Objective:To investigate the independent influencing factors of body mass index (BMI) growth risk during breast cancer treatment and establish a predictive model, and validate its predictive efficacy.Methods:A retrospective cohort study was conducted by a convenience sampling method. 306 eligible breast cancer patients underwent follow-up at the Tianjin Medical University Cancer Hospital between January and May 2023 were selected as the modeling group. The BMI changes of the modeling group patients were monitored during the study period. Patients with BMI changed < ± 0.5 kg/m 2 were classified as the stable group, while those with BMI changed ≥ 0.5 kg/m 2 were classified as the growth group. Factor analysis was conducted, and a predictive model was established. The fitting effect was verified by the Hosmer-Lemeshow test, and the receiver operating characteristic (ROC) curve was drawn to verify the model′s predictive ability. 110 eligible breast cancer patients underwent follow-up at the Tianjin Medical University Cancer Hospital between June and August 2023 were selected as the validation group to verify the predictive effect of the model. Results:The age of the modeling group patients was (48.89 ± 7.78) years, BMI was (25.53 ± 1.39) kg/m 2 and the age of the validation group patients was (50.18 ± 7.70) years, BMI was(24.31 ± 0.86) kg/m 2, both groups were female, there were no significant differences between the two groups (all P>0.05). Axillary lymph node dissection ( OR=4.196, 95% CI 3.512-9.158), chemotherapy duration ( OR=2.002, 95% CI 1.001-3.003), premenopausal status ( OR=3.257, 95% CI 1.244-3.733), low health behavior capacity ( OR=5.977, 95% CI 2.878-7.893), and low physical activity ( OR=3.755, 95% CI 1.244-11.733) were identified as independent influencing factors of BMI change during breast cancer treatment (all P<0.05). The predictive model was P=0.915, with the ROC curve area of 0.950, a J-index of 0.785, a sensitivity of 0.971, and a specificity of 0.814. Internal and external validation of the model in the validation group revealed a sensitivity of 0.858, a specificity of 0.887, and an accuracy of 97.3%. Conclusion:The predictive model exhibited excellent performance and can serve as a valuable tool for formulating nursing intervention strategies to maintain the BMI stability of breast cancer patients during treatment.

Objective To explore the mediating effect of facial emotion recognition on prosocial behavior of medical students in mask-obscured scenes.Methods Fifty-three medical students from a medical university in Chongqing were enrolled from July to September 2023 to complete the facial emotion recognition task,the dictator gaming task and the state empathy test.Spearman correlation analysis was used to examine the correlation between mask wearing and state empathy,trait empathy and prosocial behaviours,and the PROCESS procedure was used to test the mediation of state empathy and the moderating effect of mask wearing or not.Results ①mask wearing,state empathy and prosocial behaviour were significantly correlated(P＜0.01);② State empathy exerted mediated effect between facial emotion recognition and prosocial behavior,with the largest effect size(47％)for the relative mediating effect of sadness;③The interaction terms of facial emotion recognition and mask wearing had a significant effect on state empathy(P＜0.05).Conclusion Facial emotion recognition can influence prosocial behavior directly and also exert indirect effect on prosocial behavior through state empathy.Compared to the condition without mask wearing,mask wearing can significantly facilitate the effect of happy,sad and neutral emotions on state empathy.

Objective:To investigate the independent influencing factors of wound drainage tube time delay in patients with breast cancer and establish a predictive model.Methods:Patients admitted to Tianjin Medical University Cancer Hospital from January to November 2021 were selected as the research objects. They were divided into sword modeling group (156 cases) and verification group (86 cases) according to the admission time. Delayed time to postoperative wound drainage and extubation in breast cancer patients was the end point, 95 cases of 156 patients in the modeling group whose extubation time was less than or equal to 7 days were set as the normal group, 61 cases whose extubation time were more than 7 days were set as delayed group, and the influencing factors of the two groups were compared to establish the prediction model, Hosmer-Lemeshow test was conduct to verify the fitting effect, used the ROC curve to verify the prediction model performance.Results:Univariate and multivariate Cox proportional hazards regression analysis showed that patients' high BMI, related basic disease history, operation mode, axillary lymph node dissection, breast tumor size (T3, T4) and drainage fluid volume 48 hours (≥50 ml) after operation were independent influencing factors for wound drainage tube time delay ( P<0.05). The prediction model was P=0.822, and the area under the ROC curve was 0.877, and the Youden index was 0.605, the sensitivity was 0.736, and the specificity was 0.869. The research data of 86 cases in the validation group were used as the test set for internal and external validation of the model, and the model verification was 96.51%. Conclusion:This prediction model has a good effect, providing a reference basis for clinical medical workers.

