1.Research progress of occupational hazards in plywood manufacturing.
Xiang HUANG ; Yue Ming JIANG ; Qing Qing NONG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2023;41(4):317-320
		                        		
		                        			
		                        			Occupational disease hazards in plywood manufacturing mainly include wood dust, formaldehyde, phenol, ammonia, noise, terpene, microorganisms, etc. The exposure is complex with multiple factors accompanied or coexisted. In the production process, these factors are exceeded, and mass occupational disease hazard events occurred among workers. Exposure to wood dust, formaldehyde, terpene, etc., put workers at increased risk of cancer. This article provides a review of this issue in order to provide a scientific basis for the prevention and control of occupational disease hazards in plywood manufacturing.
		                        		
		                        		
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Wood/chemistry*
		                        			;
		                        		
		                        			Occupational Diseases/chemically induced*
		                        			;
		                        		
		                        			Formaldehyde/adverse effects*
		                        			;
		                        		
		                        			Terpenes
		                        			;
		                        		
		                        			Dust
		                        			;
		                        		
		                        			Occupational Exposure/adverse effects*
		                        			
		                        		
		                        	
2.Analysis of dust monitoring results of dust exposure enterprises in Shenxian from 2017 to 2020.
Guang Qing FU ; Huan Ling YUAN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2023;41(2):123-125
		                        		
		                        			
		                        			Objective: In order to understand the dust concentration in the workplace of dust exposure enterprises in Shenxian. To evaluate the degree of occupational hazard factors of dust exposure enterprises. And provide basis for the formulation of occupational protection standards and management system of dust exposure enterprises. Methods: In February 2022, the dust concentration monitoring data of 89 dust exposure enterprises from 2017 to 2020 by the Shenxian Center for Disease Control and Prevention were collected, and the qualified rates of dust concentration detection of dust exposure enterprises in different years, dust types and enterprise sizes were analyzed. Results: A total of 89 dust enterprises were monitored from 2017 to 2020, 2132 dust samples were collected, and 1818 qualified samples were taken, with a total qualified rate of 85.3%. From 2017 to 2020, the dust detection qualified rates showed a year-by-year increase trend, 78.7% (447/568), 84.1% (471/560), 88.6% (418/472) and 90.6% (482/532), respectively, with statistically significant differences (χ(2)=36.27, P=0.003). The differences in the qualified rates of dust detection samples of silicon dust (66.1%, 41/62), grain dust (86.7%, 1549/1786), cotton dust (84.1%, 106/126) and wood dust (77.2%, 122/158) were statistically significant (χ(2)=29.66, P=0.002). The qualified rate of dust samples in large and medium-sized enterprises (95.1%, 1194/1256) was higher than that of small-sized enterprises (71.2%, 624/876), and the difference was statistically significant (χ(2)=1584.40, P=0.001) . Conclusion: The qualified rate of dust concentration monitoring results of dust exposure enterprises in Shenxian showed an increase trend year by year, while the pualified rate of dust concentration monitoring in small-sized enterprises was low, and the occupational hazard of silica dust was still severe.
		                        		
		                        		
		                        		
		                        			Dust
		                        			;
		                        		
		                        			Silicon
		                        			;
		                        		
		                        			Wood
		                        			;
		                        		
		                        			Workplace
		                        			
		                        		
		                        	
4.Progress in improving the properties of dissolving pulp by enzymes.
Xutao ZHANG ; Lefan MA ; Kunpeng ZHOU ; Hongbing LI ; Faxing QIN ; Wufei XIE ; Yingsheng XU
Chinese Journal of Biotechnology 2020;36(11):2260-2276
		                        		
		                        			
		                        			Dissolving pulp consists of high purity cellulose and is widely used to as raw materials for the production of regenerated cellulose fiber, cellulose ester and cellulose ether. The characteristic of dissolving pulp affects greatly the production and processing performance of subsequent products. The α-cellulose content, hemicellulose content, pulp viscosity, ash, transition metal ion content, fiber morphology, molecular weight distribution of cellulose and the reactivity are the important properties. Because of its green, mild and high efficiency, the application of enzymes in improving the properties of dissolving pulp has a promising application prospect and has been researched significantly. In this review, the main properties of dissolving pulp are presented first, followed by a recommendation of the enzymes to improve these properties. The application and current research of cellulase and xylanase in improving the properties of dissolving pulp are emphasized. The main problems and the future research areas in improving the properties of dissolving pulp by enzymes are revealed. Finally, the technology prospects in this field are proposed.
		                        		
