OBJECTIVES: To assess the inadvertent intraocular retention of perfluorocarbon liquid (PFCL) after vitreoretinal surgery and their complications. METHODS: We retrospectively reviewed the medical records of 108 patients who underwent vitreoretinal surgeries using intraoperative PFCL (perfluoro-n-octane (C8F18), 0.69 centistoke at 25degrees C, PERFLUORN(R), Alcon, USA) and the removal of PFCL through fluid-air exchange. The analysis was focused on the occurrence of intraocular retained PFCL, diagnoses,surgicalprocedures,andcomplications. RESULTS: Retinal detachment (51 cases, 47%) was the most common surgery which used PFCL intraoperatively. Other causes were vitreous hemorrhage (24 cases, 22%), posteriorly dislocated lens (22 cases, 21%), and trauma (11 cases, 10%). Intraocular PFCL was found in a total of 9 (8.3%) eyes. PFCL bubbles remained in anterior chamber and vitreous cavity were observed in 4 cases and subretinal retained PFCL was observed in 5 cases. Three of 5 cases of subretinal PFCL exhibited in subfoveal space. Among the three subfoveal cases, macular hole developed after PFCL removal in 1 case, epiretinal membrane in the area where had been PFCL bubble. However, we observed no complications in 1 case of subfoveal PFCL that was removed by surgery. PFCL in anterior chamber and vitreous cavity were in 4 cases. CONCLUSIONS: The presence of subfoveal PFCL might affect visual and anatomic outcomes. However, subfoveal PFCL may induce visual complications, and therefore requires special attention.
Anterior Chamber ; Epiretinal Membrane ; Humans ; Medical Records ; Retinal Detachment ; Retinal Perforations ; Retrospective Studies ; Vitrectomy* ; Vitreoretinal Surgery ; Vitreous Hemorrhage

BACKGROUND: The purpose of this study was to evaluate the effect of intraoperative dexmedetomidine sedation on patient's and surgeon's satisfaction during retinal surgery under sub-tenon's anesthesia. METHODS: Forty-four patients scheduled for elective retinal surgery under sub-tenon's anesthesia were enrolled in this randomized controlled trial. The patients were divided into Dexmedetomidine (n = 22) and Control (n = 22) groups. Intravenous dexmedetomidine or 0.9% saline via infusion pump were administered continuously to the dexmedetomidine or control group, respectively. Ramsay sedation scale with a target level of 3-4 was used to assess adequacy of sedation. Perioperative pain, hemodynamic and respiratory data were collected, while satisfaction from patients and surgeon were assessed post-surgery using a 5-point satisfaction scale. RESULTS: Patient and surgeon satisfaction was higher in the dexmedetomidine group (P < 0.001, P = 0.002, respectively). The pain associated with sub-tenon's anesthesia and peripheral vitrectomy was lesser in the dexmedetomidine group than in the control group (P = 0.020). There was significant reduction of heart rate in the dexmedetomidine group (P = 0.001), but only one patient needed treatment with atropine. There was no respiratory effect on both groups. CONCLUSIONS: Dexmedetomidine sedation during retinal surgery improved satisfaction from both patient and surgeon without respiratory complication. It is a safe and preferable choice of sedation for retinal surgery.
Anesthesia* ; Atropine ; Conscious Sedation ; Dexmedetomidine* ; Heart Rate ; Hemodynamics ; Humans ; Infusion Pumps ; Patient Satisfaction ; Retinaldehyde* ; Vitrectomy ; Vitreoretinal Surgery

PURPOSE: To evaluate the risk factors for the development of posterior capsule opacification (PCO) after cataract surgery or combined cataract and vitreoretinal surgery. METHODS: In the present study all surgical procedures were performed by the same surgeon. We retrospectively reviewed 272 consecutive eyes that received cataract surgery or combined cataract and vitreoretinal surgery. The risk factors including gender, age, diabetes, continuous curvilinear capsulorhexis (CCC) size, intraocular lens shape, intraoperative intravitreal bevacizumab, gas, and silicone oil injections were evaluated using multiple logistic regression analysis. RESULTS: PCO developed in 55 (20.2%) out of 272 eyes. The mean age was 63.3 +/- 12.1 years (range 23-85 years) and mean follow-up period was 17.3 +/- 3 months. A correlation existed between the development of the PCO and age (p < 0.05), CCC size (p = 0.009), vitreoretinal surgery (p = 0.014), intraoperative intravitreal gas (p = 0.009) and silicone oil injections (p = 0.005). However, no statistical correlation with gender, diabetes, intraocular lens shape, or intraoperative intravitreal bevacizumab injection was observed (p > 0.05). CONCLUSIONS: The risk factors associated with PCO included young age, large CCC size, combined cataract and vitreoretinal surgery, intraoperative intravitreal gas and silicone oil injections.
Capsule Opacification* ; Capsulorhexis ; Cataract* ; Follow-Up Studies ; Lenses, Intraocular ; Logistic Models ; Retrospective Studies ; Risk Factors* ; Silicone Oils ; Vitreoretinal Surgery* ; Bevacizumab

Adolescent ; Adult ; Child ; Eye Foreign Bodies ; surgery ; Eye Injuries, Penetrating ; complications ; Fluoroscopy ; Humans ; Male ; Middle Aged ; Orbit ; surgery ; Retrospective Studies ; Vitreoretinal Surgery

OBJECTIVETo examine the hyperglycemic effects of periocular dexamethasone injection in type 2 diabetic patients after vitreoretinal surgery (VRS).

