1.Long-term clinical outcomes after high and low ligations with lymph node dissection around the root of the inferior mesenteric artery in patients with rectal cancer
Min Wan LEE ; Sung Sil PARK ; Kiho YOU ; Dong Eun LEE ; Dong Woon LEE ; Sung Chan PARK ; Kyung Su HAN ; Dae Kyung SOHN ; Chang Won HONG ; Bun KIM ; Byung Chang KIM ; Hee Jin CHANG ; Dae Yong KIM ; Jae Hwan OH
Annals of Coloproctology 2024;40(1):62-73
Purpose:
This study aimed to evaluate the long-term clinical outcomes based on the ligation level of the inferior mesenteric artery (IMA) in patients with rectal cancer.
Methods:
This was a retrospective analysis of a prospectively collected database that included all patients who underwent elective low anterior resection for rectal cancer between January 2013 and December 2019. The clinical outcomes included oncological outcomes, postoperative complications, and functional outcomes. The oncological outcomes included overall survival (OS) and relapse-free survival (RFS). The functional outcomes, including defecatory and urogenital functions, were analyzed using the Fecal Incontinence Severity Index, International Prostate Symptom Score, and International Index of Erectile Function questionnaires.
Results:
In total, 545 patients were included in the analysis. Of these, 244 patients underwent high ligation (HL), whereas 301 underwent low ligation (LL). The tumor size was larger in the HL group than in the LL group. The number of harvested lymph nodes (LNs) was higher in the HL group than in the LL group. There were no significant differences in complication rates and recurrence patterns between the groups. There were no significant differences in 5-year RFS and OS between the groups. Cox regression analysis revealed that the ligation level (HL vs. LL) was not a significant risk factor for oncological outcomes. Regarding functional outcomes, the LL group showed a significant recovery in defecatory function 1 year postoperatively compared with the HL group.
Conclusion
LL with LNs dissection around the root of the IMA might not affect the oncologic outcomes comparing to HL; however, it has minimal benefit for defecatory function.
2.Treatment for appendicitis in cancer patients on chemotherapy: a retrospective cohort study
Hyung Hwan KIM ; Sung Sil PARK ; Byung Chang KIM ; Kyung Su HAN ; Bun KIM ; Chang Won HONG ; Dae Kyung SOHN ; Kiho YOU ; Dong Woon LEE ; Sung Chan PARK
Annals of Surgical Treatment and Research 2024;107(1):1-7
Purpose:
Whether to perform surgery or conservatively manage appendicitis in immunosuppressed patients is a concern for clinicians. This study aimed to compare the outcomes of these 2 treatment options for appendicitis in patients with cancer undergoing chemotherapy.
Methods:
This retrospective study included 206 patients with cancer who were diagnosed with acute appendicitis between August 2001 and December 2021. Among them, patients who received chemotherapy within 1 month were divided into surgical and conservative groups. We evaluated the outcomes, including treatment success within 1 year, 1-year recurrence, and the number of days from the diagnosis of appendicitis to chemotherapy restart, between the 2 groups.
Results:
Among the 206 patients with cancer who were diagnosed with acute appendicitis, 78 received chemotherapy within 1 month. The patients were divided into surgery (n = 63) and conservative (n = 15) groups. In the surgery group, the duration of antibiotic therapy (7.0 days vs. 16.0 days, P < 0.001) and length of hospital stay (8.0 days vs. 27.5 days, P = 0.002) were significantly shorter than conservative groups. The duration from the diagnosis of appendicitis to the restart of chemotherapy was shorter in the surgery group (20.8 ± 15.1 days vs. 35.2 ± 28.2 days, P = 0.028). The treatment success rate within 1 year was higher in the surgery group (100% vs. 33.3%, P < 0.001).
Conclusion
Surgical treatment showed a significantly higher success rate than conservative treatment for appendicitis in patients less than 1 month after chemotherapy. Further prospective studies will be needed to clinically determine treatment options.
