1.Relationship between peripheral blood neutrophil lymphocyte ratio and osteoporosis in Chinese elderly women
Yanlan QIN ; Lixin XU ; Dong PENG ; Yi WANG ; Chunfen LI ; Yanlin ZHOU ; Tian CHEN ; Peng ZHANG ; Chengjing TANG ; Juan XIA ; Yan LI
Chinese Journal of Primary Medicine and Pharmacy 2020;27(6):708-713
		                        		
		                        			
		                        			Objective:To explore the association of peripheral blood neutrophil lymphocyte ratio(NLR) with primary osteoporosis (POP) in Chinese elderly women.Methods:From December 2015 to April 2019, a total of 788 elderly women in Chongqing Three Gorges Central Hospital were included in this study.They were divided into three groups according to bone mineral density: 242 cases of osteopenia, 206 cases of normal bone mineral density and 340 cases of osteoporosis.Their height, weight, statuses of bone of left femoral neck and results of blood tests were recorded, and the values of BMI, NLR and OSTA were calculated.The SPSS statistics software was used to analyze the differences of parameters among the three groups.Logistic regression analysis was used to get significant independent related factors for osteoporosis.The relationship of NLR and OSTA with T-score of left femoral neck was confirmed by Pearson correlation test.ROC curves were used to define the values of NLR and OSTA in diagnosis of osteoporosis.Results:There were statistically significant differences in age(median values: 66, 68 and 70, χ 2=71.596, P<0.001), BMI(median values: 23.46, 24.04 and 25.415, χ 2=64.936, P<0.001) and NLR(median values: 1.97, 2.435 and 2.84, χ 2=106.218, P<0.001) among the three groups(all P<0.01). Logistic regression analysis demonstrated that age, BMI and NLR were all independent significant related factors.There was correlation of NLR, OSTA with T-score of left femoral neck.In diagnosis of osteoporosis, the cut-off value, maximum Youden index, sensitivity and specificity were 2.395, 0.299, 70.3%, 59.6% for NLR, and -1.315, 0.174, 73.6%, 43.5% for OSTA. Conclusion:NLR has intermediate sensitivity and specificity in screening POP in Chinese elderly women, and deserves future researches.
		                        		
		                        		
		                        		
		                        	
2.Clinical studies on effect of ultrasonically nebulized Houttuynia cordata on respiratory bacteria infection with inflammation
Yanlan MA ; Zhongfu HAN ; Jianrong WANG ; Liming ZHANG ; Lijun QIN ; Yang WANG ; Chengxiu YANG ;
Chinese Traditional and Herbal Drugs 1994;0(04):-
		                        		
		                        			
		                        			Object  To explore the bacteriostatic and anti  inflammation activities of ultrasonically nebulized Houttuynai cordata Thunb   in patients after pneumonectomy   Methods  The patients were randomized into 2 groups   Patients of the experimental group, inhaled ultrasonically nebulized H   cordata, while patients in the control group inhaled ultrasonically nebulized vapors without the addition of H   cordata   Results  Total leucocyte counts on the third and fourth day in the experimental group were significantly lower than that in the control group   Neutrophil ratio in experimental group was also lower in all the 5 days of treatment although nonsignificantly   Meanwhile, occurrence of Gram  negative bacilli colonization in experimental group occurred less than that in the control group   But incidence of fungi colonization appeared higher   Conclusion  Inhalation of ultrasonically nebulized H   cordata can ease the inflammation and inhibit the colonization of Gram  negative bacilli in respiratory tract
		                        		
		                        		
		                        		
		                        	
            
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