1.Application value of intracranial arterial calcification in mechanical thrombectomy for acute ischemic stroke
Xin LI ; Wenjuan LANG ; Xiaoliang WANG
Journal of Apoplexy and Nervous Diseases 2024;41(10):928-932
Objective To investigate the modified Woodcock score of intracranial arterial calcification(IAC)in acute ischemic stroke patients with intracranial large or medium vessel occlusion and its impact on the outcome of endovascular treatment and surgery.Methods The patients who underwent mechanical thrombectomy for acute isch-emic stroke due to large or medium vessel occlusion in our hospital from January 2017 to July 2021 were enrolled,and related demographic and clinical variables were analyzed,including age,sex,and National Institutes of Health Stroke Scale(NIHSS).Pearson correlation analysis,linear regression analysis,and logistic regression analysis were used for modeling to determine the association between symptomatic IAC and outcome,and the variables that were sig-nificantly associated with outcome were used for adjustment,with P<0.05 as statistically significant.Results Of all acute ischemic stroke patients,74(53.6%)were found to have intracranial vascular calcification on CT images on admission.The modified Woodcock score on the ipsilateral side of the diseased vessels had a certain value in predict-ing the prognosis of mechanical thrombectomy for large vessel occlusion,and the logistic regression analysis showed that calcification score on the ipsilateral side was negatively correlated with the modified Rankin Scale(mRS)score(P=0.026),and the use of balloons was positively correlated with mRS score(P=0.035).Data analysis showed that the patients with a high level of low-density lipoprotein(LDL)tended to have high total hospital costs,high costs of surgical materials,a high possibility of stent implantation,and a low recanalization rate.Conclusion Intracranial arterial calcification score has a certain application value in mechanical thrombectomy for acute ischemic stroke.Pa-tients with high LDL tend to have high total hospital costs,high costs of surgical materials,a high possibility of stent implantation,and a low recalculation rate after surgery.
2.Clinical prognosis of patients with acute ischemic stroke and its application value were evaluated using 3D CUBE T1 high resolution imaging and magnetic sensitivity techniques
Xin LI ; Wenjuan LANG ; Kai SHI
Journal of Apoplexy and Nervous Diseases 2020;37(5):393-397
Objective Clinical prognosis and clinical application value of patients with acute ischemic stroke were evaluated using magnetic resonance 3D CUBE T1 high resolution vascular wall imaging and magnetic sensitive vascular signs (SVS). Methods Demographic data and imaging characteristics of patients with acute ischemic stroke with in 24 hours were collected to evaluate the NIH Stroke Scale (NIHSS) and the modified Rankin Scale. The risk factors of 3D CUBE T1 high signal and SVS (dual-symptom group) were found by binary logistic regression analysis,and whether there a difference between NIHSS score at admission and discharge time and the score of modified Rankin scale 3 months later. Results No risk factors associated with MRA occlusion or dual-sign group were found by binary logistic regression analysis. When the NIHSS score was compared at 7 days’ discharge,it was found that the patients in the MRA group (P=0.007) and the double-sign group (P=0.010) had higher NIHSS score and heavier clinical manifestations. By comparing the modified Rankin scores of the patients 3 months after discharge,it was found that the patients in the MRA group (P=0.019) and the dual-sign group (P=0.026) had worse prognosis at 3 months. At the same time,the data showed that there was a good consistency between dual-sign and MRA in assessing the severity of symptoms and prognosis of patients (P=0.996 for comparison of NIHSS score and P=0.912 for the modified Rankin Scale score). Conclusion In patients with acute ischemic stroke,the combination of 3D CUBE T1 sequence high signal and magnetic sensitive vascular signs of thrombosis can better determine and predict the prognosis of patients. Meanwhile,patients with 3D CUBE T1 high signal and magnetic sensitive vascular signs (SVS) have higher NIHSS score at discharge and worse prognosis after 3 months. Compared with the MRA group,the combination of 3D CUBE T1 sequence high signal and magnetic sensitive vascular signs of thrombosis has a better consistency in the assessment of patients’ clinical manifestations and prognosis,which is worthy of clinical technology promotion and application.
3. Recognition of the breach rhythm
Jiang ZHU ; Lang JIN ; Bi WANG ; Xiaoli WANG ; Beibei CHEN ; Wenjuan ZHANG ; Yonghong LIU
Chinese Journal of Neurology 2019;52(12):1078-1080
Breach rhythm was firstly described in 1979, and is considered as a rare benign variant of electroencephalogram. The etiology, electroencephalogram features and evaluation of breach rhythm, and so on, are discussed in this article.
4.Influence of electroacupuncture pretreatment on intestinal function in the patients of colorectal cancer surgery.
Sicong MAI ; Jinhai MENG ; Wenjuan WANG ; Shuhui LANG
Chinese Acupuncture & Moxibustion 2017;37(5):483-487
OBJECTIVETo observe the effects of electroacupuncture (EA) pretreatment on the intestinal function, inflammatory reaction and blood lactic acid in the patients of colorectal cancer surgery.
METHODSSixty patients of colorectal cancer laparotomy at selective period, aged from 18 to 59 years old were selected. According toⅠ-Ⅲ grade of American Society of Anesthesiologists (ASA), the patients were randomized into group A (total intravenous anesthesia), group B[total intravenous anesthesia combined with EA pretreatment at Zusanli (ST 36), Shangjuxu (ST 37) and Xiajuxu (ST 39) on the right side] and group C[total intravenous anesthesia combined with EA pretreatment at Zhongwan (CV 12), Tianshu (ST 25), Zusanli (ST 36), Shangjuxu (ST 37) and Xiajuxu (ST 39) on the right side], 20 cases in each one. The total intravenous anesthesia was applied to all of the three groups. EA pretreatment was used one day before surgery and 30 min before surgery at corresponding acupoints in the group B and group C separately, 30 min each time. After surgery, the recovery time of bowel sound, the recovery time of flatus, the recovery time of defecation, the duration of diet fasting, the time of peritoneal drainage tube withdrawal and the total peritoneal drainage volume were observed in the three groups. The venous blood was collected to determine white blood cell count (WBC) and neutrophil count (NEUT) before surgery (T), 24 h after surgery (T) and on the 5th day after surgery (T) separately. The arterial blood was collected to determine the level of lactic acid before surgery (T), after peritoneal douching (T) and 24 h after surgery (T)separately.
RESULTSThe recovery time of bowel sound, the recovery time of flatus, the duration of diet fasting and the time of peritoneal drainage tube withdrawal in the group C were apparently earlier than those in the group A (all<0.05). WBC and NEUT at Tin the group C were apparently less than those in the group A (both<0.05). The differences in lactic acid at T, Tand Twere not significant statistically in comparison of the three groups (all>0.05).
CONCLUSIONSThe total intravenous anesthesia combined with EA pretreatment at Zusanli (ST 36), Shangjuxu (ST 37), Xiajuxu (ST 39), Tianshu (ST 25) and Zhongwan (CV 12) reduce the recovery time of bowel sound, the recovery time of flatus, the duration of diet fasting and the time of peritoneal drainage tube withdrawal so as to improve the recovery of intestinal function, reduce WBC in 24 h after surgery and alleviate inflammatory reaction. This therapy has no influence on blood lactic acid.


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