1.Association of dairy intake frequency with left ventricular hypertrophy in childhood
Zilin LI ; Yanqing ZHANG ; Qian ZHANG ; Chuanwei MA ; Min ZHAO ; Bo XI
Chinese Journal of Preventive Medicine 2020;54(12):1389-1395
Objective:To examine the association between dairy intake frequency and left ventricular hypertrophy(LVH) in childhood.Methods:Data were obtained from Huantai Childhood Cardiovascular Health Cohort study in Huantai County, Zibo City, Shandong Province. A convenient cluster sampling method was used to conduct a baseline survey on 1 515 children aged 6-11 years old in a primary school from November 2017 to January 2018. A total of 1 237 children who had complete data on questionnaire, physical, ultrasound and laboratory examinations were included for analysis. The frequency of dairy intake was divided into five groups (never,≤3 times/month, 1-2 times/week, 3-5 times/week and nearly every day). Multivariate linear regression models and chi-square trend test were used to examine the trend in level of LVMI and prevalence of LVH, respectively. With the increase of dairy intake frequency, and multivariate logistic regression models were used to evaluate the association between dairy intake frequencies and LVH in childhood.Results:The age of children was (8.4±1.6) years, and the number of boys was 655 (53.0%). There was no significant difference in LVMI levels among different frequencies of dairy intake ( P>0.05). With the increase of dairy intake frequencies, the level of LVMI and the prevalence of LVH decreased significantly ( P for trend<0.05). After the adjustment of potential covariates, compared with no dairy intake group, children who consumed dairy products 1-2 times/week ( OR=0.27, 95% CI:0.09-0.82), 3-5 times/week ( OR=0.33, 95% CI:0.12-0.91) and almost every day ( OR=0.22, 95% CI:0.09-0.54) had a lower risk of LVH. Conclusion:Dairy intake frequency is associated with LVH in childhood, and children who consume dairy products frequently (more than once a week) are less likely to have LVH.
2.Association of dairy intake frequency with left ventricular hypertrophy in childhood
Zilin LI ; Yanqing ZHANG ; Qian ZHANG ; Chuanwei MA ; Min ZHAO ; Bo XI
Chinese Journal of Preventive Medicine 2020;54(12):1389-1395
Objective:To examine the association between dairy intake frequency and left ventricular hypertrophy(LVH) in childhood.Methods:Data were obtained from Huantai Childhood Cardiovascular Health Cohort study in Huantai County, Zibo City, Shandong Province. A convenient cluster sampling method was used to conduct a baseline survey on 1 515 children aged 6-11 years old in a primary school from November 2017 to January 2018. A total of 1 237 children who had complete data on questionnaire, physical, ultrasound and laboratory examinations were included for analysis. The frequency of dairy intake was divided into five groups (never,≤3 times/month, 1-2 times/week, 3-5 times/week and nearly every day). Multivariate linear regression models and chi-square trend test were used to examine the trend in level of LVMI and prevalence of LVH, respectively. With the increase of dairy intake frequency, and multivariate logistic regression models were used to evaluate the association between dairy intake frequencies and LVH in childhood.Results:The age of children was (8.4±1.6) years, and the number of boys was 655 (53.0%). There was no significant difference in LVMI levels among different frequencies of dairy intake ( P>0.05). With the increase of dairy intake frequencies, the level of LVMI and the prevalence of LVH decreased significantly ( P for trend<0.05). After the adjustment of potential covariates, compared with no dairy intake group, children who consumed dairy products 1-2 times/week ( OR=0.27, 95% CI:0.09-0.82), 3-5 times/week ( OR=0.33, 95% CI:0.12-0.91) and almost every day ( OR=0.22, 95% CI:0.09-0.54) had a lower risk of LVH. Conclusion:Dairy intake frequency is associated with LVH in childhood, and children who consume dairy products frequently (more than once a week) are less likely to have LVH.
3.The effects of overweight and obesity on left ventricular hypertrophy among hypertensive school-aged children
ZHANG Qian, MA Chuanwei, XI Bo
Chinese Journal of School Health 2019;40(6):815-817
Objective:
To examine the influences of overweight and obesity on left ventricular hypertrophy (LVH) in school-aged children, and to provide the scientific reference for early screening and making interventional measures for the damage of their heart structure.
Methods:
Based on a cross-sectional survey conducted in Jinan between 2012 and 2014, a total of 327 students aged 6-17 who had hypertension were selected. Covariance analysis and trend chi-square test were used to analyze the trend of left ventricular mass index (LVMI) and abnormal LVH rate across different categories of body mass index (BMI) after adjusted for age, gender and blood pressure (BP). Logistic regression analysis was used to evaluate the effects of overweight and obesity on LVH.
Results:
After adjusting for age, gender and BP, covariance analysis indicated that with the increase of BMI, the levels of LVMI [(26.8±1.8, 34.7±1.5, 40.1±0.9)g/m2.7] and prevalence of LVH (80.%, 22.4%, 41.4%) showed upward trends (F/χ2=22.68, 24.28, P<0.05). Compared with normal weight school-aged children, the risk of LVH increased for overweight and obese school-aged children, and the odds ratios (95% confidence intervals) were 3.83 (1.16-12.61) and 9.18 (3.10-27.19), respectively.
Conclusion
Overweight and obesity significantly increase the risk of LVH in school-aged children. Effective prevention and treatment of overweight and obesity may reduce the risk of abnormal cardiac structure in school-aged children.


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