Purpose: Obesity refers to a condition in which there is excessive fat in the body and is caused by an imbalanced diet and a decrease in physical activity. Accordingly, regular exercise is reported to help improve and prevent obesity. Therefore, this study investigated the effects of short-term resistance training (RT) on weight loss, lipid profiles, blood pressure, atherogenic indices, and inflammation in middle-aged mice. Methods: Adult mice (7.5-month-old) were randomly divided into three groups comprising 7 mice per group: a normal diet group (NDC); a high-fat diet group (HDC, 45% total calories as fat); and a high-fat diet plus resistance training group (HDRT). The mice in the resistance training group performed climbing exercises using a ladder for the experimental period of 5 days/week for 4 weeks. The indicated intensity load was adjusted by individual % of animal body weight. The load gradually increased every week, and a total of 4 repetitions/set and 3 sets/day with 1 minute of rest provided between sets were performed. After sacrifice, analysis of serum and mRNA expression in the tissues were performed. Results: The HDC group showed a significant increase in systolic blood pressure (SBP) compared to the NDC group, while the HDRT group had a lower SBP relative to the HDC group. RT significantly improved blood lipid levels (triglycerides [TG], low-density lipoprotein [LDL], non-high-density lipoprotein [nonHDL], and very-low-density lipoprotein cholesterol [VLDL-C]). Arteriosclerosis improved through resistance training as observed in the changes in the arteriosclerosis indices (atherogenic index of plasma [AIP], Castelli risk index [CRI]-I, CRI-II, and atherogenic coefficient [AC]). In addition, the HDRT group showed decreased mRNA expression levels of tumor necrosis factor-alpha (Tnfa), interleukin-1 beta (Il-1b), and Il-6 in muscle tissue when compared with the HDC. Conclusion This study confirmed that RT improves blood lipids and inflammation profiles, regulates blood pressure, and improves atherosclerosis in obese mice.

Purpose: Obesity refers to a condition in which there is excessive fat in the body and is caused by an imbalanced diet and a decrease in physical activity. Accordingly, regular exercise is reported to help improve and prevent obesity. Therefore, this study investigated the effects of short-term resistance training (RT) on weight loss, lipid profiles, blood pressure, atherogenic indices, and inflammation in middle-aged mice. Methods: Adult mice (7.5-month-old) were randomly divided into three groups comprising 7 mice per group: a normal diet group (NDC); a high-fat diet group (HDC, 45% total calories as fat); and a high-fat diet plus resistance training group (HDRT). The mice in the resistance training group performed climbing exercises using a ladder for the experimental period of 5 days/week for 4 weeks. The indicated intensity load was adjusted by individual % of animal body weight. The load gradually increased every week, and a total of 4 repetitions/set and 3 sets/day with 1 minute of rest provided between sets were performed. After sacrifice, analysis of serum and mRNA expression in the tissues were performed. Results: The HDC group showed a significant increase in systolic blood pressure (SBP) compared to the NDC group, while the HDRT group had a lower SBP relative to the HDC group. RT significantly improved blood lipid levels (triglycerides [TG], low-density lipoprotein [LDL], non-high-density lipoprotein [nonHDL], and very-low-density lipoprotein cholesterol [VLDL-C]). Arteriosclerosis improved through resistance training as observed in the changes in the arteriosclerosis indices (atherogenic index of plasma [AIP], Castelli risk index [CRI]-I, CRI-II, and atherogenic coefficient [AC]). In addition, the HDRT group showed decreased mRNA expression levels of tumor necrosis factor-alpha (Tnfa), interleukin-1 beta (Il-1b), and Il-6 in muscle tissue when compared with the HDC. Conclusion This study confirmed that RT improves blood lipids and inflammation profiles, regulates blood pressure, and improves atherosclerosis in obese mice.

