1.A Case of Cardiac Papillary Fibroelastoma Located in Left Atrial Appendage and Cerebral Embolism
Kyohei KAWASAKI ; Takuya MIYAZAKI ; Minoru YOSHIDA ; Tadashi ISOMURA
Japanese Journal of Cardiovascular Surgery 2025;54(2):61-63
		                        		
		                        			
		                        			Cardiac papillary fibroelastoma (PFE) is a benign cardiac tumor that mainly occurs in the valve leaflets of the left heart. The patient was a 72-year-old man diagnosed with cerebral infarction. Contrast-enhanced computed tomography and transesophageal echocardiography revealed a 12-mm mass in the left atrial appendage (LAA), and we decided to undergo emergency cardiac tumor resection due to embolism onset. Postoperative pathological examination revealed an extremely rare cardiac PFE originating in the LAA.
		                        		
		                        		
		                        		
		                        	
2.Mitral Surgery for Severe Mitral Annular Calcification: Calcium Resection or Exclusion Procedure
Minoru YOSHIDA ; Tadashi ISOMURA ; Takuya MIYAZAKI
Japanese Journal of Cardiovascular Surgery 2023;52(3):143-148
		                        		
		                        			
		                        			Background: Extensive calcification of the mitral annulus (MAC) represents a problem for mitral surgery due to a technical difficulty for implanting prosthetic valves, because the calcium does not allow placing direct sutures through the annulus and para-prosthetic leakage or cardiac rupture may result. We describe our experience with mitral valve surgery with or without decalcification of the annulus. Methods: Since 2005, we performed mitral valve operations in 1,327 patients and among them, severe mitral annular calcification was present in 25 (1.9%). Results: The mean age was 75±9 years and there were 6 men and 19 women, with hemodialysis in 4. Mitral valve replacement (MVR) was performed in all patients. A concomitant operation was aortic valve replacement in 19 and coronary artery bypass grafting in 4 patients. The MAC was resected in 14 (Group-R) and was excluded in 11 (Group-E). In-hospital mortality was four patients in Group-R. The cause of death was congestive heart failure in two, cerebellar infarction in one, and respiratory failure in one. Postoperative morbidity included one patient with reexploration and one with prolonged respiratory failure The aortic cross clamp time was a mean of 180±44 min (range 108∼266 min) in Group-R and 139±32 min (range 61∼186 min) in Group-E (p=0.009). The size of the prosthetic mitral valve was 24.3±1.0 mm in Group-R and 24.6±0.8 mm in Group-E (p=0.618). The postoperative echocardiography showed no abnormal mean pressure gradient of mitral valve prosthesis nor para-valvular leak in any patients in either group. Conclusions: The mitral valve replacement without annular decalcification in a severely calcified mitral annulus is a safe and an effective approach in an elderly patient.
		                        		
		                        		
		                        		
		                        	
4.An Operative Case of Chronic Traumatic Thoracic Aortic Aneurysm, 19 Years after a Traffic Accident
Atsushi Yuda ; Akimitu Yamaguchi ; Hisayoshi Suma ; Tadashi Isomura ; Taikou Horii ; Teisei Kobashi ; Takehiko Inoue ; Haruka Makinae
Japanese Journal of Cardiovascular Surgery 2004;33(6):414-416
		                        		
		                        			
		                        			A chronic traumatic thoracic aortic aneurysm, 19 years after a traffic accident was successfully treated. A 34-year-old man was admitted because of chest discomfort. An upper GI examination was performed and an esophageal submembranous tumor was suspected. However, a chest CT examination showed a thoracic descending aortic aneurysm, the maximum size of which was 7.5cm×5.5cm. The final diagnosis was chronic traumatic thoracic aortic aneurysm. Generally most cases of chronic traumatic thoracic aortic aneurysm have no symptoms for a long time after an accident. However, some have reported that the development of an aneurysm is due to not receiving treatment. We performed graft replacement using the temporary bypass method because it was an easy technique and required less heparinization. Chronic thoracic aortic aneurysms have lower risk of bleeding during the operation than acute cases. For chronic cases which have stable hemodynamics, adjunctive methods (e. g., partial extracorporeal bypass, left ventricular bypass and temporary bypass) may facilitate a safe operation.
		                        		