		                        		
		                        		
		                        			Cellulase
		                        			;
		                        		
		                        			Molecular Weight
		                        			;
		                        		
		                        			Viscosity
		                        			;
		                        		
		                        			Wood
		                        			
		                        		
		                        	
5.Study on sesquiterpenes from agarwood originating from Gyrinops salicifolia.
Hui-Qin CHEN ; Feng-Juan GUO ; Cai-Hong CAI ; Wen-Hua DONG ; Hao WANG ; Wei LI ; Wen-Li MEI ; Hao-Fu DAI
China Journal of Chinese Materia Medica 2019;44(11):2274-2277
		                        		
		                        			
		                        			Two sesquiterpenes were isolated from the agarwood originating from Gyrinops salicifolia with various chromatographic techniques, and their structures were determined as 12-hydroxy-dihydrocyperolone(1) and(rel)-4β,5β,7β-eremophil-9-en-12,8α-olide(2), through a combined analysis of physicochemical properties and spectroscopic evidence. Compound 1 was a new compound. Compound 2 showed cytotoxicities against K562 and BEL-7401 cell lines, with IC_(50) values of(17.85±0.04) and(21.82±0.07) mg·L~(-1), respectively [taxol as positive control, with IC_(50) values of(1.97±0.11) and(6.31±0.08) mg·L~(-1)].
		                        		
		                        		
		                        		
		                        			Antineoplastic Agents, Phytogenic
		                        			;
		                        		
		                        			isolation & purification
		                        			;
		                        		
		                        			pharmacology
		                        			;
		                        		
		                        			Cell Line, Tumor
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Molecular Structure
		                        			;
		                        		
		                        			Phytochemicals
		                        			;
		                        		
		                        			isolation & purification
		                        			;
		                        		
		                        			pharmacology
		                        			;
		                        		
		                        			Sesquiterpenes
		                        			;
		                        		
		                        			isolation & purification
		                        			;
		                        		
		                        			pharmacology
		                        			;
		                        		
		                        			Thymelaeaceae
		                        			;
		                        		
		                        			chemistry
		                        			;
		                        		
		                        			Wood
		                        			;
		                        		
		                        			chemistry
		                        			
		                        		
		                        	
6.Workplace Diesel Exhausts and Gasoline Exposure and Risk of Colorectal Cancer in Four Nordic Countries
Madar TALIBOV ; Jorma SORMUNEN ; Elisabete WEIDERPASS ; Kristina KJAERHEIM ; Jan Ivar MARTINSEN ; Per SPAREN ; Laufey TRYGGVADOTTIR ; Johnni HANSEN ; Eero PUKKALA
Safety and Health at Work 2019;10(2):141-150
		                        		
		                        			
		                        			BACKGROUND: Evidence on associations between occupational diesel exhaust and gasoline exposure and colorectal cancer is limited. We aimed to assess the effect of workplace exposure to diesel exhaust and gasoline on the risk of colorectal cancer. METHODS: This caseecontrol study included 181,709 colon cancer and 109,227 rectal cancer cases diagnosed between 1961 and 2005 in Finland, Iceland, Norway, and Sweden. Cases and controls were identified from the Nordic Occupational Cancer Study cohort and matched for country, birth year, and sex. Diesel exhaust and gasoline exposure values were assigned by country-specific job-exposure matrices. Odds ratios and 95% confidence intervals were calculated by using conditional logistic regression models. The results were adjusted for physical strain at work and occupational exposure to benzene, formaldehyde, ionizing radiation, chlorinated hydrocarbons, chromium, and wood dust. RESULTS: Diesel exhaust exposure was associated with a small increase in the risk of rectal cancer (odds ratio 1/4 1.05, 95% confidence interval 1.02–1.08). Gasoline exposure was not associated with colorectal cancer risk. CONCLUSION: This study showed a small risk increase for rectal cancer after workplace diesel exhaust exposure. However, this finding could be due to chance, given the limitations of the study.
		                        		
		                        		
		                        		
		                        			Benzene
		                        			;
		                        		
		                        			Case-Control Studies
		                        			;
		                        		
		                        			Chromium
		                        			;
		                        		
		                        			Cohort Studies
		                        			;
		                        		
		                        			Colonic Neoplasms
		                        			;
		                        		
		                        			Colorectal Neoplasms
		                        			;
		                        		
		                        			Dust
		                        			;
		                        		
		                        			Finland
		                        			;
		                        		
		                        			Formaldehyde
		                        			;
		                        		
		                        			Gasoline
		                        			;
		                        		
		                        			Hydrocarbons, Chlorinated
		                        			;
		                        		
		                        			Iceland
		                        			;
		                        		
		                        			Logistic Models
		                        			;
		                        		
		                        			Norway
		                        			;
		                        		
		                        			Occupational Exposure
		                        			;
		                        		
		                        			Odds Ratio
		                        			;
		                        		
		                        			Parturition
		                        			;
		                        		
		                        			Radiation, Ionizing
		                        			;
		                        		
		                        			Rectal Neoplasms
		                        			;
		                        		
