. Those freuently appeared medicines could be grouped into three categories. The paste dosage that was frequently appeared has strong correlation with tallow, mercury and lead powder, while the powder dosage that was frequenctly appeared has strong correlation with Angelica Dahurica, Radix Saponicae, Gleditsia sinensis, Radices Ligustici Sinensis and Ligusticum Wallichii. Conclusions:The application of data mining method could preliminarily reveal the medication rules of Pu Ji Fang for the external treatment of acne. The main treatment method is XinSanFaYue. The three categories of Chinese materia medica are used to treat the syndrome of asthenic habitus attacked by exogenous pathogenic factors, exterior attacked by wind heat and hot blood stasis respectively, showing the rules of treating acne externally before Ming Dynasty and providing references for the clinical treatment of acne.
2. Analysis of traditional Chinese medicine treatment of asthma from different syndrome based on literature
Nong TANG ; Zongyou LI ; Li KANG ; Shuo YANG ; Lei LEI
International Journal of Traditional Chinese Medicine 2019;41(12):1370-1374
Objective:
To explore the rules of TCM treatment of Asthma on different syndromes.
Methods:
We searched the modern clinical literature of asthma treated by TCM form Chinese Clinical Literature Database, SinoMed, CNKI, Wanfang Database and CQVIP from 1949-2017, collected key information such as diseases, syndromes, and drug composition by human-computer integration and constructed a database. We calculated the co-occurrence matrix of syndrome-herb and the frequent item sets of herb for different syndromes using TCM Miner (http://tcmminer.cintcm.com:8023/tcm/index.jsp). The prescription and treatment of asthma with different syndrome were analyzed, and a new medicine prescription was proposed for common five kinds of common syndromes.
Results:
There were 234 articles containing 124 syllables, 1 337 prescriptions and 290 herbs. For different syndromes, the high-frequency medicine was obviously different, which reflected the important ideas of TCM syndrome differentiation. According to five common syndromes including fever syndrome, cold syndrome, lung-spleen qi deficiency syndrome and kidney-yang deficiency syndrome, five new drug prescriptions have evolved.
Conclusions
Analysis of TCM prescriptions based on differentiating syndromes can explore the essence of TCM and provided ideas and data support for researchers.
3.Analysis on the current status of the resource and service of traditional Korean medicine
Yanmin HU ; Jun XU ; Zongyou LI ; Haiyu LI ; Wei JIANG ; Yang ZHAO ; Yanwen LI
International Journal of Traditional Chinese Medicine 2019;41(1):1-4
To explore the development tendency and major influential factors of traditional Korean medicine (TKM) resource and service by statistics analysis. Data are mainly from the Yearbook of Traditional Korean Medicine (2009-2015). Ministry of Health and Welfare Statistical Yearbook 2016, and the Ministry of health and welfare practicing qualification management system. This article analyzed the related indicators, such as the average annual growth rates and the proportion in the national medical system. From 2006 to 2015, the average annual growth rate of the number of TKM hospital and TKM clinics were 7.0% and 3.2% separately; the average annual growth rate of TKM doctor and TKM pharmacists were 4.3% and 10.0% separately; the average annual growth rate of the number of beds in TKM institutions were 9.3%; and the average annual growth rate of the number of applications for outpatient and inpatient reimbursement for medical insurance of TKM institutions were 12.3% and 20.5% separately. From 2006 to 2015, the resources and services of TKM presented an increasing tendency, and the accessibility of TKM resource and service was enhanced. It is suggested that China should use reference from the aspects of strengthening policy, expanding the sources of capital investment, and expanding the coverage of medical insurance.
4.The analysis and thoughts on traditional Chinese medicine international cooperation projects between China Academy of Chinese Medical Sciences and Europe
Zongyou LI ; Zhaoyuan JIANG ; Wei JIANG ; Ping SONG ; Longhui YANG
International Journal of Traditional Chinese Medicine 2018;40(11):1008-1010
The paper analysed the scale,character,cooperation countries,funds and achievements of the traditional Chinese medicine (TCM) international projects between China Academy of Chinese Medical Sciences (CACMS) and Europe from 2007-2017.The results showed that there were 44 projects between CACMS and Europe;the number of Chinese medicine,clinical and basic research projects were 21,9 and 6 respectively;the number of projects between CACMS and Austria,and between CACMS and Gemany were 20 and 8 respectively;the funds from Ministry of Science and Technology and CACMS accounted for relatively high proportions.Trough these projects between CACMS and Europe,the TCM centers were established,the key technologies were introduced,and the professionals were trained.But there were still some questions such as the regional maldistribution of cooperation countries,few acupuncture research,and little project funds.