METHODSThis was a retrospective non-randomized controlled trial. Twenty consecutive hospitalized patients with type 2 diabetes and ocular inflammatory reaction after VRS were enrolled in this study. Ten patients received 2.5 mg dexamethasone and 10 patients received 5 mg dexamethasone. Fourteen consecutive type 2 diabetic patients without ocular inflammatory reaction after VRS were used as control group. We measured fasting blood glucose (FBG) and at 2 h after each meal (post prandial glucose, PBG; 09:00, 13:00, and 19:00 h) after periocular dexamethasone injection. Differences among three groups were determined by q tests.

RESULTSThe PBG levels in both dexamethasone-treated groups started to increase within 5 h after injection (i.e., PBG at 13:00 h), and were significantly increased at 19:00 h after injection (P<0.05). BG levels were almost 2-fold higher than at baseline and compared with the control group. The BG values declined gradually by 24 h to 48 h after injection. There were no differences in BG levels between the two dexamethasone-treated groups (P>0.05), except for PBG at 19:00 h on day 2 after injection (P<0.05).

CONCLUSIONPeriocular dexamethasone injection can cause transient hyperglycemia in diabetic patients after VRS. BG monitoring should be performed following such injection.

Anti-Inflammatory Agents ; administration & dosage ; adverse effects ; Dexamethasone ; administration & dosage ; adverse effects ; Diabetes Mellitus, Type 2 ; blood ; Humans ; Hyperglycemia ; chemically induced ; Injections, Intraocular ; Retrospective Studies ; Vitreoretinal Surgery

PURPOSE: To analyze retinal tears and to compare the clinical outcomes between retinal tear and rhegmatogenous retinal detachment (RRD) as the cause of dense non-diabetic vitreous hemorrhage in patients who underwent vitreoretinal surgery. METHODS: In a retrospective case series, the medical records of patients who presented dense non-diabetic vitreous hemorrhage and who underwent vitreoretinal surgery between January 2005 and June 2009 were reviewed. Among the 134 patients, 27 patients had dense vitreous hemorrhage caused by retinal tears. The first group had retinal tears only and the second group had accompanying RRD. A comparison of clinical features and postoperative prognoses between the two groups was performed. RESULTS: Among the 27 eyes with non-traumatic retinal tear and RRD, 18 were categorized into the retinal tear group and 9 to the RRD group. The demographic findings between the two studied groups exhibited no significant differences except for time between onset of symptoms and diagnosis. However, the time to diagnosis was significantly delayed in the group with RRD (22.67 +/- 37.47 days) compared to the retinal tear group (5.00 +/- 3.41 days) (p = 0.035). The amount of visual improvement was also greater in the retinal tear group than the RRD group (p = 0.002). CONCLUSIONS: Retinal tears are a major cause of non-diabetic vitreous hemorrhage. Vitreous hemorrhage caused by retinal detachment may result in delayed diagnosis and poor visual recovery. Therefore, early examinations in suspicion of RRD and appropriate treatments are needed in non-diabetic vitreous hemorrhage.
Delayed Diagnosis ; Eye ; Humans ; Medical Records ; Prognosis ; Retinal Detachment ; Retinal Perforations ; Retinaldehyde ; Retrospective Studies ; Vitreoretinal Surgery ; Vitreous Hemorrhage

PURPOSE: To investigate the incidence and risk factors of major complications including postoperative hypotony after 23-gauge transconjunctival sutureless vitrectomy in previously vitrectomized eyes. METHODS: The authors retrospectively reviewed medical records of 52 eyes, which underwent 23-gauge transconjunctival sutureless vitrectomy of previously vitrectomized eyes by a single surgeon. Major outcomes were postoperative hypotomy (<6 mmHg), intraoperative sclera shrinkage during sclerotomy,and other postoperative complications. Multiple logistic regression analysis was performed that included 212 eyes with primary vitreoretinal surgery in order to validate secondary vitreoretinal surgery as a significant risk factor of postoperative hypotony. RESULTS: Postoperative hypotony occurred in 4 eyes (7.7%) out of 52 eyes that underwent a second vitrectomy. The odds ratio of the second vitreoretinal surgery (OR=1.15, p=0.283) was not significant by multiple logistic regression analysis that included age, sex, axial length of globe, and the number of surgeries as the independent variables. Choroidal detachment occurred in one eye but disappeared three days later. The intraocular pressure was normalized within one week in all cases. Scleral shrinkage during sclerotomy occurred in five eyes (9.6%), and there were no other major complications, such as endophthalmitis. CONCLUSIONS: A 23-gauge transconjunctival sutureless vitrecomy of previously vitrectomized eyesshowed a 7.7% incidence of postoperative hypotony and favorable prognosis.
Choroid ; Endophthalmitis ; Eye ; Incidence ; Intraocular Pressure ; Logistic Models ; Medical Records ; Odds Ratio ; Postoperative Complications ; Prognosis ; Retrospective Studies ; Risk Factors ; Sclera ; Vitrectomy ; Vitreoretinal Surgery

