1.Evaluation of simultaneous tandem drainage of intra-abdominal abscesses caused by gastrointestinal anastomotic failure
Yutaka UENO ; Shuji KARIYA ; Miyuki NAKATANI ; Yasuyuki ONO ; Takuji MARUYAMA ; Yuki TANAKA ; Kanji SUGIURA ; Noboru TANIGAWA
International Journal of Gastrointestinal Intervention 2025;14(2):71-76
Background:
This study aimed to demonstrate the effectiveness of a percutaneous method for treating intra-abdominal abscesses caused by gastrointestinal anastomotic leakage using tandem catheter placement for simultaneous drainage.
Methods:
This retrospective study involved 12 patients with intra-abdominal abscesses from anastomotic leakage who underwent image-guided percutaneous drainage. In the tandem drainage technique, one or more catheters were inserted into the abscess while an additional catheter was advanced into the gastrointestinal tract through the anastomotic dehiscence to decompress the tract and prevent further leakage. The study evaluated the technical and clinical success rates of this approach.
Results:
Technical success was achieved in nine of 12 patients (75.0%), with clinical success in eight of these nine patients (88.9%). The mean overall drainage duration after tandem placement was 65.0 days (range, 6–154 days), and the mean hospitalization duration for patients with clinical success was 66.7 days (range, 10–156 days).
Conclusion
Simultaneous tandem drainage is a feasible treatment for intra-abdominal abscesses caused by anastomotic leakage and may be a viable option for patients who are not candidates for surgery.
2.Potential of 6-mm-diameter fully covered self-expandable metal stents for unresectable malignant distal biliary obstruction: a propensity score-matched study
Daiki YAMASHIGE ; Susumu HIJIOKA ; Yoshikuni NAGASHIO ; Yuta MARUKI ; Soma FUKUDA ; Shin YAGI ; Kohei OKAMOTO ; Hidenobu HARA ; Yuya HAGIWARA ; Daiki AGARIE ; Tetsuro TAKASAKI ; Akihiro OHBA ; Shunsuke KONDO ; Chigusa MORIZANE ; Hideki UENO ; Miyuki SONE ; Yutaka SAITO ; Takuji OKUSAKA
Clinical Endoscopy 2025;58(1):121-133
Background/Aims:
To date, only thinner-diameter metal stents have been evaluated for unresectable malignant distal biliary obstruction (UR-MDBO). This study investigated the outcomes and optimal cohorts for a 6-mm-diameter fully covered self-expandable metal stent (FCSEMS) compared with those for a 10-mm-diameter FCSEMS.
Methods:
This single-center retrospective cohort study included patients who underwent initial transpapillary metal stenting for UR-MDBO. Propensity score matching (1:1) analysis was performed.
Results:
Of 133/68 patients who underwent 6-mm/10-mm-diameter FCSEMS deployment, 59 in each group were selected. The median time to recurrent biliary obstruction was not significantly different between the groups (p=0.46). In contrast, use of the 6-mm-diameter FCSEMS resulted in a significantly reduced incidence of stent-related adverse events (AEs) (p=0.016), especially cholecystitis (p=0.032), and patients aged <70 years were particularly affected by this significant reduction. Among the patients in the end-stage cohort who were unable to continue chemotherapy after FCSEMS deployment, the free rate of stent-related events, including recurrent biliary obstruction and stent-related AEs, was significantly higher in the 6-mm group (p=0.027).
Conclusions
For UR-MDBO, a 6-mm-diameter FCSEMS can be an optimal and safe option in the younger cohort with a relatively high risk of AEs and in the end-stage cohort requiring safer drainage without interference from stent-related events during times of poor prognosis.
