2.Magnetic resonance imaging of diabetic foot complications.
Keynes T A LOW ; Wilfred C G PEH
Singapore medical journal 2015;56(1):23-quiz 34
		                        		
		                        			
		                        			This pictorial review aims to illustrate the various manifestations of the diabetic foot on magnetic resonance (MR) imaging. The utility of MR imaging and its imaging features in the diagnosis of pedal osteomyelitis are illustrated. There is often difficulty encountered in distinguishing osteomyelitis from neuroarthropathy, both clinically and on imaging. By providing an accurate diagnosis based on imaging, the radiologist plays a significant role in the management of patients with complications of diabetic foot.
		                        		
		                        		
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Aged, 80 and over
		                        			;
		                        		
		                        			Cellulitis
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Diabetic Foot
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Gangrene
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Inflammation
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Osteomyelitis
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			physiopathology
		                        			;
		                        		
		                        			Risk Factors
		                        			;
		                        		
		                        			Skin Diseases
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Ulcer
		                        			;
		                        		
		                        			diagnosis
		                        			
		                        		
		                        	
3.Clinics in diagnostic imaging. 159. Jejunal intussusception due to Peutz-Jeghers syndrome.
Vijay KRISHNAN ; Ashish CHAWLA ; Eric WEE ; Wilfred C G PEH
Singapore medical journal 2015;56(2):81-quiz 86
		                        		
		                        			
		                        			A 21-year-old woman presented with acute onset of upper abdominal pain. A diagnosis of Peutz-Jeghers syndrome (PJS) was made based on the clinical picture of perioral pigmentation with imaging findings of transient jejunojejunal intussusceptions and small bowel polyps, and confirmed by characteristic histopathological appearances of Peutz-Jeghers polyps. PJS is a rare hereditary condition characterised by unique hamartomatous polyps, perioral mucocutaneous pigmentations, and increased susceptibility to gastrointestinal and extraintestinal neoplasms. Patients usually present with recurrent abdominal pain due to intussusception caused by polyps. Other modes of presentations include rectal bleeding and melaena. We describe the imaging findings of PJS and provide a brief review of bowel polyposis syndromes. The latter are relatively rare disorders characterised by multiple polyps in the large or small intestine, with associated risk of malignancies and other extraintestinal manifestations. Awareness of the manifestations and early diagnosis of these syndromes is crucial to prevent further complications.
		                        		
		                        		
		                        		
		                        			Abdominal Pain
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Barium
		                        			;
		                        		
		                        			chemistry
		                        			;
		                        		
		                        			Diagnostic Imaging
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intussusception
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Jejunum
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Peutz-Jeghers Syndrome
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Polyps
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			Young Adult
		                        			
		                        		
		                        	
5.Clinics in diagnostic imaging (162). Meckel's diverticulum.
Dinesh R SINGH ; Geoiphy G PULICKAL ; Zhiwen J LO ; Wilfred C G PEH
Singapore medical journal 2015;56(9):523-quiz 527
		                        		
		                        			
		                        			A 28-year-old Chinese man presented with acute bleeding per rectum. Computed tomography showed a posterior outpouching arising from the distal ileum. The outpouching had hyperaemic walls, but no active contrast extravasation was detected. Technetium-99m pertechnetate scintigraphy showed focal areas of abnormal uptake in the right side of the pelvis, superior and posterior to the urinary bladder. These areas of uptake appeared simultaneously with the gastric uptake and demonstrated gradual increase in intensity on subsequent images. The diagnosis of Meckel's diverticulum was confirmed on surgery and the lesion was resected. The clinical and imaging features of Meckel's diverticulum are discussed.
		                        		
		                        		
		                        		
		                        			Abdominal Pain
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Gastrointestinal Hemorrhage
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Ileum
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Meckel Diverticulum
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Radionuclide Imaging
		                        			;
		                        		
		                        			Radiopharmaceuticals
		                        			;
		                        		
		                        			Sodium Pertechnetate Tc 99m
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			
		                        		
		                        	
6.Clinics in diagnostic imaging (156). Golf-induced hamate hook fracture.
Hsien Khai TAN ; Nicholas CHEW ; Kelvin T L CHEW ; Wilfred C G PEH
Singapore medical journal 2014;55(10):517-quiz 521
		                        		
		                        			
		                        			The wrist is a common site of injury and the most frequently injured body part among professional golfers. A 37-year-old, right-handed male golfer presented with pain at the ulnar aspect of his left palm, which grew worse after an initial traumatic impact from the golf club handle. There was tenderness over the hypothenar eminence of the left palm. Computed tomography of the left wrist showed an undisplaced fracture through the base of the hamate hook. The golf-induced hamate hook fracture was managed conservatively, with cessation of physical activity involving the left hand and wrist for eight weeks. The patient made a full recovery. Repetitive trauma, exacerbated by improper wrist motion, leads to typical wrist injuries affecting golfers, such as ulnar impaction syndrome, de Quervain's disease, and tendinopathy affecting the flexor carpi ulnaris and extensor carpi ulnaris, all of which can be diagnosed on imaging.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Fractures, Bone
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Golf
		                        			;
		                        		
		                        			injuries
		                        			;
		                        		
		                        			Hamate Bone
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			injuries
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Tendinopathy
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Wrist Injuries
		                        			;
		                        		
		                        			diagnostic imaging
		                        			
		                        		
		                        	
