1.Efficacy of intrauterine balloon stent or oral estrogen on prevention of adhesion after transcervical resection of septum in septate uterus: Study protocol for a randomized controlled multicenter study in China.
Shan DENG ; Zichen ZHAO ; Limin FENG ; Xiaowu HUANG ; Sumin WANG ; Xiang XUE ; Lei YAN ; Baorong MA ; Lijuan HAO ; Xueying LI ; Lihua YANG ; Lan ZHU
Chinese Medical Journal 2023;136(24):3016-3018
2.Long-term outcomes of peroral endoscopic myotomy with simultaneous submucosal and muscle dissection (POEM-SSMD) for achalasia with severe interlayer adhesions.
Jiancong FENG ; Ningli CHAI ; Wengang ZHANG ; Longsong LI ; Xiaowei TANG ; Jiale ZOU ; Lu YE ; Enqiang LINGHU
Chinese Medical Journal 2022;135(6):724-726
3.Advances in clinical application of obstruction catheter in prevention and treatment of intestinal obstruction.
Jun Hao FU ; Ning ZHAO ; Bo LIU ; Xue Dong FANG ; Tong CHEN ; Meng ZHANG ; Zhuo LIU
Chinese Journal of Gastrointestinal Surgery 2021;24(10):931-935
		                        		
		                        			
		                        			Intestinal obstruction is one of the most common diseases in abdominal surgery, and its prevention and treatment is a clinical difficulty. Although surgical operation can solve the symptoms of obstruction, there are many postoperative complications, and it is easy to develop re-obstruction due to postoperative abdominal adhesion. The internal fixation of small intestine with obstruction catheter provides a new idea for the prevention of postoperative adhesive bowel obstruction. The use of transanal ileus catheter provides the possibility of direct intestinal anastomosis after resection of malignant obstruction in the left hemicolon and can reduce the incidence of postoperative complications. However, sufficient attention should be paid to the related complications, and prevention and treatment should be planned. It is important to note that the use of obstruction catheter is only one of the conservative treatments for bowel obstruction, and it is not a complete replacement of surgery. Surgical treatment should still be considered, if the catheter fails to significantly move, if the obstructive symptoms do not significantly improve 5 days after catheterization.
		                        		
		                        		
		                        		
		                        			Catheters
		                        			;
		                        		
		                        			Digestive System Surgical Procedures
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intestinal Obstruction/surgery*
		                        			;
		                        		
		                        			Intestine, Small
		                        			;
		                        		
		                        			Tissue Adhesions
		                        			
		                        		
		                        	
4.Case-control study on polymer polylactic acid absorbable medical film for preventing acromion adhesion after arthroscopic rotator cuff repair.
Wei LIN ; Huan XU ; Hai-Lin XING ; Rong-Zong ZHENG ; Jin-He YING
China Journal of Orthopaedics and Traumatology 2018;31(3):228-231
OBJECTIVETo study effect of shoulder joint function after rotator cuff repair of polylactic acid absorbable membrane.
METHODSFrom September 2015 to December 2016, 50 patients diagnosed with rotator cuff tear were selected and divided into treatment group and control group. There were 25 patients in control group, including 12 males and 13 females, with an average age of (48.7±3.5) years old, who received simple arthroscopic rotator cuff repair. There were 25 patients in treatment group, including 11 males and 14 females, with an average age of(49.2±4.1) years old, who performed arthroscopic rotator cuff repair with implanting polylactic acid absorbable membraneon shoulder of rotator cuff. Preoperative and postoperative VAS score, ASES score and UCLA score were recorded and compared between two groups.
RESULTSAt 6 months after operation, preoperative VAS score in control group was 5.48±1.12, and decreased as 1.28±0.84 after operation; ASES score before operation was 52.24±4.64, and improved to 86.92±3.20 after operation;preoperative UCLA score improved from 14.36±1.89 before operation to 30.72±1.28 after operation. In treatment group, VAS score decreased from 5.36±1.32 before operation to 1.40±0.71 after operation;preoperative ASES score was 51.04±4.09, and improved to 88.96±2.79 after operation; UCLA score improved from 15.12±1.81 before operation to 32.12±1.33 after operation. There was no significant difference in VAS score between two groups, and ASES score, UCLA score in treatment group was obviously better than control group.
CONCLUSIONSApplication of polylactic acid absorbable medical membrane could obviously improve shoulder function, and effectively prevent acromion adhesion after arthroscopic rotator cuff repair.
Acromion ; pathology ; Arthroscopy ; Case-Control Studies ; Female ; Humans ; Male ; Middle Aged ; Polyesters ; therapeutic use ; Polymers ; Range of Motion, Articular ; Rotator Cuff ; Rotator Cuff Injuries ; surgery ; Shoulder Joint ; Tissue Adhesions ; prevention & control ; Treatment Outcome
5.Complication of epiduroscopy: a brief review and case report
Maurizio MARCHESINI ; Edoardo FLAVIANO ; Valentina BELLINI ; Marco BACIARELLO ; Elena Giovanna BIGNAMI
The Korean Journal of Pain 2018;31(4):296-304
		                        		
