2.In Vitro Head-to-Head Comparison of Flow Reduction between Fibered and Non-Fibered Pushable Coils
Jong-Tae YOON ; Boseong KWON ; Joon Ho CHOI ; Sun Moon HWANG ; Mihyeon KIM ; Sungbin HWANG ; Yunsun SONG ; Deok Hee LEE
Neurointervention 2024;19(1):31-38
		                        		
		                        			 Purpose:
		                        			To compare the embolization effects of a non-fibered pushable coil with a conventional fibered pushable coil in an in vitro bench-top experiment. 
		                        		
		                        			Materials and Methods:
		                        			A simplified vascular phantom with 4 channels (1 for the non-fibered coil, 1 for the fibered coil, and 2 for continuous circuit flow) was used. A single coil of the longest length was inserted to evaluate the effect of single-coil embolization, and 3 consecutive coils were inserted to assess the effect of multiple-coil embolization. Post-embolization angiography was performed to obtain flow variables (time to peak [TTP], relative peak intensity [rPI], and angiographic flow reduction score [AFRS]) from time density curves. The packing densities of the two coil types were calculated, and the AFRS of each channel was determined by dividing the TTP by the rPI. 
		                        		
		                        			Results:
		                        			When inserting a single coil, the conventional fibered coil demonstrated better flow reduction, as indicated by a higher AFRS (25.6 vs. 17.4, P=0.034). However, the non-fibered coil exhibited a significantly higher packing density (12.9 vs. 2.4, P=0.001). Similar trends were observed with multiple coils. 
		                        		
		                        			Conclusion
		                        			The conventional fibered pushable coil showed better flow reduction efficiency, while the non-fibered pushable coil had a higher packing density, likely due to the flexibility of the coil loops. A better understanding of the distinct characteristics of different pushable coils can enhance the outcomes of various vascular embolization. 
		                        		
		                        		
		                        		
		                        	
            
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