1.Perioperative outcomes of older adult patients with pancreatic cancer based on nutritional status: a retrospective cohorat study
Takanori MORIKAWA ; Masaharu ISHIDA ; Masamichi MIZUMA ; Kei NAKAGAWA ; Takashi KAMEI ; Michiaki UNNO
Annals of Clinical Nutrition and Metabolism 2025;17(1):66-74
		                        		
		                        			 Purpose:
		                        			This study investigated the effects of preoperative nutritional status on postoperative outcomes in older adult patients with pancreatic adenocarcinoma. 
		                        		
		                        			Methods:
		                        			The background and perioperative factors of patients who underwent pancreatectomy for pancreatic adenocarcinoma between 2007 and 2020 were retrospectively analyzed. 
		                        		
		                        			Results:
		                        			Patients aged 75 years or over (older adults) were significantly associated with hypertension, upfront surgery, and lower prognostic nutritional index. In addition, these patients had a significantly lower rate of portal vein resection, less blood loss, and shorter operation time than patients aged less than 75 years (non-older adults). During the postoperative course, older adult patients had a higher rate of pneumonia and lower overall survival than younger patients, although recurrence‐free survival was comparable. In addition, older adult patients showed preoperative malnutrition as a risk factor for postoperative in‐hospital death. 
		                        		
		                        			Conclusion
		                        			Surgical treatment for pancreatic cancer in older adult patients was performed safely. However, preoperative malnutrition is a risk factor for in‐hospital death and such patients require nutritional support and less‐invasive surgery. 
		                        		
		                        		
		                        		
		                        	
2.Improved visibility of palisade vessels within Barrett’s esophagus using red dichromatic imaging: a retrospective cross-sectional study in Japan
Chise UEDA ; Shinwa TANAKA ; Tetsuya YOSHIZAKI ; Hirofumi ABE ; Masato KINOSHITA ; Hiroya SAKAGUCHI ; Hiroshi TAKAYAMA ; Hitomi HORI ; Ryosuke ISHIDA ; Shinya HOUKI ; Hiroshi TANABE ; Eri NISHIKAWA ; Madoka TAKAO ; Toshitatsu TAKAO ; Yoshinori MORITA ; Takashi TOYONAGA ; Yuzo KODAMA
Clinical Endoscopy 2025;58(2):269-277
		                        		
		                        			 Background/Aims:
		                        			Visualization of palisade vessels (PVs) in Barrett’s esophagus is crucial for proper assessment. This study aimed to determine whether red dichromatic imaging (RDI) improves PV visibility compared with white-light imaging (WLI) and narrow-band imaging (NBI). 
		                        		
		                        			Methods:
		                        			Five expert and trainee endoscopists evaluated the PV visibility in Barrett’s esophagus using WLI, NBI, and RDI on 66 images from 22 patients. Visibility was rated on a 4-point scale: 4, excellent; 3, good; 2, fair; and 1, poor. The color difference between the most recognizable PV spots and surrounding areas with undetectable blood vessels was also analyzed. 
		                        		
		                        			Results:
		                        			Mean visibility scores were 2.6±0.7, 2.3±0.6, and 3.4±0.4 for WLI, NBI, and RDI, respectively. The RDI scores were significantly higher than the WLI (p<0.001) and NBI (p<0.001) scores. These differences were recognized by trainees and expert endoscopists. Color differences in PVs were 7.74±4.96 (WLI), 10.43±5.09 (NBI), and 15.1±6.54 (RDI). The difference in RDI was significantly higher than that in WLI (p<0.001) and NBI (p=0.006). 
		                        		
		                        			Conclusions
		                        			RDI significantly improved PV visibility compared to WLI and NBI based on objective and subjective measures. 
		                        		
		                        		
		                        		
		                        	
3.Perioperative outcomes of older adult patients with pancreatic cancer based on nutritional status: a retrospective cohorat study
Takanori MORIKAWA ; Masaharu ISHIDA ; Masamichi MIZUMA ; Kei NAKAGAWA ; Takashi KAMEI ; Michiaki UNNO
Annals of Clinical Nutrition and Metabolism 2025;17(1):66-74
		                        		
		                        			 Purpose:
		                        			This study investigated the effects of preoperative nutritional status on postoperative outcomes in older adult patients with pancreatic adenocarcinoma. 
		                        		