		                        			
		                        			Epiduroscopy is defined as a percutaneous, minimally invasive endoscopic investigation of the epidural space. Periduroscopy is currently used mainly as a diagnostic tool to directly visualize epidural adhesions in patients with failed back surgery syndrome (FBSS), and as a therapeutic action in patients with low back pain by accurately administering drugs, releasing inflammation, washing the epidural space, and mechanically releasing the scars displayed. Considering epiduroscopy a minimally invasive technique should not lead to underestimating its potential complications. The purpose of this review is to summarize and explain the mechanisms of the side effects strictly related to the technique itself, leaving aside complications considered typical for any kind of extradural procedure (e.g. adverse reactions due to the administration of drugs or bleeding) and not fitting the usual concept of epiduroscopy for which the data on its real usefulness are still lacking. The most frequent complications and side effects of epiduroscopy can be summarized as non-persistent post-procedural low back and/or leg discomfort/pain, transient neurological symptoms (headache, hearing impairment, paresthesia), dural puncture with or without post dural puncture headache (PDPH), post-procedural visual impairment with retinal hemorrhage, encephalopathy resulting in rhabdomyolysis due to a dural tear, intradural cyst, as well as neurogenic bladder and seizures. We also report for first time, to our knowledge, a case of symptomatic pneumocephalus after epiduroscopy, and try to explain the reason for this event and the precautions to avoid this complication.
		                        		
		                        		
		                        		
		                        			Brain Diseases
		                        			;
		                        		
		                        			Cicatrix
		                        			;
		                        		
		                        			Epidural Space
		                        			;
		                        		
		                        			Failed Back Surgery Syndrome
		                        			;
		                        		
		                        			Hearing Loss
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Inflammation
		                        			;
		                        		
		                        			Leg
		                        			;
		                        		
		                        			Low Back Pain
		                        			;
		                        		
		                        			Paresthesia
		                        			;
		                        		
		                        			Pharmaceutical Preparations
		                        			;
		                        		
		                        			Pneumocephalus
		                        			;
		                        		
		                        			Post-Dural Puncture Headache
		                        			;
		                        		
		                        			Punctures
		                        			;
		                        		
		                        			Retinal Hemorrhage
		                        			;
		                        		
		                        			Rhabdomyolysis
		                        			;
		                        		
		                        			Seizures
		                        			;
		                        		
		                        			Tears
		                        			;
		                        		
		                        			Tissue Adhesions
		                        			;
		                        		
		                        			Urinary Bladder, Neurogenic
		                        			;
		                        		
		                        			Vision Disorders
		                        			
		                        		
		                        	
6.Choice of the mode of laparoscopic right hemicolectomy.
Chinese Journal of Gastrointestinal Surgery 2017;20(5):504-506
		                        		