5.Analysis and study on current status of European students in traditional Chinese medicine colleges and universities
Zongyou LI ; Wei JIANG ; Zijun ZHANG ; Ping SONG ; Longhui YANG
International Journal of Traditional Chinese Medicine 2018;40(12):1109-1112
The paper analyzed the scale, educational background, degree, and financial source of the European students in Chinese TCM colleges and universities by using excel 2013. The results showed that there were 19 TCM colleges and universities recruiting European students, and the number of campus students, enrollment students, graduation students were 409, 257 and 280 in 2017 respectively. The campus students in 2017 was highest since five years ago, but was less than the Afro-Asia states. Training was main form of studying abroad. Most campus students were at their own expenses, or received the help from Chinese government. The education for European students in Chinese TCM colleges and universities has made some achievement, but there were still some questions: the European students was not too much, the education's attraction was not strong, and the financial help from international organization and foreign government was scarce.
6.Comparison of medial and lateral locking plates for Schatzker type Ⅵ fractures of tibial plateau: a finite element analysis
Zongyou YANG ; Xiaodong CHENG ; Lian ZHU ; Bo WANG ; Zhanle ZHENG ; Wei CHEN ; Changping ZHAO ; Yingze ZHANG
Chinese Journal of Orthopaedic Trauma 2018;20(2):157-161
Objective To compare the biomechanical characteristics of medial and lateral locking plates for Schatzker typeⅥfractures of tibial plateau by finite element analysis. Methods A 38 year-old male volunteer was enrolled for CT scan of his lower limbs. His CT images of the left tibial plateau were used for 3D reconstruction of a model of Schatzker type Ⅵ fracture by NX 9.0 software. After the boundary con-ditions were set, a 500 N load was applied to the tibial plateau to simulate the stress on a single leg when an adult weighing 60 kg walked. The displacement and stress on plate and screws were analyzed by Abaqus software. Results The ultimate stress on the model fixated with a medial locking plate was 81.7 MPa, located at the proximal tibiofibular joint surface. The ultimate stress on the model fixated with a lateral locking plate was 487.4 MPa, located at the junction of plate and screws. The ultimate stress on the fibula was much larger in the model fixated with a medial locking plate than in the model fixated with a lateral locking plate. The ultimate displacement was smaller and more homogeneous in the model fixated with a medial locking plate (1.15 mm) than in the model fixated with a lateral locking plate (3.44 mm).Conclusion The Schatzker type Ⅵ fractures of tibial plateau should be fixated with a medial locking plate because it has more biomechanical advantages than a lateral locking plate.
7.Epidemiological comparison of adult pelvic fractures between West China and East China from 2010 to 2011
Guang YANG ; Wei CHEN ; Yiyang YU ; Xiao CHEN ; Bo LIU ; Shilun LI ; Ye TIAN ; Fei ZHANG ; Song LIU ; Zongyou YANG ; Lei LIU ; Jiayuan SUN ; Yingze ZHANG
Chinese Journal of Orthopaedic Trauma 2018;20(3):242-246
Objective To compare and analyze the epidemiological features of adult pelvic fractures between West China and East China from 2010 to 2011.Methods The data of adult pelvic fractures treated from January 2010 to December 2011 in 63 hospitals in West China and East China were collected through the PACS system and case reports checking system.The data from the 35 hospitals in East China were assigned into group A and those from the 28 hospitals in West China into group B.The analytic items included gender,age,age distribution and type of AO classification.Results A total of 7,896 cases were collected.In group A of 5,683 cases,there were 2,829 males and 2,854 females,with a male to female ratio of 0.99∶1 and a median age of 42 years (interquartile range,from 30 to 55 years).In group B of 2,213 cases,there were 1,123 males and 1,090 females,with a male to female ratio of 1.03∶1 and a median age of 41 years (interquartile range,from 31 to 54 years).There was no significant difference in the male to female ratio between the 2 groups (x2 =0.594,P =0.441) but there was a significant difference in the median age (Z =-4.344,P =0.000).The age distribution showed that the peak range was from 31 to 40 years in group A (with a proportion of 21.50%) and from 41 to 50 years in group B (with a proportion of 23.41%),showing no significant difference between the 2 groups (P > 0.05).In both groups,type 61-A was the high risk type of fracture (82.23% in group A and 86.08% in group B),and type 61-A2 the high risk subtype of fracture (41.47% in group A and 54.36% in group B),showing significant differences (P < 0.05).Conclusions East China and West China had similar male to female ratios in pelvic fractures.Generally,the patients in West China were younger,for the most patients in East China were aged from 31 to 40 years and those in West China from 41 to 50 years.In both East China and West China,type 61-A2 and subtype 61-A2 were the most common,but the proportions of type 61-A2 and subtype 61-A2 were higher in West China than in East China.