		                        			Methods:
		                        			The background and perioperative factors of patients who underwent pancreatectomy for pancreatic adenocarcinoma between 2007 and 2020 were retrospectively analyzed. 
		                        		
		                        			Results:
		                        			Patients aged 75 years or over (older adults) were significantly associated with hypertension, upfront surgery, and lower prognostic nutritional index. In addition, these patients had a significantly lower rate of portal vein resection, less blood loss, and shorter operation time than patients aged less than 75 years (non-older adults). During the postoperative course, older adult patients had a higher rate of pneumonia and lower overall survival than younger patients, although recurrence‐free survival was comparable. In addition, older adult patients showed preoperative malnutrition as a risk factor for postoperative in‐hospital death. 
		                        		
		                        			Conclusion
		                        			Surgical treatment for pancreatic cancer in older adult patients was performed safely. However, preoperative malnutrition is a risk factor for in‐hospital death and such patients require nutritional support and less‐invasive surgery. 
		                        		
		                        		
		                        		
		                        	
4.Perioperative outcomes of older adult patients with pancreatic cancer based on nutritional status: a retrospective cohorat study
Takanori MORIKAWA ; Masaharu ISHIDA ; Masamichi MIZUMA ; Kei NAKAGAWA ; Takashi KAMEI ; Michiaki UNNO
Annals of Clinical Nutrition and Metabolism 2025;17(1):66-74
		                        		
		                        			 Purpose:
		                        			This study investigated the effects of preoperative nutritional status on postoperative outcomes in older adult patients with pancreatic adenocarcinoma. 
		                        		
		                        			Methods:
		                        			The background and perioperative factors of patients who underwent pancreatectomy for pancreatic adenocarcinoma between 2007 and 2020 were retrospectively analyzed. 
		                        		
		                        			Results:
		                        			Patients aged 75 years or over (older adults) were significantly associated with hypertension, upfront surgery, and lower prognostic nutritional index. In addition, these patients had a significantly lower rate of portal vein resection, less blood loss, and shorter operation time than patients aged less than 75 years (non-older adults). During the postoperative course, older adult patients had a higher rate of pneumonia and lower overall survival than younger patients, although recurrence‐free survival was comparable. In addition, older adult patients showed preoperative malnutrition as a risk factor for postoperative in‐hospital death. 
		                        		
		                        			Conclusion
		                        			Surgical treatment for pancreatic cancer in older adult patients was performed safely. However, preoperative malnutrition is a risk factor for in‐hospital death and such patients require nutritional support and less‐invasive surgery. 
		                        		
		                        		
		                        		
		                        	
5.Improved visibility of palisade vessels within Barrett’s esophagus using red dichromatic imaging: a retrospective cross-sectional study in Japan
Chise UEDA ; Shinwa TANAKA ; Tetsuya YOSHIZAKI ; Hirofumi ABE ; Masato KINOSHITA ; Hiroya SAKAGUCHI ; Hiroshi TAKAYAMA ; Hitomi HORI ; Ryosuke ISHIDA ; Shinya HOUKI ; Hiroshi TANABE ; Eri NISHIKAWA ; Madoka TAKAO ; Toshitatsu TAKAO ; Yoshinori MORITA ; Takashi TOYONAGA ; Yuzo KODAMA
Clinical Endoscopy 2025;58(2):269-277
		                        		
		                        			 Background/Aims:
		                        			Visualization of palisade vessels (PVs) in Barrett’s esophagus is crucial for proper assessment. This study aimed to determine whether red dichromatic imaging (RDI) improves PV visibility compared with white-light imaging (WLI) and narrow-band imaging (NBI). 
		                        		
		                        			Methods:
		                        			Five expert and trainee endoscopists evaluated the PV visibility in Barrett’s esophagus using WLI, NBI, and RDI on 66 images from 22 patients. Visibility was rated on a 4-point scale: 4, excellent; 3, good; 2, fair; and 1, poor. The color difference between the most recognizable PV spots and surrounding areas with undetectable blood vessels was also analyzed. 
		                        		