3.Stratification of rate of lymph node metastasis according to risk factors and oncologic outcomes in patients who underwent radical resection for rectal neuroendocrine tumors
Myung Jae JIN ; Sung Sil PARK ; Dong-Eun LEE ; Sung Chan PARK ; Dong Woon LEE ; Kiho YOU ; Hee Jin CHANG ; Chang Won HONG ; Dae Kyung SOHN ; Kyung Su HAN ; Bun KIM ; Byung Chang KIM ; Jae Hwan OH
Annals of Coloproctology 2023;39(6):467-473
Purpose:
Most predictive factors for lymph node metastasis in rectal neuroendocrine tumors (NETs) have been based on local and endoscopic resection. We aimed to evaluate the risk factors for lymph node metastasis in patients who underwent radical resection for rectal NETs and stratify the risk of lymph node metastasis.
Methods:
Sixty-four patients who underwent radical resection for rectal NETs between January 2001 and January 2018 were included. We investigated the risk factors of lymph node metastasis using clinicopathologic data. We also performed a risk stratification for lymph node metastases using the number of previously known risk factors. For oncologic outcomes, the 5-year overall survival and recurrence-free survival were evaluated in both groups.
Results:
Among the patients who underwent radical surgery, 32 (50.0%) had lymph node metastasis and 32 (50.0%) had non–lymph node metastasis. In the multivariable analysis, only the male sex was identified as a risk factor for lymph node metastasis (odds ratio, 3.695; 95% confidence interval, 1.128–12.105; P=0.031). When there were 2 or more known risk factors, the lymph node metastasis rate was significantly higher than when there were one or no risk factors (odds ratio, 3.667; 95% confidence interval, 1.023–13.143; P=0.046). There was also no statistical difference between the 2 groups in 5-year overall survival (P=0.431) and 5-year recurrence-free survival (P=0.144).
Conclusion
We found that the rate of lymph node metastasis increased significantly when the number of known risk factors is 2 or more.
4.Exfoliate cancer cell analysis in rectal cancer surgery: comparison of laparoscopic and transanal total mesorectal excision, a pilot study
Kiho YOU ; Jung-Ah HWANG ; Dae Kyung SOHN ; Dong Woon LEE ; Sung Sil PARK ; Kyung Su HAN ; Chang Won HONG ; Bun KIM ; Byung Chang KIM ; Sung Chan PARK ; Jae Hwan OH
Annals of Coloproctology 2023;39(6):502-512
Purpose:
Minimally invasive surgery (MIS) is currently the standard treatment for rectal cancer. However, its limitations include complications and incomplete total mesorectal resection (TME) due to anatomical features and technical difficulties. Transanal TME (TaTME) has been practiced since 2010 to improve this, but there is a risk of local recurrence and intra-abdominal contamination. We aimed to analyze samples obtained through lavage to compare laparoscopic TME (LapTME) and TaTME.
Methods:
From June 2020 to January 2021, 20 patients with rectal cancer undergoing MIS were consecutively and prospectively recruited. Samples were collected at the start of surgery, immediately after TME, and after irrigation. The samples were analyzed for carcinoembryonic antigen (CEA) and cytokeratin 20 (CK20) through a quantitative real-time polymerase chain reaction. The primary outcome was to compare the detected amounts of CEA and CK20 immediately after TME between the surgical methods.
Results:
Among the 20 patients, 13 underwent LapTME and 7 underwent TaTME. Tumor location was lower in TaTME (7.3 cm vs. 4.6 cm, P=0.012), and negative mesorectal fascia (MRF) was more in LapTME (76.9% vs. 28.6%, P=0.044). CEA and CK20 levels were high in 3 patients (42.9%) only in TaTME. There was 1 case of T4 with incomplete purse-string suture and 1 case of positive MRF with dissection failure. All patients were followed up for an average of 32.5 months without local recurrence.
Conclusion
CEA and CK20 levels were high only in TaTME and were related to tumor factors or intraoperative events. However, whether the detection amount is clinically related to local recurrence remains unclear.