		                        			
		                        			Laparoscopy has become the standard surgery mode of right hemicolectomy, including conventional laparoscopy, hand-assisted laparoscopic surgery (HALS), single-port laparoscopic surgery (SPLS), natural orifices translumenal endoscopic surgery (NOTES) and robotic laparoscopy. How to select reasonable laparoscopic mode could be confusing sometimes. For patients, safety, cost-effectiveness and radical cure of the surgery are very important. For doctors, advance and convenience of the surgery must be considered as well. How do we choose a win-win operation method Conventional laparoscopic surgery is the basis of all the minimally invasive surgeries, and total mesocolon resection with D3 lymphadenectomy is an important technical foundation of right hemicolectomy. HALS has some advantages in patients with obesity, abdominal surgery history, intestinal adhesion or intestinal obstruction. SPLS and NOTES have minimized abdominal trauma leading to faster recovery, but have certain technical difficulties, especially NOTES. Although robotic laparoscopic surgery is advanced, but its high cost limits its popularization. Surgeons should integrate their technical levels, hospital equipment, and conditions of patients, then choose reasonable operation mode of right hemicolectomy.
		                        		
		                        		
		                        		
		                        			Abdomen
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Clinical Decision-Making
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Colectomy
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Hand-Assisted Laparoscopy
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intestinal Obstruction
		                        			;
		                        		
		                        			Laparoscopy
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Lymph Node Excision
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Mesocolon
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Minimally Invasive Surgical Procedures
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Natural Orifice Endoscopic Surgery
		                        			;
		                        		
		                        			Obesity
		                        			;
		                        		
		                        			Robotic Surgical Procedures
		                        			;
		                        		
		                        			methods
		                        			;
		                        		
		                        			Tissue Adhesions
		                        			
		                        		
		                        	
7.Efficacy of Percutaneous Epidural Neuroplasty Does Not Correlate with Dural Sac Cross-Sectional Area in Single Level Disc Disease.
Gyu Yeul JI ; Chang Hyun OH ; Bongju MOON ; Seung Hyun CHOI ; Dong Ah SHIN ; Young Sul YOON ; Keung Nyun KIM
Yonsei Medical Journal 2015;56(3):691-697
		                        		
		                        			
		                        			PURPOSE: Percutaneous epidural neuroplasty (PEN) is a minimally invasive treatment. The efficacy of PEN has been relatively well investigated; however, the relationship between the clinical effectiveness of PEN and the severity of spinal canal stenosis by disc material has not yet been established. The purpose of this study was to compare clinical outcomes of PEN according to the dural sac cross-sectional area in single level disc disease. MATERIALS AND METHODS: This study included 363 patients with back pain from single level disc disease with and without radiculopathy. Patients were categorized into groups according to spinal canal compromise by disc material: Category 1, less or more than 50%; and Category 2, three subgroups with lesser than a third, between a third and two thirds, and more than two thirds. Clinical outcomes were assessed according to the Visual Analog Scale (VAS) score for back pain and leg pain and Odom's criteria at 1, 3, 6, 12, and 24 months after treatment. RESULTS: The demographic data showed no difference between groups according to spinal canal compromise by disc material except age (older age correlated with more spinal canal compromise). The dural sac cross-sectional area did not correlate with the VAS scores for back and leg pain after PEN in single level disc disease in Groups 1 and 2. Odom's criteria after PEN were also not different according to dural sac cross-sectional area by disc material. CONCLUSION: PEN is an effective procedure in treating single level lumbar disc herniation without affecting dural sac cross-sectional area.
		                        		