		                        			Results:
		                        			Mean visibility scores were 2.6±0.7, 2.3±0.6, and 3.4±0.4 for WLI, NBI, and RDI, respectively. The RDI scores were significantly higher than the WLI (p<0.001) and NBI (p<0.001) scores. These differences were recognized by trainees and expert endoscopists. Color differences in PVs were 7.74±4.96 (WLI), 10.43±5.09 (NBI), and 15.1±6.54 (RDI). The difference in RDI was significantly higher than that in WLI (p<0.001) and NBI (p=0.006). 
		                        		
		                        			Conclusions
		                        			RDI significantly improved PV visibility compared to WLI and NBI based on objective and subjective measures. 
		                        		
		                        		
		                        		
		                        	
6.Perioperative outcomes of older adult patients with pancreatic cancer based on nutritional status: a retrospective cohorat study
Takanori MORIKAWA ; Masaharu ISHIDA ; Masamichi MIZUMA ; Kei NAKAGAWA ; Takashi KAMEI ; Michiaki UNNO
Annals of Clinical Nutrition and Metabolism 2025;17(1):66-74
		                        		
		                        			 Purpose:
		                        			This study investigated the effects of preoperative nutritional status on postoperative outcomes in older adult patients with pancreatic adenocarcinoma. 
		                        		
		                        			Methods:
		                        			The background and perioperative factors of patients who underwent pancreatectomy for pancreatic adenocarcinoma between 2007 and 2020 were retrospectively analyzed. 
		                        		
		                        			Results:
		                        			Patients aged 75 years or over (older adults) were significantly associated with hypertension, upfront surgery, and lower prognostic nutritional index. In addition, these patients had a significantly lower rate of portal vein resection, less blood loss, and shorter operation time than patients aged less than 75 years (non-older adults). During the postoperative course, older adult patients had a higher rate of pneumonia and lower overall survival than younger patients, although recurrence‐free survival was comparable. In addition, older adult patients showed preoperative malnutrition as a risk factor for postoperative in‐hospital death. 
		                        		
		                        			Conclusion
		                        			Surgical treatment for pancreatic cancer in older adult patients was performed safely. However, preoperative malnutrition is a risk factor for in‐hospital death and such patients require nutritional support and less‐invasive surgery. 
		                        		
		                        		
		                        		
		                        	
7.Perioperative outcomes of older adult patients with pancreatic cancer based on nutritional status: a retrospective cohorat study
Takanori MORIKAWA ; Masaharu ISHIDA ; Masamichi MIZUMA ; Kei NAKAGAWA ; Takashi KAMEI ; Michiaki UNNO
Annals of Clinical Nutrition and Metabolism 2025;17(1):66-74
		                        		
		                        			 Purpose:
		                        			This study investigated the effects of preoperative nutritional status on postoperative outcomes in older adult patients with pancreatic adenocarcinoma. 
		                        		
		                        			Methods:
		                        			The background and perioperative factors of patients who underwent pancreatectomy for pancreatic adenocarcinoma between 2007 and 2020 were retrospectively analyzed. 
		                        		
		                        			Results:
		                        			Patients aged 75 years or over (older adults) were significantly associated with hypertension, upfront surgery, and lower prognostic nutritional index. In addition, these patients had a significantly lower rate of portal vein resection, less blood loss, and shorter operation time than patients aged less than 75 years (non-older adults). During the postoperative course, older adult patients had a higher rate of pneumonia and lower overall survival than younger patients, although recurrence‐free survival was comparable. In addition, older adult patients showed preoperative malnutrition as a risk factor for postoperative in‐hospital death. 
		                        		
		                        			Conclusion
		                        			Surgical treatment for pancreatic cancer in older adult patients was performed safely. However, preoperative malnutrition is a risk factor for in‐hospital death and such patients require nutritional support and less‐invasive surgery. 
		                        		
		                        		
		                        		
		                        	
8.Improved visibility of palisade vessels within Barrett’s esophagus using red dichromatic imaging: a retrospective cross-sectional study in Japan
Chise UEDA ; Shinwa TANAKA ; Tetsuya YOSHIZAKI ; Hirofumi ABE ; Masato KINOSHITA ; Hiroya SAKAGUCHI ; Hiroshi TAKAYAMA ; Hitomi HORI ; Ryosuke ISHIDA ; Shinya HOUKI ; Hiroshi TANABE ; Eri NISHIKAWA ; Madoka TAKAO ; Toshitatsu TAKAO ; Yoshinori MORITA ; Takashi TOYONAGA ; Yuzo KODAMA
Clinical Endoscopy 2025;58(2):269-277
		                        		
		                        			 Background/Aims:
		                        			Visualization of palisade vessels (PVs) in Barrett’s esophagus is crucial for proper assessment. This study aimed to determine whether red dichromatic imaging (RDI) improves PV visibility compared with white-light imaging (WLI) and narrow-band imaging (NBI). 
		                        		
