Objective To discuss the role of clinical pharmacist in individualized treatment and pharmaceutical care for a patient with Pneumocystis jiroveci pneumonia after renal transplantation. Methods The clinical pharmacist participated in the pharmaceutical care for a patient with Pneumocystis jiroveci pneumonia after renal transplantation. the literature were reviewed and analyzed and the medication of anti-infective treatment plan was adjusted by Clinical pharmacist. The adverse reactions in the treatment process were discovered in time, and corresponding treatments were made. Results Clinical pharmacists assisted physicians to adjust the medication plan and the patient recovered well after the treatment. Conclusion Clinical pharmacists could assist doctors in discovering drug treatment-related problems by mastering relevant treatment guidelines, the effectiveness and safety characteristics of drugs, which could help to establish individualized treatment plans and improve the safety and effectiveness of patients' medication.