3.Potential of 6-mm-diameter fully covered self-expandable metal stents for unresectable malignant distal biliary obstruction: a propensity score-matched study
Daiki YAMASHIGE ; Susumu HIJIOKA ; Yoshikuni NAGASHIO ; Yuta MARUKI ; Soma FUKUDA ; Shin YAGI ; Kohei OKAMOTO ; Hidenobu HARA ; Yuya HAGIWARA ; Daiki AGARIE ; Tetsuro TAKASAKI ; Akihiro OHBA ; Shunsuke KONDO ; Chigusa MORIZANE ; Hideki UENO ; Miyuki SONE ; Yutaka SAITO ; Takuji OKUSAKA
Clinical Endoscopy 2025;58(1):121-133
Background/Aims:
To date, only thinner-diameter metal stents have been evaluated for unresectable malignant distal biliary obstruction (UR-MDBO). This study investigated the outcomes and optimal cohorts for a 6-mm-diameter fully covered self-expandable metal stent (FCSEMS) compared with those for a 10-mm-diameter FCSEMS.
Methods:
This single-center retrospective cohort study included patients who underwent initial transpapillary metal stenting for UR-MDBO. Propensity score matching (1:1) analysis was performed.
Results:
Of 133/68 patients who underwent 6-mm/10-mm-diameter FCSEMS deployment, 59 in each group were selected. The median time to recurrent biliary obstruction was not significantly different between the groups (p=0.46). In contrast, use of the 6-mm-diameter FCSEMS resulted in a significantly reduced incidence of stent-related adverse events (AEs) (p=0.016), especially cholecystitis (p=0.032), and patients aged <70 years were particularly affected by this significant reduction. Among the patients in the end-stage cohort who were unable to continue chemotherapy after FCSEMS deployment, the free rate of stent-related events, including recurrent biliary obstruction and stent-related AEs, was significantly higher in the 6-mm group (p=0.027).
Conclusions
For UR-MDBO, a 6-mm-diameter FCSEMS can be an optimal and safe option in the younger cohort with a relatively high risk of AEs and in the end-stage cohort requiring safer drainage without interference from stent-related events during times of poor prognosis.
4.Evaluation of simultaneous tandem drainage of intra-abdominal abscesses caused by gastrointestinal anastomotic failure
Yutaka UENO ; Shuji KARIYA ; Miyuki NAKATANI ; Yasuyuki ONO ; Takuji MARUYAMA ; Yuki TANAKA ; Kanji SUGIURA ; Noboru TANIGAWA
International Journal of Gastrointestinal Intervention 2025;14(2):71-76
Background:
This study aimed to demonstrate the effectiveness of a percutaneous method for treating intra-abdominal abscesses caused by gastrointestinal anastomotic leakage using tandem catheter placement for simultaneous drainage.
Methods:
This retrospective study involved 12 patients with intra-abdominal abscesses from anastomotic leakage who underwent image-guided percutaneous drainage. In the tandem drainage technique, one or more catheters were inserted into the abscess while an additional catheter was advanced into the gastrointestinal tract through the anastomotic dehiscence to decompress the tract and prevent further leakage. The study evaluated the technical and clinical success rates of this approach.
Results:
Technical success was achieved in nine of 12 patients (75.0%), with clinical success in eight of these nine patients (88.9%). The mean overall drainage duration after tandem placement was 65.0 days (range, 6–154 days), and the mean hospitalization duration for patients with clinical success was 66.7 days (range, 10–156 days).
Conclusion
Simultaneous tandem drainage is a feasible treatment for intra-abdominal abscesses caused by anastomotic leakage and may be a viable option for patients who are not candidates for surgery.
5.Potential of 6-mm-diameter fully covered self-expandable metal stents for unresectable malignant distal biliary obstruction: a propensity score-matched study
Daiki YAMASHIGE ; Susumu HIJIOKA ; Yoshikuni NAGASHIO ; Yuta MARUKI ; Soma FUKUDA ; Shin YAGI ; Kohei OKAMOTO ; Hidenobu HARA ; Yuya HAGIWARA ; Daiki AGARIE ; Tetsuro TAKASAKI ; Akihiro OHBA ; Shunsuke KONDO ; Chigusa MORIZANE ; Hideki UENO ; Miyuki SONE ; Yutaka SAITO ; Takuji OKUSAKA
Clinical Endoscopy 2025;58(1):121-133
Background/Aims:
To date, only thinner-diameter metal stents have been evaluated for unresectable malignant distal biliary obstruction (UR-MDBO). This study investigated the outcomes and optimal cohorts for a 6-mm-diameter fully covered self-expandable metal stent (FCSEMS) compared with those for a 10-mm-diameter FCSEMS.