Objective:To systematically integrate domestic and foreign studies on weight management of breast cancer patients, in order to comprehensively understand the experience and influencing factors of breast cancer patients in the process of weight management.Methods:PubMed, Scopus, Embase, Web of Science, CINAHL, PsycINFO, China Biology Medicine disc, CNKI, VIP and Wanfang databases were systematically searched for qualitative research on the experience of breast cancer patients during weight management. The search period was from establishment of the databases to May 2022. The quality of the final included literature was evaluated, and Meta-integration was carried out using the aggregated Meta-integration method of Joanna Briggs Institute Centre for Evidence-based Health Care, Australia.Results:Finally, 13 literatures were included, 46 complete and clear research results were extracted, which were summarized into 11 new categories, and three integrated results were constructed, including multiple effects of weight on psychology after cancer, insufficient weight management effectiveness and negative effects of external factors.Conclusions:Weight gain has a negative effect on the physical and mental health of breast cancer patients. Medical staff should pay more attention to the weight management of breast cancer patients and develop personalized interventions.

Objective:To explore the application effect of pathway nursing combined with multimodal exercise intervention in patients with tumor-associated sarcopenia under multi-disciplinary team.Methods:Using the convenient sampling method, a total of 120 patients with tumor-associated sarcopenia who visited Cancer Center of Henan Provincial People 's Hospital from January 2020 to December 2021 were selected as the research objects. They were divided into the observation group ( n=60) and the control group ( n=60) according to the random number table method. The control group received routine nursing care, while the observation group received multi-disciplinary team pathway nursing combined with multimodal exercise. Skeletal Muscle Mass Index (SMI) , Hand Grip Strength (HGS) , daily walking speed, Cancer Fatigue Scale (CFS) and Irritability, Depression and Anxiety Scale (IDA) scores were compared and analyzed between the two groups. Results:After 4 weeks of intervention, HGS and daily walking speed in the observation group were higher than those in the control group, and the differences were statistically significant ( P<0.05) . After 4 weeks of intervention, the total score of CFS in the observation group was lower than that in the control group, and the scores of physical fatigue, emotional fatigue and cognitive fatigue in the observation group were lower than those in the control group, and the differences were statistically significant ( P<0.05) . After 4 weeks of intervention, the total IDA score of the observation group was lower than that of the control group, and the scores of anxiety, depression, extroversion and introversion stimulation were lower than those of the control group, and the differences were statistically significant ( P<0.05) . Conclusions:Multi-disciplinary team pathway care combined with multimodal exercise can improve the physical fitness of patients with tumor-associated sarcopenia, increase the level of physical activity, relieve fatigue and reduce negative emotions such as anxiety, depression and irritation.

Objective:To explore the main influencing factors of the impact of new nurses′ career transition shock in three years, and to provide theoretical basis for the clinical development of new nurses' vocational training and management strategy.Methods:By using the method of objective sampling, 386 new nurses in 5 first-class tertiary hospitals in Tianjin were selected as the research objects within three years. The Jefferson Scale of Empathy (JSE), Organizational Support Scale (OSS), the Transition Shock of Newly Graduated Nurses Scale (TSNGNS) and the self-designed general information questionnaire were used to analyse the main impact of new nurses' career transition shock in three years.Results:The total score was (85.76±25.14) points for 386 new nurses in three years; the scores of empathy ability and organizational support were (81.24±05.21) points and (45.74±12.51) points. The regression analysis showed that whether a new nurse loves her major, how long she has been engaged in nursing work, empathy, total score of empathy ability and emotional support are the main influencing factors for the impact of the new nurse ′s career transition shock in three years ( t values were 2.068, 2.324, 4.155, 2.137, 3.938, P<0.05). Conclusions:To strengthen the training and emotional support intervention for new nurses who have just been engaged in nursing work for 7-9 months, who have conflicts in nursing work and lack of empathy ability, so as to reduce the impact of their career transition shock.