		                        			Scandinavian and Nordic Countries
		                        			;
		                        		
		                        			Sweden
		                        			;
		                        		
		                        			Vehicle Emissions
		                        			;
		                        		
		                        			Wood
		                        			
		                        		
		                        	
7.Second hand smoke exposure in workplace by job status and occupations
Hyunhee PARK ; Sung il CHO ; Changhun LEE
Annals of Occupational and Environmental Medicine 2019;31(1):3-
		                        		
		                        			
		                        			BACKGROUND: The objective of this study is to evaluate the risk of exposure to second hand smoke (SHS) during working hours by job status and occupation. METHODS: Using the 4th Korean Working Conditions Survey (KWCS), 49,674 respondents who answered the question about SHS were studied. A chi-square test was carried out to determine whether there is a significant different in SHS exposure frequency by general and occupational characteristics and experience of discrimination at work and logistic regression analysis was carried out to identify the risk level of SHS exposure by variables. RESULTS: In this study, we found that male workers in their 40s and 50s, workers employed in workplaces with fewer than 50 employees, daily workers, and people working outdoors had a higher rate of exposure to SHS than the others. The top five occupations with the highest SHS exposure were construction and mining-related occupations, metal core-makers-related trade occupations, wood and furniture, musical instrument, and signboard-related trade occupations, transport and machine-related trade occupations, transport and leisure services occupations. The least five exposed occupations were public and enterprise senior officers, legal and administrative professions, education professionals, and health, social welfare, and religion-related occupations. CONCLUSION: Tobacco smoke is a significant occupational hazard. Smoking ban policy in the workplace can be a very effective way to reduce the SHS exposure rate in the workplace and can be more effective if specifically designed by the job status and various occupations.
		                        		
		                        		
		                        		
		                        			Discrimination (Psychology)
		                        			;
		                        		
		                        			Education
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Interior Design and Furnishings
		                        			;
		                        		
		                        			Leisure Activities
		                        			;
		                        		
		                        			Logistic Models
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Music
		                        			;
		                        		
		                        			Occupations
		                        			;
		                        		
		                        			Smoke
		                        			;
		                        		
		                        			Smoking
		                        			;
		                        		
		                        			Social Welfare
		                        			;
		                        		
		                        			Surveys and Questionnaires
		                        			;
		                        		
		                        			Tobacco
		                        			;
		                        		
		                        			Tobacco Smoke Pollution
		                        			;
		                        		
		                        			Wood
		                        			
		                        		
		                        	
8.Discussion on medicinal value of Saposhnikoviae Radix based on difference of ketone content in cortex and wood of Saposhnikoviae Radix.
Dan ZHANG ; Pan-Pan MU ; Mei GUO ; Ji-Wei WANG ; Kai-Yan ZHENG ; Fang-Jie HOU ; Long GUO ; Yu-Guang ZHENG
China Journal of Chinese Materia Medica 2019;44(18):3948-3953
		                        		
		                        			
		                        			In order to confirm the tradition that bolting Saposhnikoviae Radix could not be used as medicine,the content of four chromone components in the cortex and wood of Saposhnikoviae Radix was analyzed by high performance liquid chromatography( HPLC),and the chemical fingerprints were established,12 common peaks were calibrated. The similarity analysis found that the similarity between batches was 0. 115-0. 995,it indicates that the cortex and wood of Saposhnikoviae Radix have certain differences. On this basis,systematic clustering analysis,principal component analysis and orthogonal partial least squares discriminant analysis were carried out with the content of four chromone components and whether they met the pharmacopoeia criteria as the original variables. The results showed that the content of the four components in the cortex of Saposhnikoviae Radix was much higher than that in the wood,and the four components detected were able to distinguish the cortex and the wood of Saposhnikoviae Radix. The results of the study reveal the tradition that bolting Saposhnikoviae Radix should not be used as medicine dut to decreased quality.
		                        		
		                        		
		                        		
		                        			Apiaceae/chemistry*
		                        			;
		                        		
		                        			Chromatography, High Pressure Liquid
		                        			;
		                        		
		                        			Drugs, Chinese Herbal/chemistry*
		                        			;
		                        		
		                        			Ketones/analysis*
		                        			;
		                        		
		                        			Plant Roots/chemistry*
		                        			;
		                        		
		                        			Wood/chemistry*
		                        			
		                        		
		                        	
9.Composition analysis,antioxidative and antibacterial activities comparison of agarwood oils extracted by supercritical and steam distillation.
Cheng-Piao TIAN ; Ya-Ling SONG ; Hai-Tang XU ; Si-Qi NIU ; Zhi-Hong WU ; Li-Qun SHEN
China Journal of Chinese Materia Medica 2019;44(18):4000-4008
		                        		