		                        		
		                        		
		                        	
5.Is It Safe to Use Intermittent Warm Blood Cardioplegia for Coronary Artery Bypass Grafting?
Toru Sato ; Tadashi Isomura ; Nobuhiko Hayashida ; Takaya Higashi ; Ikutaro Akasu ; Kouichi Arinaga ; Hiroshi Maruyama ; Shigeaki Aoyagi ; Ken-ichi Kosuga ; Kouichi Hisatomi
Japanese Journal of Cardiovascular Surgery 1997;26(1):27-33
		                        		
		                        			
		                        			Postoperative cardiac function, changes of LV wall motion and exercise tolerance test were studied in 49 patients who received coronary artery bypass grafting (CABG) using antegrade intermittent warm blood cardioplegia (IWBC) and had postoperative left ventriculography (LVG). The mean aortic cross clamp (ACC) time was 68.2±22.8 minutes, and the coronary perfusion time during ACC was 12.6±6.9 minutes (18.2±7.1% of total ACC time). Spontaneous return of normal sinus rhythm was seen in 45 patients (92%). Perioperative myocardial infarction occurred in only one patient and one patient required inotropic support>5μg/kg/min after operation. The mean cardiac index measured by Swan-Ganz catheter improved postoperatively, and the postoperative LVG revealed improvement of the LV wall motion in comparison with that of preoperative LVG, and no local asynergy due to inadequate distribution of IWBC was seen in the early postoperative period. The mean postoperative exercise tolerance performed in 24 patients was 6.6 METS (metabolic equivalents), and no patient revealed myocardial ischemia at exercise. In conclusion, the IWBC is considered to be an easy and safe technique for distal anastomoses of CABG with no influence upon the postoperative cardiac function and LV wall motion.
		                        		
		                        		
		                        		
		                        	
6.Surgical Repair for Aortic Coarctation in Children Aged Less than One Year.
Toru Sato ; Ken-ich Kosuga ; Nobuhiko Hayashida ; Munetaka Kumate ; Tadashi Isomura ; Shigeaki Aoyagi ; Kouichi Hisatomi
Japanese Journal of Cardiovascular Surgery 1997;26(1):34-39
		                        		
		                        			
		                        			The operative results in case of aortic coarctation (CoA) were studied. Between June 1980 and June 1995, 37 children with CoA underwent surgical intervention during their first year of life in our institute. The aortic lesion was repaired by the subclavian flap (SCF) method in 27, direct anastomosis (DA) method in 7, grafting or other methods in 3 children, respectively. The mean follow up period was 7.4±5.3 years (6 months-13 years). Rate of re-stenosis of the aorta was 10% (2 in 20 children) after SCF method, 0% (0 in 7 children) after DA method. The stenotic lesion was successfully dilated by the percutaneous balloon reconstruction in one child. Perioperative mortality was 25% (1/4) in one-stage repair, while one-stage repair was successfully performed in the last three cases and 16.6% (3/18) in two-stage repair for CoA associated with ventricular septal defect (VSD). The mortality was 60% (6/10) of CoA associated with other complex anomalies. In conclusion, one-stage repair seems to be recommendable for the operation of CoA with VSD, and two-stage repair seems to be safe for CoA with complex anomalies.
		                        		
		                        		
		                        		
		                        	
7.Coronary Artery Bypass Grafting in the Presence of Atherosclerotic Lesions in the Ascending Aorta.
Tadashi Isomura ; Toru Satoh ; Nobuhiko Hayashida ; Hiroshi Maruyama ; Kouichi Hisatomi ; Tatsuya Higashi ; Kouichi Arinaga ; Ikutaroh Akasu ; Kenichi Kosuga ; Shigeaki Aoyagi
Japanese Journal of Cardiovascular Surgery 1997;26(2):77-82
		                        		
		                        			
		                        			The results and surgical techniques were studied in 59 patients who had atherosclerotic lesions in the ascending aorta. Arterial grafting (AG) and sequential grafting for coronary artery bypass grafting (CABG) was used in as many as possible cases and the number of distal anastomoses with AG was 1.3/patient (internal thoracic artery (ITA), 56 anastomoses for 50 patients; gastroepiploic artery (GEA), 17; and inferior epigastric artery, 3). Calcification in the ascending aorta was noted in 26 patients and arterial cannulation was performed via the right axillary artery in 4 patients. Saphenous vein grafts were used for 51 patients and 30 of them required aortic reconstruction for proximal anastomosis. There were 2 hospital deaths (non-cardiac) and no neurological complications. It is difficult to perform CABG in the presence of atherosclerosis in the ascending aorta. However, the right axillary artery cannulation as the site of arterial cannulation and the use of sequential grafting, using ITA and GEA as the pedicled arterial conduits are useful to accomplish CABG in such patients. Neurological complication seems to be manufactured at a minimal level by cautious operative techniques.
		                        		