		                        		
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Aged
		                        			;
		                        		
		                        			Back Pain/etiology/*surgery
		                        			;
		                        		
		                        			Dura Mater/*pathology
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Intervertebral Disc
		                        			;
		                        		
		                        			Intervertebral Disc Displacement
		                        			;
		                        		
		                        			Magnetic Resonance Imaging
		                        			;
		                        		
		                        			Male
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Reconstructive Surgical Procedures
		                        			;
		                        		
		                        			Spinal Stenosis/complications/*pathology
		                        			;
		                        		
		                        			Tissue Adhesions/*surgery
		                        			;
		                        		
		                        			Treatment Outcome
		                        			;
		                        		
		                        			Visual Analog Scale
		                        			
		                        		
		                        	
8.The Prognostic Value of Individual Adhesion Scores from the Revised American Fertility Society Classification System for Recurrent Endometriosis.
Bo Hyon YUN ; Young Eun JEON ; Seung Joo CHON ; Joo Hyun PARK ; Seok Kyo SEO ; Sihyun CHO ; Young Sik CHOI ; Ji Sung LEE ; Byung Seok LEE
Yonsei Medical Journal 2015;56(4):1079-1086
		                        		
		                        			
		                        			PURPOSE: This study aimed to evaluate the prognostic value of each component of the revised American Fertility Society (rAFS) classification system for the first recurrence of endometriosis after conservative laparoscopy. MATERIALS AND METHODS: As this was a retrospective cohort study, data were collected by reviewing medical records. A total of 379 women ages 18 to 49 years were included. Women who underwent conservative laparoscopy with histologic confirmation of endometriosis at Gangnam Severance Hospital between March 2003 and May 2010 were included. Individual components of the rAFS classification system as well as preoperative serum CA-125 levels were retrospectively analyzed to assess their prognostic values for recurrence of endometriosis. RESULTS: Of 379 patients, 80 (21.2%) were found to have recurrence of endometriosis. The median duration of follow-up was 19.0 months, and the mean age at the time of surgery was 31.8+/-6.7 years. In endometriosis of advanced stage, younger age at the time of surgery, bilateral ovarian cysts at the time of diagnosis, a rAFS ovarian adhesion score >24, and complete cul-de-sac obliteration were independent risk factors of poor outcomes, and a rAFS ovarian adhesion score >24 had the highest risk of recurrence [hazard ratio=2.948 (95% CI: 1.116-7.789), p=0.029]. CONCLUSION: Our results suggest that of the rAFS adnexal adhesion scores, the ovarian adhesion score rather than the tubal adhesion score was associated with a significantly increased risk of recurrent endometriosis. The preoperative serum CA-125 level may be also a significant prognostic factor for recurrence, as known. However, it seemed to only have borderline significance in affecting recurrence in the current study.
		                        		
		                        		
		                        		
		                        			Adolescent
		                        			;
		                        		
		                        			Adult
		                        			;
		                        		
		                        			Cohort Studies
		                        			;
		                        		
		                        			Endometriosis/*classification/*surgery
		                        			;
		                        		
		                        			Female
		                        			;
		                        		
		                        			Fertility
		                        			;
		                        		
		                        			Follow-Up Studies
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Kaplan-Meier Estimate
		                        			;
		                        		
		                        			Laparoscopy/*methods
		                        			;
		                        		
		                        			Middle Aged
		                        			;
		                        		
		                        			Prognosis
		                        			;
		                        		
		                        			Recurrence
		                        			;
		                        		
		                        			Retrospective Studies
		                        			;
		                        		
		                        			Risk Factors
		                        			;
		                        		
		                        			*Tissue Adhesions
		                        			;
		                        		
		                        			Treatment Outcome
		                        			;
		                        		
		                        			United States
		                        			
		                        		
		                        	
9.Experimental research on the prevention of rabbit postoperative abdominal cavity adhesion with PLGA membrane.
Xiubing PANG ; Yongming PAN ; Fei HUA ; Chaoying SUN ; Liang CHEN ; Fangming CHEN ; Keyan ZHU ; Jianqin XU ; Minli CHEN
Journal of Biomedical Engineering 2015;32(1):146-162
		                        		
