Objective:To investigate the blood pressure control and its influencing factors in hypertension patients with MS.Methods:Between January 2017 and December 2018, more than 78 000 residents aged 35-75 years selected through convenient sampling were invited to participant in China Patient-Centered Evaluative Assessment of Cardiac Event Million Persons Project in Fujian province, physical and laboratory tests were conducted for them, and their basic information were recorded. A total of 5 281 hypertension patients with MS were included in the study.Results:The treatment rate of hypertension patients with MS was 55.5%, and the control rate was 7.2%. The control rate was higher in patients who were older, women, had advanced education level, had history or family history of cardiovascular disease. The results of multivariate analysis indicated that living area (urban or rural), cardiovascular history, diabetes, urine protein, BMI had impacts on both treatment and control of hypertension. Family history of cardiovascular disease, age, self-management of hypertension, dyslipidemia, waist circumference and drinking had impacts on the treatments, and gender had effects on the control.Conclusions:The treatment rate of hypertension patients with MS was unsatisfactory and the control rate was low. Intervention should be strengthened in rural area, males and young age groups, and activity of self-management group of hypertension should be conducted regularly.

Objective: To investigate the association between acute global coronary event registration(GRACE) risk score and laboratory parameters in patients with acute myocardial infarction(AMI). Methods: A retrospective analysis of 128 patients with AMI who admitted in Wenling Hospital of Traditional Chinese Medicine from May 2014 to May 2016 was performed.Among them, 86 patients with ST-segment elevation myocardial infarction were included in A group, and 42 patients with non-ST-segment elevation myocardial infarction were included in B group.According to the GRACE score at admission, they were divided into low, medium and high risk groups.The correlation between the patients' GRACE score and laboratory indicators was analyzed. Results: There were statistically significant differences in gender, alcohol consumption, age, PRBC and GRACE scores between A group and B group(χ²=4.071, 4.096, t=3.594, 2.378, 2.657, all P<0.05). According to age, GRACE and PRBC, the area under the ROC curve was 0.738(95% CI: 0.603~0.765, P<0.05). The male, smoking, drinking, age, D-dimer, PRBC, FDP, RDW and MCV had statistically significant differences among the low, medium and high risk groups(χ²=8.225, 11.450, 3.739, F=73.311, 146.980, 86.414, 10.512, 3.981, 5.786, all P<0.05). The correlation analysis showed that the GRACE score had positive correlation with age, MPV, PCT, MCV, RDW, PRBC, FDP and D-dimer (r=0.712, 0051, 0.128, 0.134, 0.039, 0.157, 0.279, 0.286, all P<0.05). The multiple linear regression analysis showed that the independent risk factors for GRACE scores were age and FDP. Conclusion There are significant differences in age, gender, drinking history, PRBC and GRACE scores between ST-segment elevation myocardial infarction patients and non-ST-segment elevation myocardial infarction patients, and there is a significant correlation between GRACE scores and laboratory test indicators.

Kidney stones are a common urinary system condition that can progress to kidney disease. Previous studies on the association between tea consumption and kidney stones are inconsistent. A cross-sectional study to investigate the association between tea consumption and kidney stones was conducted from 2013 to 2014 and recruited 9,078 northern Chinese adults. A total of 8,807 participants were included in the final analysis. Participants' prevalence of kidney stones was 1.07%, 1.73%, and 2.25% based on their tea consumption frequency of never, occasionally, and often groups, respectively. Compared with the 'never' group, the odds ratios (95% confidence intervals) for the occurrence of kidney stones were 1.57 (1.00-2.46) and 1.65 (1.06-2.57) in the 'occasionally' and 'often' groups, respectively. After adjusting for sex, age, and other potential confounding factors, tea consumption still significantly increased the risk of kidney stones. Tea consumption is independently associated with an increased risk of kidney stones in the investigated population, suggesting that a decrease in the consumption of tea may be a preventive strategy for kidney stones.

OBJECTIVETo determine the risk factor of HCC in Guizhou.

METHODSA group case-control study design was conducted between 762 cases and 798 controls in Guizhou province. The main related-factors were analyzed with unconditional logistic regression model and evaluated by odds ratio (OR) and 95% confidence interval (95% CI).

RESULTSThere are significant differences between cases and controls in regarding to cigarette smoking 210 (27.6%),non-alcoholic fatty liver disease 336 (44.1%), alcoholic liver disease 245 (32.2%), family history of HCC 141 (16.5%), alcohol consumption 300 (39.4%), HBV infection 436 (57.2%), pickled food 290 (38.1%), and economic status 5 years ago 420 (55.1%) in cases,and cigarette smoking 116 (14.5%),non-alcoholic fatty liver disease 160 (20.1%), alcoholic liver disease 101 (12.7%), family history of HCC 40 (5.0%), alcohol consumption 180 (22.6%), HBV infection 82 (10.3%), pickled food 225 (28.2%), and economic status 5 years ago 647 (81.1%) in controls, with OR of each variable was 3.520, 2.464, 4.330, 2.219, 2.451, 19.245, 6.212, 0.174 respectively, P less than 0.01.

CONCLUSIONHBV infection and pickled food were the most common risks for HCC in Guizhou. Alcohol consumption excessively and cigarette smoking may increase the risk too.