8.Epidemiological survey of scapular neck fractures between the east and west areas in China from 2010 through 2011
Lei LIU ; Zongyou YANG ; Jiayuan SUN ; Ran SUN ; Tao ZHANG ; Xiaodong CHENG ; Yanjiang YANG ; Wei CHEN ; Bing YIN ; Song LIU ; Shilun LI ; Yingze ZHANG
Chinese Journal of Orthopaedic Trauma 2018;20(9):787-791
Objective To compare the epidemiological characteristics of scapular neck fracture between the east and west areas in China from 2010 through 2011.Methods Tbe data of scapular neck fractures treated between January 2010 and December 2011 at 35 east hospitals and 28 west ones were analyzed retrospectively.The patients' gender,age and Miller classification were documented.The data from the 35 east hospitals were classified as group A while the data from the 28 west ones as group B.Comparisons were made to find out the general epidemiological characteristics.Results A total of 584 scapular neck fractures were collected.The total male/female ratio was 3.46∶ 1.The scapular neck fractures predominated in an age range from 41 to 50 years (25.17%).According to the Miller classification,there were 150 cases (25.68%) of type Ⅰ,306 ones (52.40%) of type Ⅱ and 128 ones (21.92%) of type Ⅲ.426 cases (72.95%) were stable fractures and 158 ones (27.05%) unstable fractures.The male/female ratio was 3.64∶1 in group A of 427 patients and 3.03∶1 in group B of 157 patients.There were no significant differences between the 2 groups in male/female ratio (P > 0.05).The median age of group A (44 years) was significantly older than that of group B (39 years).The fractures predominated in an age range from 41 to 50 years (24.36%) in group A and in the age range from 31 to 40 years (36.31%) in group B.The most frequent fracture type was type Ⅱ in both groups,accounting for 51.52% and 54.78% respectively.There were no significant differences between the 2 groups in distribution of Miller classification (P > 0.05).Conclusions The peak age of scapular neck fractures was from 41 to 50 years,the high-risk type was Miller type Ⅱ and stable fractures were more common.There were more male patients than female ones.The median age in the east area was older than that in the west area.
9.Epidemiological survey of glenoid fractures between the east and west areas in China from 2010 through 2011
Lei LIU ; Zongyou YANG ; Jiayuan SUN ; Ran SUN ; Tao ZHANG ; Xiaodong CHENG ; Yanjiang YANG ; Wei CHEN ; Bing YIN ; Song LIU ; Shilun LI ; Yingze ZHANG
Chinese Journal of Orthopaedic Trauma 2018;20(10):901-905
Objective To compare the epidemiological characteristics of glenoid fractures between the east and west areas in China from 2010 through 2011.Methods The data of glenoid fractures treated between January 2010 and December 2011 at 35 east hospitals and 28 west ones in China were analyzed retrospectively.The patients' gender,age and type of Ideberg classification were documented.The data from the 35 east hospitals were classified as group A while those from the 28 west ones as group B.Comparisons were made to find out the general epidemiological characteristics.Results A total of 347 glenoid fractures were collected.The total male/female ratio was 2.69∶ 1.The glenoid fractures predominated in 2 age ranges from 41 to 50 years and from 51 to 60 years (19.60%).According to the Ideberg classification,there were 75 cases (21.61%) of type Ⅰ,152 ones (43.80%) of type Ⅱ,27 ones (7.78%) of type Ⅲ,20 ones (5.76%) of type Ⅳ,46 ones (13.26%) of type Ⅴ and 27 ones (7.78%) of type Ⅵ.The male/female ratio was 2.80∶1 in group A of 228 patients and 2.50∶1 in group B of 119 patients.The median age of group A was 47 years old and that of group B 44 years old.The differences were not statistically significant in male/female ratio,median age or distribution of age between the 2 groups (P > 0.05).The fractures predominated in the age range from 51 to 60 years old (23.68%) in group A and in the age range from 31 to 40 years old (21.85%) in group B.The most frequent fracture type was type Ⅱin both groups,accounting for 41.23% and 48.74% respectively.There was a significant difference between the 2 groups in distribution of Ideberg classification (P < 0.05).Conclusions The peak age of glenoid fractures was from 41 to 60 years,the high-risk type was Ideberg type Ⅱ and there were more male patients than female ones.The proportion of Ideberg type Ⅴ in the east area was higher than that in the west area.
10.Exploration on the general laws of development of traditional Chinese medicine academic
Aijun LI ; Zongyou LI ; Yinghui WANG ; Yanmin HU ; Wei JIANG ; Yang ZHAO ; Lin WANG ; Yanwen LI
International Journal of Traditional Chinese Medicine 2017;39(10):865-868
Base on literature analysis, the paper summarized that the five core principles of the traditional Chinese medicine academic development included that the practice is the source of traditional Chinese medicine development, the culture is the foundation of traditional Chinese medicine development, the inheritance is the basic approach of traditional Chinese medicine development, the classics is the important carrier of traditional Chinese medicine development, and the innovation is the power of traditional Chinese medicine development.

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