Purpose: Obesity refers to a condition in which there is excessive fat in the body and is caused by an imbalanced diet and a decrease in physical activity. Accordingly, regular exercise is reported to help improve and prevent obesity. Therefore, this study investigated the effects of short-term resistance training (RT) on weight loss, lipid profiles, blood pressure, atherogenic indices, and inflammation in middle-aged mice. Methods: Adult mice (7.5-month-old) were randomly divided into three groups comprising 7 mice per group: a normal diet group (NDC); a high-fat diet group (HDC, 45% total calories as fat); and a high-fat diet plus resistance training group (HDRT). The mice in the resistance training group performed climbing exercises using a ladder for the experimental period of 5 days/week for 4 weeks. The indicated intensity load was adjusted by individual % of animal body weight. The load gradually increased every week, and a total of 4 repetitions/set and 3 sets/day with 1 minute of rest provided between sets were performed. After sacrifice, analysis of serum and mRNA expression in the tissues were performed. Results: The HDC group showed a significant increase in systolic blood pressure (SBP) compared to the NDC group, while the HDRT group had a lower SBP relative to the HDC group. RT significantly improved blood lipid levels (triglycerides [TG], low-density lipoprotein [LDL], non-high-density lipoprotein [nonHDL], and very-low-density lipoprotein cholesterol [VLDL-C]). Arteriosclerosis improved through resistance training as observed in the changes in the arteriosclerosis indices (atherogenic index of plasma [AIP], Castelli risk index [CRI]-I, CRI-II, and atherogenic coefficient [AC]). In addition, the HDRT group showed decreased mRNA expression levels of tumor necrosis factor-alpha (Tnfa), interleukin-1 beta (Il-1b), and Il-6 in muscle tissue when compared with the HDC. Conclusion This study confirmed that RT improves blood lipids and inflammation profiles, regulates blood pressure, and improves atherosclerosis in obese mice.

Purpose: Bibimbap is a traditional Korean dish that has gained global recognition owing to its unique combination of flavors and nutritional balance. The dish is made by mixing cooked rice with various ingredients, including seasoned vegetables, marinated meat, fermented condiments, and healthy oils. This dish represents Korean culinary culture and offers potential health benefits because of its balanced nutritional composition. The primary objective of this review was to examine the nutritional value, functional properties, and cultural significance of bibimbap. By analyzing bibimbap through traditional and modern scientific perspectives, this study aimed to highlight its role as a nutritious, balanced, and globally recognized dish. Methods: This review used a systematic literature review approach to examine the nutritional value and functionality of bibimbap. Results: Bibimbap is a nutritionally balanced dish that incorporates a variety of food groups.Rice provides complex carbohydrates, offering sustained energy, while vegetables contribute essential vitamins, minerals, and antioxidants. Protein is supplied by meat, and healthy fats come from vegetable oil. Bibimbap also embodies the traditional Korean philosophy of ' Five Elements Theory,' symbolized by the five colors of its ingredients: white, red, blue, yellow, and green. These colors represent balance and harmony and align with modern nutritional science, which emphasizes the health benefits of diverse food components. Although existing studies suggest that bibimbap may have functional properties, such as anti-cancer, antioxidant, and immune-enhancing effects, the current research on its specific health benefits is limited. Conclusion Although bibimbap shows promise in terms of its functional health benefits, further research will be needed to substantiate these claims. This review highlights the potential of bibimbap as a globally recognized healthy dish while preserving its cultural identity. These findings highlight the need for additional research to explore and understand the health-promoting properties of bibimbap.

Purpose: Bibimbap is a traditional Korean dish that has gained global recognition owing to its unique combination of flavors and nutritional balance. The dish is made by mixing cooked rice with various ingredients, including seasoned vegetables, marinated meat, fermented condiments, and healthy oils. This dish represents Korean culinary culture and offers potential health benefits because of its balanced nutritional composition. The primary objective of this review was to examine the nutritional value, functional properties, and cultural significance of bibimbap. By analyzing bibimbap through traditional and modern scientific perspectives, this study aimed to highlight its role as a nutritious, balanced, and globally recognized dish. Methods: This review used a systematic literature review approach to examine the nutritional value and functionality of bibimbap. Results: Bibimbap is a nutritionally balanced dish that incorporates a variety of food groups.Rice provides complex carbohydrates, offering sustained energy, while vegetables contribute essential vitamins, minerals, and antioxidants. Protein is supplied by meat, and healthy fats come from vegetable oil. Bibimbap also embodies the traditional Korean philosophy of ' Five Elements Theory,' symbolized by the five colors of its ingredients: white, red, blue, yellow, and green. These colors represent balance and harmony and align with modern nutritional science, which emphasizes the health benefits of diverse food components. Although existing studies suggest that bibimbap may have functional properties, such as anti-cancer, antioxidant, and immune-enhancing effects, the current research on its specific health benefits is limited. Conclusion Although bibimbap shows promise in terms of its functional health benefits, further research will be needed to substantiate these claims. This review highlights the potential of bibimbap as a globally recognized healthy dish while preserving its cultural identity. These findings highlight the need for additional research to explore and understand the health-promoting properties of bibimbap.

