Objective To investigate the characteristics of obese children with asthma and to analyze its influencing factors in Yiling area of Yichang. Methods A stratified random cluster sampling method was used to select 379 obese children with asthma in Yiling area from 2018 to 2019, and 210 healthy children in the same period were selected as the control group. The general information of the children was obtained through questionnaire survey. Univariate and multivariate logistic analyses were conducted for statistical analysis of the data. Results The proportion of male, living in city, family history of asthma, second-hand smoke exposure ≥ 5 days / week, vegetable intake and sweet food intake were higher in the obese children with asthma than those in the control group (P < 0.05). Multivariate logistic analysis revealed that male children, living in city, family history of asthma, second-hand smoke exposure, less vegetable intake and more sweet food intake were risk factors for obesity with asthma in children (P < 0.05); ORs (95% CI) were 1.425 (1.057-1.878), 1.347 (1.124-1.742), 2.014 (1.326-4.222), 1.879 (1.879) 415-3.775）, 2.503（1.550-5.730）, 2.184（1.484-5.371）. Conclusion The incidence rate of childhood obesity and asthma in Yiling was higher in male than in female children. Living in city, family history of asthma, secondhand smoke exposure, less vegetable intake and more sweet food intake were the risk factors for obesity and asthma. Development of effective intervention measures is essential to reduce the incidence rate of childhood obesity and asthma in Yiling.