1.Endoscopic and histopathological characteristics of polyp and colorectal cancer in people with a family history of colorectal cancer
Nhuan Quy BUI ; Thi Khanh Tuong TRAN
Hue Journal of Medicine and Pharmacy 2023;13(7):9-14
Background: According to Globocan statistics in 2018, there were estimated 1.8 million cases of colorectal cancer and 881,000 deaths. The rate of colorectal cancer is tending to increase in people under 50 years old. According to the 2017 American Society for Gastrointestinal Endoscopy guidelines, Colonoscopy every 5 years beginning 10 years before the age at diagnosis of the youngest affect interval or age 40, whichever is earlier; for those with a single first-degree relative with colorectal cancer in whom no significant neoplasia appears by age 60 years, physicians can offer expanding the interval between colonoscopies. Objectives: (1) T o describe clinical features, endoscopic images, histopathology of polyps and colorectal cancer of first-degree relatives with colorectal cancer. (2) To determine the relationship between risk polyps and colorectal cancer with some factors. Materials and method: Cross-sectional study analyzing all first-degree relatives aged ≥ 40 years or approximately 10 years younger than the age of the patient diagnosed with colorectal cancer undergoing colonoscopy at the Functional Examination Department, Gia Dinh People’s Hospital during the period from June 2019 to December 2019. Results: In 85 cases: The main features of endoscopy were: rectal polyps 47.3%, sizes < 5 mm 63.9%, multiple polyps 52.7%, sessile 91.7% and smooth surface 88.9%. Regarding histopathological characteristics: the proportion of adenomatous polyps and serrated polyps is nearly equal. Mild dysplasia accounts for the highest rate of 84.2%, high dysplasia accounting for 15.8%. There was 1 case of colorectal cancer, in the sigmoid colon, an ulcerative cancer. Factor related to colorectal polyps and colorectal cancer is age, other factors (gender, smoking, alcohol and abesity) didn’t relate. Conclusion: Our result shows that the majority of polyps are located in the rectum, adenomatous polyps and serrated polyps account for nearly equal proportions, there is a relationship between colon polyps and age, there is no relationship between colon polyps. with gender, smoking, alcohol and obesity.
2.Assessment of left ventricular function in former myocardial infarction patients by using radionuclide ventriculography
Journal of Practical Medicine 2002;435(11):34-37
38 participants of study were divided into two groups. There were 28 subjects (25 males, 3 females) in case group, who had former myocardial infarction (MI) and history of MI. The mean age of case group was 62.5+/-7.4 years. 10 healthy subjects were involved in the control group. It was found that radionuclide ventriculography is a reliable explorative method for evaluation of left ventricular function in the patients with former MI. Sensitivity, specificity and parameters of EFx% (40.3+/-14.0), PER (2.3+/-0.7), 1/3ER (1.9+/-0.8) all decreased significantly in comparison with those of the control group. Left ventricular dysfunction on ventriculography related to site of MI and clinical level of heart failure. In the patient with former MI, there was relative closed correlation between EFx%, 1/3ER and grade of heart failure and PER had modest negative correlation with grade of heart failure
Myocardial Infarction
;
Radionuclide Ventriculography
3.Echo- and radionucleid-ventriculographical study on the change of dimention and the regional dysfunction of left ventricle in patients with old myocardial infarction
Journal of Practical Medicine 2002;435(11):2-6
35 cases of OMI (with an average of 12 months after acute MI) and 44 control subjects were studied by echo- and radionucleidoventriculography. Results shown a larger dilatation of the left ventricle of OMI patients in comparing with the controls. 81.1% of OMI patients had heart wall movement disorders and their location identified by echo was consistent with the MI location diagnosed by ECG. There is a positive proportional relation between WMSI and the severity of heart failure.