7.Clinics in diagnostic imaging. 158. Duodenal ectopic pancreas.
Manickam SUBRAMANIAN ; Eric WEE ; Vijayadwaja DESAI ; Wilfred C G PEH
Singapore medical journal 2014;55(12):629-quiz 633
		                        		
		                        			
		                        			A 46-year-old man presented with right loin tenderness following a road traffic accident. Computed tomography and magnetic resonance imaging showed a well-defined, smooth, enhancing oval lesion in the wall of the first part of the duodenum. The lesion was seen separately from the normal pancreas. It showed attenuation, intensity and enhancement similar to that of normal pancreas. Based on the imaging appearance, a diagnosis of ectopic pancreas was made. The patient underwent oesophagogastroduodenoscopy, endoscopic ultrasonography and fine-needle aspiration cytology of the lesion, which confirmed ectopic pancreatic tissue. Since the patient was asymptomatic, surgical resection was deferred. The embryologic origin, various locations, imaging appearance and clinical significance of ectopic pancreas are discussed.
		                        		
		                        		
		                        		
		                        			Accidents, Traffic
		                        			;
		                        		
		                        			Choristoma
		                        			;
		                        		
		                        			congenital
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Contrast Media
		                        			;
		                        		
		                        			Duodenal Diseases
		                        			;
		                        		
		                        			congenital
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Endoscopic Ultrasound-Guided Fine Needle Aspiration
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Pancreas
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			;
		                        		
		                        			methods
		                        			
		                        		
		                        	
8.Clinics in diagnostic imaging (154). Carbon monoxide (CO) poisoning.
Puay Joo LIM ; Sumer Nrupendra SHIKHARE ; Wilfred C G PEH
Singapore medical journal 2014;55(8):405-quiz 410
		                        		
		                        			
		                        			A 59-year-old man with a history of major depression was found by his wife to be unconscious and foaming at the mouth. On arrival at the emergency department, the patient was noted to be unresponsive. Computed tomography of the brain showed symmetrical ill-defined areas of hypoattenuation involving the medial aspects of both lentiform nuclei, while magnetic resonance images of the brain showed symmetrical increased signal in the bilateral globi pallidi on diffusion weighted, T2-weighted and fluid attenuated inversion recovery sequences. These findings were those of acute carbon monoxide poisoning. Despite aggressive treatment, the patient's condition continued to deteriorate and he eventually passed away. The various imaging findings of carbon monoxide poisoning in the brain and the differential diagnoses are discussed.
		                        		
		                        		
		                        		
		                        			Brain
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Carbon Monoxide Poisoning
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Depressive Disorder, Major
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			Diagnostic Imaging
		                        			;
		                        		
		                        			Fatal Outcome
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Pulmonary Edema
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Radiography, Thoracic
		                        			;
		                        		
		                        			Suicide, Attempted
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			
		                        		
		                        	
9.Clinics in diagnostic imaging (152). Right lower lobe segmental pulmonary embolus.
Jerome Irai Ezhil BOSCO ; Ree Nee KHOO ; Wilfred C G PEH
Singapore medical journal 2014;55(5):281-286
		                        		
		                        			
		                        			A 56-year-old man presented to the Accident and Emergency Department with pleuritic chest pain of sudden onset. He gave a history of short-distance air travel ten days earlier. Chest radiograph showed a peripheral-based opacity in the right lower zone, which was not seen in a previous study done three months ago, suggestive of Hampton's hump. The D-dimer level was raised. Computed tomography pulmonary angiography confirmed the diagnosis of pulmonary embolism in a right lower lobe segmental branch, with adjacent collapsed lung, consistent with lung infarction. The patient was started on heparin injection with significant relief of his symptoms. The clinical and imaging features of pulmonary embolism are described, with emphasis on the historical radiographic signs and the current dual-energy computed tomography innovations.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Angiography
		                        			;
		                        		
		                        			Chest Pain
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Fibrin Fibrinogen Degradation Products
		                        			;
		                        		
		                        			metabolism
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Lung
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Pulmonary Embolism
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			Radiography, Thoracic
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			
		                        		
		                        	
10.Clinics in diagnostic imaging. 145.
Jerome Irai Ezhil BOSCO ; Albert S C LOW ; Damien M Y TAN ; Wilfred C G PEH
Singapore medical journal 2013;54(4):231-quiz 235
		                        		
		                        			
		                        			A 63-year-old man presented with painless jaundice, loss of appetite and significant weight loss. Cross-sectional imaging showed a diffusely enlarged pancreas, with no significant fat stranding and a hypodense rim on computed tomography, which appeared hypointense on T2-weighted magnetic resonance imaging. There was a narrowed pancreatic duct and features of common bile duct narrowing in the region of the pancreatic head. However, there was no obvious mass seen in the pancreatic head region. These features were classical of autoimmune pancreatitis with diffuse involvement of the gland. Laboratory investigation showed abnormal liver function and the classical sign of raised immunoglobulin G class 4 antibodies. The patient showed dramatic response to high-dose steroids, with resolution of both the laboratory and imaging abnormalities within one month. We discuss the classical imaging features of Type 1 autoimmune pancreatitis, an uncommon condition that needs to be differentiated from pancreatic malignancy.
		                        		
		                        		
		                        		
		                        			Autoimmune Diseases
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Diagnostic Imaging
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Jaundice
		                        			;
		                        		
		                        			complications
		                        			;
		                        		
		                        			diagnosis
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Pancreas
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Pancreatitis
		                        			;
		                        		
		                        			diagnostic imaging
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Tomography, X-Ray Computed
		                        			
		                        		
		                        	
            
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