		                        			Methods:
		                        			Five expert and trainee endoscopists evaluated the PV visibility in Barrett’s esophagus using WLI, NBI, and RDI on 66 images from 22 patients. Visibility was rated on a 4-point scale: 4, excellent; 3, good; 2, fair; and 1, poor. The color difference between the most recognizable PV spots and surrounding areas with undetectable blood vessels was also analyzed. 
		                        		
		                        			Results:
		                        			Mean visibility scores were 2.6±0.7, 2.3±0.6, and 3.4±0.4 for WLI, NBI, and RDI, respectively. The RDI scores were significantly higher than the WLI (p<0.001) and NBI (p<0.001) scores. These differences were recognized by trainees and expert endoscopists. Color differences in PVs were 7.74±4.96 (WLI), 10.43±5.09 (NBI), and 15.1±6.54 (RDI). The difference in RDI was significantly higher than that in WLI (p<0.001) and NBI (p=0.006). 
		                        		
		                        			Conclusions
		                        			RDI significantly improved PV visibility compared to WLI and NBI based on objective and subjective measures. 
		                        		
		                        		
		                        		
		                        	
9.A Case of Lung Cancer in Which Arthrocentesis and Radiation were Effective in Treating Pain Caused by Malignant Joint Fluid
Hikaru MAMIZU ; Morihiro KUMAGAI ; Chika KUWANA ; Masanori MIYAGATANI ; Maiko MAMIZU ; Daisuke ISHIKAWA ; Hidenori KAWAKAMI ; Toshiki FURUKAWA ; Takashi ISHIDA
Palliative Care Research 2024;19(4):251-255
		                        		
		                        			
		                        			Introduction: We experienced a case of lung cancer in which arthrocentesis and radiation were effective in treating pain caused by malignant joint fluid. Case: An 80-year-old man was referred to our hospital because of right shoulder pain and difficulty in raising his right hand. Whole body computed tomography (CT) showed right lung tumor, multiple liver metastases and multiple bone metastases. There were also bone metastases in the right scapula and joint fluid accumulation in the right shoulder joint. He was irradiated for bone metastases in the right scapula, but the pain remained, although it had not worsened. Therefore, an arthrocentesis of the right shoulder joint was performed and pain was alleviated. In addition, the diagnosis of non-small cell carcinoma was made by joint fluid cytology. A biopsy was also taken from the right lung tumor, and as the histological diagnosis was similar to that of the joint fluid, chemotherapy was started. CT after the start of treatment showed a decrease in the right shoulder joint fluid and no progression of right scapular metastases. Conclusion: In case of malignant joint fluid associated with bone metastases, a severe prognosis is expected, but arthrocentesis and irradiation can reduce pain.
		                        		
		                        		
		                        		
		                        	
10.A Case of Type A Aortic Dissection That Developed Ischemic Cardiomyopathy due to Coronary Malperfusion
Emi NAGATA ; Takashi IGARASHI ; Hirono SATOKAWA ; Tsuyoshi FUJIMIYA ; Hiroharu SHINJO ; Keiichi ISHIDA ; Hitoshi YOKOYAMA
Japanese Journal of Cardiovascular Surgery 2021;50(4):279-282
		                        		
		                        			
		                        			A 57-year-old man complained of dyspnea, and his echocardiography showed diffuse severe left ventricular dysfunction. Five days after admission and starting the treatment for congestive heart failure, a computed tomography pointed out DeBakey type 1 aortic dissection with a patent false lumen incidentally. The ostium of the left coronary artery was compressed with the false lumen, and this finding was thought to be a cause of development of left ventricular dysfunction. A modified Bentall procedure with bioprosthesis and total arch replacement were performed. The patient was discharged on the 28th postoperative day without any complications.
		                        		
		                        		
		                        		
		                        	
            

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