Adult ; Aged ; Aged, 80 and over ; Alcohol Drinking ; Carcinoma, Hepatocellular ; epidemiology ; etiology ; Case-Control Studies ; China ; epidemiology ; Feeding Behavior ; Female ; Hepatitis B ; epidemiology ; Humans ; Liver Neoplasms ; epidemiology ; etiology ; Male ; Middle Aged ; Risk Factors ; Young Adult

Objective To analyze the change of life expectancy (LE) among residents of Fujian province over the past two decade and to evaluate the impact of age and causes of death on the differences related to LE.Methods Mortality data from Causes of Death Surveillance System of Ministry of Health in Fujian province during 1990-2010 were used to calculate the life expectancy,and Arriaga decomposition method was applied to quantitatively evaluate its changes,based on the age-specific and cause-specific mortality.Results The LE in urban and rural residents of Fujian province had an increase of 5.82 and 11.67 years during the past two decade,respectively,which were higher in urban residents than in rural residents.Although the increment of LE was higher in rural populations than in urban population,the difference of LE between urban and rural was seen narrowed.The contribution rate of children on LE was reducing and the contribution rate of children below 14 years old to LE in rural resident declined from 78.29％ to 31.23％.Middle age and elderly populations had become the major ones that causing the change of LE.The impact of cancer,respiratory diseases and cerebrovascular diseases on LE in urban residents was reducing,while the influence of infectious disease,nervous system disease and cardiac disease was increasing,causing the LE of urban resident increased 1.54,0.67 and 0.49 years,respectively.The impact of respiratory diseases,digestive system diseases,as well as injury and poisoning on LE in the rural residents was reducing,while the effect of cancer,cerebrovascular and cardiac disease increased,causing the LE in the rural resident increased 1.23 years.Different causes of death had different impact on the LE in each age group.Conclusion To reduce the mortality rate in the middle-aged and elderly population and to control the incidence of non-communicable diseases could help to improve the LE in the residents of Fujian province.

Objective To explore the association of sedentary life style with risk of metabolic syndrome (MS) and diabetes mellitus type 2 (T2DM).Methods A total of 6 016 local residents aged 18 years or older in Fujian province were recruited by multi-stage stratified cluster sampling method in 2010-2011.Data,including demographic information,physical activity and sedentary time were collected.Indices related to height,weight,waist circumference,blood pressure and blood lipid were determined while MS and T2DM were diagnosed by IDF (2005) and WHO (1999) criteria.Logistic regression was used to estimate the correlations between sedentary behavior and MS or T2DM.Results The prevalence rates of MS and T2DM were 19.0％ and 8.0％ respectively,in local residents aged 18 years or older,in Fujian province.The overall rate of sedentary behavior was 18.1％,with the mean sedentary time as 4.3 hours.Both data showed significantly differences (P＜0.001) among control group,MS without T2DM group,MS with T2DM group and T2DM without MS group.Compared with the group of sedentary time ＜2.0 h/d,1) the group with 2.0-3.5 h/d was significantly correlated with MT group (OR=1.44,95％ CI:1.03-2.03,P＜0.05),2) groups of 3.5-6.0 h/d and ≥6.0 h/d were significantly correlated with M,T,MT group,respectively (OR:1.49-1.76 and 1.28-1.58 respectively,95％ CI:1.19-2.45 and 1.02-2.23 respectively,P＜ 0.05),and 3) sedentary behavior was independently associated with an increased risk of MT group (OR=1.82,95％ CI:1.33-2.48,P＜0.01) and M group (OR=1.43,95％CI:1.14-1.78,P＜0.01),after the adjustment for factors as age,sex,cigarette smoking,alcohol drinking,BMI,education,occupation,sedentary behavior/sedentary time.Conclusion MS and T2DM were associated with sedentary lifestyle,but these findings should be confirmed through further longitudinal studies.

OBJECTIVETo evaluate the clinical effects of combined methods of minimally invasive percutaneous proximal humeral internal locking system (PHILOS) and injectable bone for the treatment of proximal humerus fractures in elderly patients.

METHODSFrom January 2006 to January 2012, 80 patients with proximal humerus fractures were randomly divided into two groups (n = 40). The patients in the research group were treated with minimally invasive PHILOS fixation combined with injectable bone, including 20 males and 20 females, with an average age of (68.4 +/- 11.9) years; according to AO classification, 2 cases of type A1, 3 cases of type A2, 6 cases of type B1, 7 cases of type B2, 9 cases of type B3, 6 cases of type C1, 7 cases of type C2. The patients in the control group were treated with PHILOS fixation, including 18 males and 22 females, with an average age of (65.4 +/- 10.7) years; according to AO classification, 3 cases of type A1, 4 cases of type A2, 5 cases of type B1, 8 cases of type B2, 10 cases of type B3, 5 cases of type C, and 5 cases of type C2. The BMD, satisfactory rate, postoperative complications,bone healing time, Constant-Murley score in the two groups were reviewed and compared.

RESULTSIn the research group, no patients had necrosis of femoral head, 1 patient had shoulder varus, 1 patient had internal fixation loosening, 36 patients were satisfactory with the treatment results, BMD was (1.013 +/- 0.109) g/cm2, bone healing time averaged (12.00 +/- 3.79) weeks, and the Constant-Murley score was 97.2 +/- 4.6. In the control group, 3 patients had necrosis of femoral head, 5 patients had shoulder varus, 6 patients had internal fixation loosening, 32 patients were satisfactory with the treatment results, BMD was (0.812 +/- 0.089) g/cm2, bone healing time averaged (20.00 +/- 8.67) weeks,and the Constant-Murley score was 78.5 +/- 3.2. The results of BMD, satisfactory rate, postoperative complications, bone healing time, and Constant-Murley score in the research group were better than those of control group (P < 0.05).

CONCLUSIONPHILOS combined with injectable bone for the treatment of proximal humerus fractures in elderly patients has advantages of minimal wound, stable fixation, and earlier rehabilitation.

Aged ; Bone Plates ; Female ; Fracture Fixation, Internal ; methods ; Humans ; Humerus ; surgery ; Injections ; Male ; Middle Aged ; Retrospective Studies ; Shoulder Fractures ; surgery ; Treatment Outcome