5.Clinical Guidance for Point-of-Care Ultrasound in the Emergency and Critical Care Areas after Implementing Insurance Coverage in Korea
Wook Jin CHOI ; Young Rock HA ; Je Hyeok OH ; Young Soon CHO ; Won Woong LEE ; You Dong SOHN ; Gyu Chong CHO ; Chan Young KOH ; Han Ho DO ; Won Joon JEONG ; Seung Mok RYOO ; Jae Hyun KWON ; Hyung Min KIM ; Su Jin KIM ; Chan Yong PARK ; Jin Hee LEE ; Jae Hoon LEE ; Dong Hyun LEE ; Sin Youl PARK ; Bo Seung KANG
Journal of Korean Medical Science 2020;35(7):54-
Point-of-care ultrasound (POCUS) is a useful tool that is widely used in the emergency and intensive care areas. In Korea, insurance coverage of ultrasound examination has been gradually expanding in accordance with measures to enhance Korean National Insurance Coverage since 2017 to 2021, and which will continue until 2021. Full coverage of health insurance for POCUS in the emergency and critical care areas was implemented in July 2019. The National Health Insurance Act classified POCUS as a single or multiple-targeted ultrasound examination (STU vs. MTU). STU scans are conducted of one organ at a time, while MTU includes scanning of multiple organs simultaneously to determine each clinical situation. POCUS can be performed even if a diagnostic ultrasound examination is conducted, based on the physician's decision. However, the Health Insurance Review and Assessment Service plans to monitor the prescription status of whether the POCUS and diagnostic ultrasound examinations are prescribed simultaneously and repeatedly. Additionally, MTU is allowed only in cases of trauma, cardiac arrest, shock, chest pain, and dyspnea and should be performed by a qualified physician. Although physicians should scan all parts of the chest, heart, and abdomen when they prescribe MTU, they are not required to record all findings in the medical record. Therefore, appropriate prescription, application, and recording of POCUS are needed to enhance the quality of patient care and avoid unnecessary cut of medical budget spending. The present article provides background and clinical guidance for POCUS based on the implementation of full health insurance coverage for POCUS that began in July 2019 in Korea.
Abdomen
;
Budgets
;
Chest Pain
;
Critical Care
;
Dyspnea
;
Emergencies
;
Heart
;
Heart Arrest
;
Insurance Coverage
;
Insurance
;
Insurance, Health
;
Korea
;
Medical Records
;
National Health Programs
;
Patient Care
;
Point-of-Care Systems
;
Prescriptions
;
Shock
;
Thorax
;
Ultrasonography
6.Clinical Guidance for Point-of-Care Ultrasound in the Emergency and Critical Care Areas after Implementing Insurance Coverage in Korea
Wook Jin CHOI ; Young Rock HA ; Je Hyeok OH ; Young Soon CHO ; Won Woong LEE ; You Dong SOHN ; Gyu Chong CHO ; Chan Young KOH ; Han Ho DO ; Won Joon JEONG ; Seung Mok RYOO ; Jae Hyun KWON ; Hyung Min KIM ; Su Jin KIM ; Chan Yong PARK ; Jin Hee LEE ; Jae Hoon LEE ; Dong Hyun LEE ; Sin Youl PARK ; Bo Seung KANG
Journal of Korean Medical Science 2020;35(7):e54-
Point-of-care ultrasound (POCUS) is a useful tool that is widely used in the emergency and intensive care areas. In Korea, insurance coverage of ultrasound examination has been gradually expanding in accordance with measures to enhance Korean National Insurance Coverage since 2017 to 2021, and which will continue until 2021. Full coverage of health insurance for POCUS in the emergency and critical care areas was implemented in July 2019. The National Health Insurance Act classified POCUS as a single or multiple-targeted ultrasound examination (STU vs. MTU). STU scans are conducted of one organ at a time, while MTU includes scanning of multiple organs simultaneously to determine each clinical situation. POCUS can be performed even if a diagnostic ultrasound examination is conducted, based on the physician's decision. However, the Health Insurance Review and Assessment Service plans to monitor the prescription status of whether the POCUS and diagnostic ultrasound examinations are prescribed simultaneously and repeatedly. Additionally, MTU is allowed only in cases of trauma, cardiac arrest, shock, chest pain, and dyspnea and should be performed by a qualified physician. Although physicians should scan all parts of the chest, heart, and abdomen when they prescribe MTU, they are not required to record all findings in the medical record. Therefore, appropriate prescription, application, and recording of POCUS are needed to enhance the quality of patient care and avoid unnecessary cut of medical budget spending. The present article provides background and clinical guidance for POCUS based on the implementation of full health insurance coverage for POCUS that began in July 2019 in Korea.
7.Satisfaction surveys on major subjects in emergency medical system in Korea: joint investigation of the Korean Society of Emergency Medicine and Korean Science Journalists Association.
