Objective To evaluate application value of ultrasound elastography combined ultrasound and breast BIRADS classification in the diagnosis of breast cancer. Methods A total of 146 cases of breast lumps were treated with ultrasound elastography breast examination to pathological results as the gold standard,respectively elastic strain rate ratio, elastography score, BIRADS classification and joint benign and malignant breast masses were evaluated to compare diagnostic value of different diagnostic methods. Results The ratio of elastic strain rate of breast cancer diagnosis sensitivity,specificity and accuracy were 83.54%,89.89%,86.90%; elastography score diagnosis of breast cancer sensitivity,specificity and accuracy were 87.34%,92.26%,92.86%; BIRADS classification of breast cancer diagnostic sensitivity, specificity and accuracy were 88.61%,92.13%,90.48%; NO.1 two-linking diagnosis of breast cancer sensitivity,specificity and accuracy were 92.41%,93.26%,92.86%;NO.2 two-linking diagnosis of breast cancer sensitivity,specificity and accuracy were 89.87%,92.13%,91.07%;NO.3 two-linking bivalent three diagnostic sensitivity,specificity and accuracy were 93.67%,93.26%,93.45%;triple diagnosis of breast cancer sensitivity, specificity and accuracy were 96.63%,95.51%,95.83%. Bivalent a law,two French and three triple-linked increase in sensitivity,specificity and accuracy triple law had improved significantly(P<0 . 05). Triple Youden index and Kappa values were the highest,followed by two 3-linking method. Conclusion Ultrasound elastography and ultrasound BIRADS evaluation methods in the diagnosis of breast cancer classification has certain limitations, including two joint evaluation method can improve the sensitivity to a certain extent, but only the elastic strain rate ratio, elastography score,BIRADS classification can provide significant time and triple evaluate the sensitivity,specificity,accuracy,Youden index and Kappa values,has a high value.