Purpose: Bibimbap is a traditional Korean dish that has gained global recognition owing to its unique combination of flavors and nutritional balance. The dish is made by mixing cooked rice with various ingredients, including seasoned vegetables, marinated meat, fermented condiments, and healthy oils. This dish represents Korean culinary culture and offers potential health benefits because of its balanced nutritional composition. The primary objective of this review was to examine the nutritional value, functional properties, and cultural significance of bibimbap. By analyzing bibimbap through traditional and modern scientific perspectives, this study aimed to highlight its role as a nutritious, balanced, and globally recognized dish. Methods: This review used a systematic literature review approach to examine the nutritional value and functionality of bibimbap. Results: Bibimbap is a nutritionally balanced dish that incorporates a variety of food groups.Rice provides complex carbohydrates, offering sustained energy, while vegetables contribute essential vitamins, minerals, and antioxidants. Protein is supplied by meat, and healthy fats come from vegetable oil. Bibimbap also embodies the traditional Korean philosophy of ' Five Elements Theory,' symbolized by the five colors of its ingredients: white, red, blue, yellow, and green. These colors represent balance and harmony and align with modern nutritional science, which emphasizes the health benefits of diverse food components. Although existing studies suggest that bibimbap may have functional properties, such as anti-cancer, antioxidant, and immune-enhancing effects, the current research on its specific health benefits is limited. Conclusion Although bibimbap shows promise in terms of its functional health benefits, further research will be needed to substantiate these claims. This review highlights the potential of bibimbap as a globally recognized healthy dish while preserving its cultural identity. These findings highlight the need for additional research to explore and understand the health-promoting properties of bibimbap.

Objective: Atrial fibrillation (AF) increases the risk of thromboembolic events, making oral anticoagulants (OACs) essential for high-risk patients. This fact sheet provides nationwide statistics on AF management for stroke prevention in Korea. We aimed to evaluate current anticoagulation treatment trends and strategies in Korea.MethodThe Korean national health claims database from the National Health Insurance Service was used. AF patients aged ≥ 18 years from 2013 to 2022 were included. OAC use, including warfarin and non-vitamin K antagonist OACs (NOACs), was tracked through prescription data. The rates of OAC use were calculated based on continued use, considering prescription dates and amounts. For patients with multiple encounters, the last encounter was used for analysis. Results: During the study, 20.4% of strokes were accompanied by AF, with AF diagnosed within 6 months before or after the stroke. The number of patients diagnosed with AF after a stroke increased from 4893 in 2013 to 6978 in 2022. Among newly diagnosed AF patients requiring OACs, 51% were not prescribed OACs within 6 months. OAC treatment rates for high-risk AF patients increased from 44.6% in 2013 to 77.5% in 2022, with NOAC prescriptions rising significantly after 2015. Regional variations in OAC prescription rates were observed, with lower rates in suburban/rural areas than in urban regions (76.0% vs. 79.6%, p < 0.001). Conclusions Considerable strokes could have been prevented with earlier AF detection and OAC treatment through more intensive electrocardiogram screening.

