Objective:To explore effects of establishing a modified Subjective Global Assessment (SGA) -based nutritional management scheme in undergoing maintenance hemodialysis (MHD) .Methods:Using the convenient sampling method, a total of 208 patients who received MHD treatment in Jinhua Hospital of Traditional Chinese Medicine from September 2019 to December 2020 were selected as the research subjects. They were divided into the control group and the observation group according to random number table method, with 104 cases in each group. The control group received routine nutrition intervention, while the observation group received nutritional management scheme based on modified SGA at basis of the control group. The nutritional indicators, anthropometric indicators, renal function indicators before and after 6 months of intervention and the total incidence of complications after 6 months of intervention were compared between the two groups.Results:After 6 months of intervention, the nutritional indexes and anthropometric indexes of the observation group were higher than those of the control group and the renal function index were lower than those of the control group, and the differences were statistically significant ( P<0.05) . The total incidence of complications in the observation group was 55.77% (58/104) , which was lower than 80.77% (84/104) in the control group, and the difference was statistically significant ( P<0.05) . Conclusions:The establishment of the modified SGA-based nutritional management scheme in MHD patients can ensure reasonable nutritional intake, improve nutritional index levels, reduce inflammatory response, improve immune function, maintain stable renal function, and reduce the occurrence of complications.