1.Development of alpha-glucosidase inhibitor from medicinal herbs.
Fang JI ; Guochun XIAO ; Li DONG ; Zijiao MA ; Jingman NI
China Journal of Chinese Materia Medica 2010;35(12):1633-1640
		                        		
		                        			
		                        			Alpha-glucosidase inhibitor can reduce the postprandial hyperglycemia and have good effect on preventing and treating the diabetes and diabetic complication. Along with the application of acarbose which is a kind of alpha-glucosidase inhibitor, many research groups pay attention to the crude alpha-glucosidase inhibitor screened from the medicinal herbs in order to find new, safe, and effective medicine. The development of alpha-glucosidase inhibitor screened from the medicinal herbs and its evaluation in vivo and vitro as well as the varieties of the medicinal herbs that contain alpha-glucosidase inhibitor in recent 30 years were summarized in this paper.
		                        		
		                        		
		                        		
		                        			Cell Line
		                        			;
		                        		
		                        			Drug Evaluation, Preclinical
		                        			;
		                        		
		                        			Enzyme Inhibitors
		                        			;
		                        		
		                        			isolation & purification
		                        			;
		                        		
		                        			pharmacology
		                        			;
		                        		
		                        			Glycoside Hydrolase Inhibitors
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Plant Extracts
		                        			;
		                        		
		                        			isolation & purification
		                        			;
		                        		
		                        			pharmacology
		                        			;
		                        		
		                        			Plants, Medicinal
		                        			;
		                        		
		                        			chemistry
		                        			
		                        		
		                        	
            
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