Background: The benefits of transradial access (TRA) over transfemoral access (TFA) for bifurcation percutaneous coronary intervention (PCI) are uncertain because of the limited availability of device selection. This study aimed to compare the procedural differences and the in-hospital and long-term outcomes of TRA and TFA for bifurcation PCI using secondgeneration drug-eluting stents (DESs). Methods: Based on data from the Coronary Bifurcation Stenting Registry III, a retrospective registry of 2,648 patients undergoing bifurcation PCI with second-generation DES from 21 centers in South Korea, patients were categorized into the TRA group (n = 1,507) or the TFA group (n = 1,141). After propensity score matching (PSM), procedural differences, in-hospital outcomes, and device-oriented composite outcomes (DOCOs; a composite of cardiac death, target vessel-related myocardial infarction, and target lesion revascularization) were compared between the two groups (772 matched patients each group). Results: Despite well-balanced baseline clinical and lesion characteristics after PSM, the use of the two-stent strategy (14.2% vs. 23.7%, P = 0.001) and the incidence of in-hospital adverse outcomes, primarily driven by access site complications (2.2% vs. 4.4%, P = 0.015), were significantly lower in the TRA group than in the TFA group. At the 5-year follow-up, the incidence of DOCOs was similar between the groups (6.3% vs. 7.1%, P = 0.639). Conclusion The findings suggested that TRA may be safer than TFA for bifurcation PCI using second-generation DESs. Despite differences in treatment strategy, TRA was associated with similar long-term clinical outcomes as those of TFA. Therefore, TRA might be the preferred access for bifurcation PCI using second-generation DES.

Background/Aims: Acid-suppressive drugs, such as proton pump inhibitors (PPIs), are treatment options for functional dyspepsia (FD). However, the efficacy of potassium-competitive acid blockers (P-CABs) in treating FD has not yet been established. This prospective multicenter clinical trial-based study aimed to assess the efficacy and safety of tegoprazan as a P-CAB treatment in patients with FD. Methods: FD was diagnosed using the Rome IV criteria. All patients received tegoprazan 50 mg once daily for 8 weeks. Dyspeptic symptoms were assessed using a dyspepsia symptom questionnaire (5-point Likert scale, Nepean Dyspepsia Index-Korean [NDI-K], and gastroesophageal reflux disease–health-related quality of life [GERD-HRQL]). The main outcome was satisfactory symptom relief rates at 8 weeks. Results: In this study, from the initial screening of 209 patients, 173 were included in the per-protocol set analysis. Satisfactory symptom relief rates at 8 and 4 weeks were 86.7% and 74.6%, respectively. In addition, the NDI-K and GERD-HRQL scores significantly improved at 8 and 4 weeks compared with the baseline scores. The efficacy of tegoprazan was not influenced by the FD subtype or Helicobacter pylori status. In patients with overlapping FD and GERD, there was a greater improvement in the NDI-K and GERD-HRQL scores than in patients with FD symptoms only. No serious drug-related adverse events occurred during this study. Conclusion Tegoprazan (50 mg) administered once daily provided satisfactory symptom relief for FD.

BACKGROUND/OBJECTIVES: This study explores the parental characteristics that affect the eating behaviors of preschool children. The nutrition quotient for preschool children (NQ-P) tool was applied to measure the eating behaviors of preschool children, and the relationship between parents’ health beliefs and children’s eating behaviors was investigated by applying the health belief model.MATERIALS/METHODS: In August 2018, a self-administered online survey was conducted on a sample of parents of children aged 3 to 5 years living in the Seoul and Gyeonggi area. A total of 248 respondents were analyzed via descriptive statistics, one-way ANOVA, Tukey’s multiple comparison test, Pearson correlation analysis, and multiple regression analysis. RESULTS: The eating behaviors of preschool children significantly differed based on parents’ education level and monthly income (P < 0.01). Among the factors of the health belief model, “perceived benefit” had the highest score at 4.37 points. The multiple regression analysis confirmed that parents’ “self-efficacy” raised the NQ-P scores (β = 0.175, P< 0.05), balance scores (β = 0.204, P < 0.01), and environment scores of preschool children (β = 0.149,P < 0.05). The study results showed that if parents are educated on healthy eating habits and their level of self-efficacy for healthy eating practices increases, the formation of correct eating behaviors for preschool children is more likely. CONCLUSION This study provides preliminary data to develop an education program for parents to understand proper eating behaviors for their children and may help form healthy eating habits and encourage the healthy growth of preschool children.