[Objective]To investigate the efficacy of Liangxue Huoxue Decoction with conventional western medicine in the treatment of blood heat psoriasis complicated with coronary heart disease and the effects on skin barrier function and hemorheology of patients.[Methods]Eighty-eight patients with blood heat psoriasis combined with coronary heart disease from November 2019 to December 2021 were selected and randomly divided into two groups,with 44 patients in each group.The control group was treated with conventional western medicine,and the observation group was treated with Liangxue Huoxue Decoction together with conventional western medicine.The clinical efficacy,adverse reactions,as well as skin barrier function,hemorheological indicators,serum inflammatory factors interleukin-1(IL-1),IL-6,IL-8,and tumor necrosis factor-α(TNF-α),lesion area and severity index(PASI),and Barthel index(BI)were compared before and after treatment between the two groups.[Results]Compared with control group(70.45％),the total effective rate of treatment in observation group(88.64％)was higher(P＜0.05),and there was no statistically significant difference in the incidence of adverse reactions between observation group and control group(P＞0.05).After 2 weeks and 4 weeks of treatment,the stratum corneum water content and sebum content in observation group were higher than control group and the transepidermal water loss,whole blood high cut and low cut viscosity,erythrocyte specific volume,plasma viscosity and IL-1,IL-6,IL-8 and TNF-α level were lower than control group(P＜0.05).After 4 weeks and 12 weeks of treatment,the PASI score was lower and the BI was higher in observation group than control group(P＜0.05).[Conclusion]Liangxue Huoxue Decoction together with conventional western medicine can effectively reduce the inflammatory response of the body and improve the skin barrier function and hemorheological indicators in the treatment of patients with psoriasis combined with coronary heart disease,with good effect and high safety.

ZHANG Jing-yue was a distinguished physician in Chinese medical history,He dared to innovate, and established his achievements in diagnosis and treatment of internal emergency.In clinical internal emergency,such as yang depletion,exuberant yin repelling yang,decline of vital gate-fire,dyspnea due to kidney deficiency,and apoplexy,he suggested that physicians grasp pathogenesis,and apply warming kidney,nourishing kidney,banking up and nourishing spirit.His distinct academic thinking is beneficial to diagnosis and treatment in internal emergency nowadays.

Mr.Cao Bingzhang,a master of TCM,compiled the ‘China Cheng Xue Da Cheng’ and so on.He is well experienced,absorbing the advanced techniques of others.He holds that to make out a prescription according to the syndromes other than the diseases.He argues that prescriptions are maintained,but disease varies. However,we should adopt the prescriptions according to the different syndromes.Thus,when patients are in critical moment or are very ill,syndrome differentiation always brings him through.He gets his own experience in examination of tongue and is good at phlegm syndrome therapy.What’s more, prevention and careful nursing are attached more importance.