		                        			
		                        			Agarwood is a traditional and precious medicinal material and natural spice in China and other southeast Asian countries.As the head of all spices,agarwood has many pharmacological activities such as analgesia,antidiarrheal,anti-inflammatory and antibacterial effects. Due to its high price and scarce resources,there were just a few previous studies on it,mainly focusing on the chemical compositions of the agarwood essential oil and solvent extract mixture. The components of agarwood oils obtained by supercritical extraction and steam distillation were analyzed by using Gas Chromatography-Mass Spectrometer( GC-MS),and then the agarwood oils compositions and contents were compared between the traditional extraction method and the recently emerging supercritical extraction method. Antioxidant experiments of scavenging DPPH,ABTS,hydroxyl radical,total reducing power and MIC experiments of five kinds of tester strains such as staphylococcus aureus were combined to illustrate the differences between these two kinds of agarwood oils in terms of antioxidant and bacteriostatic activities. The results showed that the main components of agarwood oil were sesquiterpenoids( 68. 68%) in steam distillation extraction method,but sesquiterpenoids( 23. 78%) and chromones( 29. 42%) in supercritical extraction method. Fourteen common components included benzyl acetone,α-santalol,γ-eudesmol,agarospirol and guaiol etc. The antioxidant activity and inhibitory MIC of agarwood oils in supercritical extraction method were better than those in steam distillation method,and the inhibitory effect of agarwood oil on the growth of bacillus subtilis was found for the first time.
		                        		
		                        		
		                        		
		                        			Anti-Bacterial Agents/pharmacology*
		                        			;
		                        		
		                        			Antioxidants/pharmacology*
		                        			;
		                        		
		                        			China
		                        			;
		                        		
		                        			Distillation/methods*
		                        			;
		                        		
		                        			Oils, Volatile/pharmacology*
		                        			;
		                        		
		                        			Plant Oils/pharmacology*
		                        			;
		                        		
		                        			Steam
		                        			;
		                        		
		                        			Thymelaeaceae/chemistry*
		                        			;
		                        		
		                        			Wood/chemistry*
		                        			
		                        		
		                        	
10.Functional disorders of the lung and symptoms of respiratory disease associated with occupational inhalation exposure to wood dust in Iran.
Masoud NEGHAB ; Zeinab JABARI ; Fatemeh KARGAR SHOUROKI
Epidemiology and Health 2018;40(1):e2018031-
		                        		
		                        			
		                        			OBJECTIVES: The possible adverse respiratory effects of airborne pollutants in sawmills have not been thoroughly investigated in Iran. Additionally, the extent to which workers are exposed to this organic dust and its associated bioaerosols has not been extensively quantified. Likewise, the predominant bacterial and fungal species associated with wood dust have not been characterized. The present study was undertaken to address these issues. METHODS: One hundred male individuals exposed to wood dust and 100 unexposed male subjects were investigated. They completed a standardized respiratory symptom questionnaire and underwent spirometry testing. Additionally, airborne concentrations of respirable and inhalable dust particles, bacteria, and fungi were measured. RESULTS: The mean concentrations of inhalable and respirable dust particles, bacteria, and fungi were found to be 2.44, 6.76 mg/m3, 756.38, and 299.15 colony-forming units/m3, respectively. The predominant Gram-negative bacteria in the sawmills included the Pseudomonadaceae, Klebsiella pneumoniae, and Rhinoscleromatis spp., and the predominant fungi consisted of the zygomycetes and Aspergillus spp. Respiratory symptoms were significantly more prevalent among exposed workers. Significant cross-shift decrements were noted in some pulmonary function parameters. Similarly, pre-shift spirometry results indicated that some pulmonary function parameters were significantly lower in the exposed group. CONCLUSIONS: Exposure to wood dust and its bioaerosols was associated with significantly higher prevalence of respiratory symptoms and both acute (i.e., partially reversible) and chronic (i.e., irreversible) decrements in the functional capacity of the lung. Additionally, the characterized bioaerosols did not differ significantly from those isolated in other parts of the world.
		                        		
		                        		
		                        		
		                        			Aspergillus
		                        			;
		                        		
		                        			Bacteria
		                        			;
		                        		
		                        			Dust*
		                        			;
		                        		
		                        			Fungi
		                        			;
		                        		
		                        			Gram-Negative Bacteria
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Inhalation Exposure*
		                        			;
		                        		
		                        			Inhalation*
		                        			;
		                        		
		                        			Iran*
		                        			;
		                        		
		                        			Klebsiella pneumoniae
		                        			;
		                        		
		                        			Lung*
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Prevalence
		                        			;
		                        		
		                        			Pseudomonadaceae
		                        			;
		                        		
		                        			Respiratory Function Tests
		                        			;
		                        		
		                        			Spirometry
		                        			;
		                        		
		                        			Wood*
		                        			
		                        		
		                        	
            
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