		                        			
		                        			The aim of this paper is to explore the prevention of rabbit postoperative abdominal cavity adhesion with poly (lactic-co-glycotic acid) (PLGA) membrane and the mechanism of this prevention function. Sixty-six Japanese white rabbits were randomly divided into normal control group, model control group and PLGA membrane group. The rabbits were treated with multifactor methods to establish the postoperative abdominal cavity adhesion models except for those in the normal control group. PLGA membrane was used to cover the wounds of rabbits in the PLGA membrane group and nothing covered the wounds of rabbits in the model control group. The hematologic parameters, liver and kidney functions and fibrinogen contents were detected at different time. The rabbit were sacrificed 1, 2, 4, 6, 12 weeks after the operations, respectively. The adhesions were graded blindly, and Masson staining and immunohistochemistry methods were used to observe the proliferation of collagen fiber and the expression of transforming growth factor β1 (TGF-β1) on the cecal tissues, respectively. The grade of abdominal cavity adhesion showed that the PLGA membrane-treated group was significant lower than that in the model control group, and it has no influence on liver and kidney function and hematologic parameters. But the fibrinogen content and the number of white blood cell in the PLGA membrane group were significant lower than those of model control group 1 week and 2 weeks after operation, respectively. The density of collagen fiber and optical density of TGF-β1 in the PLGA membrane group were significant lower than those of model control group. The results demonstrated that PLGA membrane could be effective in preventing the abdominal adhesions in rabbits, and it was mostly involved in the reducing of fibrinogen exudation, and inhibited the proliferation of collagen fiber and over-expression of TGF-β1.
		                        		
		                        		
		                        		
		                        			Abdominal Cavity
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Animals
		                        			;
		                        		
		                        			Collagen
		                        			;
		                        		
		                        			metabolism
		                        			;
		                        		
		                        			Lactic Acid
		                        			;
		                        		
		                        			Polyglycolic Acid
		                        			;
		                        		
		                        			Rabbits
		                        			;
		                        		
		                        			Tissue Adhesions
		                        			;
		                        		
		                        			prevention & control
		                        			;
		                        		
		                        			Transforming Growth Factor beta1
		                        			;
		                        		
		                        			metabolism
		                        			
		                        		
		                        	
10.Update on prevention of epidural adhesion after lumbar laminectomy.
China Journal of Orthopaedics and Traumatology 2015;28(11):1064-1068
		                        		
		                        			
		                        			Postoperative epidural adhesion is one of the most common causes of failed back surgery syndrome (FBSS), which can lead to back and leg pain or neurological deficit. Prevention of epidural adhesion after laminectomy is critical for improving the outcomes of lumbar surgery. The main origins of epidural fibrosis are raw surface of erector muscles and rupture fibers of intervertebral disc. The main current preventive methods for epidural adhesion include the usage of implants, chemicals and low dose radiation. However, most of them are still in experiment period. There are still controversies on the clinic usage of autograft free fat, ADCON-L, and Mitomycin C (MMC). The optimal implants are characteristics of better biocompatibility, degradable absorption and capability of existing for a certain period in body. The optimal medicine should have good effect on anti-desmoplasia, less side effects and long half-life. Besides, the combination of biodegradable medical film and drug and the mixture of two or more medical films are also the research frontlines of epidural adhesion. Further researches are required to explore new materials and drugs with stable and most favorable effect in preventing epidural adhesion.
		                        		
		                        		
		                        		
		                        			Biocompatible Materials
		                        			;
		                        		
		                        			administration & dosage
		                        			;
		                        		
		                        			Epidural Space
		                        			;
		                        		
		                        			pathology
		                        			;
		                        		
		                        			Humans
		                        			;
		                        		
		                        			Laminectomy
		                        			;
		                        		
		                        			adverse effects
		                        			;
		                        		
		                        			Lumbar Vertebrae
		                        			;
		                        		
		                        			surgery
		                        			;
		                        		
		                        			Tissue Adhesions
		                        			;
		                        		
		                        			prevention & control
		                        			
		                        		
		                        	
            
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