Objective: This study was devoted to identifying natural thrombin inhibitors from traditional Chinese medicine (TCM) and evaluating its biological activity in vitro and binding characteristics. Methods: A combination strategy containing molecular docking, thrombin inhibition assay, surface plasmon resonance (SPR) and molecular dynamics simulation were applied to verify the study result. Results: Gallic acid was confirmed as a direct thrombin inhibitor with IC

From 2000 to 2004, the National Natural Science Foundation of China (NSFC) accepted 1 171 applications and funded 160 projects for fundamental research on integrated traditional Chinese and Western medicine. The success rate is 13.64%. Being supported by NSFC, a number of achievements well known in China and abroad have been made, such as acupuncture complementary anaesthesia, treatment of leukemia, viral hepatitis, cardio-cerebrovascular diseases, acute abdomen, burns and fracture with integrated traditional Chinese and Western medicine and their therapeutic mechanisms, and some new concepts and theories have been put forward, such as the theories of activating blood to resolve stagnation, simultaneous treatment of bacteria and toxin, etc. But there still exit some problems in the research of the funded projects. The research ways are mainly combination of different methods instead of integration of both traditional Chinese and Western medicine. The research results are mainly confirmation of traditional Chinese medical theories instead of exploration of their innate regularities. The relationship among disease, syndrome and symptom is not clearly explored. The principal-subordinate relationship between macro- and micro-differentiation of syndromes is not clear. Academic research is short of new ideas. Improper or biased explanation of the theories of traditional Chinese medicine still exists. On analysis of above problems, some preferable aspects of projects for fundamental research on integrated traditional Chinese and Western medicine funded by NSFC in future are suggested in this article.

This paper develops the field medical information management system,which realizes the informationiztion and team service management for field medical team.system to field medical team. It also provides interface program with No.1 Military Medical Project,which realizes the linking of medical treatment information about patient in field medical team and rear military hospital.

The hospital information system(HIS)is processed in digital standardization for information sharing.In this way,all medical information in different hospitals can be compiled and compared,which provides sufficient and reliable information for the fundamental research on public health and medicine.

Objective To develop Department-level Cost Accounting System based on No.1 Military Medical Project.Methods Making the full use of programs and data in No.1 Military Medical Project,the software creates department income from the lists of outpatient fee and inpatient fee,and then in combination with the consumable disbursement,equipment depreciation,realty depreciation and maintaining cost etc,the software collects and sums up all income and cost to create cost accounting report forms.Results Department-level Cost Accounting System could automatically create the cost-accounting report forms for hospital management.Conclusion The application of Department-level Cost Accounting System strengthens the management of cost accounting in military hospitals and achieves good effect.

The operating principle of pulse blood oxygen saturation monitor is introduced. The usage and maintenance are discussed. Notice in using the instrument is suggested. The problem that the SPO2 detector is easy to damage is solved.

The field medical team is a constituent of military hospital and its informatization facilitates the management of the personnel and material as well as command and tele-consultation.When the field medical team informatized,wireless network,medical information management and the interface with the rear hospital should be emphasized on to make information share available.

This paper studies the objective and significance of field medical team,and discusses in detail the content of medical informatization from the patients' arrival at field medical team to their delivery to hospitals,as well as the long-distance support,the hardware support and the prospect of medical informatization.

This paper develops such auxiliary programs of the outpatient service subsystem of No.1 Military Medical Project as registration program and charge query program of nondrug outpatient service. These programs improve the charge system of outpatient service.

The informatization of the realty management for barracks of the military hospital is fulfilled based on No.1 Military Medical Project, and thus the interacting management of barracks can be performed by the administration and the departments together.