PURPOSE: A corneal epithelial debridement using three different instruments was performed in rabbits, and the rates of corneal epithelium recovery were compared. Additionally, the extent of corneal damage as determined by the scanning electron microscopy was evaluated in each group. METHODS: Nineteen eyes of ten rabbits were classified into three groups according to the instruments used. The corneal epithelial debridement was performed using three different instruments: a Beaver blade (group A), a Bard-Parker blade No.15 (group B) and a dry cotton-tipped ap plicator (group C). After epithelial debridement, each cornea was observed every 24 hours for three days. After completion of the corneal recovery, each cornea was severed along the limbus and observed under the scanning electron microscope. RESULTS: The rate of corneal epithelial healing of the group C (dry cotton-tipped applicator) showed no statistical significance from those of the other groups. However, according to the corneal status observed under scanning electron microscope after debridement, cracks in the corneal surface in portions of group A and B were observed in contrast with no creaks in group C. CONCLUSIONS: Based on these results, corneal epithelial debridement using a cotton-tipped applicator is expected to reduce the occurrence of postoperative corneal complications. Use of a dry cotton-tipped applicator for corneal epithelial debridement in vitreoretinal surgery is suggested.
Cornea ; Debridement ; Electrons ; Epithelium, Corneal ; Eye ; Microscopy, Electron, Scanning ; Rabbits ; Rodentia ; Vitreoretinal Surgery

PURPOSE: To evaluate clinical analyses & risk factors for retinal detachment after silicone oil removal in the eyes with completely stable retinal state. METHOD: The authors retrospectively analyzed the clinical diagnosis, timing of retinal detachment, operative record, and final anatomic success of 10 consecutive eyes with retinal detachment after silicone oil removal. RESULTS: The retinal detachment group after silicone oil removal consisted of 3 eyes with proliferative vitreoretinopathy, 3 eyes with proliferative diabetic retinopathy, 3 eyes with the retinal detachment with macular hole and 1 eye with traumatic rhegmatogenous retinal detachment. Retinal detachment occurred from 1 to 17 weeks after the silicon oil removal surgery. The retinal detachments were associated with reopening of old breaks (5 eyes), new retinal breaks (3 eyes), vitreoretinal tractions (2 eyes). The retina was completely or partially reaatached after additional vitreoretinal surgery in 9 eyes, but total retinal detachment occurred in 1 eye due to reattachment operation rejection. CONCLUSIONS: The retinal break with remained vitreous traction and the proliferative membrane appeared to be an important factor in retinal detachments after silicone oil removal. Therefore, potential retinal breaks and complete removal of vitreous and tractional force during intraocular surgery should be considered.
Diabetic Retinopathy ; Eye ; Membranes ; Rejection (Psychology) ; Retina ; Retinal Detachment ; Retinal Perforations ; Retinaldehyde ; Retrospective Studies ; Risk Factors ; Silicone Oils ; Traction ; Vitreoretinal Surgery ; Vitreoretinopathy, Proliferative

OBJECTIVE: To evaluate the characteristics, safety and therapeutic effect of cataract phacoemulsification after vitreoretinal surgery. METHODS: We retrospectively reviewed 132 patients (132 eyes) which had phacoemulsification after vitreoretinal surgery between July 2001 and December 2004 in our hospital, among which 67 patients (50.75%) combined with silicon oil removal.We also analyzed the difficulties and complications of the surgery. RESULTS: Patients were followed up for 7-14 months.Three eyes with broken suspensory ligaments were implanted with one point transcleral fixed intraocular lens(iol).Corrected visual acuity improved in 123 patients (93.18%), no change in 6 patients (4.54%), and visual acuity loss in 3 patients (2.27%). CONCLUSION Cataract surgery is high difficult after the vitreoretinal surgery. Phacoemulsification can easily adjust and control intraocular pressure, simplify the operation,and reduce complications during and after the surgery. Silicon oil removal combined with cataract phacoemulsification is safe and economic.
Adolescent ; Adult ; Aged ; Cataract ; etiology ; Cataract Extraction ; methods ; Child ; Female ; Humans ; Male ; Middle Aged ; Phacoemulsification ; Retrospective Studies ; Vitreoretinal Surgery ; adverse effects ; Young Adult