Myocardial Infarction
;
Radionuclide Ventriculography
4.Study on the left ventricular systolic- function in the patients with the old cardiac infarction by cardiac ultrasound
Journal of Practical Medicine 2001;394(2):3-6
A cross-sectional discriptive, compare and control study on the 125 patients with the old cardiac infarction and 55 healthy people was carriout in the Army Central Hospital No108 from 3/1995 to 3/1998. The age and sex between 2 groups were the same. The results have shown that the EF% calculated as improved simpson and the interval from point E of the anterior leaf of mitral valve to the left side of the ventricular connection Septal eirs were 2 parameters with the sensitivity and specificity higher than other parameters of ultrasound. The patients with the old cardiac infarction had significantly reduced the left ventricular systolic function. This reduction was corelated with the cardiac infarction. The most reduced the left ventricular systolic function found in the group of the cardiac infarction in the both anterior and posterior septal.
Ventricular Function, Left
;
Infarction
5.Assessment of left ventricular systolic function in patients with old myocardial infarction by radionuclide ventriculography
Journal of Medical and Pharmaceutical Information 2000;(4):29-33
This study was performed on 41 subjects including 10 control subjects aged 57.8+/-6.5 and 31 patients aged 62.5+/-7.4 with old myocardial infarction (OMI), using radionuclide ventriculography (RVG). In conclusion, RVG is a useful method to assess left ventricular systolic function in patients with OMI. Some parameters such as sensitivity, specificity, areas under ROC curve: EF% (93.55; 60.00; 0.912), PER (93.55; 70.00; 0.903) and 1/3ER (93.60; 80.00; 0.929) respectively are higher than those of RVG are. EF% (42.014.9), PER (2.30.7), 1/3ER (1.90.8) in patients with OMI decreased in comparing with the controls. There was a correlation between the classes of clinical heart failure and EF%, PER, 1/3ER respectively (r=-0.52; r=-0.56; r=0.38; p<0.05) in patients with OMI
Myocardial Infarction
;
Radionuclide Ventriculography
6.The change of the left ventricular morphism in patients with the myocardial infarction by ultrasound
Journal of Practical Medicine 1999;359(1):43-47
The research was carried out on 140 patients with previous myocardial infarction and history of typical myocardial infarction, currently with the signs of the previous myocardial infarction by electrocardiogram and the group control of 55 healthy people. Results: the heart beat in the group control and group patient were 73,2+/- 11 and 74,6 +/- 12,7 respectively; the systolic blood pressure in the group control and patients were 77,9+/- 6,4 and 77,8+/- 8,6; respectively. The left ventricular internal dimension and diastole in patients was 61,2+/- 5,6 (mm), the left ventricular length diastolic was 87,9+/-11,3 (mm); the left ventricular area diastole was 44,7+/-10.99 (cm3); the end diastolic volume was 197,1+/- 74,8 (ml). The extend of the left ventricular expansion was direct provisional with the cardiac failure grade and position of the deep septal myocardial infarction.
Myocardial Infarction
;
Ultrasonography
7.A left ventricular form change of patients with old myocardial infarction assessed by echocardiography
Journal of Medical and Pharmaceutical Information 1998;(1):26-31
Echocardiography was done in 104 patients with old myocardial infarction (OMI) and 55 control subjects. Authors found out that patients with OMI accompanying with left ventricular dilation (LVIDd = 50.3+/- 8.5 mm), left ventricular mass (LVM = 187.8+/-60.9 g), and left ventricular mass index (LVMI = 118.5+/-35.7 g/m2) increased compared with control subjects. The level of left ventricular dilation relates with infarct position and quite closely correlates with heart failure class (LVIDd = 39.53 + 5.87 x heart failure; r=0.629; p<0.001). In OMI group, patients accompanying with both anterior and posterior walls, the most dilation is the left ventricular. LVM increase closely correlates with the level of left ventricular dilation (LVIDd = 30.2+0.1 x LVM; r=0.78; p<0.001) and relates lightly with interventricular Septum and diastolic wall thickness (IVSd).
Myocardial Infarction
;
Echocardiography

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