Methods:
This single-center retrospective cohort study included patients who underwent initial transpapillary metal stenting for UR-MDBO. Propensity score matching (1:1) analysis was performed.
Results:
Of 133/68 patients who underwent 6-mm/10-mm-diameter FCSEMS deployment, 59 in each group were selected. The median time to recurrent biliary obstruction was not significantly different between the groups (p=0.46). In contrast, use of the 6-mm-diameter FCSEMS resulted in a significantly reduced incidence of stent-related adverse events (AEs) (p=0.016), especially cholecystitis (p=0.032), and patients aged <70 years were particularly affected by this significant reduction. Among the patients in the end-stage cohort who were unable to continue chemotherapy after FCSEMS deployment, the free rate of stent-related events, including recurrent biliary obstruction and stent-related AEs, was significantly higher in the 6-mm group (p=0.027).
Conclusions
For UR-MDBO, a 6-mm-diameter FCSEMS can be an optimal and safe option in the younger cohort with a relatively high risk of AEs and in the end-stage cohort requiring safer drainage without interference from stent-related events during times of poor prognosis.
6.Evaluation of simultaneous tandem drainage of intra-abdominal abscesses caused by gastrointestinal anastomotic failure
Yutaka UENO ; Shuji KARIYA ; Miyuki NAKATANI ; Yasuyuki ONO ; Takuji MARUYAMA ; Yuki TANAKA ; Kanji SUGIURA ; Noboru TANIGAWA
International Journal of Gastrointestinal Intervention 2025;14(2):71-76
Background:
This study aimed to demonstrate the effectiveness of a percutaneous method for treating intra-abdominal abscesses caused by gastrointestinal anastomotic leakage using tandem catheter placement for simultaneous drainage.
Methods:
This retrospective study involved 12 patients with intra-abdominal abscesses from anastomotic leakage who underwent image-guided percutaneous drainage. In the tandem drainage technique, one or more catheters were inserted into the abscess while an additional catheter was advanced into the gastrointestinal tract through the anastomotic dehiscence to decompress the tract and prevent further leakage. The study evaluated the technical and clinical success rates of this approach.
Results:
Technical success was achieved in nine of 12 patients (75.0%), with clinical success in eight of these nine patients (88.9%). The mean overall drainage duration after tandem placement was 65.0 days (range, 6–154 days), and the mean hospitalization duration for patients with clinical success was 66.7 days (range, 10–156 days).
Conclusion
Simultaneous tandem drainage is a feasible treatment for intra-abdominal abscesses caused by anastomotic leakage and may be a viable option for patients who are not candidates for surgery.
7.Efficacy of hemostasis by gastroduodenal covered metal stent placement for hemorrhagic duodenal stenosis due to pancreatobiliary cancer invasion: a retrospective study
Yasunari SAKAMOTO ; Taku SAKAMOTO ; Akihiro OHBA ; Mitsuhito SASAKI ; Shunsuke KONDO ; Chigusa MORIZANE ; Hideki UENO ; Yutaka SAITO ; Yasuaki ARAI ; Takuji OKUSAKA
Clinical Endoscopy 2024;57(5):628-636
Background/Aims:
Advanced pancreatic and biliary tract cancers can invade the duodenum and cause duodenal hemorrhagic stenosis. This study aimed to evaluate the efficacy of covered self-expandable metal stents in the treatment of cancer-related duodenal hemorrhage with stenosis.
Methods:
Between January 2014 and December 2016, metal stents were placed in 51 patients with duodenal stenosis. Among these patients, a self-expandable covered metal stent was endoscopically placed in 10 patients with hemorrhagic duodenal stenosis caused by pancreatobiliary cancer progression. We retrospectively analyzed the therapeutic efficacy of the stents by evaluating the technical and clinical success rates based on successful stent placement, degree of oral intake, hemostasis, stent patency, and overall survival.
