Objective:To explore the diagnosis and treatment of pure red cell aplastic anemia (PRCA) caused by parvovirus B19 (HPV-B19)infection after liver transplantation (LT).Methods:Three adult PRCA patients caused by parvovirus B19 infection after LT were reviewed retrospectively.The relevant literatures were collected to sort out the detection methods and treatment of parvovirus B19 infection after LT.Results:All three patients received liver transplantation due to end-stage liver disease with massive intraoperative blood transfusion and smooth postoperative recovery.Severe anemia occurred at 1-2 Months after discharge.Hemorrhagic anemia was excluded after re-admission and PRCA was diagnosed by bone marrow aspiration and next generation sequencing (NGS). After tapering the intensity of immunosuppressive therapy, intravenous immunoglobulin (IVIG) was administered for 7-10 days and hemoglobin soon normalized.A review of 15 recent literatures on HPV-B19 infection after LT revealed that the diagnosis and treatment of parvovirus B19 infection after LT gradually were became same.Conclusions:HPV-B19 infection causes PRCA after LT in adults.Diagnosing with NGS, intravenous injection of immunoglobulin and modification of immunosuppressant regimen may achieve excellent therapeutic efficacies.

Objective To explore the clinical application value of serum tumor abnormal protein (TAP)in early diagnosis of breast cancer.Methods The serum TAP level was determined in 53 hospitalized patients with breast cancer and 65 cases of normal physical examination population as the control group.We further compared the positive rate of TAP in the two groups and the expression level of TAP between different clinical pathological parameters in breast cancer group.Results There was no case of TAP positive in the control group,while the positive rate of TAP was as high as 83.02％ in breast cancer group.TAP positive rate of the patients with negative PR (100.00％) was significantly higher than that of PR positive patients (73.53％)(P=0.019).However there was no significant difference of TAP positive rate between patients with different ages,clinical stages,lymph node metastasis and the different expression of ER,C-erbB2 and Ki67.Conclusion It might be clinically valuable to use TAP expression level as a screening marker for breast cancer in combination with the breast cancer hormone PR.

Objective To discuss the medical consumable materials and its storeroom management techniques. Methods From techniques view, it was thoroughly discussed the concrete operating regulations of applying, check in, check out, storeroom specific management, data statistics and second-level storeroom of consumable materials. Results It basically included all contents of management of consumable materials, It has important directive function for medical consumable materials informational management and department of equipment management. Conclusion Economic benefit and socialeffect can be more exerted through the usage of management techniques of medical consumable materials, and more full-scale service can be provided.

Obiective To study controUing method for curing time of the materials based on isocyanate, and perfect making means and operating rules of transmitting apparatus for the wounded, Methods According to the controlling principles of the rate of chemical reaction, the influencing factors' were studied such as catalyzer, ambient temperature, mixture level of materials and materials volume by experiment. Results By the results of experiments, ambient temperature hasn't an effector impact on eufing time of isocyanate, catalyzer and mixture level of materials only have a little effect or impact on initial reaction time, but materials volume is an important factor of all. Conclusion By the means of experiments, the curing time of isocyanate is only influenced by the volume of materials, and the character is very useful to transmitting apparatus for the wounded in field battle or on-site emergency rescue.

50Hz power frequency interference is the main noise of ECG signal.With the signal processing toolbox of MATLAB,this paper develops a high-performance 50Hz notch filter.The design method is relatively simple compared with other methods and the application result verifies its efficiency.

Objective To discuss aspects of medical equipments data information management techniques:medical equipment information management and hospital equipment management system naming regulations which are the core of hospital medical equipment data information management techniques. Methods From view of techniques,it thoroughly discussed concrete techniques regulations of each part. Results It has important directive function for medical equipments informational management and department of equipment management. Conclusion Establishment of medical equipment information management will promote hospital management level enormously,and more and more emphasis are being placed on it.

With the appearance and development of ultrasonic surgical installation, ultrasonic therapy enters on a new epoch. High-amplitude and high-power ultrasonic vibration produced during the operation, ultrasonic surgical installation can be used to decrease the amount of bleeding or stop bleeding according to the acoustic properties of different tissues. The part where pathological changes happen can be excised selectively by ultrasonic surgical installation. This article introduces the principle, structure, classification and clinical application of ultrasonic surgical installation in detail.

This paper introduces the basic theory of BP neural network and develops a model for assessing bid of medical equipment based on BP neural network. A case is analyzed with the model, and the result shows the high accuracy of it.

This paper describes the structure, operating principles, design method of both software and hardware of a centralized controlling system of infusion pumps based on CAN bus. The system can monitor the status information and control the infusion parameters of many infusion pumps simultaneously. It provides a more complicated cliaical infusion treatment means, greatly eases the work burden on doctors and nurses, and promotes the effects of treatment and nursing.

The development of medical technology and method more and more relies on medical engineering technology.This paper demonstrates the importance of quality management in medical engineering from many aspects,especially from the establishment of medical instrument quality and safety management system.