Dae Hwan KIM ; Kweong Won KANG ; Ho Jung KIM ; You Dong SOHN ; Sang Do SHIN ; Chun Song YOUN ; Dong Hun LEE ; Ji Sook LEE ; Hanjin CHO ; Suk Jae CHOI ; Ki Jeong HONG ; Sungyoup HONG ; Kilwon KIM ; Jinhan LEE ; Taewon MIN
Journal of the Korean Society of Emergency Medicine 2018;29(2):111-126
OBJECTIVE: This study was conducted to investigate satisfaction surveys of the emergency medical system in Korea administered to both members of the Korean Society of Emergency Medicine and patients and their guardians. METHODS: The joint survey was conducted by the Korea Scientist Journalists Association and the Public Affairs Committee of the Korean Society of Emergency Medicine. Questionnaires administered to each group included questions about the general environment, safety, and overcrowding. Satisfaction of medical staffs and awareness of cardiopulmonary resuscitation were only included in the patient questionnaire, while public health was only surveyed in the member questionnaire. The satisfaction was evaluated on a 5-point scale. RESULTS: Patient questionnaires were answered by 20 of 413 national emergency medical centers, and about 4.3% of the medical institutions participated in the questionnaire. A total of 704 reply sheets were returned by patients. Member questionnaires were answered by 280 of the 1,108 members (25%). Among patients, the lowest satisfaction was the item of “medical expenses,” followed by “waiting time”. Among providers, the lowest satisfaction was “appropriateness of medical staff”, while the highest complaint was “overcrowding.” CONCLUSION: Emergency care users had the lowest satisfaction with “medical expenses,” while members had the lowest satisfaction with “lack of manpower” and were most dissatisfied with “violence” and “overcrowding.”
Cardiopulmonary Resuscitation
;
Emergencies*
;
Emergency Medical Services
;
Emergency Medicine*
;
Health Care Surveys
;
Humans
;
Job Satisfaction
;
Joints*
;
Korea*
;
Medical Staff
;
Patient Satisfaction
;
Public Health
8.Analysis the Change of Recognition and Attitude between Before and After Experience of Emergency Medicine Education Program in Medical School Students.
Hyo Jeong CHOI ; Kweong Won KANG ; Young Jun KANG ; Ho Jung KIM ; Jeong Min RYU ; You Dong SOHN ; Sang Do SHIN ; Chun Sung YOUN ; Dong Hun LEE ; Yong Su LIM ; Han Jin CHO ; Suk Jae CHOI ; Ki Jeong HONG
Journal of the Korean Society of Emergency Medicine 2017;28(2):167-175
PURPOSE: This study was performed to analyze the results from a 2016 three-day emergency medicine camp for premedical students. METHODS: The Public Relations Committee of Korea Emergency Medical Association planned the camp. We sent an official letter to 41 universities to recruit participants and create programs for three days. Questionnaires were prepared and analyzed before and after the camp. RESULTS: A total of 37 participants participated. There were three times more males than females. According to the recognition survey, knowledge (3.4±2.0 vs. 7.2±1.8) and preference (5.4±1.8 vs. 7.4±1.4) after the camp were better than before the camp (p<0.05). In detail, anxiety about funerals (3.5±2.5 vs. 2.4±2.8) and perception of the role (5.8±2.2 vs. 4.5±2.6) were improved (p<0.05). Worries regarding physical and psychological burden and danger were also greatly improved (p<0.05). The mean satisfaction was 8.6 points out of 10 points, according to the general survey. CONCLUSION: The three-day camp increased awareness of emergency medicine and improved their preferences.
Anxiety
;
Education*
;
Emergencies*
;
Emergency Medicine*
;
Female
;
Humans
;
Korea
;
Male
;
Public Relations
;
Schools, Medical*
;
Students, Premedical
;
Surveys and Questionnaires
9.Willingness Variability of Bystander Cardiopulmonary Resuscitation in Special Situations.
