1.Distinctive quality control method for solid-state fermented Isaria cicadae from strain Ic-17-7 and application in a rat model of type 2 diabetes.
Chang-Sheng SUN ; Yu-Qin WANG ; Zhong-Liang ZHANG ; Yuligh LIOU ; Hong-Hao ZHOU
Chinese Journal of Natural Medicines (English Ed.) 2021;19(12):921-929
		                        		
		                        			
		                        			This work was aimed to establish a quality control method for evaluating the effects on glucose and lipids of the fruiting body of Isaria cicadae Miquel from strain Ic-17-7 (Ic-17-7fb) using a rat model of type 2 diabetes (T2DM). Random amplified polymorphic DNA, sequence-characterized amplified region, and high-performance liquid chromatography (HPLC) were used for the quality control of Ic-17-7fb. The pharmacological effects on streptozocin (STZ)-induced high fat diet (HFD)-fed Albino Wistar rats were evaluated. The rats underwent the following treatments: control, metformin, Ic-17-7fb (0.166 and 0.5 g·kg
		                        		
		                        		
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Blood Glucose
		                        			;
		                        		
		                        			Cordyceps
		                        			;
		                        		
		                        			Diabetes Mellitus, Type 2/drug therapy*
		                        			;
		                        		
		                        			Metformin
		                        			;
		                        		
		                        			Quality Control
		                        			;
		                        		
		                        			Rats
		                        			;
		                        		
		                        			Rats, Wistar
		                        			
		                        		
		                        	
            
Result Analysis
Print
Save
E-mail