Background and rationale: The Institute of Higher Education in Medical Sciences has a key role to play in the made of personnel in response to strategic plans for optimizing health worker staffing. Student participation is an important element in helping to develop the characteristics of a comprehensively able student. Objective: To study the students’ participation towards students ‘activities at the University of Health Sciences. Methodology: This study was a cross-sectional descriptive study of year 1 – 3 students who gave consent to study. Data were collected by using questionnaires during face-to-face interviews. The data were entered in Epi-data and analyzed by SPSS. Results: Of a total of 331 participants, more than half (63.1%) were female. The students’ participation to activities were high (X̅= 3.88 over 5, S.D= 0.54). When considering for each componente, it was found thatn the participation to the academic promotion was high level (X̅= 3.80, S.D= 0.58), to the sports events was at high level ((X̅= 3.91, S.D= 0.65), to the cultural arts was also at high level (X̅= 3.87, S.D= 0.70), and to the volunteer aspect was high level (X̅ = 3.94, S.D= 0.65). Gender segregation for each participation was not statistically significant at the 0.05 level. Conclusion The students from faculties have different opinions on participation to extra-curriculum activities particularly on the promotion of academics, sports, arts and culture, with the exception of volunteers.