Objective: To explore the main influencing factors of health tenacity of unmarried female breast cancer patients after operation, and to provide theoretical basis for clinical nursing intervention. Methods: A total of 222 unmarried female breast cancer patients were selected from 3 Grade 3A hospitals in Tianjin (Tianjin Cancer Hospital, Tianjin Central obstetrics and Gynecology Hospital, Tianjin People′s Hospital). The Simplified Coping Style Questionnaire (SCSQ), Social Support Rating Scale (SSRS), was used in the study. The Revised Health Hardiness Inventor (RHHl-24) and the self-designed general data questionnaire were used to analyze the main influence of the patient′s health tenacity. Results: The total score of health tenacity among 222 unmarried female breast cancer patients after operation was 75.58 ± 8.87, which was located at the middle level; the score of positive coping was 2.16 ± 0.53 and negative coping was 1.56 ± 0.44; the total score of social support was 39.93 ± 8.45, which was higher than score of domestic norm. The regression analysis showed that the main factors of health tenacity were social support, the stages of breast cancer, the source of medical expenses, positive coping and place of residence in unmarried female breast cancer patients after operation (t=-5.403-5.908, P<0.05 or 0.01). Conclusions We should strengthen nursing intervention for unmarried female breast cancer patients with low social support, late course of disease, poor economic status, negative coping and non-urban residence, and encourage patients to adopt positive coping style. Provide all-round social support to patients in order to improve the patient's health and tenacity.

Objective : To understand the current situation and characteristics of narcotic drugs and psychotropic drugs abuse or dependence among hospital patients and to provide reference for strengthening the management of narcotic drugs and psychotropic drugs. Methods : We collected clinical data from hospitals in Shandong and Guizhou provinces in 2016 and selected patients with history of narcotic drugs and psychotropic drugs. We investigated them through telephone or face-to-face interview,then described the characteristics of demographic information and abuse or dependence of narcotic drugs and psychotropic drugs in diagnosed drug abusers. Results : A total of 280 patients with drug abuse or dependence were recruited,of which 223 cases from nine hospitals in Shandong and 57 cases from five hospitals in Guizhou. There were 170 male patients,accounting for 60.71%; 193 patients aged 45 years and above,accounting for 68.93%; 223 married patients,accounting for 80.51%; 166 patients with a education level of junior high school and below,accounting for 61.25%; 125 patients engaged in agriculture,accounting for 48.64%. Benzodiazepine was the main drugs abused or dependenced by hospital patients,accounting for 73.57%（206 cases）. There were also 83 cases of polydrug abuse,accounting for 29.64%. Among the patients with drug abuse or dependence,45.71% had no special feelings,41.07% had symptoms or felt uncomfortable after withdrawal; 64.64% was for improving their sleep quality. Conclusion Most patients with abuse or dependence of narcotic drugs and psychotropic drugs are middle- or senior-aged and have polydrug abuse. Benzodiazepine are the main abused drugs. The common reason for narcotic and psychotropic drug abuse or dependence is to have a good sleep.

The caring burden of the relative caregivers of breast cancer covers many aspects which include physiology,psychology,social interaction and economy,and is a multidimensional and complex self-cognitive feeling,involving caregivers themselves,patient and family.In the process of care,there are a large number of physical and mental problems and nursing needs,and the burden of care is affected by a variety of mixed factors.However,effective nursing intervention can reduce the burden of care and negative emotions,improve their quality of life and physical and mental health.

Objective To investigate the relationship between disrupted corticospinal tract (CST) and motor recovery after stroke by using diffusion tensor tracking (DTT). Methods From March, 2012 to June, 2013, 15 chronic stroke patients with left subcortical lesions and 15 age- and sex- matched healthy subjects were performed diffusion tensor imaging (DTI) examination. The CST was tracked by DTT technique, and the damaged values of the CST caused by the stroke lesions were quantified using a CST template generated from healthy controls. Furthermore, the correlations of the damaged values of the CST with Fugl-Meyer Assessment (FMA) were performed. Results The range of the damaged values of CST in stroke patients was 0.00% to 29.6%. There were very strong negative correlation between the damaged values of the CST and FMA scores (the wrist, r = -0.660; hand, r = -0.813; wrist plus hand, r = -0.795, respectively, P < 0.01). It also showed strong negative correlation between the damaged values of the CST and FMA scores (upper limb, r = -0.614; upper limb plus lower limb, r = -0.563, respectively, P < 0.05). Whereas, there was no correlation between the damaged values of the CST and FMA scores of lower limb (r = -0.270, P = 0.331). In addition, the lesion volumes of stroke and FMA scores were not significantly correlated (P > 0.05). Conclusion The severity of motor deficit after stroke was closely related to the overlap of lesions with CST. The damaged values of the CST based on DTT may be used as a potential biomarker to assess motor impairments of upper limbs, especially hand and wrist in stroke patients.