		                        		
		                        		
		                        	
8.Delayed Sternal Closure after Cardiac Operations for Congenital Heart Disease in Infancy.
Toru Sato ; Ken-ichi Kosuga ; Munetaka Kumate ; Tadashi Isomura ; Shigeaki Aoyagi
Japanese Journal of Cardiovascular Surgery 1997;26(4):224-229
		                        		
		                        			
		                        			Among 95 infants aged less than one year who underwent intracardiac repair for congenital heart disease at Kurume University Hospital between August 1990 and June 1995, a patients (3.9%) received primary elective open sternal (PEOS) and delayed sternal closure (DSC) after operation. 1) The mean interval for DSC was 4.3±0.9 (2-8) days, and DSC interval significantly correlated with the extracorporeal circulation (ECC) time. 2) Before DSC, patients became hemodynamically stable and requirements for inotropes and FiO2 for mechanical ventilation decreased. 3) It was important to carefully manage fluid balance before DSC, and the balance after operation should be 0. 4) There was only one patient with mediastinal infection. Of the three patients who died in hospital the cause of death was pulmonary infection due to prolonged mechanical ventilation. 5) Both PEOS and DSC required careful postoperative management, but, the treatment seemed to improve postoperative results in cases in which postoperative hemodynamic status was unstable due to prolonged ECC.
		                        		
		                        		
		                        		
		                        	
9.Surgical Therapy for Juxtarenal Aortic Occlusion.
Satoshi Ohba ; Kenichi Kosuga ; Kenichirou Uraguchi ; Kazunari Yamana ; Hidetoshi Akashi ; Takayuki Fujino ; Shinichi Hiromatu ; Yoshiteru Higa ; Tadashi Isomura ; Kiroku Ohishi
Japanese Journal of Cardiovascular Surgery 1995;24(6):355-358
		                        		
		                        			
		                        			The surgical anatomical bypass (ANA) procedures for juxtarenal aortic occlusion (JAO) have been recently developed. However, there are some critical conditions, in which we should be cautious concerning the indications of ANA. Between 1984 and 1993 in Kurume University Hospital, 17 patients with JAO were operated upon. The most common cheifcomplaint was claudication (70.6%). Acute deterioration due to ischemia was recognized in two patients (11.8%). ANA was performed in 15 patients (88.2%) and extra-anatomical bypass (EXT) in 2 with severe calcification of the aorta (11.8%). Hospital deaths occured in three patients with ANA (17.6%), whose background included two acute deterioration and one cerebral infarction with hemiplegia. As an early postoperative complication, acute renal failure occurred in one patient and subileus in two. In the presence of poor general condition, acute deterioration, or severe aortic calcification, the EXT-procedure is the choice of surgical treatment for JAO.
		                        		
		                        		
		                        		
		                        	
10.Indications and Limitations of IABP Support for Acute Cardiac Failure after Artificial Valve Replacement.
Akio Hirano ; Kouichi Hisatomi ; Eiki Tayama ; Masanori Ohhashi ; Tadashi Isomura ; Kenichi Kosuga ; Kiroku Ohishi
Japanese Journal of Cardiovascular Surgery 1994;23(3):191-195
		                        		
		                        			
		                        			We evaluated the indications and limitations of IABP support for weaning for pump and postoperative heart failure after artificial valve replacement. Driving IABP as cardiac support in cases of acute cardiac failure during and after operation, it is most effective for transient cardiac failure-associated coronary artery spasms during and post operation, but it is not effective and is indeed limited for patients who need long term extracorporeal circulation because of operative technical failure, insufficient cardioplegia and delayed right ventricular failure after operation. The latter groups, in which IABP is insufficiently effective need additional assist devices such as V-A bypass and ventricular assist device (VAD).
		                        		
		                        		
		                        		
		                        	
            

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