Hyun Il SEO ; Yong Seok PARK ; Mi Jin LEE ; Jae Yun AHN ; Jong Kun KIM ; Sungbae MOON ; Dong Eun LEE ; You Dong SOHN ; Suk Hee LEE ; Jae Young CHOE
Journal of the Korean Society of Emergency Medicine 2017;28(4):287-293
PURPOSE: This study aims to investigate how variability of bystander cardiopulmonary resuscitation (CPR) willingness may change depending on special situations and to find out factors that enhance CPR willingness in each situation and ways to increase the ratio of bystander CPR. METHODS: A population-based, nationwide study using a structured questionnaire via telephone survey regarding CPR was done in 2015 (n=1,000). A stratified cluster sampling was conducted to assess the impact of age and gender on CPR willingness. The contents of the questionnaire consisted of basic characteristics, CPR training experience, and status. Additionally, respondents were presented with five hypothetical scenarios of cardiopulmonary arrest; family member, stranger, elderly person, preschool child, and pregnant woman. RESULTS: Willingness to perform CPR was low for pregnant women (52.1%) or elders (59.3%), moderate for strangers (73.3%) or children (71.3%), but high for a family members (90.4%). Age, awareness of CPR, training experience of CPR, CPR training by manikin practice, recent CPR training (≤2 years), experience of bystander CPR, family history of severe illness, and awareness of Good Samaritan law all influenced the willingness to perform CPR on bystander in each scenario. CONCLUSION: The willingness of bystander CPR decreased in special situations, especially for elderly and pregnant woman. However, recent CPR training group were more willing in the elderly, and CPR experienced group also showed increased tendency in pregnant woman. It is expected that the rate of bystander CPR can be increased by emphasizing that performing bystander CPR for children, pregnant women, and elders is not different from the general population.
Aged
;
Attitude to Health
;
Cardiopulmonary Resuscitation*
;
Child
;
Child, Preschool
;
Female
;
Heart Arrest
;
Humans
;
Jurisprudence
;
Manikins
;
Pregnant Women
;
Surveys and Questionnaires
;
Telephone
10.A Multicenter Retrospective Case Study of Anaphylaxis Triggers by Age in Korean Children.
So Yeon LEE ; Kangmo AHN ; Jihyun KIM ; Gwang Cheon JANG ; Taek Ki MIN ; Hyeon Jong YANG ; Bok Yang PYUN ; Ji Won KWON ; Myung Hyun SOHN ; Kyung Won KIM ; Kyu Earn KIM ; Jinho YU ; Soo Jong HONG ; Jung Hyun KWON ; Sung Won KIM ; Tae Won SONG ; Woo Kyung KIM ; Hyung Young KIM ; You Hoon JEON ; Yong Ju LEE ; Hae Ran LEE ; Hye Young KIM ; Youngmin AHN ; Hye Yung YUM ; Dong In SUH ; Hyun Hee KIM ; Jin Tack KIM ; Jeong Hee KIM ; Yong Mean PARK ; Sooyoung LEE
Allergy, Asthma & Immunology Research 2016;8(6):535-540
PURPOSE: Although anaphylaxis is recognized as an important, life-threatening condition, data are limited regarding its triggers in different age groups. We aimed to identify anaphylaxis triggers by age in Korean children. METHODS: We performed a retrospective review of medical records for children diagnosed with anaphylaxis between 2009 and 2013 in 23 secondary or tertiary hospitals in South Korea. RESULTS: A total of 991 cases (mean age=5.89±5.24) were reported, with 63.9% involving patients younger than 6 years of age and 66% involving male children. Food was the most common anaphylaxis trigger (74.7%), followed by drugs and radiocontrast media (10.7%), idiopathic factors (9.2%), and exercise (3.6%). The most common food allergen was milk (28.4%), followed by egg white (13.6%), walnut (8.0%), wheat (7.2%), buckwheat (6.5%), and peanut (6.2%). Milk and seafood were the most common anaphylaxis triggers in young and older children, respectively. Drug-triggered anaphylaxis was observed more frequently with increasing age, with antibiotics (34.9%) and nonsteroidal anti-inflammatory drugs (17.9%) being the most common causes. CONCLUSIONS: The most common anaphylaxis trigger in Korean children was food. Data on these triggers show that their relative frequency may vary by age.
Anaphylaxis*
;
Anti-Bacterial Agents
;
Arachis
;
Child*
;
Contrast Media
;
Egg White
;
Epidemiology
;
Fagopyrum
;
Humans
;
Juglans
;
Korea
;
Male
;
Medical Records
;
Milk
;
Retrospective Studies*
;
Seafood
;
Tertiary Care Centers
;
Triticum

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