Results:
The technical and clinical success rates were 100%. All 10 patients achieved a gastric outlet obstruction scoring system score of three within two weeks after the procedure and had no recurrence of melena. The median stent patency duration and overall survival after stent placement were 52 days (range, 20–220 days) and 66.5 days (range, 31–220 days), respectively.
Conclusions
Endoscopic placement of a covered metal stent for hemorrhagic duodenal stenosis associated with pancreatic or biliary tract cancer resulted in duodenal hemostasis, recanalization, and improved quality of life.
8.A Case of Cardiac Leiomyosarcoma Diagnosed with Recurrence after Resection of the Left Atrial Intramural Hematoma
Kazuya TERAZONO ; Takayuki UENO ; Yoshihiro FUKUMOTO ; Kosuke MUKAIHARA ; Yoshikazu KAWAZU ; Shinya KURAMOTO ; Yuta SHIRAMOMO ; Yutaka IMOTO
Japanese Journal of Cardiovascular Surgery 2018;47(5):224-227
Cardiac leiomyosarcoma and atrial intramural hematoma are extremely rare. Here, we present the case of a 52-year-old woman with dyspnea. Echocardiography showed a large mass in the left atrium. Tumor resection was performed. A pathological diagnosis of intramural hematoma was made. Ten months later, she presented to our hospital again with dyspnea. Echocardiography and computed tomography showed recurrence of the left atrial tumor. Another tumor resection operation was performed. The tumor originated from the inferior wall of the left atrium, and it was surrounded by atrial wall thickening. Complete resection was not possible. Although postoperative chemotherapy was prescribed, the patient died of heart failure nine months after the second operation.
9.Surgical Treatment of Kommerell Diverticulum and the Aberrant Subclavian Artery : Four Case Reports
Hideaki Kanda ; Yukinori Moriyama ; Yutaka Imoto ; Yoshihiro Fukumoto ; Takayuki Ueno ; Kazuya Terazono
Japanese Journal of Cardiovascular Surgery 2017;46(4):173-176
We report 4 cases of aortic graft replacement for Kommerell diverticulum (KD) and the aberrant subclavian artery (ASA). In two patients who had a right-sided aortic arch, KD and the left ASA, we performed descending aorta replacement and in-situ reconstruction of the left ASA via a right lateral thoracotomy. Third patient had a left-sided aortic arch, KD and the right ASA, in whom we performed descending aorta graft replacement via a left lateral thoracotomy with ostial closure of the right ASA. Fourth patient had a left-sided aortic arch, KD and the right ASA, and complicated by acute type A aortic dissection. We performed a total arch repair with frozen elephant trunk procedure via a median sternotomy. All 4 patients survived operations and discharged from the hospital with symptom relief. The choice of approach, a thoracotomy or a median sternotomy, should be based on patient-specific anatomy and extent of graft replacement.
10.Weekly Teriparatide Therapy Rapidly Accelerates Bone Healing in Pyogenic Spondylitis with Severe Osteoporosis.
Akira SHINOHARA ; Yutaka UENO ; Keishi MARUMO
Asian Spine Journal 2014;8(4):498-501
Pyogenic spondylitis is a frequently observed disease in orthopedics, and the number of cases is increasing. Some patients with pyogenic spondylitis suffer from vertebral destruction due to infection. The disease is typically treated with antibiotics, bed rest, spinal support, and lesion curettage; however, vigorous drug therapy against vertebral body destruction by pyogenic spondylitis has not been attempted. In this report, a case of pyogenic spondylitis with spinal destruction caused by infection and treated with once-weekly teriparatide administration is presented. Vertebral body erosion in cortical and cancellous areas by the infection was rapidly repaired after 6 weeks of once-weekly teriparatide treatment. Treatment with once-weekly teriparatide appears to be a new strategy for patients with severe osteoporosis suffering from pyogenic spondylitis.
Anti-Bacterial Agents
;
Bed Rest
;
Bone Density
;
Curettage
;
Drug Therapy
;
Humans
;
Orthopedics
;
Osteoporosis*
;
Quality of Life
;
Spondylitis*
;
Teriparatide*


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