1.Scoping review of prone position ventilation in pediatric patients with hypoxemia following extracorporeal cardiac surgery
Hui JIANG ; Xiaoling BAI ; Zhongsha CHENG ; Zengzhen YANG ; Qing WEI
Chinese Journal of Modern Nursing 2023;29(35):4876-4881
		                        		
		                        			
		                        			Objective:To systematically review the application of prone position ventilation in pediatric patients with hypoxemia following extracorporeal cardiac surgery.Methods:A scoping review methodology was adopted. Databases including PubMed, Embase, Web of Science, Cochrane Library, CINHAL, CBM, CNKI, Wanfang, and VIP were searched for relevant studies on the use of prone position ventilation in pediatric patients post-extracorporeal cardiac surgery. The search was conducted from the establishment of the databases until August 31, 2022. After literature screening and data extraction, research results were summarized.Results:Nine studies were ultimately included. Intervening factors in the application process of prone position ventilation included intervention timing, head-of-bed elevation angle, frequency and duration, and pediatric patient positioning. All nine studies reported positive outcomes; three articles reported associated complications.Conclusions:The timing of intervention, the angle of head-of-bed elevation, frequency and duration, patient positioning of prone position ventilation in pediatric patients with hypoxemia after extracorporeal cardiac surgery have not yet been standardized. Future high-quality research is required to further explore these intervention factors, offering references for the standardized and effective clinical application of prone position ventilation.
		                        		
		                        		
		                        		
		                        	
2.Clinical features and transfusion effectiveness of patients with hematological diseases underwent acute transfusion reactions
Li WANG ; Yu ZOU ; Wenzhu CHEN ; Zengzhen WEI ; Chunyan HUANG ; Li QIN ; Bin TAN
Chinese Journal of Blood Transfusion 2021;34(4):354-358
		                        		
		                        			
		                        			【Objective】 To demonstrate the real incidence and clinical features of acute transfusion reactions (ATRs) and analyze its association with transfusion effectiveness. 【Methods】 The blood transfusion process of patients in the Hematology Department in our hospital from March 16, 2018 to March 16, 2019 was observed and followed up. The vital signs and clinical features were recorded, the clinical data and relevant laboratory examination results were collected, and the correlation between ATRs, clinical features and transfusion effectiveness was statistically analyzed. 【Results】 A total of 2500 transfusions were observed in the Hematology Department, out of which 138 patients developed 242 ATRs. The overall incidence of ATRs was 9.68% (95% CI, 8.52%~10.94%) and the incidence of ATRs during platelets transfusion was the highest. The clinical features of most ATRs were mild and no fatal consequences occurred. No significant difference was found in the association between transfusion effectiveness with ATRs in platelets and red blood cells transfusion (P>0.05). 【Conclusion】 None of the ATRs observed in this study resulted in serious consequences or had effect on the transfusion effectiveness. The characteristics presented in these reactions may provide certain references for clinical practice.
		                        		
		                        		
		                        		
		                        	
            
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